scholarly journals Establishing of the mono- and polyinvasion impact on some morpho-functional indices in wild boars

2021 ◽  
Author(s):  
Stefan Rusu ◽  

In the paper is described the mono- and poly-invasions impact on some morpho-functional indices in wild boars. So, in result of the investigation of hematological indices in uninfested mono- and poly-parasitized wild boars, it was established that both the indices of hemoglobin content, of hematocrit, erythrocyte’s number, thrombosis time and ESR (erythrocyte sedimentation rate) vary and are more increased in the I group with uninfested wild boars compared to mono - and poly-parasitized ones. It has been established that at infested boars with S. papillosus from the I group, and in those infested with D. lanceolatum from the II group there is a decrease of hemostatic indices, but their maximum decrease is highlighted in the IV group with wild boars infested with Dicrocoelium lanceolatum, Strongyloides papillosus, Metastrongylus elongatus and Eimeria debliecki. This decrease is due to eliminated exotoxins by parasites, which contain anticoagulants and hemolyzers and which neutralize the fibrinogen, thrombin, Ca+ ions and vitamin K properties from the body.

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Marwan Al-Nimer ◽  
Rawa Ratha ◽  
Taha Mahwi

Objectives. Tetrahydrobiopterin (BH4) pathway that included generation of neopterin (Neop), biopterin (Biop), and nitric oxide (NO) is altered in type 2 diabetes (T2D). The aim of this study was to assess the biomarkers of BH4 pathway in noninfected DFUs and to relate these levels to the variables of diabetes as well as to the hematological indices. Methods. We performed a cross-sectional investigating study in a Kurdish people including 30 healthy subjects (group I), 66 T2D patients (group II), and 57 DFUs patients (group III). Hematological indices including red cell distribution width (RDW), mean platelet volume (MPV), and platelet distribution width (PDW) were determined by Coulter hematological analysis. Serum BH4 markers including NO, Neop, and Biop were determined by using an enzyme-linked immunosorbent assay (ELISA) technology. The relationship between BH4 markers with glycemic and hematological indices was assessed by Spearman’s correlation and multivariable regression analysis. Results. Neop was significantly increased while PDW was significantly decreased in group III compared with group II patients. Nitric oxide was found to be inversely correlated with age (r=−0.382), duration of diabetes (r=−0.264), mean arterial blood pressure (r=−0.532), body mass index (r=−0.321), RDW (r=−0.322), and PDW (r=−0.284) in group III patients. Circulating Neop and Biop significantly correlated with RDW and erythrocyte sedimentation rate. Multivariable regression analysis revealed that serum Neop predicted the DFUs in 92.5% of group III patients. Conclusion. Tetrahydrobiopterin biomarkers are predictors of DFUs and the significant correlation of neopterin with red distribution width and erythrocyte sedimentation rate indicating the role of neopterin in the vascular and inflammation concerns of noninfected DFUs.


2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Farhad Salehzadeh ◽  
Ahmadvand Noshin ◽  
Sepideh Jahangiri

Background. Erythrocyte sedimentation rate (ESR) is a valuable laboratory tool in evaluation of infectious, inflammatory, and malignant diseases. Red blood cells in outside from the body precipitate due to their higher density than the plasma. In this study we discuss the IVIG effect on ESR in different diseases and different ages.Methods and Materials. Fifty patients under 12 years old who had indication to receive IVIG enrolled in this study. Total dose of IVIG was 2 gr/kg (400 mg/kg in five days or 2 gr/kg in single dose). ESR before infusion of IVIG and within 24 hours after administration of the last dose of IVIG was checked.Results. 23 (46%) patients were males and 27 (54%) were females. The mean of ESR before IVIG was31.8±29.04and after IVIG it was47.2±36.9; this difference was meaningful(P=0.05). Results of ESR changes in different age groups, 6 patients less than 28 days, 13 patients from 1 month to 1 year, 20 patients from 1 to 6 years old, and 11 patients from 6 to 12 years have been meaningful (P=0.001,P=0.025, andP=0.006, resp.).Conclusion. In patients who are receiving IVIG as a therapy, ESR increased falsely (noninflammatory rising); therefore use of ESR for monitoring of response to treatment may be unreliable. Although these results do not apply to neonatal group, we suggest that, in patients who received IVIG, interpretation of ESR should be used cautiously on followup.


