Frequency of Hepatitis B and C virus infection in Emergency Surgical Patients in Jinnah Hospital, Lahore

2021 ◽  
Vol 15 (10) ◽  
pp. 2584-2586
Author(s):  
Fowad Karim ◽  
Kamran Ali ◽  
Shabbir Ahmad ◽  
Ruqayya Shahid ◽  
Shahbaz Amin

Background: Hepatitis B and C is a global health issue in developing countries because of multiple factors like lack of community health education, illiteracy and poverty. Aim: To find the frequency of Hepatitis B and C virus infection among patients who present in Surgical Emergency and to correlate risk factors for these infections. Study design: Cross sectional study. Methodology: Patients (n=200) were included in present study through non-probability, convenient sampling technique. It was conducted in Accident and Emergency Department, Jinnah Hospital Lahore, following approval from Hospital Ethical Committee from Jan 2018 to Jun 2018. Both male and female patients (12-65 yrs) who underwent emergency surgical procedures, were included while unwilling subjects as well as patients having other medical issues were excluded. Data analyzed by SPSS 21.0v. Results: Thirty four patients were found sero-positive for Anti-HCV Antibodies with prevalence rate of 17.0% and 9 patients (4.5%) were HBsAg positive. Among the sero-positive patients risk factors were IV injections, dental extraction, sharing of shaving razors, jaundice, history of previous surgical operations. Conclusion: This study concluded that there was a declining attitude of HBV infection as compared to HCV. However, educational status of the patients was unsatisfactory. Hence, there is a need to educate the people regarding safety measures. Keywords: Viral infections, HBsAg, Risk Factors and Emergency Surgeries.

2019 ◽  
Author(s):  
Getnet Gedefaw ◽  
Fikadu Waltengus ◽  
Almaz Akililu ◽  
Kihinetu Gelaye

Abstract Objective This study aimed to determine the magnitude of serum HBsAg and the risk factors for Hepatitis B virus infection among pregnant women in Bahir Dar. An institution based cross sectional study was implemented from February 1 to May 1, 2018 among 338 pregnant women attending antenatal care clinic at Felegehiwot referral hospital, Bahir Dar, 2018. Systematic random sampling technique was implemented. Blood sample was taken from 338 study participants and serum was tested for Hepatitis B surface antigen (HBsAg) using Enzyme Linked ImmunoSorbent Assay.Results The overall prevalence of hepatitis B virus infection among pregnant women were 16(4.7%) (95% CI= 2.7, 7.7). Having a history of blood transfusion (AOR=5.2; 95% CI=1.2-22.3), having a history of multiple sexual partners (AOR=4.6; 95% CI=1.1-19.6) and having a history tonsillectomy (traditional surgical procedure) AOR=3.4; 95% CI=1.1-10.1) were the significant risk factors for Hepatitis B virus infection.


Author(s):  
Shatrughan Pareek ◽  
Narendra Kumar Kaushik ◽  
Diwakar Verma ◽  
Anupam Pareek ◽  
Yashawant Ramawat ◽  
...  

Background: Corona virus disease (COVID-19) is declared pandemic by the WHO.  It is a very contagious disease. The global mortality rate of Corona virus disease is around 3.1%. The study was conducted with aim to assess the knowledge and practices towards Corona virus disease among urban population. Awareness towards the disease is important for prevention and control.Methods: The research design was community based descriptive cross-sectional design. The study was conducted in selected urban communities of Bikaner district, Rajasthan. A structured knowledge questionnaire and Practice scale were distributed to subjects from March 2020 to April 2020. In present study, 327 subjects were included in the study by random sampling technique. Data analysis was done using SPSS version 22.0.Results: In the present study, 56.27% were male and 43.73% were female. Nearly 70% participants were graduate and above in educational status. In present study, mostly subjects (76%) have average to good knowledge and practice towards COVID-19. Finding of the study suggests that there was a weak correlation between knowledge and practices of urban people towards corona virus infection. The correlation was not significant (p value=0.1976) at 0.05 level of significance. The study also revealed that knowledge has association with only educational qualification and gender shown association with practices of urban population.Conclusions: Knowledge and practices among population towards the disease are crucial to minimize morbidity and mortality due to the disease. The people have knowledge towards corona virus infection but they are not implementing it into practice. 


