Preparation and content determination of metoclopramide hydrochloride rectal delivery mucilage

2020 ◽  
Vol 20 (5) ◽  
pp. 389-391
Author(s):  
Weihua JIN ◽  
Botao YU ◽  
Ming ZHANG ◽  
Zhiqiang PU ◽  
Xue LI
Keyword(s):  
Content Determination ◽  
Metoclopramide Hydrochloride ◽  
Rectal Delivery

Determination of readiness for laying based on material moisture, corresponding relative humidity, and water release

2020 ◽  
Vol 62 (10) ◽  
pp. 1033-1040
Author(s):  
Christoph Strangfeld ◽  
Sabine Kruschwitz
Keyword(s):  
Relative Humidity ◽  
Moisture Content ◽  
Embedded Sensors ◽  
Residual Water ◽  
Floor Covering ◽  
Water Release ◽  
Content Determination ◽  
Two Samples ◽  
Moisture Content Determination

Abstract The moisture content of the subfloor has to be determined before installation to avoid damage to the floor covering. Only if readiness for layering is reached, can an installation without damage be expected in all cases. In general, three approaches exist to measure residual water content: determination of moisture content, determination of water release, or determination of the corresponding relative humidity. All three approaches are tested under laboratory conditions at eight screed types including two samples thicknesses in each case. Moisture content and water release are measured by sample weighing, the corresponding relative humidity is measured by embedded sensors. All three approaches are compared and correlated. The evaluations show only a weak correlation and, in several cases, contradicting results. Samples are considered ready for layering and not ready for layering at the same time, depending on the chosen approach. Due to these contradicting results, a general threshold for a risk of damage cannot be derived based on these measurements. Furthermore, the experiment demonstrates that the measurement of corresponding relative humidity is independent of the screed type or screed composition considered. This makes humidity measurement a potentially very promising approach for the installation of material moisture monitoring systems.

scholarly journals Classification of brown earths based on field and laboratory properties: Problematic issues and proposition of their solution

2019 ◽  
Vol 52 (2) ◽  
pp. 225
Author(s):  
Karolina Woźnica ◽  
Agnieszka Józefowska ◽  
Justyna Sokołowska ◽  
Ryszard Mazurek ◽  
Tomasz Zaleski
Keyword(s):  
Calcium Carbonate ◽  
Main Parameter ◽  
Ph Value ◽  
Soil Classification ◽  
Base Saturation ◽  
Carbonate Content ◽  
Field Guide ◽  
Content Determination

<p class="Default">In this paper, the current problems associated with the classification of brown earths, are presented. According to the Polish Soil Classification (PSC) (1989, 2011), base saturation is the main parameter for identifying eutrophic and dystrophic brown soils. In practice, however, it is not possible to determine the base saturation value in the field. Therefore, the aim of this study was to estimate the base saturation using a regression equation and create a field guide for brown earths, based on the pH value, measured using a Hellige indicator, and the calcium carbonate content. Determination of the pH ranges enabled the classification of brown earth types in the field. These results suggest that pH can be used as a proxy for base saturation especially in the field. A change in the hierarchy of soil (sub)types is proposed for the new Polish Soil Classification.</p>

scholarly journals Spectrophotometric determination of Phenylephrine hydrochloride and Salbutamol sulphate drugs in pharmaceutical preparations using diazotized Metoclopramide hydrochloride

2015 ◽  
Vol 12 (1) ◽  
pp. 167-177 ◽  
Author(s):  
Baghdad Science Journal
Keyword(s):  
Limit Of Detection ◽  
Pharmaceutical Preparations ◽  
Correlation Coefficients ◽  
Limit Of Quantification ◽  
Pharmaceutical Dosage Forms ◽  
Salbutamol Sulphate ◽  
Phenylephrine Hydrochloride ◽  
Relative Standard ◽  
Metoclopramide Hydrochloride

A spectrophotometric method has been proposed for the determination of two drugs containing phenol group [phenylephrine hydrochloride (PHP) and salbutamol sulphate (SLB)] in pharmaceutical dosage forms. The method is based on the diazotization reaction of metoclopramide hydrochloride (MCP) and coupling of the diazotized reagent with drugs in alkaline medium to give intense orange colored product (?max at 470 nm for each of PHP and SLB). Variable parameters such as temperature, reaction time and concentration of the reactants have been analyzed and optimized. Under the proposed optimum condition, Beer’s law was obeyed in the concentration range of 1-32 and 1-14 ?g mL-1 for PHP and SLB, respectively. The limit of detection (LOD) and limit of quantification (LOQ) for each of PHP and SLB were 0.60, 0.52 ?g mL-1 and 2.02, 1.72 ?g mL-1, respectively. No interference was observed from common excipients present in pharmaceutical preparations. The good correlation coefficients and low relative standard deviation assert the applicability of this method. The suggested method was further applied for the determinations of drugs in commercial pharmaceutical preparations, which was compared statistically with reference methods by means of t- test and F- test and were found not to differ significantly at 95% confidence level. The procedure was characterized by its simplicity with accuracy and precision.

