scholarly journals Prevalence and Predictors of Dysmenorrhea, its Effects and Coping Mechanism among Adolescent

2021 ◽  
Vol 15 (8) ◽  
pp. 2472-2476
Author(s):  
Nadia Khan Jawad ◽  
Zulfiqar Ali ◽  
Shumaila Khawaja Khail ◽  
Aasia Fozia ◽  
Nadia Pervaiz ◽  
...  
Keyword(s):  
Adolescent Girls ◽  
Management Practices ◽  
Statistical Significance ◽  
Treatment Options ◽  
Cross Sectional Study ◽  
Common Symptom ◽  
Management Options ◽  
Cross Sectional ◽  
Menstrual Symptoms ◽  
Significant Difference

Background and Aim: Dysmenorrhea is one of the most common gynecological disorders in the world. The current study aims to know the prevalence of dysmenorrhea and its management practices among adolescent girls. The study also aim to assess predictors of dysmenorrhea treatment options. Materials and Methods: This institutional-based cross-sectional study was carried out at Obstetrics & Gynaecology department of Mardan Women Hospital, Sheikh Maltoon Town Mardan and Jinnah International Hospital, Abbottabad from June 2020 to November 2020. Pretested self-administrated and a semi-structured questionnaire was used for data collection from volunteer adolescent girls to take part in this study. The outcome and exposure variables association was evaluated through a multi regression model and chi-square test. Dysmenorrhea risk was reported by taking the odds ratio at a confidence interval of 95%. SPSS version 20 was used for data analysis and statistical significance was considered at p<0.05. Results: Of the total 680 questionnaires, 601 (88.4%) were completed. The response rate and dysmenorrhea prevalence were 88.4% and 53.3% respectively. The mean age of the adolescents was 16.3 ± 1.92. While mean age for Menarche was 12.41 ± 1.62. A significant difference (t= 5.78, p< 0.001) between dysmenorrhea and non-dysmenorrhea age girls was (16.81 ±1.98) and (12.56 ± 1.65) respectively. The common symptom of waist pain among participants was (345, 57.4%). The prevalence of participants taking Over-the-counter (OTC) drugs for menstrual symptoms was 191 (31.8%). Dysmenorrhea’s severity and age were the two significant predictors for the prospect of taking a dysmenorrhea pharmacological agent. Conclusion: Our study concluded that a higher prevalence of dysmenorrhea was observed among adolescents compared to Menarche which adversely affects the routine major activities. A significant association between self-reported dysmenorrhea and the abnormal menstrual cycle was found. Adolescents must be educated early on about the safety and efficacy of various dysmenorrhea management options. Keywords: Dysmenorrhea, Adolescence, Menarche

scholarly journals Prevalence and Management of Dysmenorrhea Among Secondary School Adolescents in Enugu State, Nigeria

2020 ◽  
Author(s):  
Amaka Onu ◽  
Deborah Aluh ◽  
Michael Ikehi
Keyword(s):  
Management Practices ◽  
Common Symptom ◽  
Management Options ◽  
Cross Sectional ◽  
Gynecological Disorders ◽  
Menstrual Symptoms ◽  
Significant Difference ◽  
The Mean ◽  
Enugu State ◽  
Descriptive Survey

Abstract Background: Dysmenorrhea is reported to be among the most common gynecological disorders worldwide. The current study aimed to determine the prevalence and management practices for dysmenorrhea among adolescent school girls in Nigeria. The study also aimed to determine the predictors for choosing a management option for dysmenorrhea.Methods: The study was a cross-sectional descriptive survey conducted in five conveniently selected secondary schools (high schools) in Enugu State. A 12-item questionnaire including a Visual Analog Scale was used to collect data. All data were analyzed using SPSS with significance set at p<0.05.Results: A total of 1,486 survey questionnaires were completed (88.45% response rate). The mean age of the study respondents was 15.26±1.517. The prevalence of dysmenorrhea was 51.1%. There was a significant difference (t =-6.299, p < 0.001) between the ages of the dysmenorrheic girls (15.50±1.466) and the ages of girls who were not dysmenorrheic (15.01±1.529). The mean age of Menarche was 12.64±1.450. Pain in the waist was the most common symptom reported among the respondents (57.4%, n = 853). More than one-third of the respondents reported that they take OTC medications for menstrual symptoms (31.8%, n = 472). Age and severity of dysmenorrhea significantly predicted the likelihood of taking a pharmacological agent for dysmenorrhea.Conclusion: Younger females were more likely to do nothing about menstrual pain. There is a need for adolescents to be educated on the safety and efficacy of different management options for dysmenorrhea early.

