scholarly journals Correlation of HbA1c levels with Triglyceride, LDL and HDL levels in Type 2 Diabetes Mellitus Patients

2021 ◽  
Vol 3 (2) ◽  
pp. 138-145
Author(s):  
Tri Prasetyorini ◽  
Cindy ◽  
Salbiah

Diabetes mellitus (DM) is a group of metabolic diseases with characteristics of increased blood glucose levels that occur due to abnormal insulin secretion, insulin action or both. It is necessary to monitor long-term glycemic status by measuring HbA1c levels to determine the quality of long-term blood glucose control. People with Type 2 DM are more at risk of suffering from cardiovascular disease characterized by dyslipidemia, with a characteristic description of high plasma triglyceride levels, elevated LDL levels and decreased HDL levels. The purpose of this study was to determine the relationship between HbA1c levels and levels of triglycerides, LDL and HDL. This study was an analytic observational study using a cross-sectional design. Data on each variable is secondary data obtained from patients with Type 2 DM at Jakarta Friendship Hospital for the period January-December 2018. The research sample used was 97 data of Type 2 DM patients. Chi-Square test showed an association between HbA1c levels and triglyceride levels with a value of p = 0.046 (< 0.05), there was a relationship between HbA1c levels and LDL levels with p = 0.742 (p > 0.05), and there was a relationship between HbA1c levels and HDL levels with p = 0.241 (p > 0.05). The conclusion obtained in this study is that there is a significant relationship between HbA1c levels and triglyceride levels and there was no significant relationship between HbA1c levels and LDL and HDL levels.

2018 ◽  
Vol 6 (1) ◽  
pp. 85
Author(s):  
Gema Akbar Wakhidana ◽  
Ancah Caesarina Novi Marchianti ◽  
Ali Santosa

Diabetes mellitus is metabolic diseases characterized by hyperglycemia caused by disturbances in insulin secretion or insulin activity. Herbal Forte Rice is rice synthetic material composed of main purple sweet potato and corn flour. It contains antioksidan, fiber, resistant starch and having moderate glycemic index. This study aimed to determine the effectivity of Herbal Forte Rice on decreasing blood glucose levels of patients type 2 DM. It used a cross-over design, the role of research subjects was both as control and treatment groups. Total sample of this research consisted of 60 samples. The treatment group was given Herbal Forte Rice for 7 days in 2 consecutive meals, while the control group did not receive any intervention. The results showed the average level of Fasting Blood Glucose (FBG) beginning and end of the treatment group 179.76 mg/dL and 138.7 mg/dL; FBG beginning and end of the control 180.87 mg/dL and 187.63 mg/dL; 2 hours post prandial Blood Glucose (2hppBG) levels of beginning and end of the treatment group 284.37 mg/dL and 183.8 mg/dL; 2hppBG levels beginning and end of the control 280.57 mg/dL and 284.13 mg/dL. This study concludes that Herbal Forte Rice effective on decreasing blood glucose levels of patients type 2 DM.   Keywords: diabetes mellitus, Rice Herbal Forte, GDP and GD2PP  


2019 ◽  
Vol 35 (4) ◽  
Author(s):  
Nazan Erenoglu Son

Objective: Diabetes Mellitus (DM) is a significant public health issue worldwide due to the associated comorbidities. Recent studies have demonstrated a strong relationship between blood glucose levels and serum ferritin levels in patients with type 2 DM. The aim of the study was to investigate the association between Ferritin Levels and Inflammatory Markers on HbA1c in the Type 2 Diabetes Mellitus Patients. Methods: This single-center, cross-sectional, controlled study included patients who were admitted to the Endocrine and Metabolic Disorders outpatient clinics of the Private Kütahya Hospital in the province of Kutahya in the Western Turkey. The study included a total of 172 patients, 84 of whom had type 2 DM and 88 without diabetes and constituted the control group. A total of 190 patients with DM were admitted to the Adult Endocrine and Metabolic Diseases Outpatient Clinics of the hospital between July 1, 2018 and September 1, 2018, and among these, the study was conducted on 172 volunteer patients who met the study inclusion criteria and who did not have any missing data. The HbA1c levels, serum ferritin, hemoglobin (Hb), insulin, Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), C-Reactive Protein (CRP), lipid profiles, and uric acid levels were compared between the groups. Results: The serum ferritin levels of the patients with type 2 DM significantly increased with increasing HbA1c levels (p<0.01). A strong positive correlation was found between serum ferritin levels and HbA1c and fasting blood glucose (FBG) levels (p<0.01). Conclusions: Our study results show a significant relationship between HbA1c levels and serum ferritin and CRP levels, suggesting that serum ferritin and CRP levels can be used as a routine screening tool for the early diagnosis of DM. However, further large-scale, prospective studies are needed to confirm these findings. doi: https://doi.org/10.12669/pjms.35.4.1003 How to cite this:Son NE. Influence of ferritin levels and inflammatory markers on HbA1c in the Type 2 Diabetes mellitus patients. Pak J Med Sci. 2019;35(4):---------. doi: https://doi.org/10.12669/pjms.35.4.1003 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2020 ◽  
Vol 1 (1) ◽  
pp. 51-60
Author(s):  
Maria Meilina Ekasari ◽  
Ana Setiyorini

