AMINO ACID, FATTY ACID AND VITAMIN COMPOSITION OF ROSA CANINA L.

The genus rose hips, or rose (Rosa L.), belongs to the Rosaceae family. It has many cultural forms, bred under the general name Rose. Now, more than 400 species of rose hips known. Usually these are erect shrubs, less often lianas, sometimes-low tree-like forms or almost herbaceous plants. Rosehip is common in the temperate and subtropical zones of the Northern Hemisphere, it can often found in the mountainous regions of the tropical belt. Some types of rose hips distributed from the Arctic Circle in the north to Ethiopia in the south. On the American continent - from Canada to Mexico. The most favorable conditions for Rosehip are in the Mediterranean region. Several species of the genus Rosehip have a wide distribution area. Kazakhstan possesses significant resources of medicinal plant raw materials. Among the most priority representatives of the wild flora are species of the wild rose genus - Rosa L. as the most valuable medicinal plant. In total, 21 species of wild rose grow in the republic, including 5 in Central Kazakhstan: R. glabrifolia - w. naked, R. laxa Retz. - w. loose, R. acicularis Lindl. - (w. Spiny), R. majalis Herrm. (R. cinnamomea L.) - w. May (w. cinnamon) and R. pimpinellifolia L. (R. spinosissima L.) - w. femoral. Kazakh species of the genus Rosa L Rosehip fruits distinguished by a high content of biologically active substances and are widely used in medicine. Plant raw materials collected in the southern region of the Republic of Kazakhstan (Almaty region). The crushed air-dry raw material was extracted with hexane and chloroform in a raw material-reagent ratio (1:10) in a Soxhlet apparatus. Plants of the genus Rosa are rich in vitamins A, C, E and group B, and also contain sugars, flavonoids, saponins, phytosterols, glycosides, tannins, organic acids, amygdalin, essential oils. Thus, rosehip is a promising raw material for the creation of domestic medicines. This article examines the study of the quantitative composition of amino acids and vitamins in the fruits of the species of the genus Rosa widespread in Kazakhstan in the supercritical extract, isolated and the fruits of the Rosa canina plant, in order to establish the possibility of using and with the subsequent cultivation of the selected species.

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PHYTOCHEMICAL COMPOSITION OF LIPOPHILIC FRACTION OF PLANTS OF THE PLANT ROSA CANINA L. GENUS ROSA

SERIES CHEMISTRY AND TECHNOLOGY ◽

10.32014/2020.2518-1491.25 ◽

2020 ◽

Vol 2 (440) ◽

pp. 69-74

Author(s):

Y.S. Ikhsanov ◽

G.E. Tasmagambetova ◽

Y.A. Litvinenko ◽

G.Sh. Burasheva ◽

G.A. Seitimova

Keyword(s):

