PHYTOCHEMICAL, PHARMACOLOGICAL SCREENING AND IMPORTANCE OF MARSDENIA TENACISSIMA: A REVIEW

INDIAN DRUGS ◽  
2021 ◽  
Vol 58 (4) ◽  
pp. 7-22
Author(s):  
Mayur Porwal ◽  
◽  
Arvind Kumar ◽  
Kamal K. Maheshwari ◽  
Najam A. Khan ◽  
...  
Keyword(s):  
Heart Disease ◽  
Skin Disease ◽  
Recent Literature ◽  
Biological Activities ◽  
Intermittent Fever ◽  
Pharmacological Activities ◽  
Phytochemical Constituents ◽  
Pharmacological Screening ◽  
Anti Hiv ◽  
Marsdenia Tenacissima

In conventional methods of medication, Marsdenia tenacissima (family: Apocynaceae) is used in the treatment of scurvy, urinary diseases, arthritis, heart disease, skin disease, pruritus, vomiting and intermittent fever. Estimation of biological activities confirmed that M. tenacissima plant shows antipyretic, antioxidant, anticancer and anti-HIV activities. This assessment presents the phytochemical constituents, traditional importance and pharmacological activities accounted for the plant in recent literature and it will be supportive to explore incisive information about M. tenacissima for the researchers.

scholarly journals Synthesis and Biological Activities of Some Pyrimidine Derivatives: A Review

2020 ◽  
Vol 36 (6) ◽  
pp. 1001-1015
Author(s):  
Nadia Ali Ahmed Elkanzi
Keyword(s):  
Nitrogen Atom ◽  
Medicinal Chemistry ◽  
Biological Activities ◽  
Heterocyclic Ring ◽  
Ring System ◽  
Pyrimidine Derivatives ◽  
Pharmacological Activities ◽  
Cardiovascular Agents ◽  
Anti Hiv ◽  
Biological And Pharmacological Activities

Nitrogen containing synthetically and biologically important heterocyclic ring system namely pyrimidine possess both biological and pharmacological activities, and defend as aromatic six heterocyclic with 1and 3 nitrogen atom in ring. Preparation of pyrimidine via different methods offer its importance in fields of medicinal chemistry and Chemistry. Pyrimidines and their derivatives act as anti-inflammatory, anti-malaria, anti-tumor, cardiovascular agents, anti-neoplastic, anti-tubercular, anti- HIV, diuretic ,anti-viral, anti-microbial, ,analgesic .This review give light up on biological and pharmacological activities of pyrimidine nucleus.

scholarly journals Rivea Hypocrateriformis (Desr.) Choisy: A Review of its Ethnomedicinal Uses, Phytochemistry and Biological Activities

2021 ◽  
Author(s):  
Mohammad Mukim ◽  
Atul Kabra ◽  
Christophe Hano ◽  
Samantha Drouet ◽  
Duangjai Tungmunnithum ◽  
...  
Keyword(s):  
Sri Lanka ◽  
Organic Compounds ◽  
Skin Disease ◽  
Biological Activities ◽  
Snake Bite ◽  
Pharmacological Activities ◽  
Traditional Uses ◽  
Phytochemical Investigation ◽  
Long Time ◽  
Ethnomedicinal Uses

Rivea hypocrateriformis (Desr.) Choisy is a robust woody climbing shrub of the genus Rivea which is found in India, Nepal, Sri Lanka, Pakistan, Bangladesh, Myanmar and Thailand. R. hypocrateriformis is a promising medicinal herb with enormous helpful and wellbeing advancing impacts. R. hypocrateriformis has been utilized as a customary medication for a long time to treat rheumatic pain, fever, urogenital problem, snake bite, cough, piles, malaria, and skin disease. Apart from the traditional uses its leaves and young shoots are cooked and eaten as a vegetable and for preparation of bread with millet flour. This review comprehensively summarizes the up-to-date information on the botanical characterization, distribution, traditional uses, phytochemistry, pharmacology and toxicity study of R. hypocrateriformis. Phytochemical investigation has been revealed that alkaloids, glycosides, coumarins, flavonoids, xanthones, stilbenes, and other organic compounds are contained in R. hypocrateriformis. Crude extracts and isolated compounds have exhibited numerous pharmacological activities such as anovulatory effect, antifertility activity, antiarthritic, antimicrobial, anticancer, antioxidant, hepatoprotective, antilithiatic, antimitotic. R. hypocrateriformis is a promising restorative spice with monstrous remedial and wellbeing advancing impacts. Along these lines, further investigations on the bioactive mixtures and systems of R. hypocrateriformis are justified. Extra clinical and toxicological examinations are expected to assess its wellbeing.

