Relation between different grades of pterygium and amount of induced corneal astigmatism

Background: Pterygium is more prevalent among people exposed to ultraviolet (UV) light. It occurs more often in people who live in warm climates and spend a lot of time outdoors in sunny or windy environments. Objective: The objective of this study was to determine and the relation of different grade of pterygium with amount of induced corneal astigmatism. Methodology: This was observational study done in LRBT hospital Multan road LHR. A self-designed Performa was filled after clinically examining the patients. Frequency distribution/percentages of data were described, simple frequency tables and cross tables were formed to calculate the statistical results. Results: A total patients 50 with grades of pterygium and induce amount of astigmatism. There 31(62.0%) were male and 19(38.0%) were female and the mean age of the patient is 2.5. 21(42.0%) patients were grade 1 pterygium and 21(42.0%) patients were grade 2 and 8(16.0%) patents have grade 3 pterygium. The amount of astigmatism in grade 1 from 0.00 to 1.00 DC is 17(34.0%) patients, from 1.00 to 2.00 DC are 2(4.0%) patients and from 2.00 to 4.00 DC are 2 (4.0%). In grade 2 from 1.00 to 2.00 DC are 10(20.0%) patients, from 2.00 to 4.00 DC are 10(20.0%) patients and from greater than 4.00 DC 1(2.0%). In grade 3 from 1.00 to 2.00 DC are 2(4.0%) patients, from 2.00 to 4.00 DC are 4(8.0%) patients and from greater than 4.00 DC are 2(4.0%) patients. Conclusion(s): Result show that the present study verifies that as the pterygium reaches more than 1.00mm in size from the limbus it induce with the rule astigmatism and pterygium size increases, the amount of induced astigmatism also increases with direct proportion.

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Prediction of surgically induced astigmatism in manual and femtosecond laser-assisted clear corneal incisions

European Journal of Ophthalmology ◽

10.1177/1120672117747017 ◽

2018 ◽

Vol 28 (4) ◽

pp. 398-405 ◽

Cited By ~ 2

Author(s):

Joaquín Fernández ◽

Manuel Rodríguez-Vallejo ◽

Javier Martínez ◽

Ana Tauste ◽

David P Piñero

Keyword(s):

Femtosecond Laser ◽

Corneal Astigmatism ◽

Toric Intraocular Lens ◽

Surgically Induced Astigmatism ◽

Orthogonal Components ◽

Induced Astigmatism ◽

The Mean ◽

Surgically Induced ◽

Corneal Incisions ◽

Intraocular Lens Calculation

Purpose: To assess the surgically induced astigmatism with femtosecond laser-assisted and manual temporal clear corneal incisions and to evaluate the performance of a model for prediction of the surgically induced astigmatism based on the preoperative corneal astigmatism. Methods: Clinical data of 104 right eyes and 104 left eyes undergoing cataract surgery, 52 with manual incisions and 52 with femtosecond laser-assisted incisions in each eye group, were extracted and revised retrospectively. In all cases, manual incisions were 2.2 mm width and femtosecond incisions were 2.5 mm width, both at temporal location. A predictive model of the surgically induced astigmatism was obtained by means of simple linear regression analyses. Results: Mean surgically induced astigmatisms for right eyes were 0.14D@65° (manual) and 0.24D@92° (femtosecond) (p > 0.05) and for left eyes, 0.15D@101° (manual) and 0.19D@104° (femtosecond) (p > 0.05). The orthogonal components of the surgically induced astigmatism (XSIA, YSIA) were significantly correlated (p < 0.05) with the preoperative orthogonal components of corneal astigmatism (Xpreop, Ypreop) (r = −0.29 for X and r = −0.1 for Y). The preoperative astigmatism explained 8% of the variability of the XSIA and 3% of the variability of YSIA. The postoperative corneal astigmatism prediction was not improved by the surgically induced astigmatism obtained from the model in comparison with the simple vector subtraction of the mean surgically induced astigmatism. Conclusion: Temporal incisions induce similar astigmatism either for manual or for femtosecond procedures. This can be clinically negligible for being considered for toric intraocular lens calculation due to the great standard deviation in comparison with the mean. The usefulness of the prediction model should be confirmed in patients with high preoperative corneal astigmatism.

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Counting Polar Symptoms: How to Represent Results?

Homeopathy ◽

10.1055/s-0040-1713363 ◽

2020 ◽

Author(s):

Lex Rutten ◽

José Eizayaga ◽

Harleen Kaur ◽

Chetna Deep Lamba ◽

Jyoti Sachdeva ◽

...