2019 ◽  
Author(s):  
Getnet Gedefaw ◽  
Fikadu Waltengus ◽  
Almaz Akililu ◽  
Kihinetu Gelaye

Abstract Objective This study aimed to determine the magnitude of serum HBsAg and the risk factors for Hepatitis B virus infection among pregnant women in Bahir Dar. An institution based cross sectional study was implemented from February 1 to May 1, 2018 among 338 pregnant women attending antenatal care clinic at Felegehiwot referral hospital, Bahir Dar, 2018. Systematic random sampling technique was implemented. Blood sample was taken from 338 study participants and serum was tested for Hepatitis B surface antigen (HBsAg) using Enzyme Linked ImmunoSorbent Assay.Results The overall prevalence of hepatitis B virus infection among pregnant women were 16(4.7%) (95% CI= 2.7, 7.7). Having a history of blood transfusion (AOR=5.2; 95% CI=1.2-22.3), having a history of multiple sexual partners (AOR=4.6; 95% CI=1.1-19.6) and having a history tonsillectomy (traditional surgical procedure) AOR=3.4; 95% CI=1.1-10.1) were the significant risk factors for Hepatitis B virus infection.


2015 ◽  
Vol 2 (1) ◽  
pp. 9-15
Author(s):  
Riaz Gul ◽  
Ahmad Zeb ◽  
Naila Sher

The main objective of the study was to determine the frequency of hepatitis B and hepatitis C in hemodialysis dependent patients who are positive for either type of hepatitis infection.Methodology:Study was conducted for duration of five months (1st Dec 2014- 23rd April 2015) at nephrology unit of Khyber teaching hospital and kidney center of Hayat Abad medical complex. Patients who were dependent on dialysis with renal failure due to any cause were targeted for the study. All patients who were found positive for either type of hepatitis infection were included in the study. All patients who were positive with hepatitis infection before the start of dialysis and those who came for the first time for dialysis were excluded from the study.A semi structured questionnaire with both open and close ended questions was used to collect the information from the patients. Written consent was taken from all the patients prior to the data collection after explaining purpose of the study. It was a cross sectional study and non-probability convenient sampling technique was adopted for the data collection. Total of hundred patients who were positive for hepatitis were taken as sample size. Patient’s record was also thoroughly checked as an adding tool for data collection. Apart from patients some inquiry was also done from the concerned staff working on dialysis machines.Results:Results of this study show that the prevalence of hepatitis infection is more in dialysis dependent patients as compared to the general population, and that among the positive cases the frequency of hepatitis C was more than hepatitis B. Common risk factors associated with increase prevalence of hepatitis infection among hemodialysis dependent patients are frequent blood transfusion without proper screening, lack of proper sterilization of dialysis machine and environment where dialysis is carried out. Close proximity of the patients with positive cases of hepatitis positive patients, previous surgical procedures carried out, history of hepatitis infection in family and decreased immunity of the dialysis patientsConclusions:Frequent dialysis leads to increase frequency of hepatitis C as compared to hepatitis B and unsterilized environment of the area around the machine and unscreened blood transfusion are the major contributors.


2010 ◽  
Vol 162 (3) ◽  
pp. 597-602 ◽  
Author(s):  
Stefanie Hahner ◽  
Melanie Loeffler ◽  
Benjamin Bleicken ◽  
Christiane Drechsler ◽  
Danijela Milovanovic ◽  
...  