2021 ◽  
Vol 25 (1(97)) ◽  
pp. 82-88
Author(s):  
O. Radchenko ◽  
O. Fedyk

Patients with chronic obstructive pulmonary disease (COPD) in combination with anemia of chronic disease (ACD), are of particular interest to both scientific and practical health care. The purpose of the work - to study the activity of systemic inflammation.Material and methods. The results of the examination of 475 patients with exacerbation of COPD were analyzed, which were divided into two groups: group I - 155 people (61,3% men and 38,7% women) with ACD; group II - 320 patients (46,9% of men and 53,1% of women) without the anemic syndrome. Determination of the activity of the inflammatory process was performed by hemocytogram, serum markers of inflammation and integrated hematological indices. The results of the study. It was found that COPD in combination with ACD was accompanied by activation of the inflammatory process (erythrocyte sedimentation rate, segmented neutrophils content) and suppression of lymphocyte-monocyte inflammation, significantly higher integral hematological indices (leukocyte shift index; ratio of leukocytes, non-segmented neutrophils and all neutrophils to the erythrocyte sedimentation rate; the ratio of neutrophils to lymphocytes and the integrated index of inflammation), which increased with the deepening of the anemic syndrome, increasing patients age and was more pronounced in women. Activation of inflammation was associated with deterioration of bronchial patency according velocity parameters (Tiffno index, mean and peak volumetric velocities, maximal volumetric velocities by 25% and 75% of the forced ungs vital capacity). Anemic syndrome was also associated with higher levels of C-reactive protein (p>0,05), general fibrinogen (p<0,05) and seromucoids (p>0,05), the content of which varied in parallel with the leukocyte shift index. Conclusion. Anemic syndrome, as a manifestation of persistent systemic inflammation, worsens the course of a chronic obstructive pulmonary disease through affecting the respiratory function and the inflammatory process activation.


2020 ◽  
Vol 99 (1) ◽  
pp. 125-128
Author(s):  
L. M. Karamova ◽  
Natalya V. Vlasova ◽  
L. G. Gizatullina ◽  
L. M. Masyagutova

Introduction. Medical workers in the process of labor are exposed to a complex of adverse factors: neuro-emotional, physical stress of a chemical, physical and biological nature. A long stay in a hospital environment with medical workers can lead to the formation of various diseases of microbiological etiology or the carriage of pathogenic and conditionally pathogenic flora and the development of dysbiosis. Objective. Give hematological and bacteriological characteristics of the health status of medical workers. Material and methods. The results of laboratory studies of blood and mucous membranes of the upper respiratory tract of medical workers performed during the performing occupational medical examinations are analyzed. Results. Hematological indices were found to be characterized by an increased hemoglobin content in one-fourth of the examined workers, as well as lymphocytosis, eosinophilia, cholesterolemia. The microflora of the mucosa of the upper respiratory tract is mainly represented by Staphylococcus aureus, Candida albicans, Streptococcus pyogenes in 65.2% of the workers; the remaining 34.8% were revealed to have a resident microflora. With the experience of work, the frequency of insemination increases and doubles by 10 years of the work. The structure of microflora is also changing. In the nosological form of occupational morbidity, allergic diseases prevail and account for 60.8%, tuberculosis - 26.0%, and hepatitis - 8,6%. Conclusion. All these changes in the body are the basis of pathogenetic manifestations in the formation of allergic and pathogenic pathologies, which make up to 70.0% of all occupational morbidity.


2020 ◽  
Vol 19 (S2) ◽  
pp. 96-102
Author(s):  
E Grabovskaya ◽  
T Lyalina ◽  
N Tarabrina

Aim. The purpose of the article is to study the impact of low-intensity electromagnetic radiation of quantum and micro-vibration effect on nonspecific adaptive reactions and the blood system of wrestlers. Materials and methods. Athletes of the first category or those having master of sport title with at least a five-year experience aged 18–22 years participated in the study. All participants underwent a course of therapy with low-intensity electromagnetic radiation of quantum and micro-vibration effect. The exposure was performed on a daily basis according to the principle ‘one day – one exposure zone’. The course consisted of 10 procedures. Non-specific adaptive reactions of the body, some morphological indicators of red blood, leukogram, erythrocyte sedimentation rate were determined. Mathematical and statistical processing of the data obtained was carried out. Results. It was revealed that low-intensity electromagnetic radiation of quantum and micro-vibration effect improved and stabilized the blood system and nonspecific adaptive reactions of the body. Conclusion. The course treatment with low-intensity electromagnetic radiation of quantum and micro-vibration effect contributes to the redistribution of nonspecific adaptive reactions of the body with an increase in training reactions, calm and increased activation. An increase in the average concentration of hemoglobin in erythrocytes, a slight decrease in hematocrit, a change in the composition of leukogram, and a decrease in the erythrocyte sedimentation rate were registered.