Keyword(s):

Observational Study ◽

Frequency Distribution ◽

Chronic Cough ◽

Prognostic Value ◽

Prospective Observational Study ◽

Mean Value ◽

Centre Of Mass ◽

Central Council ◽

The Mean

Abstract Background Polar symptoms (PS)—symptoms with opposite values—are frequently used in homeopathy, but have many misleading entries in the repertory. This is caused by using absolute occurrence of symptoms, causing the same medicine to appear in both (opposite) symptom rubrics, and by lack of comparison with other medicines. Some PS, like ‘aversion/desire for sweets’ have a frequency distribution that is not evenly distributed around the neutral value: a desire for sweets is much more common than aversion. A desire for sweets is an indication for a specific medicine only if this desire occurs more frequently in this specific medicine population than in the remainder of the population. We need to find the best way to represent this difference. Methods A multi-centre, explorative, prospective, observational study was conducted by nine centres of the Central Council for Research in Homoeopathy. Two-hundred and sixteen patients were enrolled with chronic cough lasting more than 8 weeks, and received usual homeopathic care. During intake, 30 general PS, 27 polar cough symptoms and 3 non-polar cough symptoms were checked. Different ways of representing results were explored, including two quantities borrowed from mechanics: Centre of Mass (CoM) and Leverage. Results At the fourth follow-up, three medicines with more than 10 cases with good results were identified: 20 Phosphorus, 19 Pulsatilla and 13 Sulphur. The mean value of the frequency distribution of some symptoms in the whole sample was considerably different from the neutral value. Comparing a medicine population with the remainder of the respective population can give results that differ from polarity analysis. For some symptoms, the ‘distance’ (Leverage) between the CoMs of the medicine population and the remainder of the population was clearer than the likelihood ratio (LR). Conclusion If the LR value is not clear about the prognostic value in PS, notions from mechanics such as CoM and Leverage can clarify how to interpret a polar symptom.

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Pre-existing Corneal Astigmatism in patients undergoing Cataract Surgery in Western Nepal; A hospital-based Unicentered, Comprehensive, Prospective Observational Study

Nepal Journal of Medical Sciences ◽

10.3126/njms.v5i2.36707 ◽

2020 ◽

Vol 5 (2) ◽

pp. 21-25

Author(s):

Shristi Shrestha ◽

Khemraj Kaini

Keyword(s):

Visual Acuity ◽

Cataract Surgery ◽

Corneal Astigmatism ◽

Cross Sectional ◽

Postoperative Visual Acuity ◽

Department Of Ophthalmology ◽

Induced Astigmatism ◽

Different Populations ◽

The Mean ◽

Surgically Induced

Introduction: Cataract surgery is one of the most commonly performed surgical procedures worldwide. The final postoperative visual acuity is dependent on the pre-existing corneal astigmatism, accurate biometry and surgically induced astigmatism. Because of the increase in the patient’s demand for better postoperative visual acuity, it becomes important to evaluate the distribution of pre-existing corneal astigmatism in different populations. The objective of the study was to analyze the magnitude and pattern of pre-existing corneal astigmatism in cataract surgery patients in Western Nepal.Methods: A hospital-based cross-sectional descriptive study was carried out in the Department of Ophthalmology, Manipal Teaching Hospital, Pokhara. Three hundred and two patients undergoing routine cataract surgery between February 2016 and January 2018 were recruited in the study. Keratometric data from these patients were collected and were analyzed using the statistical software SPSS version 21.Results: The mean age of the subjects was 70.25 ± 10.97 years (range 35 to 94 years). There was a preponderance of females (62%) over males (38%). The mean corneal astigmatism was 0.78 ± 0.59 D (range 0.00 to 5.00 D). The pre-existing corneal cylinder ≥ 1.00 D was seen in 40.06% of patients. The corneal astigmatism was mainly against the rule (65.56%). The amount of corneal astigmatism and corneal steepness increased with age.Conclusion: Corneal astigmatism of 1.00 D or more was seen in 40.06% of the patients undergoing cataract surgery which should be corrected to meet the patient’s expectation for good, unaided visual acuity after cataract surgery.