scholarly journals Spectrophotometric determination of metoclopramide hydrochloride in pharmaceutical tablets, by diazotization-coupling method with 1-naphthol as the coupling agent

2010 ◽  
Vol 7 (1) ◽  
pp. 704-712
Author(s):  
Baghdad Science Journal
Keyword(s):  
Detection Limit ◽  
Azo Dye ◽  
Diazonium Salt ◽  
Molar Absorptivity ◽  
British Pharmacopoeia ◽  
Pharmaceutical Tablets ◽  
Hydrochloric Acid Medium ◽  
Metoclopramide Hydrochloride ◽  
Sensitive Spectrophotometric Method

Simple, rapid and sensitive spectrophotometric method was proposed for the analysis of metoclopramide hydrochloride (MPH) in pure form as well as in pharmaceutical tablets. The method is based on the diazotization reaction of MPH with sodium nitrite in hydrochloric acid medium to form diazonium salt, which is coupled with 1-naphthol in sodium hydroxide medium to form azo dye, showing absorption maxima at 550 nm. Beer’s law is obeyed in the concentration range of 0.4 – 18 µg mL-1 of MPH with detection limit 0.5448 µg mL-1. The molar absorptivity and Sandell’s sensitivity are 3.4969 × 104 L mol-1 cm-1 and 0.0101 µg cm-2, respectively. The method was successfully applied to the determination of MPH in pharmaceutical tablets without any interference from common excipients used as additives in tablets. The results agree favorably with the official British Pharmacopoeia method.

scholarly journals Plant of Lamiaceae family for cultivation at the vertical hydroponic installation

2020 ◽  
pp. 72-75
Author(s):  
I. T. Balashova ◽  
L. V. Bespalko ◽  
A. V. Molchanova ◽  
E. V. Pinchuk ◽  
N. E. Maschenko
Keyword(s):  
Ascorbic Acid ◽  
Secondary Metabolites ◽  
Dry Matter ◽  
Matter Content ◽  
Leafy Vegetables ◽  
Dry Matter Content ◽  
Monarda Fistulosa ◽  
Vertical Farming ◽  
Content Determination

Relevance. Vertical farming – is a new and advanced direction in greenhouse vegetable cultivation. Expansion biodiversity of plants for vertical farming occur with help of green leafy vegetables. Plants of Lamiaceae family are well known as aromatic and medicinal plants with high content of substances with antioxidant activity. It allows use these plants as a base for the functional nutrition. Leafy parts the plants of Lamiaceae family may be used as aromatic and healthy additions to traditional foods, such as salads, soups and sauces.  Goal of the study: analysis the biochemical composition of leafy parts plants of Lamiaceaefamily, cultivated at the multi circle hydroponic construction. Materials and methods. 1) Plants: Monarda fistulosa L. (the breeding sample №5 U.P.), Monarda citriodora Cerv. ex Lag. (Simka variety), Melissa officinalisL. (Zhemchuzhina variety). 2) secondary metabolites: flavonoid glycoside linarozid and steroid glycoside moldstim. Methods. 1) cultivation of plants Lamiaceae family at the 5 circles hydroponic construction; 2) analytic methods: determination of dry matter content, determination of ascorbic acid content, determination sum of chlorophylls and carotenoids, determination sum of antioxidants; 3) statistical methods. Results. First experiment the cultivation of plants Lamiaceae family at the multi circle hydroponic construction was successful. Location of plants at different circles of hydroponic installation didn’t influence the content of dry matter, ascorbic acid and sum of chlorophylls in leafy parts of plants Monarda fistulosaL. The content of dry matter and sum of antioxidants in leafy parts of Monarda fistulosaL. plants of the first cutting is significantly higher than of other cuttings. So, we can recommend the leaves of Monarda fistulosa L. plants of the first cutting for the healthy additions in the scheme of the functional nutrition. Seed treatment with water solutions of secondary metabolites changed significantly the weight of leaves: it was increased in Monarda citriodoraCerv. ex Lag. and in Melissa officinalisL. 

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