scholarly journals Menstrual health and related problems in adolescent girls of Lucknow district: a cross sectional study

2018 ◽  
Vol 5 (12) ◽  
pp. 5321
Author(s):  
Geeta Singh ◽  
Anish Khanna ◽  
Monika Agarwal ◽  
V. K. Singh ◽  
Rekha Sachan
Keyword(s):  
Adolescent Girls ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Unequal Distribution ◽  
Urban Girls ◽  
Rural And Urban ◽  
Menstrual Health ◽  
Menstrual Symptoms ◽  
Age Of Menarche

Background: Menstruation and related problems are difficult issues for adolescent girls and are a common reason for consulting healthcare providers. The objective of the study was to study the age of menarche, menstrual pattern, menstrual related health problems and health seeking behaviour for it.Methods: A cross sectional study was carried out in urban as well as rural schools of Lucknow district from August 2014 to September 2015. Multistage random sampling was used to select the requisite number of girls. A total of 600 girls of age group 10-19 years were interviewed and analysed using appropriate statistical methodsResults: The mean age of menarche of the total population was 13.2±1 years. During menstruation, urban girls had significantly excessive passage of clots (26.5%) and faced more discomfort in their routine activities (78.8%) when compared to their rural counterpart (25.2% and 73.4% respectively), whereas the relation was inverse with regard to school absenteeism that was significantly higher in rural girls (44.0%) than urban girls (32.3%). The usual age of menarche as well as the pattern of pre-menstrual symptoms varied significantly between the girls of rural and urban areas.Conclusions: With few exceptions, menstrual health related problems have an unequal distribution in girls of rural and urban origin. Hence effective management of menstrual problems will lose its chase unless health education targeting all the three groups viz.; adolescent girls, concerned parents and teachers have to be uniformly strengthened.

scholarly journals Predictors of low birth weight babies born in tribal tertiary health care setting: a cross sectional study

2018 ◽  
Vol 5 (7) ◽  
pp. 3049
Author(s):  
Thakre S. B. ◽  
Thakre S. S. ◽  
Kaware A. C. ◽  
Adikane H.
Keyword(s):  
Health Care ◽  
Maternal Education ◽  
Care Setting ◽  
Statistical Significance ◽  
Percent Level ◽  
Cross Sectional Study ◽  
Health Care Setting ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference

Background: A baby’s weight at birth is a strong indicator of maternal and newborn health and nutrition. Strategies to reduce prevalence of LBW are important in order to achieve the third Sustainable Development Goals (SDG 3)-reduce child mortality. With this background the present study was undertaken to estimate proportion of LBW babies born at tribal tertiary health care institution and to find out predictors of the LBW among babies.Methods: The present cross sectional study was undertaken at tertiary health care setting. We restricted analyses to singleton live births, and following an initial descriptive summary of the deliveries, logistic regression analysis was conducted to investigate the association of various factors.Results: Our results show proportion of LBW was 17.84% in babies born at tribal tertiary health care setting. There is no significant difference of LBW in different socio-demographics of the mother. However; significant difference was observed in tribal and non-tribal women and women with low literacy lever; wherein significant predictors were related to utilization of antenatal care (ANC), ICDS services, etc. Statistical significance was ascertained based on a p<0.05.Conclusions: In this study; significant predictors were low maternal education, <4 ANC visits, inadequate consumption iron and folic acid, low hemoglobin percent level, and no additional diet at ICDS during current pregnancy. It has also provided basic information pertinent to quality of ANC care and it influence on LBW. Findings of this study are useful for maternal and child health policy makers, practitioners and those who provide health care during pregnancy

scholarly journals Clinicopathological study of ameloblastoma and detection of human papilloma virus by immunohistochemistry

2019 ◽  
Vol 35 (6) ◽  
Author(s):  
Misbah Ali ◽  
Mulazim Hussain Bukhari ◽  
Faiza Hassan ◽  
Maria Illyas
Keyword(s):  
Human Papilloma Virus ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Female Ratio ◽  
Papilloma Virus ◽  
Creative Commons ◽  
Significant Difference ◽  
Clinicopathological Study