scholarly journals PHYTOCHEMICAL CONSTITUENTS AND PHARMACOLOGICAL ACTIVITIES OF Kigelia africana AND Mansoa alliacea - A COMPREHENSIVE REVIEW

2018 ◽  
Vol 11 ◽  
Author(s):  
Sowmyalakshmi Venkataraman ◽  
Gunda Srilakshmi
Keyword(s):  
Rural Areas ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Reproductive Organ ◽  
Human Beings ◽  
Pharmacological Activities ◽  
Phytochemical Constituents ◽  
Athlete’S Foot ◽  
Collective Information

Context: The focus of the present review is to compile the different phytochemical constituents and pharmacological activities of bignoniaceous plants, namely Kigelia africana and Mansoa alliacea. Objective: Medicinal plants are routinely used in clinical practice for the treatment of various diseases of human beings over thousands of years across the world. In rural areas of the developing countries, they are still used in practice due to the easy availability of the medication. The main objective of this work is to explore the phytochemical studies and biological activities of plants belonging to Bignoniaceae family. Methods: The present study also discusses about the different phytochemical constituents of K. africana and M. alliacea that were isolated and characterized using various analytical methods. Different extracts of these plants were subjected to different in vitro anticancer, analgesic, antimicrobial, and antimalarial activities using earlier reported methods were also discussed. Results: K. africana is commonly referred to as sausage or cucumber tree due to its huge sausage or cucumber-like fruit. These plants find application as traditional medicine for treating several ailments such as malignant tumor, ulcer, aging, and malaria among others. It is conjointly used for the treatment of reproductive organ infections, renal ailments, dizziness, epilepsy, sickle cell disease, depression, metabolism disorders, skin grievance, leprosy, impetigo, helminthic infections, athlete’s foot, tumors, etc. These plant extracts have also been used as a cosmetic by enhancing the collagen action and thus exhibit antiaging properties. Conclusion: The present study attempts to provide collective information on various phytochemical constituents and pharmacological actions of K. africana and M. alliacea belonging to Bignoniaceae. This review in its present form is believed to help the researchers to provide adequate information about the chemical constituents and biological uses of these plants.

Benzofuran: A Key Heterocycle - Ring Closure And Beyond

2020 ◽  
Vol 17 (3) ◽  
pp. 224-276
Author(s):  
Andiappan Lavanya ◽  
Kilambi Narasimhan ◽  
Vediappen Padmini
Keyword(s):  
Biological Activities ◽  
Extraction Process ◽  
Ring Closure ◽  
Pharmacological Activities ◽  
Naturally Occurring ◽  
Synthetic Materials ◽  
Privileged Scaffold ◽  
Medicinal Properties ◽  
Anti Inflammatory ◽  
Anti Hiv