Comparative Analysis ◽

Raw Materials ◽

Biologically Active ◽

The Arctic ◽

Distribution Area ◽

Gas Chromatograph ◽

Tropical Zone ◽

Rosa Canina ◽

Soxhlet Apparatus ◽

The Republic

The genus of wild rose, or Rosa L., belongs to the family Rosaceae. It has many cultural forms, bred under the general name Rosa. At the moment, more than 400 species of rose hips are known. Usually these are upright shrubs, less often creepers, sometimes low tree-like forms or almost herbaceous plants. Rosehip is common in the temperate and subtropical zones of the Northern Hemisphere, it can often be found in the mountainous regions of the tropical zone. Some species of rose hips are common from the Arctic Circle in the north to Ethiopia in the south. On the American continent - from Canada to Mexico, Favorable conditions for Rosehip are in the Mediterranean region. Several species of the Rosehip genus have an extensive distribution area. Kazakhstan has significant resources of medicinal raw materials of plant origin. Among the most priority representatives of the wild flora are species of the rosehip genus - Rosa L. as a most valuable medicinal plant. In total, 21 species of wild rose grow in the republic, including 5 in the central Kazakhstan: R. glabrifolia - sh. naked, R. laxa Retz. - w. loose, R. acicularis Lindl. - (W. needlefish), R. majalis Herrm. (R. cinnamomea L.) - sh. May (W. cinnamon) and R. pimpinellifolia L. (R. spinosissima L.) - W. femoral cell. Kazakhstan species of the genus Rosa L. Rose hips are characterized by a high content of biologically active substances and are widely used both in medicine and in cooking. In this paper, a comparative analysis of rose hips, Rosa canina L., harvested in the fall of 2018 is carried out. Plant raw materials are collected in the southern region of the Republic of Kazakhstan (Almaty region). The crushed air-dry raw materials were extracted with hexane and chloroform in the ratio of raw materials-reagent (1:10) in a Soxhlet apparatus. The resulting extract was concentrated under mild conditions to a thick concentrate, which was analyzed on a gas chromatograph with a mass selective detector. The analyzes were carried out on a gas chromatograph with a mass spectrometric detector 6890N / 5973C (Agilent, USA). The peaks detected in the chromatograms were identified using the NIST’11 and Wiley 10 mass spectral libraries. The article first studied and conducted a comparative analysis of lipophilic substances contained in the fruits of the plant Rosa canina L, harvested in the Almaty region. The extracts mainly include hydrocarbons, derivatives of higher carboxylic acids, higher alcohols and some other substances, in particular butyl tetradecyl ether of hydrochloric acid, [4- (2-methylpentanoylsulfamoyl) phenyl] amide of 2-methylpentanoic acid in hexane extract and, butyl undecyl ether sulfuric acid, eicosyl trifluoroacetate and ethoxycarbonyl-3-methyl-4-azafluorenone, 2-fluorenilim in the chloroform extract. Further work will be continued in order to determine the potential biological activity of the obtained extracts. Keywords: Rosa canina L., СКФ-экстракция, никотин, GC-MS, химический состав.

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Investigation of Walnut Herbal Drug Raw Material

Drug development & registration ◽

10.33380/2305-2066-2019-8-4-38-46 ◽

2019 ◽

Vol 8 (4) ◽

pp. 38-46

Author(s):

N. V. Chebyshev ◽

A. V. Strelyaeva ◽

D. I. Lezhava ◽

A. N. Luferov ◽

N. V. Bobkova ◽

...

Keyword(s):

Mass Spectrometry ◽

Medicinal Plant ◽

Raw Materials ◽

Juglans Regia ◽

Biologically Active Substances ◽

Biologically Active ◽

Raw Material ◽

Alcohol Extract ◽

Plant Raw Materials ◽

Active Substances

Introduction. Walnut (Juglans regia L.) is a medicinal plant containing a large number of biologically active substances. A number of authors propose to use walnut leaves as medicinal raw materials, in which juglone, flavonoids, tannins, ascorbic acid and other substances are identified. Currently, a standardization technique for this type of raw material has been developed and proposed. However, the medicinal plant walnut can be a source of other types of raw materials, such as milky-waxed walnuts, walnut bark, and walnut partitions. These types of medicinal raw materials contain a large number of biologically active substances and have a great potential for pharmacological activity. Therefore, the study with the subsequent standardization of medicinal plant material of walnut fruits in the stage of milk-wax ripeness and walnut bark is relevant.Aim. The aim of the study is to study the external signs, microscopy of raw walnut bark and walnut fruit in the stage of milky-wax ripeness and chemical composition of alcohol extract from these types of raw materials.Materials and methods. Chromato-mass spectrometry and TLC were used in the work.Results and discussion. When describing external signs and microscopy, diagnostic signs of both whole and crushed raw materials, and powder of walnut bark, and fruits of walnut in the stage of milky-wax ripeness were revealed. Alcohol extract obtained from medicinal plant raw materials walnut bark is a clear brown liquid. Alcohol extract obtained from medicinal plant raw materials of walnut fruit at the stage of milky-wax ripeness is a transparent, green-brown liquid with a fragrant odor.Conclusion. Gallic acid was identified by TLC in walnut bark. Chromato-mass spectrometry in alcohol extraction from the fruit of walnut in the stage of milky-wax maturity was able to identify 17 compounds belonging to different classes of biologically active substances. Sugars, flavonoids, coumarin phenolic compounds, organic acids were identified. In alcoholic extraction from the bark of a walnut, marker compounds have been determined, the combination of which makes it possible to quickly identify this type of raw material using chromatography-mass spectrometry.

