The Role of Estuaries and Coastal Areas as Nurseries for Fish: Concepts, Methodological Challenges and Future Perspectives

2022 ◽  
pp. 223-238
Author(s):  
Henrique Cabral
Keyword(s):  
Coastal Areas ◽  
Future Perspectives ◽  
Methodological Challenges

The Science of Wisdom in a Polarized World: Knowns and Unknowns

2020 ◽  
Author(s):  
Igor Grossmann ◽  
Nic M. Weststrate ◽  
Monika Ardelt ◽  
Justin Peter Brienza ◽  
Mengxi Dong ◽  
...  
Keyword(s):  
Individual Differences ◽  
Problem Solving ◽  
Best Practices ◽  
Cognitive Sciences ◽  
Methodological Challenges ◽  
The Common ◽  
Empirical Approaches ◽  
And Training ◽  
Contextual Differences

Interest in wisdom in the cognitive sciences, psychology, and education has been paralleled by conceptual confusions about its nature and assessment. To clarify these issues and promote consensus in the field, wisdom researchers met in Toronto in July of 2019, resolving disputes through discussion. Guided by a survey of scientists who study wisdom-related constructs, we established a common wisdom model, observing that empirical approaches to wisdom converge on the morally-grounded application of metacognition to reasoning and problem-solving. After outlining the function of relevant metacognitive and moral processes, we critically evaluate existing empirical approaches to measurement and offer recommendations for best practices. In the subsequent sections, we use the common wisdom model to selectively review evidence about the role of individual differences for development and manifestation of wisdom, approaches to wisdom development and training, as well as cultural, subcultural, and social-contextual differences. We conclude by discussing wisdom’s conceptual overlap with a host of other constructs and outline unresolved conceptual and methodological challenges.

Role of Pharmacogenomics in Antiepileptic Drug Therapy: Current Status and Future Perspectives

2018 ◽  
Vol 23 (37) ◽  
pp. 5760-5765 ◽  
Author(s):  
Antonio Gambardella ◽  
Angelo Labate ◽  
Laura Mumoli ◽  
Iscia Lopes-Cendes ◽  
Fernando Cendes
Keyword(s):  
Drug Therapy ◽  
Antiepileptic Drug ◽  
Current Status ◽  
Future Perspectives ◽  
Antiepileptic Drug Therapy

Doing Tricks

2018 ◽  
Author(s):  
Rodrigo Borba
Keyword(s):  
Public Health ◽  
Feminist Theory ◽  
Sex Work ◽  
Language Use ◽  
Sex Industry ◽  
Commercial Sex ◽  
Business Transaction ◽  
Methodological Challenges ◽  
Social Scientific

Sex work has long been of interest to a variety of fields, among them anthropology, sociology, public health, and feminist theory, to name but a few. However, with very few exceptions, sociolinguistics seems to have ignored the fact that commercial sex, as an intersubjective business transaction, is primarily negotiated in embodied linguistic interaction. By reviewing publications in distinct social scientific areas that directly or indirectly discuss the role of language in the sex industry, this chapter critically assesses the analytical affordances and methodological challenges for a sociolinguistics of sex work. It does so by discussing the “tricks” played by sex work, as a power-infused context of language use in which issues of agency (or lack thereof) are paramount, on sociolinguistic theory and methods. The chapter concludes that the study of language in commercial sex venues is sociolinguistically promising and epistemologically timely.

scholarly journals Therapeutic Role of Tocilizumab in SARS-CoV-2-Induced Cytokine Storm: Rationale and Current Evidence

2021 ◽  
Vol 22 (6) ◽  
pp. 3059
Author(s):  
Corrado Pelaia ◽  
Cecilia Calabrese ◽  
Eugenio Garofalo ◽  
Andrea Bruni ◽  
Alessandro Vatrella ◽  
...  
Keyword(s):  
Review Article ◽  
Lung Damage ◽  
Current Evidence ◽  
Therapeutic Effects ◽  
Cytokine Storm ◽  
Future Perspectives ◽  
Pathogenic Role ◽  
Refractory Rheumatoid Arthritis ◽  
Life Threatening

Among patients suffering from coronavirus disease 2019 (COVID-19) syndrome, one of the worst possible scenarios is represented by the critical lung damage caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-induced cytokine storm, responsible for a potentially very dangerous hyperinflammatory condition. Within such a context, interleukin-6 (IL-6) plays a key pathogenic role, thus being a suitable therapeutic target. Indeed, the IL-6-receptor antagonist tocilizumab, already approved for treatment of refractory rheumatoid arthritis, is often used to treat patients with severe COVID-19 symptoms and lung involvement. Therefore, the aim of this review article is to focus on the rationale of tocilizumab utilization in the SARS-CoV-2-triggered cytokine storm, as well as to discuss current evidence and future perspectives, especially with regard to ongoing trials referring to the evaluation of tocilizumab’s therapeutic effects in patients with life-threatening SARS-CoV-2 infection.

scholarly journals Current role of ultrasound in hemodialysis access evaluation

2021 ◽  
pp. 112972982110346
Author(s):  
Meola Mario ◽  
Jose Ibeas ◽  
Jan Malik
Keyword(s):  
Turning Point ◽  
Point Of Care ◽  
Low Cost ◽  
Wireless Systems ◽  
Future Perspectives ◽  
Maturation Period ◽  
Surveillance Programs ◽  
Dialysis Nurses