Objective: To study the clinocopathological factors and presence of Human Pappiloma Virus in ameloblastoma by immnohistochemistry. Methods: It was a cross sectional study on 50 surgical specimens of ameloblastoma, completed in six months. These were selected and processed for initial screening by H&E and then by immunohistochemistry (IHC) for detection of Human Papilloma Virus (HPV). The questionnaire was designed to study the clinicopathological factors associated in these patients. Sections of 4µm were cut, placed on special positive charged glass slides in the Department of Pathology, King Edward Medical University. It was then examined by the histopathologists for grading and scoring of these lesions. Chi Square test was used to assess the differences found in types of ameloblastomas. The p-value was smaller than 0.05 (p < 0.05). Results: The mean age of the patients (12-80 years old) was 38.6±15.1 years, with male-female ratio 2.84: 1. HPV was positive in 9 (18%), whereas negative in of 41 (82%) patients. Among the positive, reactive HPV with score-1 was 8 and score-2 was 1. According to histological variant, follicular was present in 78%, Plexiform pattern in 8%, Conventional and Desmoplastic variants in one patient each; and Cystic and Acanthomatous were seen in two and three patients respectively. The mandible was involved in 39 patients, maxilla and right maxilla involved in 4 patients each, right retromolar, cheek and angle of mandible was seen in one patient each. About 16% patients had anterior, 66% had posterior and 18% had both anterior and posterior regions involved. Among the HPV positive reactive statistically, no significant difference was found with smoking, Paan and exposure to pesticides, factory or mine (p-value > 0.05). Among HPV positive reactive patients, eight had ameloblastoma whereas, 1 had ameloblastomic fibroma. There was no statistical significance of type, location and region of tumor in HPV positivity. Conclusion: Mandible and posterior region was more commonly involved. Follicular pattern was most common. There was no effect of exposure to pesticides, factory or mine, smoke and human papilloma virus in the etiology of ameloblastoma because only 18% of patients showed the association of HPV16 doi: https://doi.org/10.12669/pjms.35.6.909 How to cite this:Ali M, Bukhari MH, Hassan F, Illyas M. Clinicopathological study of ameloblastoma and detection of human papilloma virus by immunohistochemistry. Pak J Med Sci. 2019;35(6):1691-1696. doi: https://doi.org/10.12669/pjms.35.6.909 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Multiple sclerosis patients and e-health system in Saudi Arabia

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Foziah Alshamrani ◽  
Hind Alnajashi
Keyword(s):  
Multiple Sclerosis ◽  
Treatment Adherence ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Adherence To Treatment ◽  
Related Factors ◽  
Cross Sectional ◽  
Content Type ◽  
Significant Difference ◽  
Multiple Sclerosis Patients

Purpose Multiple sclerosis (MS) is a chronic autoimmune neurological disease. Disease-modifying therapies (DMTs) are mainstay lifelong treatment with no immediate benefits observed. Adherence to treatment is necessary, however, non-adherence is common problem in MS patients. This paper aims to evaluate patient-related factors and satisfactions affecting medication adherence in Saudi MS patients and their rights to discontinue them against medical advice. Design/methodology/approach In total, 409 patients diagnosed with MS, using self-administered DMT (oral and injectable), were randomly enrolled in a cross-sectional study. Electronic questionnaire was used in data collection. Findings Most participants (71.1%) did not know about their MS type. Average age of participants when diagnosed with MS was 27.9 ± 8 years (range 7–69), mean disease duration was 8.1 ± 6.6. Most patients received injectable therapy 363 (88%). Overall adherence in our sample was 67%. Age of participants and duration of disease had no impact on treatment adherence. No significant differences found between genders, educational level, marital status, and smoking in relation to treatment adherence. Route of administration did not reach statistical significance despite a higher percentage of adherence reported in patients on oral DMT [33% (n = 15)] versus injectable therapy [29% (n = 104)]. Conversely, there was significant difference between adherent and non-adherent patients according to anxiety (p = 0.002) and family history of MS (p = 0.011). Originality/value The results revealed that the age of the participants and the duration of the disease had no impact on adherence to treatment.