2020 ◽  
Vol 7 (1) ◽  
pp. 34
Author(s):  
Aini Aini Aini ◽  
Nurmawan Nurmawan ◽  
Jumari Ustiawaty

Tuberculosis is a disease caused by rod-shaped bacteria (basil) with another name Mycrobacterium tuberculosis. Mycrobacterium tuberculosis enters the body then causes inflammation, inflammation and bacterial invasion which then induces liver cells to synthesize acute phase C-reactive protein protein (CRP). CRP will increase sharply after inflammation, as well as the formation of aggregates derived from the acute phase protein hormone which causes an increase in the Erythrocyte sedimentation rate (ESR)). The purpose of this study was to determine the relationship Erytrocyte sedimentation rate (ESR) and levels of C-Reactiv protein (CRP) in tuberculosis (TBC) patients. This research is an analytical descriptive study using cross sectional. Data collectors are done using the Non Random Accidental Sampling technique. The number of respondents in this study were 11 people with tuberculosis. Based on the results of this study it is known that TBC patients with smear negative as much as 7 people (63.6%) and TB patients with positive smear as much as 4 people (36.4%), both in TB patients with negative smear and positive smear both have levels of ESR not normal with an average ESR level in positive smear of 101.3 mm / hour and the average ESR level in smear negative is 20.8 mm / hour. All TBC patients with smear positive CRP levels (not normal) with an average mean value of CRP of 36 mg / L or an average CRP level in TBC smear negative patients of 0.9 mg / L. Based on the Pearson test results between levels of erythrocyte sedimentation rate (ESR) with C-Reactive protein (CRP) in tuberculosis (TBC) patients obtained a value of p <0.01 (0.000 <0.01). This shows a strong relationship between LED and CRP levels in TB patients


Author(s):  
M. Khariv ◽  
B. V. Gutyj ◽  
V. Butsyak ◽  
І. Khariv

<p>The article deals with the results of search of the influence of developed complex liposomal drug on dynamics of hematological parameters of rat organisms under conditions of simulated oxidative stress caused by the use of carbon tetrachloride. Intramuscular injection of 50% tetrachloromethane to rats at a dose of 0.25 ml per 100 g of body weight causes antigenic load on the body and leads to disruption of physiologic level of hematological indices of experimental animal organisms. This indicates the number reduce of red blood cells, hemoglobin content, hemoglobin concentration in erythrocyte, increasing the number of leukocytes, mass of hemoglobin in erythrocyte and increased of color index.</p><p>To normalize the hematological indices of rat organisms for the development of oxidative stress it is advisable to apply the liposomal drug that incorporates contains butafosfan, interferon, milk thistle and vitamins. When using liposomal drug to rats, under conditions of oxidative stress, the normalization of hematological indices comes in blood, namely on 14th day within physiological variables were indicators of the number of erythrocytes of hemoglobin content, white blood cell count and indices of red blood cells compared to controls, indicating a recovery of hematopoietic function of marrow.</p>


Author(s):  
O.M. Radchenko ◽  
O.V. Fedyk ◽  
R.R. Guta

A retrospective analysis of 470 patients with chronic obstructive pulmonary disease and anemia was conducted in order to determine hematological indices. 17 markers of inflammation activity, endogenous intoxication, adaptation, nonspecific and immune reactivity were calculated during this analysis. It was established that the course of chronic obstructive pulmonary disease with anemia was accompanied by a more pronounced inflammation syndrome with a significant increase in stab and segmented neutrophilic granulocytes, an acceleration of the erythrocyte sedimentation rate, and significantly higher integral hematological inflammation indixes (leukocyte shift index, indexes of correlation: -leukocytes to erythrocyte sedimentation rate, -neutrophils to erythrocyte sedimentation rate, -nonsegonuclear neutrophils to erythrocyte sedimentation rate, neutrophils to lymphocytes; inflammation activity index, integrated inflammation index), large endogenous intoxication (neutrophil reactive response index, leukocyte intoxication index), change in adaptation, nonspecific reactivity (decrease in adaptation index, immune reactivity and allergization, and increase in the ratio indices: lymphocytes to monocytes, - lymphocytes to eosinophils) with activation of the phagocytic link of nonspecific protection over cell-humoral. The determination of integral hematological indices is an important, informative and accessible method for assessing the general condition of a patient with chronic obstructive pulmonary disease and anemia.