Physical examination (PE) is considered the backbone before vascular access (VA) placement, during maturation period and for follow-up. However, it may be inadequate in identifying suitable vasculature, mainly in comorbid patients, or in detecting complications. This review highlights the advantages of ultrasound imaging to manage VA before placement, during maturation and follow-up. Furthermore, it analyses the future perspectives in evaluating early and late VA complications thank to the availability of multiparametric platforms, point of care of ultrasound, and portable/wireless systems. Technical improvements and low-cost systems should favor the widespread ultrasound-based VA surveillance programs. This significant turning point needs an adequate training of nephrologists and dialysis nurses and the standardization of exams, parameters, and procedures.

scholarly journals Phosphorylation of the Regulators, a Complex Facet of NF-κB Signaling in Cancer

Biomolecules ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 15
Author(s):  
Aishat Motolani ◽  
Matthew Martin ◽  
Mengyao Sun ◽  
Tao Lu
Keyword(s):  
Transcription Factor ◽  
Cardiovascular Diseases ◽  
Cancer Progression ◽  
Nuclear Factor Kappa B ◽  
Nuclear Factor ◽  
Malignant Diseases ◽  
Future Perspectives ◽  
Post Translational Modifications ◽  
Site Specific

The nuclear factor kappa B (NF-κB) is a ubiquitous transcription factor central to inflammation and various malignant diseases in humans. The regulation of NF-κB can be influenced by a myriad of post-translational modifications (PTMs), including phosphorylation, one of the most popular PTM formats in NF-κB signaling. The regulation by phosphorylation modification is not limited to NF-κB subunits, but it also encompasses the diverse regulators of NF-κB signaling. The differential site-specific phosphorylation of NF-κB itself or some NF-κB regulators can result in dysregulated NF-κB signaling, often culminating in events that induce cancer progression and other hyper NF-κB related diseases, such as inflammation, cardiovascular diseases, diabetes, as well as neurodegenerative diseases, etc. In this review, we discuss the regulatory role of phosphorylation in NF-κB signaling and the mechanisms through which they aid cancer progression. Additionally, we highlight some of the known and novel NF-κB regulators that are frequently subjected to phosphorylation. Finally, we provide some future perspectives in terms of drug development to target kinases that regulate NF-κB signaling for cancer therapeutic purposes.

Role of Platelet Function Testing in Clinical Practice: Current Concepts and Future Perspectives

2011 ◽  
Vol 12 (12) ◽  
pp. 1836-1847 ◽  
Author(s):  
Dirk Sibbing ◽  
Robert A. Byrne ◽  
Adnan Kastrati
Keyword(s):  
Clinical Practice ◽  
Platelet Function ◽  
Future Perspectives ◽  
Platelet Function Testing ◽  
Function Testing

RHODES AND KOS: EAST DORIAN POTTERY PRODUCTION OF THE ARCHAIC PERIOD

2017 ◽  
Vol 112 ◽  
pp. 99-154 ◽  
Author(s):  
Alexandra Villing ◽  
Hans Mommsen
Keyword(s):  
Neutron Activation Analysis ◽  
Activation Analysis ◽  
Neutron Activation ◽  
Coastal Areas ◽  
Sixth Century ◽  
Pottery Production ◽  
High Quality ◽  
Consistent Feature ◽  
Painted Pottery

To date, the pottery production of Rhodes, Kos and other ‘East Dorian’ islands and coastal areas remains little understood. This article presents and discusses new neutron activation analysis (NAA) of eighth–sixth-century bc vessels found on Rhodes and in related areas, placing them in the wider context of past and present archaeometric research. The results highlight the role of Kos as a leading regional centre of painted pottery production and export in the seventh–sixth centuries bc, notably of ‘East Dorian’ plates. This includes the famous ‘Euphorbos plate’, which can now be attributed to Koan production. Contemporary Archaic pottery workshops on Rhodes, in contrast, had a less ambitious, if diverse, output, ranging from vessels in a Sub-Geometric tradition, imitation Corinthian wares and modest local versions of Koan- and Ionian-style plates to finely potted and richly decorated ‘Vroulian’ cups and black-figured situlae. It was imported mainland and East Greek wares, however, that dominated the island's consumption of Archaic painted wares. This represents a departure from the preceding Geometric period, which was characterised by a local pottery production of considerable scale and quality, although receptivity to external influences remained a consistent feature throughout later periods. As patterns of demand were changing, the island's craft production appears to have concentrated on a different range of goods in which high-quality figured finewares played a lesser role.

The role of dalbavancin for Gram positive infections in the COVID-19 era: state of the art and future perspectives

2021 ◽  
pp. 1-10
Author(s):  
Massimo Andreoni ◽  
Matteo Bassetti ◽  
Salvatore Corrao ◽  
Francesco Giuseppe De Rosa ◽  
Vincenzo Esposito ◽  
...  
Keyword(s):  
State Of The Art ◽  
Future Perspectives ◽  
Gram Positive
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