ObjectiveAdrenal crisis (AC) is a life-threatening complication of adrenal insufficiency (AI). Here, we evaluated frequency, causes and risk factors of AC in patients with chronic AI.MethodsIn a cross-sectional study, 883 patients with AI were contacted by mail. Five-hundred and twenty-six patients agreed to participate and received a disease-specific questionnaire.ResultsFour-hundred and forty-four datasets were available for analysis (primary AI (PAI), n=254; secondary AI (SAI), n=190). Forty-two percent (PAI 47% and SAI 35%) reported at least one crisis. Three hundred and eighty-four AC in 6092 patient years were documented (frequency of 6.3 crises/100 patient years). Precipitating causes were mainly gastrointestinal infection and fever (45%) but also other stressful events (e.g. major pain, surgery, psychic distress, heat and pregnancy). Sudden onset of apparently unexplained AC was also reported (PAI 6.6% and SAI 12.7%). Patients with PAI reported more frequent emergency glucocorticoid administration (42.5 vs 28.4%, P=0.003). Crisis incidence was not influenced by educational status, body mass index, glucocorticoid dose, DHEA treatment, age at diagnosis, hypogonadism, hypothyroidism or GH deficiency. In PAI, patients with concomitant non-endocrine disease were at higher risk of crisis (odds ratio (OR)=2.02, 95% confidence interval (CI) 1.05–3.89, P=0.036). In SAI, female sex (OR=2.18, 95% CI 1.06–4.5, P=0.035) and diabetes insipidus (OR=2.71, 95% CI 1.22–5.99, P=0.014) were associated with higher crisis incidence.ConclusionAC occurs in a substantial proportion of patients with chronic AI, mainly triggered by infectious disease. Only a limited number of risk factors suitable for targeting prevention of AC were identified. These findings indicate the need for new concepts of crisis prevention in patients with AI.


2018 ◽  
Vol 26 (0) ◽  
Author(s):  
Clarissa Cordeiro Alves Arrelias ◽  
Fernando Belissimo Rodrigues ◽  
Maria Teresa da Costa Gonçalves Torquato ◽  
Carla Regina de Souza Teixeira ◽  
Flávia Fernanda Luchetti Rodrigues ◽  
...  

ABSTRACT Objective: to estimate the prevalence of serological markers for hepatitis B and C in patients with diabetes mellitus and analyze potential associated factors. Method: a cross-sectional study with 255 patients with diabetes mellitus. Demographic, clinical, and risk behavior factors for hepatitis B and C were selected. The markers HBsAg, Anti-HBc IgG, Anti-HBc IgM, Anti-HBs, and Anti-HCV were investigated. A questionnaire and venous blood collection and inferential statistical analysis were used. Results: 16.8% of the patients had a total reactive Anti-HBc marker, 8.2% an isolated Anti-HBs, and 75% were non-reactive for all hepatitis B markers. No case of reactive HBsAg was found and 3.3% of the patients had a reactive anti-HCV marker. The prevalence of prior hepatitis B virus infection was directly associated with the time of diabetes mellitus and the prevalence of hepatitis C virus infection was not associated with the investigated variables. The prevalence of hepatitis B and C infection in patients with diabetes mellitus was higher when compared to the national, with values of 16.8% and 3.3%, respectively. Conclusion: the results suggest that patients with diabetes are a population of higher vulnerability to hepatitis B and C, leading to the adoption of preventive measures of their occurrence.


2019 ◽  
Vol 35 (5) ◽  
Author(s):  
Sidra Hameed ◽  
Faisal Faiyaz Zuberi ◽  
Sagheer Hussain ◽  
Syed Khalid Ali

