scholarly journals Effect of glimepiride compared with glibenclamide on post prandial blood sugar in type II diabetes mellitus patients

Author(s):  
Meenu Rani ◽  
Shailesh Yadav ◽  
Seema Choudhary ◽  
Seema Sharma ◽  
Surya Pandey
2019 ◽  
Vol 1 ◽  
pp. 50-64
Author(s):  
DEVASHISH BHARDWAJ ◽  
VEENIT K. AGNIHOTRI ◽  
PRANAV PANDYA

A research plan has been developed in the present study to address the problems associated with Avaranajanya Madhumeha (type 2 diabetes). This research plan is based on the treatment methods of Ayurveda (ancient Indian medicine) and utilization of modern scientific methods as research tools. A specific ayurvedic herbo-mineral formulation has been prepared in Ghansatt (solid extract) form; the selected eight herbs and one herbo-mineral have anti-hyperglycemic (PRAMEHA HARA) and antihypercholestermic (MEDOHARA) properties with rejuvenative (RASAYANA) effects as described in classical ayurvedic methods. 15 diagnosed type II diabetes mellitus patients were selected through accidental sampling. Ayurvedic formulation was prescribed to type II diabetes patients for one year along with dietary restrictions. Diabetic diagnostic parameters of these patients like Fasting Blood Sugar (FBS), Post Patrum Blood Sugar (PPBS), Glycocylated Hemoglobin (HbA1C) and Urine Sugar Fasting were monitored every three months; these were measured before and after intervention. The obtained data were statistically analyzed through paired t-test. There was significant reduction in FBS level, PPBS level, HbA1C level and urine fasting sugar level in type 2 diabetes patients who completed the clinical trial successfully. Thus, ayurvedic formulation treatment lead to an overall significant reduction in blood sugar and urine sugar levels in type II diabetes patients. No side effects were noted during the study period. This study suggests that the ayurvedic formulation had very good hypoglycemic effects proved by clinical improvement and bio-chemical analysis of diabetes parameters in the treatment of type II diabetes mellitus.


Author(s):  
Talib Mearza ◽  
Wesam Abou Amer ◽  
Maryam Al Jaber

Type II diabetes is caused by insulin resistance resulting in high blood sugar levels. Although the typical symptoms of diabetes are described as polyuria, polydipsia and fatigue as many as 60% of newly diagnosed patients with type II diabetes are asymptomatic. Here authors present a case of a 39-year-old male patient who presented with localized pruritus affecting the medial aspects of his forearms and upper legs as the sole symptom of newly diagnosed type II diabetes mellitus. The itch symptom markedly improved on significantly reducing his dietary intake of sugars and with the use of metformin. Authors hope to alert clinicians to consider the possibility of underlying diabetes in such presentations to enable swift diagnosis and consequent treatment. It is unusual to find patients presenting with localized itch without any corresponding cutaneous manifestations as a presentation of type II diabetes.


2019 ◽  
Vol 4 (1) ◽  

A study was carried out, in order to assess the risk factors associated with type-II diabetes mellitus in males (Age≥40 years) in district Mardan. Four hundred cases and controls (Each 200) were selected from 10 union councils (7 rural and 3 urban) by a systematic sampling method. In order to select cases and controls, all were interviewed for medical history, on fulfillment of which, cases and controls were separately included for study. In anthropometry, weight, and height were taken for Body Mass Index while waist and hip circumference were taken for waist-to-hip ratio. Fasting blood sugar of cases and controls was determined with the glucometer. Cases and controls were interviewed with Food frequency questionnaire and other questionnaires in order to assess the demographic and socioeconomic characters of the families. The results disclosed that most of the cases had family history of diabetes. In addition to that, cases were also found to have higher (p<0.05) average weight, height and body mass index, and fasting blood sugar level to those of controls. These results also revealed that there was a distinguished (p<0.05) association between dairy and fruit with the health status and about 1/3rd of both cases and controls had satisfactory consumption of dairy and fruit only. A significant link was found among family size, exercise, type of exercise, duration of exercise, watching television, duration of watching television and the status of disease. The study revealed that a combination of anthropometric, dietary and demographic variables were associated with type-II diabetes mellitus in male adult population of district Mardan.


2021 ◽  
pp. 42-43
Author(s):  
Neena Damle

During the last few years India have maximum increase of Type II diabetes mellitus . The prevalence of type 2 diabetes mellitus is 2.4% in rural population and 11.6% in urban population[1] . In this study total 10 Subjects of newly diagnosed type II Diabetes Mellitus, who fullled below criteria were selected from D.Y. Patil Ayurvedic Hospital Nerul Navi Mumbai OPD No.1. a) HbA1c level more than 6.5% b) Fasting blood Sugar level (FBS) more than 126 mg/dL (7 mmol/L) c) 2-hour Post Prandial Blood Sugar level (PPBS) more than 200 mg/dL (11.1 mmol/L). All 10 subjects treated with Nisha Amalaki Churna 3gms BD one hour before breakfast and before dinner with warm water for three months. Data of subjective parameters and physical examination of subjects was recorded in CRF during three visits 30 days apart. For Statistical Analysis Wilcoxon matched-pairs signed-ranks test was used to assess Subjective parameters and Paired t-Test was used to compare Fasting Blood Sugar level, two hour post prandial blood sugar levels and HbA1C levels BT and AT. The study showed signicant results in most of the subjective parameters at the level of signicance (P<0.05). Nisha Amalaki Churna reduced Fasting blood sugar levels and post Prandial blood sugar levels signicantly at level of signicance p<0.01. Nisha Amalaki Churna also reduced HbA1C levels signicantly at level of signicance p<0.01.The Ayurvedic mixture Nisha Amalaki Churna was signicantly effective in newly diagnosed Type II Diabetes Mellitus subjects.