: The benzofuranyl motif present in compounds exhibits various medicinal properties and non-drug applications. These derivatives are naturally occurring compounds or synthetic materials, which cover a broad spectrum of pharmacological activities like anti-inflammatory, anti-diabetic, anti- depressant, anti-HIV, anti-microbial, anti-proliferative, anti-convulsant, cytotoxic, analgesic, etc. Few of the commercially interesting compounds from this class are, ailanthoidol (anti-inflammatory), amiodarone, dronedarone, celivarone (anti-arrhythmic), bufuralol (muscular airways relaxant), morphine, 5-(2-aminopropyl)benzofuran; 5-APB, 6-(2-aminopropyl)benzofuran; 6-APB (CNS), rifampicin (antibiotic), etc., whereas, some of the non-drug applications are in perfumery industry (bergapten) and as tannin activators in sunscreen preparations (psoralen, 8-methoxypsoralen, and angelicin). Considering these interesting biological activities and commercial utilities, a review on the synthetic aspects of this privileged scaffold was attempted. For the benefit of natural product-based drug discovery, available sources of these derivatives, extraction process and reported biological activities have also been outlined in this review.

scholarly journals Biological Activities and Phytochemical Constituents of Trailing Daisy Trilobata: A Review

2019 ◽  
Vol 9 (4-s) ◽  
pp. 888-892
Author(s):  
K Sai Prasanna ◽  
G Jyothi Reddy ◽  
M Kiran ◽  
K Thyaga Raju
Keyword(s):  
Skin Diseases ◽  
Biological Activities ◽  
Pharmacological Activities ◽  
Traditional System ◽  
Wedelia Trilobata ◽  
Anti Oxidant ◽  
Phytochemical Constituents ◽  
Anti Inflammatory ◽  
Anti Fungal ◽  
Natural Medicines

The traditional system of medicinal plants have been found to possess significant anti-inflammatory, antibacterial, anti-fungal, anti-diabetic, analgesic properties etc. Plant-derived drugs are used to cure mental illness, skin diseases, tuberculosis, diabetes, jaundice, hypertension, and cancer. Wedelia Trilobata belongs to family Asteraceae. Leaf, stem, and flower of Wedelia trilobata show anti-microbial, anti-oxidant and anti-inflammatory activity, analgesic activity. Phytochemical screening of the extract has been reported to show the presence of tannins, cardiac glycosides, flavonoids, terpenoids, phenols, saponins, and coumarins. Wedelia Trilobata is also used in reproductive problems, amenorrhea, chest cold, dry cough, and fever. The present review aims to the study was phytoconstituents, biological and pharmacological activities of Wedelia trilobata. This study suggested a possible use of Wedelia trilobata as a source of natural medicines as an anti-inflammatory, anti-oxidant, anti-microbial, hepatoprotective, antidiabetic agents. Keywords: Wedelia Trilobata, Trialing daisy trilobata, Complaya trilobata(L), Sphagneticola Trilobata, pharmacological review.

scholarly journals A review on Lantana rhodesiensis Moldenke: traditional uses, phytochemical constituents and pharmacological activities

2017 ◽  
Vol 9 (1) ◽  
pp. 01 ◽  
Author(s):  
BANGOU Mindiédiba Jean ◽  
MEDA Roland Nâg-Tiero ◽  
KIENDREBEOGO Martin ◽  
NACOULMA Odile Germaine ◽  
ALMARAZ-ABARCA Norma
Keyword(s):  
Diabetes Mellitus ◽  
Chemical Composition ◽  
Biological Activities ◽  
Folk Medicine ◽  
Literature Survey ◽  
Parasitic Diseases ◽  
Pharmacological Activities ◽  
Traditional Uses ◽  
Whole Plant ◽  
Phytochemical Constituents

<em>Lantana rhodesiensis</em> Moldenke an herbaceous, belonging to the Verbenaceae family is widely used in Africa folk medicine for the treatment of cancer, measles, malaria, smallpox, strength, coughs, fever, rheumatism, body pains, diabetes mellitus arrhythmia, parasitic diseases, arterial hypertension, old diarrhoeas. Many studies have been conducted on the chemical composition of the whole plant of <em>L. rhodesiensis</em> as well as biological activities.  The aim of the present review was to give a detailed literature survey on its traditional uses, phytochemistry and therapeutical properties of <em>L. rhodesiensis</em>.

An Updated Overview on Ethnomedicinal Uses, Phytochemical and Various Pharmacological Evaluations on the Plant Capparis decidua (Forssk.) Edgew.