Objective: To evaluate risk factors having significant effect on mortality of smear positive Pulmonary Tuberculosis (PTB) inpatients. Methods: A descriptive cross-sectional study was conducted at Ojha Institute of Chest Diseases, Dow University Hospital Ojha Campus, Karachi. One hundred and seventy (170) inpatients of smear positive PTB confirmed by Acid Fast Bacilli (AFB) smear, aged between 13-80 years were enrolled by using consecutive sampling technique while patients with drug resistant Tuberculosis (TB) and extra pulmonary TB were excluded from the study. Selected patients were interviewed for collecting demographic data and risk factor data by using a standard questionnaire. Results: Out of 170 PTB inpatients, mortality was observed in 23 (13.5%) patients among which male patients were 12 (52.2%), and female were 11 (47.8%). Mortality was significantly associated with increasing age (p=0.003), socioeconomic status (p=0.019), anemia (p=0.03), Chronic Liver Disease (CLD) (p=0.005), Diabetes Mellitus (DM) (p=0.001), Human Immunodeficiency Virus (HIV) (p=0.007), Hypertension (HTN) (p=0.006), recurrent TB (p=0.001), and smoking (p=0.001). Conclusion: Increasing age, poverty, smoking history, and presence of comorbidities like DM, CLD, HIV, hypertension, and anemia are associated with higher mortality in smear positive PTB cases. doi: https://doi.org/10.12669/pjms.35.5.919 How to cite this:Hameed S, Zuberi FF, Hussain S, Ali SK. Risk factors for mortality among inpatients with smear positive pulmonary tuberculosis. Pak J Med Sci. 2019;35(5):---------. doi: https://doi.org/10.12669/pjms.35.5.919 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Author(s):  
Amina Ehsan ◽  
Farwa Iqbal ◽  
Muhammad Azeem Rao

Abstract Objectives: The objectives of the study were to find out the prevalence of internet addiction and to determine the risk factors associated with internet addiction in medical students. Methods: This descriptive cross-sectional study was carried out at Rawalpindi Medical University, Rawalpindi from July 2018 to August 2019. Our study population included medical students from all the years of MBBS aged 18-25 years, who have been using the internet for the past two years or more. A Stratified random sampling technique was used. Seventy-six self-administered questionnaires were distributed in each year. Data was entered and analyzed using the Statistical Package for Social Sciences (SPSS version 25). Results: Out of the total sample of 380, the prevalence came out to be 90% (n=342). Two hundred and twenty-two 222 (58.4%) had mild, 115 (30.3%) had moderate, six (1.6%) had severe and 37 (9.7%) had no addiction. Out of the risk factors online friendships (p= 0.007), online relationships (P=0.035), online chatting (p= 0.009), online shopping (p= 0.009), online games (p=0.023) and online series/movies (p< 0.000) were statistically significant. Conclusion: The prevalence of internet addiction is high among medical students, which is mostly of a mild type. Internet addiction is more common in males and non-hostel residents. Other significant risk factors are online relationships, online gaming, and online series/movies. Keywords: Prevalence, internet, medical students, risk factors. Continuous...


2018 ◽  
Vol 5 (2) ◽  
pp. 85-89
Author(s):  
Sarita Singh Maharjan

Introductions: Empowerment of women is the process by which women gain power and control over their own lives and acquire the ability to make  choices and decisions. It influences the direction of social change and create a healthy life of self as well as for family. This study aimed to assess the level of empowerment of married women and association with demographic variables. Methods: A cross-sectional study was carried out among married women with children and living with husband, at Kumbhesor ‘tole’ (community) in ward number 11 of Lalitpur Metropolitan City in Kathmandu valley, Nepal, during Jul-Aug 2017. Purposive sampling technique was used. Data were collected through interview using structured questionnaire by door to door visit in community. Results: Total 170 women were interviewed. High level empowerment (score >70%) was seen in 111 (64.5%) and low level empowerment (score ≤50%) in 9 (5.5%) women. Overall empowerment was 75.7±12.3, highest in the dimension of ‘health care decision making’ (82.3±10.5), lowest in ‘educational decision making’ 59.8±21.6. Family type, respondents’ and husband’s educational status had significant association with empowerment. Conclusions: The finding showed that most of the married women in urban community had high empowerment with highest decision making power on health care dimension. Family type and educational status of women and husband were associated factors.


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