Social impact of menstrual problems among adolescent school girls in rural Tamil Nadu

2017 ◽  
Vol 30 (5) ◽  
Author(s):  
Rama Ravi ◽  
Pankaj B. Shah ◽  
Shanthi Edward ◽  
Palani Gopal ◽  
B.W.C. Sathiyasekaran
Keyword(s):  
Adolescent Girls ◽  
Tamil Nadu ◽  
Social Impact ◽  
Statistical Significance ◽  
Holistic Approach ◽  
Cross Sectional Study ◽  
Study Data ◽  
Psychosocial Impact ◽  
Cross Sectional ◽  
Increased Risk

Abstract Background Adolescence is a period of physiological, psychological and social transition between childhood and adulthood and is characterized by the onset of menstruation in girls. A adolescent girls are naïve about menstruation and they take time to adapt to these changes both socially and psychologically. This study was carried out to assess the psychosocial impact of menstrual problems among schoolgoing adolescent girls. Methods This study is a cross-sectional study carried out in 350 schoolgoing adolescent girls in the year 2012 in the Thiruvallur district of Tamil Nadu. Girls who attained menarche 1 year prior to the data collection were included in the study. Data regarding background characteristics and psychosocial impact of menstrual problems were collected. Data was analyzed using SPSS ver. 15 software. The χ2-test was carried out to assess the statistical significance at the 95% level of significance. Results The mean age of the participants was 14.7 years. In this study, 87.7% of the girls had at least one menstrual problem. Among these, 78.5% could not attend school during menstruation, 51.1% were unable to perform household/sports activities (p < 0.001). It was observed that dysmenorrhea and menorrhagia were at increased risk of absenting the girls from school (p < 0.05). Conclusion The key to a sound adolescent health programme is a holistic approach which also focuses on the psychological and social domain of health. This could be achieved by involving all the stakeholders like parents, teachers, etc. to work as a team. It is also essential to develop adolescent friendly health services at the grass root level.

scholarly journals Circulating ERBB3 levels are inversely associated with the risk of overweight-related hypertension: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lijun Zhu ◽  
Zhengmei Fang ◽  
Yuelong Jin ◽  
Weiwei Chang ◽  
Mengyun Huang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Conditional Logistic Regression ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Chinese Patients ◽  
Enzyme Linked Immunosorbent Assay ◽  
Cross Sectional ◽  
Significant Difference ◽  
Healthy Control ◽  
Independent Risk Factors

Abstract Background Hypertension and overweight are independent risk factors for cardiovascular disease, and overweight increase the risk of developing high blood pressure. ERBB3( also known as HER3) plays a considerable role in the development of cardiovascular diseases. However, the effect of ERBB3 levels in hypertensive overweight patients is unknown. The aim of this study was to assess the association between ERBB3 levels and hypertension in overweight Chinese patients. Methods We evaluated the height,weight, blood pressure, biochemical indicators, and ERBB3 levels in 128 Chinese adults aged 33–79 years. Plasma ERBB3 levels were assessed by the enzyme-linked immunosorbent assay, and body mass index(BMI) was calculated as body weight divided by height squared. Participants were allocated into three groups according to blood pressure and BMI: healthy control (CNT, n = 31; normotensive and non-overweight), hypertension (HT, n = 33; hypertension and non-overweight), and hypertension with overweight (HTO, n = 64; hypertension and overweight). Statistical significance was defined as a two-tailed P < 0.05. Results There was no significant difference in mean ERBB3 levels among the three groups, although a linear decrease from CNT (1.13 ± 0.36), HT (1.03 ± 0.36), to HTO (0.84 ± 0.26 ng/mL) was observed in men (P = 0.007). Among the drinking population, the ERBB3 level was significantly reduced in the HTO group as compared with those of the CNT and HT groups (0.76 ± 0.23 versus 1.18 ± 0.37 and 1.20 ± 0.30, respectively). ERBB3 levels were negatively correlated with diastolic blood pressure in men (r= − 0.293, P = 0.012), smoking (r= − 0.47, P = 0.004), and drinking (r = − 0.387, P = 0.008). BMI in men and among drinkers, and uric acid among drinkers were negatively correlated with ERBB3 levels. Multivariate conditional logistic regression showed that plasma ERBB3 levels were associated with a reduced risk of HTO in men [odds ratio (OR) 0.054; 95 % confidence interval (CI): 0.007–0.412) and drinkers (OR 0.002; 95 % CI: 0.000–0.101). Conclusions ERBB3 may contribute to the pathogenesis of hypertension in overweight patients, with BMI, gender, and drinking all potentially modulating the process.

scholarly journals Diagnósticos de enfermagem para idosos frágeis institucionalizados