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Profil Penyakit Malaria Di Rumah Sakit Islam Siti Rahmah Padang Tahun 2018

Health & Medical Journal ◽

10.33854/heme.v2i2.546 ◽

2020 ◽

Vol 2 (2) ◽

pp. 08-15

Author(s):

Rahma Triyana ◽

Salmi Salmi

Keyword(s):

Observational Study ◽

Frequency Distribution ◽

Cross Section ◽

Laboratory Tests ◽

Age Group ◽

Normal Range ◽

Cross Sectional ◽

West Sumatra ◽

Severity Of The Disease

Malaria is one of the health problems in Indonesia, especially West Sumatra. Determination of the description of Malaria disease in an area is needed to determine the spread and severity of the disease. This study aims to determine the frequency distribution according to age, sex and place of residence, description of the types of Plasmodium causes of Malaria and hematological features in Malaria patients at Siti Rahmah Padang Hospital in 2018. This type of research is a descriptive observational study with an approach or design cross section (cross sectional). The frequency distribution of Malaria sufferers in Siti Rahmah Padang Hospital in 2018 according to the highest age was in the age group 21-30 years as many as 28 cases (36.8%), the highest sex among men was 46 (60.5%) and the highest number of residences was found in Koto Tangah sub-district there were 31 cases (40.8%). The type of Plasmodium found in Malaria cases in Siti Rahmah Padang Hospital in 2018 was P. vivax (73 cases (96.05%)) and P. falciparum (3 cases (3.95%)). The results of laboratory tests on Hb, hematocrit, platelet and leukocyte levels in Malaria positive patients in Siti Rahmah Padang Hospital in 2018 were in the normal range.

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Profil Penyakit Malaria di Rumah Sakit Islam Siti Rahmah Padang Tahun 2018

Health & Medical Journal ◽

10.33854/heme.v2i2.452 ◽

2020 ◽

Vol 2 (2) ◽

pp. 08-15

Author(s):

Rahma Triyana Y ◽

Salmi Salmi

Keyword(s):

Observational Study ◽

Frequency Distribution ◽

Cross Section ◽

Laboratory Tests ◽

Age Group ◽

Normal Range ◽

Cross Sectional ◽

West Sumatra ◽

Severity Of The Disease

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The Structure and Photochromism of 2,4,4,6-Tetraphenyl-4H-thiopyran

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc19921326 ◽

1992 ◽

Vol 57 (6) ◽

pp. 1326-1334 ◽

Cited By ~ 11

Author(s):

Jaroslav Vojtěchovský ◽

Jindřich Hašek ◽

Stanislav Nešpůrek ◽

Mojmír Adamec

Keyword(s):

Solid State ◽

Uv Light ◽

Order Reaction ◽

Boat Conformation ◽

X Rays ◽

Exponential Time ◽

First Order ◽

Double Plane ◽

The Mean ◽

Independent Molecules

2,4,4,6-Tetraphenyl-4H-thiopyran, C29H22S, orthorhombic, Pna21, a = 17.980(4), b = 6.956(2), c = 34.562(11) Å, V = 4323(2) Å3, Z = 8, Dx = 1.237 g cm-3, F(000) = 1696, λ(CuKα) = 1.54184 A, μ = 1.372 mm-2, T = 294 K. The final R was 0.050 for the unique set of 3103 observed reflections. The central 4H-thiopyran ring forms a boat conformation for both symmetrically independent molecules with average boat angles 4.4(3) and 6.8(3)° at S and C(sp3), respectively. The mean planes of phenyls at the position 2 and 6 are turned from the double plane of 4H-thiopyran by 42.5(5) and 35.8(3)°, respectively. The investigated material undergoes a photochromic change in the solid state after irradiation with UV light or X-rays. The maximum of the new absorption band is situated at 564 nm. The non-exponential time dependence of photochromic bleaching is analysed in terms of a dispersive first-order reaction.

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Exercise Intensity during Olympic-Distance Triathlon in Well-Trained Age-Group Athletes: An Observational Study

Sports ◽

10.3390/sports9020018 ◽

2021 ◽

Vol 9 (2) ◽

pp. 18

Author(s):

Atsushi Aoyagi ◽

Keisuke Ishikura ◽

Yoshiharu Nabekura

Keyword(s):