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Pulsatilla alba: analytical review of spread, chemical composition, biological activity and medical application

ScienceRise Biological Science ◽

10.15587/2519-8025.2021.249850 ◽

2021 ◽

pp. 10-14

Author(s):

Anna Krvavych ◽

Nataliia Reviakina ◽

Lesia Zhurakhivska ◽

Iryna Hubytska ◽

Roksolana Konechna

Keyword(s):

Chemical Composition ◽

Medicinal Plant ◽

Raw Materials ◽

Folk Medicine ◽

Medical Application ◽

Biologically Active ◽

Raw Material ◽

Sources Of Information ◽

Scientific Publications ◽

Plant Raw Materials

The object of analytical study is the medicinal plant Pulsatilla alba. This species is rare, the stocks of herbal raw materials are limited, and there are no Pulsatilla alba-based medicines on the Ukrainian market. The aim of study was to analyze and summarize data on the range, content of biologically active compounds and the spectrum of use in pharmacy and medicine Pulsatilla alba. Materials and methods. Literary and electronic sources of information on the distribution, chemical composition and pharmacological activity of Pulsatilla alba. Results. Pulsatilla alba is a plant of the Ranunculaceae family, characterized by a high content of biologically active organic compounds, namely organic acids, traces of alkaloids, vitamins, resinous and tannins, about 20 different macro-and micronutrients, essential oils, γ-lactones, triterpenoids, sterols, chelidonic acid, coumarins, as well as giving it protection status make it an interesting object for research. Analysis of scientific publications revealed that plants of the family Ranunculaceae, in particular, Pulsatilla alba contain a significant amount of biologically active substances, have numerous pharmacological activities, have long been used in folk medicine, and is a promising raw material for the production of phytopreparations. The volume of processing of medicinal plant raw materials in Ukraine in one year is from 5 to 6 thousand tons, the amount of raw materials for export reaches more than 3 thousand tons per year. About 1,000 tons of raw materials consumed in Ukraine are imported and 1,500 tons are domestically produced. Conclusions. Therefore, as populations of rare low-competitive species of the Ranunculaceae family are particularly endangered, displaced by tree, shrub and highly competitive trivial violent herbaceous species due to the widespread use of Pulsatilla alba in folk medicine as an antitumor, hypnotic, hypnotic, antifungal, antifungal research which should be continued

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IDENTIFICATION OF PERMISSIBLE AREAS OF PREPARATION OF MEDICINAL VEGETABLE RAW MATERIALS NEAR TRANSPORT LINES

chemistry of plant raw material ◽

10.14258/jcprm.2020047609 ◽

2020 ◽

pp. 179-186

Author(s):

Nina Alekseyevna Dyakova ◽

Aleksey Ivanovich Slivkin ◽

Yelena Yevgen'yevna Chupandina ◽

Sergey Petrovich Gaponov

Keyword(s):

Medicinal Plant ◽

Raw Materials ◽

Steppe Zone ◽

Biologically Active ◽

Raw Material ◽

Traffic Load ◽

Dust Particles ◽

Forest Steppe ◽

Plant Raw Materials ◽

Vegetable Raw Materials

The purpose of the work is to study the permissible distance for the collection of medicinal plant raw materials near transport highways of different degrees of loading. The study was carried out in the Voronezh region on the example of eight different types of medicinal vegetable raw materials (Herring grass bitter, avian mountain grass, five-foot desert grass, plain thousand-year-old grass, double-ground nettle leaves, large planter leaves, common pajma flowers, core lip flowers) Collected in time of procurement along and at different distance from roads and railways of different degree of load in different natural zones, regulated by normative documentation. In the analyzed samples, the content of standardized biologically active substances, as well as heavy metals, pesticides, radionuclides, was previously estimated and full compliance with pharmacopoeia requirements was shown. In this work, the analysis was carried out on the level of ash insoluble in hydrochloric acid in the medicinal plant raw material, which makes it possible to estimate contamination of the raw material with dust particles. On the basis of the obtained data using the mathematical simulation method, the permissible distances from the transport lines, which can be recommended for the collection of safe medicinal plant raw materials, have been identified: Distance from major roads and highways loaded by road in forest natural zone conditions – at least 230 m, in forest steppe zone conditions – at least 300 m, in steppe zone conditions devoid of wood and shrub vegetation, – Not less than 660 m, near non-high-speed roads characterized by low traffic load – not less than 160 m, near railway lines – not less than 130 m. The obtained results can be recommended for safe collection of medicinal vegetable raw materials.