Background: Diabetes Mellitus (DM) is a metabolic disorder caused by a reduction or absence of the insulin hormone from pancreatic beta cells, or due to impaired insulin function, or both. If the DM not managed properly can lead several of chronic disease. The education program for type 2 DM patients had been done by nurses, dietitians and doctors in outpatient department, but the quality of implementation has not been discovered. Objective: To describe the implementation of the blood glucose control health education program in patients with type 2 diabetes mellitus from the preinteraction phase to the termination phase at outpatient department in a privatehospital Yogyakarta. Methods: An observational quantitative research conducted from March to May 2019 in outpatient department in a private hospital Yogyakarta. Thirty respondents were recruit with accidental sampling technique. The inclusion criteria was nurses who provide health education to patients with type 2 DM. The observation performed during the health education session. Univariate analysis used to analysis the data. The distribution of data presented in frequency and percentage. Results: The majority of respondents (n=25; 83%) performed well, a small proportion of respondent (n=5; 17%) performed pretty good when deliver the blood sugar control health education in patients with type 2 DM from the preinteraction phase to the termination phase. Conclusion: It is necessary to improve the ability of nurses in conducting health education in patients by using standard operating procedures and conducting review of operational standard procedures.     Keywords: type 2 DM, health education, blood glucose control


Author(s):  
Mariaman Tjendera ◽  
Luis Yulia

Work Shift and HbA1C Levels are part of health science, occupational safety, and internal medicine. The incidence of type II diabetes mellitus in Batam ranks lasts 10 most suffered. The number of type II diabetes mellitus patients at Camatha Sahidya Hospital was 1188 in 2014, and 315 in January to June. This research method was observational analytic with a cross-sectional approach conducted at Camatha Sahidya Hospital, Batam City. The sampling technique was accidental sampling with populations in November and December unknown, determining a minimum sample using the Lemeshow formula obtained a minimum sample of 97 people. The results of the study were analyzed by cross-tabulated frequency distribution and then tested by the Chi-square test. The results of this study found that type 2 HR patients with work shifts were 38 people (39.2%) while 59 people working in non-shift systems (60.8%). HbA1c laboratory examination results of DM patients with HbA1c> 8% more than the amount of HbA1c ≤8%, as many as 54 people (55.7%) type 2 DM patients with a total HbA1c> 8% and 43 people (44.3% ) Type 2 DM patients with HbA1c count ≤8%. There is a significant relationship between work shifts with HbA1c levels in type 2 DM patients at the Camatha Sahidya Hospital in Batam City in 2018 using the Chi-Square statistical test obtained p-value = 0.014 (p <0.05). Based on this study it can be concluded that there is a significant relationship between work shifts with HbA1C levels in type 2 DM patients at Camatha Sahidya Hospital, Batam City.


2010 ◽  
Vol 7 (1) ◽  
pp. 83 ◽  
Author(s):  
Hiroyuki Ito ◽  
Hidenori Ishida ◽  
Yuichiro Takeuchi ◽  
Shinichi Antoku ◽  
Mariko Abe ◽  
...  

2020 ◽  
Vol 9 (1) ◽  
pp. BC01-BC03
Author(s):  
Ajay Puri ◽  
Jyoti Kohli ◽  
V.J. Chrunjoo

Background: Protein glycation is a spontaneous reaction that is believed to play a key role in the pathogenesis of many clinical disorders. The glycation of proteins is enhanced by elevated blood glucose concentrations. The major form of protein glycation with a clinical consideration is glycatedhaemoglobin (HbA1c). HbA1c is majorly affected by the blood glucose levels alone. Diabetes mellitus is a metabolic disorder characterized by hyperglycemia. Studies have suggested that HbA1c levels in type-2 diabetes mellitus patients mostly remains elevated, yet some such patients, with or without tight glycemic control, have HbA1c levels nearly close to or within the normal reference range.Subjects and Methods:In this study HbA1c, fasting blood glucose levels and post prandial blood glucose levels in normal subjects as well as in patients with Type-2 diabetes mellitus excluding the complicated ones were studied.Results:The present study confirms earlier studies that all these levels are tightly correlated and the corresponding p values were < 0.001 which were significant and was estimated by using student t-test.Conclusion: Thus indicating that glycated hemoglobin (HbA1c) can be used to assess the glycemic status of an individual for attaining the treatment goal of preventing long term complications of diabetes mellitus.


Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Linda G Mellbin ◽  
Klas Malmberg ◽  
Anders Waldenstrom ◽  
Hans Wedel ◽  
Lars Ryden

Aims Tight, insulin-based glucose control is recommended to diabetic patients (DM pat) with acute myocardial infarction (AMI). A potential draw-back would be if insulin induced hypoglycaemia (HG) had a negative impact of future prognosis. Methods 1253 pat (mean age 68 years; 67% males) with type 2 DM and suspect AMI were followed for a median of 2.1 years. 947 were randomised to insulin infusion during at least 24 hours while 306 were treated routinely. HG (blood glucose<3.0 mmol/L with or without symptoms) was recorded during hospitalisation. Unadjusted and adjusted (age, sex, smoking, previous MI and heart failure, renal function, duration of DM, coronary interventions, blood glucose at randomisation) Hazard Ratios (HR) and 95% Confidence Intervals (CI) for cardiovascular events (CVE = death, MI or stroke) during follow up were calculated. Results 153 pat (12.2%) experienced HG. During the first 24 hours 111 (11.7%) insulin-treated pat experienced HG (symptomatic 23.4%) compared with 3 (1.0%) pat on routine treatment (symptomatic 33.3%). As outlined in the figure HG was not an independent predictor of subsequent CVE. Conclusion Insulin induced HG was not a significant risk factor for subsequent CVE in AMI-pat with type 2 DM. Hypoglycaemic seem to identify patients at high risk for other reasons.


Sign in / Sign up

Export Citation Format

Share Document