Heart Rate ◽

Observational Study ◽

Exercise Intensity ◽

Time Range ◽

Age Group ◽

Slow Group ◽

H 41 ◽

The Mean ◽

Aerobic And Anaerobic ◽

Very High

The aim of this study was to examine the exercise intensity during the swimming, cycling, and running legs of nondraft legal, Olympic-distance triathlons in well-trained, age-group triathletes. Seventeen male triathletes completed incremental swimming, cycling, and running tests to exhaustion. Heart rate (HR) and workload corresponding to aerobic and anaerobic thresholds, maximal workloads, and maximal HR (HRmax) in each exercise mode were analyzed. HR and workload were monitored throughout the race. The intensity distributions in three HR zones for each discipline and five workload zones in cycling and running were quantified. The subjects were then assigned to a fast or slow group based on the total race time (range, 2 h 07 min–2 h 41 min). The mean percentages of HRmax in the swimming, cycling, and running legs were 89.8% ± 3.7%, 91.1% ± 4.4%, and 90.7% ± 5.1%, respectively, for all participants. The mean percentage of HRmax and intensity distributions during the swimming and cycling legs were similar between groups. In the running leg, the faster group spent relatively more time above HR at anaerobic threshold (AnT) and between workload at AnT and maximal workload. In conclusion, well-trained male triathletes performed at very high intensity throughout a nondraft legal, Olympic-distance triathlon race, and sustaining higher intensity during running might play a role in the success of these athletes.

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Comparison of corneal astigmatism characteristics and prevalence of corneal astigmatism between Turkish individuals and Syrian refugees

European Journal of Ophthalmology ◽

10.1177/11206721211030779 ◽

2021 ◽

pp. 112067212110307

Author(s):

Soner Guven

Keyword(s):

Quantitative Analysis ◽

Cataract Surgery ◽

Corneal Astigmatism ◽

Syrian Refugees ◽

Vector Method ◽

Adjusted Analysis ◽

Younger Age ◽

The Mean ◽

Age And Sex

Purpose: To compare the prevalence, magnitude and type of corneal astigmatism between Turkish individuals and Syrian refugees. Material and methods: Data of patients scheduled for cataract surgery between January 2019 and 2020 were reviewed. The patients were randomly stratified according to their ethnicity (Turkish individuals or Syrian refugees). Keratometry was performed with the keratometer of IOLMaster 500. Quantitative analysis was performed using the power vector method (J0 and J45). The association between age and astigmatism in the two groups was explored. Results: The study included 4085 eyes of 2049 patients (3962 eyes of Turkish individuals and 123 eyes of Syrian refugees). The mean magnitude of corneal astigmatism, J0, J45 and prevalence of against the rule (ATR) astigmatism and with the rule (WTR) astigmatism were 1.01 D, 0.06, 0.01 D, 37.6% and 43.7% in Turkish individuals and 1.13 D, −0.02, 0.07 D, 46.3% and 37.4% in Syrian refugees, respectively. There were no significant differences according to age, sex, right/left eyes, corneal astigmatism magnitude, keratometric values, J0 and J45 ( p > 0.05) between the two groups. Below 40 years of age, the mean corneal astigmatism magnitude in Syrian refugees was significantly higher than that in Turkish individuals ( p = 0.037). At all ages, ATR astigmatism prevalence was higher in Syrian refugees than in Turkish individuals. ATR astigmatic shift began at a younger age in Syrian refugees ( p = 0.037). Age- and sex-adjusted analysis showed that J0 was significantly lower in Syrian refugees than in Turkish individuals ( p = 0.013). Conclusion: The prevalence and magnitude of ATR astigmatism were higher and onset earlier in Syrian refugees than in Turkish individuals.

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AB0189 ASSESSMENT OF POWER DOPPLER SYNOVITIS IN RHEUMATOID ARTHRITIS PATIENTS WITH CLINICAL REMISSION

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2020-eular.6064 ◽

2020 ◽

Vol 79 (Suppl 1) ◽

pp. 1394.2-1394

Author(s):

R. Fakhfakh ◽

N. El Amri ◽

K. Baccouche ◽

H. Zeglaoui ◽

E. Bouajina

Keyword(s):