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TECHNOLOGY FOR OBTAINING PECTIN CONCENTRATE FROM ROSEHIP FRUITS

Farmaciâ Kazahstana ◽

10.53511/pharmkaz.2021.40.42.023 ◽

2021 ◽

pp. 87-90

Author(s):

М.Ж. Кизатова ◽

Д.А. Абдуллаева

Keyword(s):

Medicinal Plant ◽

Raw Materials ◽

Raw Material ◽

Plant Raw Materials ◽

Plant Raw Material ◽

Pectin Substances

Статья посвящена важности пектиновых веществ, а также расширению сферы использования лекарственного растительного сырья. В качестве лекарственного растительного сырья представлены технологии получения пектинового экстракта из плодов шиповника, которые встречаются на территории Казахстана 25 видов. Применение пектина в медицине. The article is devoted to the importance of pectin substances, as well as to the expansion of the use of medicinal plant raw materials. As a medicinal plant raw material, technologies for obtaining pectin extract from rosehip fruits, which are found in 25 species on the territory of Kazakhstan, are presented. The use of pectin in medicine

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Comparative Histochemical analysis of above-ground parts of Filipendula vulgaris and Filipendula ulmaria growing in Central Kazakhstan

Research Journal of Pharmacy and Technology ◽

10.52711/0974-360x.2021.00845 ◽

2021 ◽

pp. 4863-4867

Author(s):

Yerbolat Tulebayev A. ◽

Margarita Ishmuratova Yu. ◽

Irina Losseva V. ◽

Wirginia Kukuła-Koch ◽

Ewa Poleszak ◽

...

Keyword(s):

Secondary Metabolites ◽

Raw Materials ◽

Sesquiterpene Lactones ◽

Biologically Active ◽

Histochemical Analysis ◽

Filipendula Ulmaria ◽

Plant Raw Materials ◽

Related Substances ◽

Histochemical Tests ◽

The Republic

The histochemical analysis of medicinal plants and raw materials makes it possible to establish the presence of certain groups of active and related substances or products of their metabolism, as well as to study their localization in tissues. The article presents the results of histochemical analysis of leaves, flowers, petioles and stems of Filipendula vulgaris and Filipendula ulmaria. These types of plant are used in traditional medicine as an anti-inflammatory, antipyretic and bactericidal agent. Our research objective - to determine the peculiarities of the localization features of individual groups of secondary metabolites in the aerial part of meadowsweet and meadowsweet growing in the territory of Central Kazakhstan at the microscopic level. Materials and Methods. Transverse sections of petioles, stem and whole flower; transverse and superficial sections of leaves of Filipendula vulgaris and Filipendula ulmaria were fixed in Strauss-Fleming solution, after which histochemical reactions were carried out to locate and identify essential oils, phenolic acids, flavonoids, sesquiterpene lactones, polysaccharides and alkaloids. The study of microscopic signs, as well as histochemical tests were carried out according to the methods of the State Pharmacopoeia of the Republic of Kazakhstan using a light microscope Biomed-4. Results and Discussion. The localization of biologically active substances in the studied types of plant raw materials was determined by histochemical methods using light microscopy. The presence of phenolic compounds, flavonoids, traces of essential oil, alkaloids and sesquiterpene lactones was established. The absence of polysaccharides in the investigated micropreparations was established. Conclusions. For the first time, the localization of secondary metabolites in the tissues of Filipendula vulgaris and Filipendula ulmaria was studied by histochemical tests. The results of histochemical studies can be used to confirm the authenticity, identification and standardization of the aerial parts of Filipendula vulgaris and Filipendula ulmaria.

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The Heavy Metals in the System "Soil as a Wild-growing Medicinal Plant" on the Example of Tanacetum Vulgare L

Ecology and Industry of Russia ◽

10.18412/1816-0395-2020-7-37-41 ◽

2020 ◽

Vol 24 (7) ◽

pp. 37-41

Author(s):

G.G. Buskunova ◽

R.F. Khasanova ◽

I.N. Semenova ◽

G.R. Ilbulova

Keyword(s):