2020 ◽  
Vol 06 ◽  
Author(s):  
Shalu Pal ◽  
Rupali S. Prasad ◽  
Satyendra K. Prasad ◽  
Ramesh K. Goyal ◽  
Mahaveer Dhobi
Keyword(s):  
Biological Activities ◽  
Indian Subcontinent ◽  
In Vitro Cytotoxicity ◽  
Intermittent Fever ◽  
Pharmacological Activities ◽  
Cytotoxicity Activity ◽  
Pharmacological Significance ◽  
Capparis Decidua ◽  
Anti Fungal

Background: Capparis decidua (Forssk.) Edgew. (Kareel) is a multifunctional perennial woody plant belongs to the family Capparaceae, widely distributed in the hot arid regions of different parts of the world especially in the Indian subcontinent, Africa and Saudi Arabia. Objective: The review aims at presenting updated information with respect to ethnopharmacological relevance and recent findings on phytochemical and biological activities of Capparis decidua. Objective: The review aims at presenting updated information with respect to ethnopharmacological relevance and recent findings on phytochemical and biological activities of Capparis decidua. Method: The literature survey was carried out with the help of various sources such as Scifinder, Pubmed, Scopus, Science Direct, and Google Scholar. Results: Phytochemical review of the plant has revealed the presence of mainly glycosides, alkaloids, flavonoids, terpenoids, volatile oils, fatty acids and steroids that possess immense pharmacological activities. The plant has been used traditionally as an expectorant, carminative, digestive, stimulant, antimicrobial, aphrodisiac, anodyne, anthelmintic and is also useful in ailments like cough, dropsy, dyspepsia, intermittent fever, asthma, intestinal worms, constipation, lumbago, odontalgia, amenorrhoea, dysmenorrhoea and cardiac disorders etc. Several pharmacological and biological activities using various parts of the plant have been reported like antidiabetic, antiparasitic, analgesic, hepatoprotective, anti-inflammatory, anti-rheumatic, anti-gout, in-vitro cytotoxicity activity, antihyperlipidemic, anti-atherosclerotic, anti-nephrolithiasis, anti-microbial and anti-fungal. Nutritionally, the fruits of the plant are used for preparing pickle and also in the food preparations since ancient times. Conclusion: Even though the plant has numerous pharmacological properties, there are many secluded pharmacological activities of the plant which still needs to be explored. Considering the importance of the plant in the pharmaceutical and nutritional area, the present review is an attempt to focus on up to date studies performed on the plant C. decidua, mainly concerning the phytochemical and pharmacological significance, which will benefit researchers having an interest in the relevant field.

scholarly journals Medicinal Uses, Phytochemistry and Pharmacological Properties of Elaeodendron transvaalense

Nutrients ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 545
Author(s):  
Alfred Maroyi ◽  
Sebua Semenya
Keyword(s):  
Herbal Medicine ◽  
Southern Africa ◽  
Skin Infections ◽  
Journal Articles ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Phytochemical Compounds ◽  
Phytochemical Constituents ◽  
The University ◽  
Anti Hiv

Elaeodendron transvaalense is a plant species, which is in high demand as a herbal medicine in southern Africa. This study critically reviewed the medicinal applications, phytochemistry and pharmacological activities of E. transvaalense. The literature on medicinal applications, phytochemical, and pharmacological activities of E. transvaalense, was collected from multiple internet sources including Elsevier, Google Scholar, SciFinder, Web of Science, Pubmed, BMC, Science Direct, and Scopus. Complementary information was gathered from pre-electronic sources, such as books, book chapters, theses, scientific reports, and journal articles obtained from the University library. This study revealed that the species is used as herbal medicine in 62.5% of the countries where E. transvaalense is native in southern Africa. It is mainly used as herbal medicine for diarrhoea, menorrhagia, stomach aches, skin infections, inflammations, and rashes. Phytochemical compounds identified from the species, include flavonoids, peltogynoid, phenols, proanthocyanidins, tannin, and triterpenes. Ethnopharmacological research revealed that extracts and phytochemical constituents isolated from E. transvaalense have antibacterial, antifungal, anti-HIV, anti-inflammatory, antioxidant, antiplasmodial, anti-protozoan, anti-pyretic, hypoglycaemic, larvicidal, cytotoxicity, and mutagenic activities. Elaeodendron transvalense should to be subjected to detailed phytochemical, pharmacological, and toxicological evaluations aimed at correlating the medicinal uses of the species with the ethnopharmacological properties of the species.