2019 ◽  
Vol 13 (4) ◽  
pp. 966
Author(s):  
Bruna Karen Cavalcante Fernandes ◽  
Abna Gomes Soares ◽  
Brena Valdivino Melo ◽  
Willan Nogueira Lima ◽  
Cintia Lira Borges ◽  
...  
Keyword(s):  
Statistical Significance ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Dry Skin ◽  
Cross Sectional ◽  
Term Care ◽  
Impaired Vision ◽  
Significant Difference ◽  
Nursing Diagnoses

RESUMO Objetivo: elaborar diagnósticos de Enfermagem para idosos frágeis institucionalizados. Método: trata-se de um estudo quantitativo, descritivo, transversal, com 53 idosos em uma Instituição de Longa Permanência para Idosos. Utilizaram-se a escala de fragilidade de Edmonton e um instrumento de coleta de dados baseado em Henderson. Fundamentaram-se os diagnósticos na CIPE®, versão 2015. Analisaram-se os dados nos softwares SPSS e Stata apresentando-os em tabela. Resultados: elaboraram-se 178 diagnósticos de Enfermagem dos quais prevaleceram 15 em mais de 20% da amostra. Destacaram-se “Risco de Queda” (84,9%), “Visão prejudicada” (49,1%), “Marcha prejudicada” (37,7%), “Insônia” (28,3 %), “Sono prejudicado” (26,4%), “Humor deprimido” (24,5%) e “Pele seca” (24,5%). Obteve-se significância estatística entre “Risco de queda” (p = 0,008) e “Pele seca” (p= 0,021) e o nível de fragilidade. Houve, ainda, significância entre o número de diagnósticos e o nível de fragilidade (p<0,001) de modo que, quanto maior o nível de fragilidade, mais diagnósticos. Conclusão: elaborou-se 178 diagnósticos de Enfermagem, dos quais prevaleceram 15, sendo o “Risco de queda” o mais prevalente. Contribuir-se á com esse estudo para divulgar a linguagem diagnóstica CIPE® e sensibilizar os enfermeiros acerca da importância de seu uso.  Descritores: Enfermagem; Terminologia; Diagnóstico de Enfermagem; Idoso; Instituição de longa permanência para idosos; Fragilidade.ABSTRACT Objective: to elaborate nursing diagnoses for institutionalized frail elderly. Method: this is a quantitative, descriptive, cross-sectional study with 53 elderly people in a Long-Term Care Institution for the Elderly. The Edmonton Frailty Scale and a Henderson-based data collection instrument were used. The diagnoses were based on CIPE®, version 2015. Data was analyzed in the SPSS and Stata software and presented in a table. Results: 178 Nursing diagnoses were elaborated, of which 15 were prevalent in more than 20% of the sample. "Impaired vision" (49.9%), "impaired vision" (37.7%), "insomnia" (28.3%), "impaired sleep" "(26.4%)," depressed mood "(24.5%) and" dry skin "(24.5%). Statistical significance was obtained between "Risk for falls" (p = 0.008) and "Dry skin" (p = 0.021) and the level of frailty. There was also a significant difference between the number of diagnoses and the level of frailty (p <0.001), so that the higher the level of frailty, the more diagnoses. Conclusion: 178 Nursing diagnoses were elaborated, of which 15 prevailed, being the "Risk for fallsing" the most prevalent. It will contribute to this study to disseminate the diagnostic language ICNP® and to make nurses aware of the importance of its use. Descriptors: Nursing; Terminology; Nursing diagnosis; Old man; Long-term institution for the elderly; Frailty.RESUMEN Objetivo: elaborar diagnósticos de enfermería para ancianos frágiles institucionalizados. Método: se trata de un estudio cuantitativo, descriptivo, transversal, realizado con 53 ancianos en una Institución de Larga Permanencia para ancianos. Se utilizaron la escala de fragilidad de Edmonton y un instrumento de recolección de datos basado en Henderson. Se fundamentaron los diagnósticos en la CIPE®, versión 2015. Se analizaron los datos en el software SPSS y Stata presentándolos en tabla. Resultados: se elaboraron 178 diagnósticos de Enfermería de los cuales prevalecieron 15 en más del 20% de la muestra. Se destacaron “Riesgo de Caída” (84,9%), “Visión perjudicada” (49,1%), “Marcha perjudicada” (37,7%), “Insomnio” (28,3%), “Sueño perjudicado” (26,4%), "Humor deprimido" (24,5%) y "Piel seca" (24,5%). Se obtuvo significancia estadística entre "Riesgo de caída" (p = 0,008) y "Piel seca" (p = 0,021) y el nivel de fragilidad. Se observó una correlación entre el número de diagnósticos y el nivel de fragilidad (p <0,001), de modo que, cuanto mayor sea el nivel de fragilidad, más diagnósticos. Conclusión: se elaboraron 178 diagnósticos de Enfermería, de los cuales prevalecieron 15, siendo el "Riesgo de caída" el más prevalente. Se contribuirá con este estudio para divulgar el lenguaje diagnóstico CIPE® y sensibilizar a los enfermeros acerca de la importancia de su uso. Descriptores: Enfermería; Terminología; Diagnóstico de Enfermería; Anciano; Hogares para Ancianos; Fragilidad.