Heavy Metals ◽

Medicinal Plant ◽

Raw Materials ◽

Tanacetum Vulgare ◽

Plant Raw Materials ◽

Aerial Parts ◽

Republic Of Bashkortostan ◽

Mobile Forms ◽

Copper Manganese ◽

The Republic

The features of the accumulation of heavy metals in medicinal plant raw materials Tanacetum vulgare L. in the conditions of the Trans-Urals region of the Republic of Bashkortostan are discussed. The variation-statistical indices of the content of heavy metals in soils and in plants are calculated. Soils and plants have high coefficients of heavy metals variation, with the exception of manganese in the soil, which is characterized by moderate variability. An increased level of heavy metals mobile forms, such as Cu, Zn, Mn, Fe, Pb, Cd, has been detected in all soil samples. All selected samples had an elevated level of mobile forms. According to the degree of contamination, the studied soils were classified as permissible. In tansy plants, the concentration of trace elements-biophiles exceeded the norm in Fe 1.7–6.24, in Cd 1.3–1.7 times, and the concentrations of Cu, Zn, Mn, Pb in the aboveground and underground parts of the species remained within the normal range. It is revealed that the root system of Tanacetum vulgare L. contains higher values of the studied elements than the aerial parts. According to the intensity of absorption, the elements are arranged in the following sequence: Zn → Cd → Cu → Fe → Mn → Pb. According to the coefficient of biological accumulation in tansy, ordinary zinc and iron belong to the elements of weak accumulation, copper, manganese, lead, cadmium –to the elements of weak capture.

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Medicinal flora of the Middle Urals – a prospective source of obtaining medicines

Drug development & registration ◽

10.33380/2305-2066-2021-10-4(1)-32-36 ◽

2021 ◽

Vol 10 (4) ◽

pp. 32-36

Author(s):

A. Yu. Turyshev ◽

V. D. Belonogova ◽

A. A. Orlova ◽

K. O. Sidorov ◽

A. Yu. Skornyakova

Keyword(s):

Medicinal Plants ◽

Medicinal Plant ◽

Quantitative Assessment ◽

Raw Materials ◽

The State ◽

Raw Material ◽

Middle Urals ◽

The Middle Urals ◽

Plant Raw Materials ◽

Medicinal Flora

Introduction. Medicinal plant raw materials are one of the most important sources of herbal remedies used both for the prevention and treatment of a number of diseases [1, 2]. Even with the development of modern science and chemistry, medicinal plant raw materials are widely used in both folk and official medicine. The advantage of medicinal plants is their wide range of biological activity, low toxicity and the possibility of long-term use without significant side effects. Human economic activity has a noticeable negative effect on the condition of wild-growing plants: their stocks are decreasing, and some species disappear altogether. Today, given the high level of development of industry and agriculture, the procurement of raw materials for wild medicinal plants is not always possible. Information on the quantitative assessment of the raw material base of wild medicinal plants in the Middle Urals, the content of biologically active substances in medicinal plant raw materials is partially outdated, which determines the need for their systemic resource study and chemical-pharmacognostic study.Aim. Comprehensive assessment of the state of populations of wild medicinal plants in the Middle Urals.Materials and methods. Determination of stocks of raw materials of the studied species of medicinal plants was carried out on specific thickets according to the generally accepted method. The authenticity of the raw materials was established by a macroscopic method when collecting raw material samples. In the course of the study, samples of medicinal plant materials of 5 types were prepared. The determination and assessment of the main indicators of the good quality of medicinal plant raw materials (the content of active and extractive substances, moisture in the mass upon drying, total ash and ash insoluble in a 10% solution of hydrochloric acid) was carried out according to the methods and requirements of the State Pharmacopoeia of the Russian Federation XIV edition. In the raw materials Artemisiae absinthii herba and Leonuri herba, the amount of extractives was determined by the gravimetric method. The quantitative assessment of the content of essential oil in the samples of Origani vulgaris herba and Tanaceti vulgaris flores was carried out by the method of hydrodistillation. To determine the quantitative content of the sum of flavonoids in Hyperici herba, Artemisiae absinthii herba, Leonuri herba and the sum of flavonoids and phenolcarboxylic acids in Tanaceti vulgaris flores, a spectrophotometric method was used.Results and discussion. In the course of resource and phytochemical studies of representatives of the medicinal flora of the Middle Urals, a comprehensive assessment of the state of populations of wild medicinal plants – sources of medicinal plant raw materials (Origani vulgaris herba, Hyperici herba, Tanaceti vulgaris flores, Artemisiae absinthii herba and Leonuri herba) was carried out. The results are included in the electronic inventory of wild medicinal plants of the Middle Urals.Conclusion. The conducted complex of studies will allow updating information about the medicinal flora of the Middle Urals in order to use raw materials for the creation of medicines.

