scholarly journals Application of dendrimers and quantum dots in cancer diagnosis and therapy

2018 ◽  
Vol 48 (1-2) ◽  
Author(s):  
Emir Horozić
Keyword(s):  
Quantum Dots ◽  
Magnetic Resonance ◽  
Cancer Therapy ◽  
Cancer Patients ◽  
Tumor Cells ◽  
Cancer Diagnosis ◽  
Safe Delivery ◽  
Pass Through ◽  
Cancer Diagnosis And Therapy ◽  
Diagnosis Of Diseases

The use of nanotechnology in the diagnosis of diseases, treatment and monitoring of cancer patients has become a subject of study for the last 20 years. This paper presents brief overview of general characteristics, synthesis and application of dendrimers and quantum points in oncology. Dendrimers and quantum dots are nanostructures whose application in oncology is still being examined. QDs are used in magnetic resonance, wherein very well detect the location of tumor. Dendrimers are intensively tested, especially in cancer therapy. Dendrimers are intensively tested, especially in cancer therapy, because, due to their extremely small dimensions, they have the ability to pass through the mucous barriers and vascular pores, enabling safe delivery of the drug to the tumor cells.

Trends in Nanotechnology for in vivo Cancer Diagnosis: Products and Patents

2020 ◽  
Vol 26 (18) ◽  
pp. 2167-2181
Author(s):  
Tatielle do Nascimento ◽  
Melanie Tavares ◽  
Mariana S.S.B. Monteiro ◽  
Ralph Santos-Oliveira ◽  
Adriane R. Todeschini ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Quantum Dots ◽  
Magnetic Resonance ◽  
Metal Nanoparticles ◽  
Cancer Diagnosis ◽  
Imaging Techniques ◽  
Tumor Detection ◽  
Abnormal Growth ◽  
Pharmaceutical Nanotechnology

Background: Cancer is a set of diseases formed by abnormal growth of cells leading to the formation of the tumor. The diagnosis can be made through symptoms’ evaluation or imaging tests, however, the techniques are limited and the tumor detection may be late. Thus, pharmaceutical nanotechnology has emerged to optimize the cancer diagnosis through nanostructured contrast agent’s development. Objective: This review aims to identify commercialized nanomedicines and patents for cancer diagnosis. Methods: The databases used for scientific articles research were Pubmed, Science Direct, Scielo and Lilacs. Research on companies’ websites and articles for the recognition of commercial nanomedicines was performed. The Derwent tool was applied for patent research. Results: This article aimed to research on nanosystems based on nanoparticles, dendrimers, liposomes, composites and quantum dots, associated to imaging techniques. Commercialized products based on metal and composite nanoparticles, associated with magnetic resonance and computed tomography, have been observed. The research conducted through Derwent tool displayed a small number of patents using nanotechnology for cancer diagnosis. Among these patents, the most significant number was related to the use of systems based on metal nanoparticles, composites and quantum dots. Conclusion: Although few systems are found in the market and patented, nanotechnology appears as a promising field for the development of new nanosystems in order to optimize and accelerate the cancer diagnosis.

scholarly journals Modeling the Treatment of Glioblastoma Multiforme and Cancer Stem Cells with Ordinary Differential Equations

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Kristen Abernathy ◽  
Jeremy Burke
Keyword(s):  
Stem Cells ◽  
Glioblastoma Multiforme ◽  
Cancer Therapy ◽  
Cancer Stem Cells ◽  
Differential Equations ◽  
Ordinary Differential Equations ◽  
Cancer Patients ◽  
Tumor Cells ◽  
Tumor Recurrence ◽  
Common Event

Despite improvements in cancer therapy and treatments, tumor recurrence is a common event in cancer patients. One explanation of recurrence is that cancer therapy focuses on treatment of tumor cells and does not eradicate cancer stem cells (CSCs). CSCs are postulated to behave similar to normal stem cells in that their role is to maintain homeostasis. That is, when the population of tumor cells is reduced or depleted by treatment, CSCs will repopulate the tumor, causing recurrence. In this paper, we study the application of the CSC Hypothesis to the treatment of glioblastoma multiforme by immunotherapy. We extend the work of Kogan et al. (2008) to incorporate the dynamics of CSCs, prove the existence of a recurrence state, and provide an analysis of possible cancerous states and their dependence on treatment levels.