scholarly journals Relationship between intake of artificial sweeteners and body mass index in young non-diabetic adults: a cross-sectional study

2017 ◽  
Vol 5 (4) ◽  
pp. 1208
Author(s):  
Geetika Gupta ◽  
Sabita Yograj ◽  
Anil K. Gupta ◽  
Bhavna Langer ◽  
Mumtaz Goni ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
English Language ◽  
Healthy Lifestyle ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Artificial Sweeteners ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference

Background: Artificial sweeteners have skyrocketed the market in the last decade and there are unlimited products available today that contain them. They are often projected as one of the easy and effortless method of cutting down calories and have gained importance in the community. They are being used as one of the dietary tools to control or prevent weight gain not only in diabetic adults but also in young healthy adults and children. There is a need to examine any possible contribution of these substances on body weight and BMI of an individual.Methods: A cross sectional study was conducted among randomly selected healthy non-diabetic subjects of both sexes in the age group 18-35 years. Those with history of intake of artificial sweeteners in the last one year (in the form of pellets or diet soda) were considered as study group and equal no of non-users were taken as comparison group for study purpose. A pretested semi structured questionnaire prepared in English language was used to collect information. Variables such as height, weight and body mass index were noted. Data was analyzed using SPSS (version 20.0).Results: There was a statistically significant difference between the two groups in terms of weight and BMI (p=0.003 and 0.002 respectively). The mean weight and BMI was more in those subjects who had consumed more than one serving of diet can per day. Sweeteners in pellet form failed to show any statistical significance association between frequency of use and BMI.Conclusions: The study suggested of a possible association between the use of artificial sweeteners and BMI. Young adults need to be sensitized about various safe weight management techniques and healthy lifestyle, rather than resorting to methods like intake of artificial sweeteners.

scholarly journals Microalbuminuria among children with congenital heart disease seen in Sokoto, North-Western Nigeria

2021 ◽  
Vol 8 (3) ◽  
pp. 414
Author(s):  
Khadijat O. Isezuo ◽  
Usman M. Sani ◽  
Usman M. Waziri ◽  
Bilkisu G. Ilah ◽  
Fatima B. Jiya ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
Elisa Technique ◽  
Weak Negative Correlation

Background: Congenital heart disease (CHD) especially cyanotic CHD has been associated with microalbuminuria which is an early marker of glomerular nephropathy but this has hardly been studied in African children. The aim of this study was to compare mean microalbuminuria levels and associations among children with acyanotic CHD, cyanotic CHD and normal controls.Methods: Forty-one (41) children comprising 19 acyanotic CHD, 14 cyanotic CHD and 8 without CHD aged 1 to 15 years were recruited in a cross-sectional study. Quantitative urinary microalbuminuria was measured by ELISA technique. Positive result was microalbuminuria of 30-300 mcg/mgCr. Mean levels were compared by student t-test and analysis of variance (ANOVA). Statistical significance was taken at p<0.05.Results: There were 22 (53.7%) females and 19 (46.3%) males. Mean level of microalbuminuria was highest in those with cyanotic CHD at 147.7±78.8 mcg/mgCr, followed by those with acyanotic CHD at 111.8±61.5 mcg/mgCr and lowest in those without CHD at 67.3±31.6 mcg/mgCr. There was significant difference between the groups with CHD and those without CHD (F=4.1, p=0.03) and microalbuminuria had a significant but weak negative correlation with oxygen saturation implying that microalbuminuria increased with worsening cyanosis.Conclusions: Microalbuminuria was high among the patients with CHD, though higher in cyanotic patients warranting closer follow up of these patients.

Sign in / Sign up

Export Citation Format

Share Document