2021 ◽  
Vol 1 (2) ◽  
pp. 112-117
Author(s):  
Fahruddin Kurdi ◽  
Zainal Abidin ◽  
Ratna Puji Priyanti ◽  
Anja Hesnia Kholis

Elderly are high risk for the development of type 2 diabetes due to the combined effects of increasing insulin resistance and impaired pancreatic function with aging. Diabetes mellitus is a chronic disease that causes insulin in the pancreas is not effective one of the treatments that can be done by diabetics to reduce blood sugar levels One of them with physical activity, the activity is taichi exercises.The purpose of this study was to investigate the effect of taichi exercises on reducing blood sugar levels in patients with type II diabetes mellitus.The design of this study was pre-experiment one group pre-test and post-test design with a population of 88 patients and a sample of 44 respondents. Research sampling technique used purposive sampling. Data collection with observation sheets. The intervention was carried out four times during 4 weeks. Before the intervention, sugar levels of type II diabetics were classified as moderate as 24 people (54.5%) and high as many as 20 people (45.5%). After the management of taichi exercises sugar levels experienced changes in the categories of good as many as 16 people (36.4%), moderate as many as 20 people (45.5%) and high as many as 8 people (18.2%). Data analized with Wilcoxon Signed Rank test with a significant level α = 0.05, the result ρ-value = 0.001 means ρ-value <α so that there is a significant effect of taichi exercises on decreasing blood sugar levels in patients with type II diabetes mellitus. Blood sugar levels in patients with diabetes mellitus before doing taichi exercises with the number of respondents 44 people mostly experienced changes, evidenced by the level of blood sugar levels from moderate levels to good. Keywords: Elderly, Taichi, Diabetes Mellitus, Blood sugar level


2019 ◽  
Vol 1 (1) ◽  
pp. 157-167
Author(s):  
Ariska Ariska

The purpose of this study was to identify the effectiveness of giving aloe vera boiled water to decrease blood sugar levels in type II Diabetes Mellitus patients at Batunyala Community Health Center, Central Praya District, Central Lombok Regency, NTB. The research design used in this study is a quasi-experimental design pre and post with control group. Respondents were patients who had been treated at Batunyala Health Center, Praya Tengah District, Central Lombok Regency, NTB and diagnosed with type II diabetes mellitus. The total sample in this study was 22 samples with 11 respondents in the intervention group and 11 respondents in the control group using porposivesampling technique. The results of the Dependent t test in getting the results of the average blood sugar level before intervention was 178.73 and after the intervention was 172.18 with an average decrease of 2.258. The results of the Dependent T test obtained P value (0.016) <(0.05) and t count (2.899)> t table (1,812) then Ho was rejected meaning that there were differences in blood sugar levels before and after the intervention giving aloe vera water.   Key words : Aloe Vera, Blood Sugar Levels, Type II Diabetes Mellitus 


2019 ◽  
Vol 1 (1) ◽  
pp. 191-204
Author(s):  
Riandi Alfin ◽  
Busjra Busjra ◽  
Rohman Azzam

The purpose of this research is to know the influence of Ramadan Fasting towards blood sugar levels in diabetics in the health center in West Java of Purwakarta. The design of this research uses quasi experiment of pre and post test with the control group, the method uses Purposive sampling done by the sum of 36 samples of respondents. The results of this research are using Independent T-test fast differences in blood sugar levels after fasting Ramadaan in the control group and the intervention group obtained the value of p = 0.039 < α = 0.05. Conclusion the results of this study showed the presence of the influence of fasting of Ramadan towards blood sugar levels in type II diabetes mellitus patients in Healty Center of Purwakarta. It can be concluded that fasting during Ramadan can be used as an alternative diet method that has positive benefits if it is run by type II diabetes mellitus patients which can reduce blood sugar to be more stable.  Keywords: Ramadhan Fasting, Blood Glukose Level, Diabetic Mellitus Type II


QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
A H A Youssef ◽  
H M Elmaleh ◽  
M M H Khalil ◽  
E A A Qamry

Abstract Background obesity and its associated type II diabetes mellitus (Type II DM) are an ongoing health-care problem worldwide. Both diseases are closely related and difficult to control by current medical treatment, including diet, drug therapy and behavioral modification. There is strong evidence that bariatric surgery can cure type II diabetes mellitus in patients with obesity. Aim of the Work to determine different predictive factors affecting the outcome of type II diabetes mellitus after laparoscopic sleeve gastrectomy. Patients and Methods this prospective study included 40 obese diabetic patients with type II DM who underwent laparoscopic sleeve gastrectomy. DM type II was diagnosed according to ADA criteria: FPG &gt; 126 mg/dl, HbA1c ≥ 6.5%, random blood glucose ≥200 mg/dl, or use of insulin or oral diabetes medication. Glycemic marker in the form of HbA1c and fasting blood sugar were measured just prior to surgery and at 3 months and 6 months postoperatively. Results a total of 40 patients (70% women) with T2DM were included in the study. Mean age at the time of surgery was 42.48 ± 10.95 years. Median Inter Quartile Ratio (IQR) of diabetes age (diabetes age was calculated from the diagnose date to the operation date) was 4 years (from 3 years to 6 years) with range of 1-20 years. Remission of T2DM was achieved in 42.5% of patients underwent SG. Conclusion This study showed that younger patients, with shorter diabetic age, not using insulin and optimum pre-operative glycemic control(normal fasting blood sugar and HbA1c) were the best candidates to achieve remission (HbA1c &lt;6.5% and no need for antidiabetics) after SG.


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