Application of Nanocomposites in Cancer Immunotherapy

Nano LIFE ◽  
2017 ◽  
Vol 07 (03n04) ◽  
pp. 1750008
Author(s):  
Wenhan Liu ◽  
Zejun Wang ◽  
Yao Luo ◽  
Nan Chen
Keyword(s):  
Immune System ◽  
Cancer Therapy ◽  
Cancer Treatment ◽  
Cancer Immunotherapy ◽  
Cancer Patients ◽  
Tumor Cells ◽  
Tumor Immunity ◽  
Critical Role ◽  
Clinical Advances ◽  
Review Current

Despite the clinical advances in oncology, cancer is still the major cause of death worldwide. Recent research demonstrates that the immune system plays a critical role in preventing tumor occurrence and development. The focus on cancer treatment has been shifted from directly targeting the tumor cells to motivating the immune system to achieve this goal. However, the activity of immune system is often suppressed in cancer patients. To boost the anti-tumor immunity against cancers, various nanocomposites have been developed to enhance the efficacy of immunostimulatory agents. Here, we review current advances in nanomaterial-mediated immunotherapy for the treatment of cancer, with an emphasis on applications of nanocomposites as immunoadjuvants in cancer therapy.

Psychological Ladder in Oral Cancer Patients

2021 ◽  
Author(s):  
Jeyaraman Swathiraman
Keyword(s):  
Oral Cancer ◽  
Cancer Patients ◽  
Family Caregivers ◽  
Cancer Diagnosis ◽  
Family Role ◽  
Common Cancer ◽  
The World ◽  
Oral Cancer Patients ◽  
Cancer Diagnosis And Therapy

Oral cancer ranks sixth most common cancer in the world. Smoking and alcohol consumption consider to the major risk factor. Despite recent advances in cancer diagnosis and therapy the 5 years survival rate of oral cancer patient has remains low. During the advance stage of changes in family role and the burden placed on family caregivers negatively affect quality of life for cancer patients as well the caregivers. Treatment of oral cancer usually requires surgery which results in transformed facial appearance, which may be the cause of separation of the patient from the society and leads to psychological distress.

scholarly journals Semiconductorversusgraphene quantum dots as fluorescent probes for cancer diagnosis and therapy applications

2018 ◽  
Vol 6 (18) ◽  
pp. 2690-2712 ◽  
Author(s):  
Aliaksandra Rakovich ◽  
Tatsiana Rakovich
Keyword(s):  
Quantum Dots ◽  
Cancer Diagnosis ◽  
Fluorescent Probes ◽  
Semiconductor Quantum Dots ◽  
Diagnosis And Therapy ◽  
Cancer Diagnosis And Therapy

This review provides a comparison of optical, chemical and biocompatibility properties of graphene and semiconductor quantum dots as fluorescent probes.

HYBRID NANOMATERIALS CONTAINING PAMAM, POLYROTAXANE AND QUANTUM DOT BLOCKS

NANO ◽  
2011 ◽  
Vol 06 (03) ◽  
pp. 239-249 ◽  
Author(s):  
MOHSEN ADELI ◽  
REZA SADEGHI SARABI ◽  
ELHAM SADEGHI
Keyword(s):  
Thermal Analysis ◽  
Quantum Dots ◽  
Polyethylene Glycol ◽  
Quantum Dot ◽  
Aqueous Solutions ◽  
Cancer Diagnosis ◽  
Room Temperature ◽  
Water Solubility ◽  
Hybrid Nanomaterials ◽  
Cancer Diagnosis And Therapy

Pseudopolyrotaxanes, Ps-PR, consisting of α-cyclodextrin rings, polyethylene glycol axes and end triazine groups were prepared and then were capped by amino-functionalized quantum dots, NH2 -QDs, to achieve polyrotaxanes. The amino-functionalized QDs stoppers of polyrotaxanes were used as core to synthesize polyamidoamine, PAMAM, dendrons divergently and hybrid nanomaterials were obtained. Synthesized hybrid nanomaterials were characterized by different spectroscopy, microscopy and thermal analysis methods. They were freely soluble in water and their aqueous solutions were stable at room temperature over several months. Due to their biocompatible backbone, high functionality and water solubility synthesized hybrid nanomaterials are promising carriers and probes in cancer diagnosis and therapy.

Highly efficient photothermal heating via distorted edge-defects in boron quantum dots

2020 ◽  
Vol 8 (43) ◽  
pp. 9881-9887
Author(s):  
Li Wang ◽  
Si-Min Xu ◽  
Shanyue Guan ◽  
Xiaozhong Qu ◽  
Geoffrey I. N. Waterhouse ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Cancer Diagnosis ◽  
Near Infrared ◽  
Photothermal Conversion ◽  
Diagnosis And Therapy ◽  
Photothermal Heating ◽  
Main Emphasis ◽  
Edge Defects ◽  
Cancer Diagnosis And Therapy ◽  
Conversion Efficiencies

Quantum dots (QDs) are increasingly being utilized as near infrared (NIR) active photothermal agents for cancer diagnosis and therapy, with the main emphasis of current research being the enhancement of photothermal conversion efficiencies.

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