scholarly journals LANNEA SCHIMPERI: REVIEW OF ITS BOTANY, MEDICINAL USES, PHYTOCHEMISTRY, AND BIOLOGICAL ACTIVITIES

2019 ◽  
pp. 31-36
Author(s):  
ALFRED MAROYI
Keyword(s):  
Cardiac Glycosides ◽  
Web Of Science ◽  
Biological Activities ◽  
Journal Articles ◽  
Tropical Africa ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Phytochemical Compounds ◽  
Phytochemical Constituents ◽  
The University

Lannea schimperi is a well-known fruit tree and medicinal plant in tropical Africa. The current study critically reviewed the botany, medicinal uses, phytochemistry, and pharmacological activities of L. schimperi. Literature on botany, medicinal uses, phytochemical and biological activities of L. schimperi were collected from multiple internet sources including Elsevier, Google Scholar, SciFinder, Web of Science, PubMed, BMC, ScienceDirect, and Scopus. Complementary information was gathered from pre-electronic sources such as books, book chapters, theses, scientific reports, and journal articles obtained from the University Library. This study revealed that the species is used as a source of fiber, edible fruits, and herbal medicine. Phytochemical compounds identified from the species include cyclohexenones, cardanols, alkaloids, anthocyanins, anthracene glycosides, carbohydrates, cardiac glycosides, carotenoids, condensed tannins, coumarins, flavonoids, phenolic glycosides, phenols, polyoses, polyuronoids, reducing sugars, saponins, steroids, tannins, triterpenoids, and volatile compounds. Pharmacological research revealed that extracts and phytochemical constituents isolated from L. schimperi have anesthetic, antibacterial, antifungal, anticoccidial, anti-inflammatory, antinociceptive, antioxidant, anti-trypanosoma, antiulcerogenic, cytotoxicity, and toxicity activities. L. schimperi should be subjected to detailed phytochemical, pharmacological, and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities of the species.

scholarly journals Arylnaphthalene lactones: structures and pharmacological potentials

2021 ◽  
Author(s):  
Soyoung Park ◽  
Seungsu Kim ◽  
Dongyun Shin
Keyword(s):  
Drug Discovery ◽  
Medicinal Plants ◽  
Biological Activities ◽  
Structural Diversity ◽  
Structural Features ◽  
Type I ◽  
Type Ii ◽  
Pharmacological Activities ◽  
Naturally Occurring ◽  
Anti Hiv

AbstractNatural arylnaphthalene lactones are representative lignans that are found in various dietary and medicinal plants. Their unique structural features and significant pharmacological activity have attracted considerable attention from both synthetic and medicinal chemists. Owing to their unique structural features such as relative rigid tetracyclic skeleton, structural diversity of more than five substituents, and no chiral center, arylnaphthalene lactones are recognized as a valuable scaffold for drug discovery, in addition to their significant pharmacological activities. This review covers the structures and isolation of all naturally occurring arylnaphthalene lactone congeners reported. Based on the aryl substituents, they were categorized as Type I and Type II and further classified according to the oxidation state of the ring and glycosylation level. Special attention has been paid to natural arylnaphthalene lactones owing to their broad spectrum of biological activities such as cytotoxic, antiplatelet, antiviral, anti-HIV, antifungal, neuroprotective, and anti-inflammatory properties. All the products were reorganized based on their biological activities, and selected data are presented.

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