2012 ◽  
Vol 3 (1) ◽  
pp. 17-19
Author(s):  
MO Faruqe ◽  
MR Alam ◽  
MER Bhuiyan ◽  
M Myenuddin

To evaluate the certain haematobiochemical parameters in different ages of Hubbard Classic broiler birds, the study was performed at Kazi Farms Ltd., Gazipur in collaboration with the Department of Physiology, Bangladesh Agricultural University, Mymensingh for a period of one month (1st to 30th March 2002). On haematobiochemical examination, total erythrocyte count, haemoglobin content, packed cell volume, clotting time, glucose and uric acid concentration were gradually increased with advancement of age of birds. The values of TEC, Hb, PCV, clotting time, glucose and uric acid were recorded at day old birds as average 1.23 ± 0.02 million / cmm, 3.90 ± 0.09 g%, 19.60± 0.24 % , 37.20 ± 1.50 second, 179.20 ± 8.95 mg / dl and 3.72 ± 0.58 mg / dl respectively while the values at day 30 were 2.43 ± 0.07 million / cmm, 7.26 ± 0.16 g%, 28.20 ± 0.58%, 206.40 ± 10.17 second, 271.60 ± 8.56 mg / dl and 6.42 ± 0.65 mg / dl respectively which were found statistically significant (p < 0.01). On the other hand erythrocyte sedimentation rate, cholesterol and urea concentration were gradually decreased where significantly (p < 0.05) higher values (2.80 ± 0.20 mm in 1st hour, 330.40 ± 38.52 mg / dl and 26.42 ± 2.06 mg/ dl respectively) were recorded at day old chicks and lower values (1.80 ± 0.37 mm in 1st hour, 104.20 ± 3.24 mg / dl and 17.00 ± 0.07 mg / dl respectively) were recorded at age of 30 days old of birds. The findings of the present work clearly indicate that age has got influential effect on the body haemopoietic system of the broiler birds as well as haematobiochemical values.


2019 ◽  
Vol 3 (1) ◽  
pp. 14-18 ◽  
Author(s):  
Safia Sultana ◽  
Nabila Afsar ◽  
Mohammed Jawad ◽  
Mohammed Abdul Hannan Hazari

Smoking is one of the leading causes of death worldwide. Smokers have higher risk for coronary heart disease, atherosclerosis, acute myocardial infarction, hypertension, clotting disorders, inflammation, respiratory diseases, cancers, etc. A cigarette smoker is exposed to a number of harmful substances. In this study we hypothesized that smoking causes inflammatory reactions and induces hyperthrombic state in the body which may be reflected in erythrocyte sedimentation rate (ESR), total leucocyte count (TLC), differential leucocyte count (DLC) and platelet count values. The purpose of the study was to study the effects of cigarette smoking on erythrocyte sedimentation rate, total leucocyte count and platelet count in adult male smokers and to compare the results with non-smokers and to establish a relationship between the duration and quantity of smoking with the change in ESR, TLC, DLC and platelet count. A cross sectional study was conducted in the department of Pathology on 86 healthy male subjects (smokers=43 and non-smokers=43). ESR was estimated using Westergrens method. TLC, DLC and platelet counts were estimated using HORIBA Pentra ES60 autoanalyzer. TLC and basophil counts were significantly higher in smokers than in non-smokers (p<0.05). The mean value of ESR was higher among smokers than non-smokers but it was statistically insignificant. Platelets counts showed no significant difference between smokers and non- smokers. No correlation was observed in various blood parameters and smoking (in pack years). We conclude that smoking initiates an inflammatory response as evidenced from raised TLC, monocyte and basophil counts.


Sign in / Sign up

Export Citation Format

Share Document