Rheumatoid Arthritis ◽

Functional Capacity ◽

Clinical Remission ◽

Power Doppler ◽

Health Assessment ◽

Disease Flare ◽

Synovial Hypertrophy ◽

The Mean ◽

Grade 3 ◽

Subclinical Synovitis

Background:Ultrasound-detected synovitis, mainly synovial Doppler signal, has shown predictive value in relation to radiographic damage progression and disease flare or relapse in rheumatoid arthritis (RA) patients with clinical remission.Objectives:The aim of the study was to analyze the correlation between power Doppler scores and clinical/laboratory and radiographic data in clinical remission RA patients.Methods:Cross-sectional study including patients with RA in clinical remission defined by: DAS28ESR ≤ 2.6, without disease flare or changes in therapy in the previous 6 months. Each patient underwent ultrasound: B-mode and PD assessments of 36 joints and 20 tendons in the Rheumatology Department over a period of 6 month. Synovitis and tenosynovitis were defined and scored according to the Outcome Measures in Rheumatology Clinical Trials (OMERACT). Radiological measurements included the modified Sharp/van der Heijde method (SHS). Functional capacity was assessed by the Health Assessment Questionnaire (HAQ).Results:Thirty two patients were enrolled, the mean age was 53.7±13.4 and 75% were female. The mean disease duration was 15 years ± 8.8. Subclinical synovitis were the most frequent in wrist (56.3%), 2ndmetacarpophalangeal joints (28.1%) and 2ndmetatarsophalangeal joints (29%). The mean subclinical synovitis/ tenosynovitis numbers was 4±3.1 per patient. Synovial hypertrophy and B mode tenosynovitis were detected in 93.8%: 71.3% had a grade = 2 and 9.8% had a grade= 3. Total B mode score was correlated only with the SHS score in the feet (r: 0.4, p: 0.03). PD signal was detected in 62.5% of patients: 37.5% had a grade =2 and 9.4% had a grade= 3. Total PD score was correlated with DAS28 (r:0.42, p:0.02), the SHS score in the hands (r:0.39, p:0.03) and in the feet (r:0.5, p:0.007), synovial hypertrophy (r:0.6, p:0.0001) and HAQ (r:0.32, p:0.06). No correlation was found with CDAI, SDAI, swollen joint counts, tender joint counts, patient global health assessment, erythrocyte sedimentation rate, C-reactive protein, rheumatoid factor and anti-cyclic citrullinated peptide, biologic treatment.Conclusion:Synovial hypertrophy and PD signal were frequent in RA remission. PD signal was associated with RA activity, radiologic damage and functional capacity.References:[1]Yan Geng & Jingjing Han & Xuerong Deng and al. Presence of power Doppler synovitis in rheumatoid arthritis patients with synthetic and/or biological disease-modifying anti-rheumatic drug-induced clinical remission: experience from a Chinese cohort. Clinical Rheumatology 2014. DOI 10.1007/s10067-014-2634-yDisclosure of Interests:None declared

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Does pterygium morphology affect corneal astigmatism?

Therapeutic Advances in Ophthalmology ◽

10.1177/25158414211030423 ◽

2021 ◽

Vol 13 ◽

pp. 251584142110304

Author(s):

Emine Doğan ◽

Burçin Çakır ◽

Nilgün Aksoy ◽

Elif Köse ◽

Gürsoy Alagöz

Keyword(s):

Anterior Segment ◽

Clinical Information ◽

Corneal Astigmatism ◽

Continuous Group ◽

Optic Coherence Tomography ◽

Morphological Pattern ◽

Horizontal Length ◽

The Mean ◽

Anterior Corneal Astigmatism ◽

Posterior Corneal Astigmatism

Purpose: The purpose of this study was to evaluate the correlation between corneal astigmatism and the morphology of pterygium with anterior segment optic coherence tomography (AS-OCT). Material and Methods: The size of pterygium (horizontal length, vertical width) was measured manually; pterygium area and percentage extension of the pterygium onto the cornea were calculated. Anterior and posterior corneal astigmatism, Sim K, K1, K2 were measured using a dual Scheimpflug analyzer. Morphological patterns of the pterygium analyzed with AS-OCT were determined according to the extension of the pterygium apex below the corneal epithelium. Two tomographic patterns were identified: continuous and nodular. Correlation between anterior corneal astigmatism and pterygium size, percentage extension of the pterygium, and morphological pattern of the pterygium was analyzed. Results: The mean ages of the 47 patients were 49.4 ± 16.6 (22–80) years. Mean horizontal pterygium length, vertical width, pterygium area, and percentage extension of the pterygium were 2.8 ± 1.2 mm, 4.8 ± 1.6 mm, 7.42 ± 5.6 mm2 and 24.5 ± 10.4%, respectively. Mean anterior corneal astigmatism was 2.3 ± 2.3 D and simulated keratometry was 43.4 ± 2.02 D. In terms of the morphological pattern of the pterygium, 24 eyes had continuous, 23 eyes had a nodular pattern and the median (interquartile range) anterior corneal astigmatism was 1.87 (1.01–3.80) and 1.22 D (0.58–2.35), respectively ( p = 0.102). Other topographic and pterygium size parameters were similar between groups. Analyzing the correlations in groups separately, a positive moderate statistically significant correlation was present between vertical width, percentage extension, pterygium area, and anterior corneal astigmatism in both continuous and nodular groups. Conclusions: Although not statistically significant, anterior corneal astigmatism was higher in continuous group. Using AS-OCT to standardize the morphology of pterygium could provide additional clinical information.

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