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QUALITY AND NUTRITIONAL VALUE OF FREEZED SEA BUCKTHORN POWDER

Innovations and Food Safety ◽

10.31677/2072-6724-2021-32-2-7-14 ◽

2021 ◽

pp. 7-14

Author(s):

O. M. Burmistrova ◽

E. A. Burmistrov ◽

N. L. Naumova

Keyword(s):

Nutritional Value ◽

Raw Materials ◽

Food Additives ◽

Sea Buckthorn ◽

Biologically Active ◽

Raw Material ◽

Test Material ◽

Plant Raw Materials ◽

Organoleptic Characteristics ◽

Unique Trace

The use of phytopowders as food additives allows you to create highly nutritious mixtures with a pronounced taste and aroma of fresh fruits and berries. Fruit and berry powders are already used in the production of jelly, fruit drinks, drinks, juices and sauces based on domestic plant raw materials with a high proportion of biologically active substances. The most important phytonutrients of sea buckthorn fruits (Hippophae rhamnoides L.) are carotenoids, flavonoids, anthocyanins, sugars, organic and amino acids, tannins and pectin substances, phospholipids, macro- and microelements. The aim of the research was to study the quality and nutritional value of freezedried sea buckthorn powder. Sublimated sea buckthorn was the object of study (TU 10.39.25-007-0111115841-2018) manufactured by IP A.N. Mazurina (Russia, Kaluga region, Borovsky district, Borovsk). The quality of packaging and labeling, as well as organoleptic characteristics, nutritional value and mineral composition of raw materials have been studied. It was determined that the marking of sublimated sea buckthorn does not comply with the regulated requirements of GOST R 51074-2003 and TR CU 022/2011. Organoleptic characteristics of phytopowder are identified as characteristic of this type of raw material. The actual protein and fat content of the test material does not correspond to the levels stated by the manufacturer. The studied raw materials are distinguished by a variety of chemical composition, namely, the content of protein, carotenoids, vitamins E and A, lipids, dietary fiber, unique trace elements – Al, Co, Cr, Cu, Fe, Li, Mn, Ni, Ti, Zn.

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Comparative study of the elemental composition in raw materials of plants of genus Geum L.

Farmatsevtychnyi zhurnal ◽

10.32352/0367-3057.2.21.07 ◽

2021 ◽

pp. 70-77

Author(s):

С. А. Козира ◽

Т. М. Гонтова ◽

С. І. Степанова ◽

В. П. Гапоненко ◽

В. В. Машталер ◽

...

Keyword(s):

Medicinal Plants ◽

Comparative Study ◽

Atomic Absorption ◽

Elemental Composition ◽

Raw Materials ◽

Biologically Active ◽

Raw Material ◽

Material Base ◽

Plant Raw Materials ◽

Microelement Composition

Among the relevant for the modern pharmacy problems, there is a need for the rational complex use of known medicinal plants, as well as the search for new sources of natural biologically active compounds in order to expand the list of official medicinal plants and raw material base. Species of genus Geum L. contain a number of biological active substances and are promising sources of raw materials for the production of antimicrobial, astringent, anti-inflammatory, and hemostatic medicines. Pharmacological activity of these plants results from their multi-component chemical composition, including tannins, flavonoids, macro- and microelements and other compounds. The aim of thе study was to compare the elemental composition of herb and rhizomes with roots of G. urbanum L., G. aleppicum Jacq. and G. rivale L. of Ukrainian flora. The objects of the study were the samples of herb and rhizome with roots of G. urbanum L., G. aleppicum Jacq. and G. rivale L. (dried raw materials) which were collected in the Kharkiv region, Ruski Tishki village, in June-August 2018–2019. The determination of the qualitative composition and quantitative content of elements was carried out by atomic absorption spectroscopy with atomization in an air-acetylene flame using a spectrometer CAS 120 («Selmi», Sumy, Ukraine). In the studied samples, 19 elements were determined, including 5 macroelements and 14 microelements. The data about accumulation of elements in investigated herb of G. urbanum L., G. aleppicum Jacq., G. rivale L. can be arranged in descending order as follows: K > Ca > Si > Mg > P > Fe > Al > Na > Sr > Zn, and in rhizomes with roots as follows – K > Si > Ca > Mg > Fe > P > Al > Na > Sr > Zn. The content of toxic elements such as cobalt, cadmium, arsenic, and mercury was within the permissible limits for plant raw materials and food. For the first time, a comparative study of the macro- and microelement composition in herb and rhizomes with roots of G. urbanum L., G. aleppicum Jacq. and G. rivale L. has been carried out. Using the method of atomic absorption spectral analysis, 19 elements have been identified and their content has been determined, among which К, Ca, Mg, Si, P, Fe, Al, Na, Mn, Zn predominantly accumulate.

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