scholarly journals Results of quantitative and qualitative analyses of traditional prescription “Lonlunsemberu-13”

2020 ◽  
pp. 31-38
Author(s):  
Nyamdemberel Tsagaanbaatar ◽  
Chimedragchaa Chimedtseren
Keyword(s):  
Phenolic Compounds ◽  
Spectrophotometric Method ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Total Phenolic ◽  
Total Phenolic Compounds ◽  
Primary Research ◽  
Traditional Mongolian Medicine ◽  
Active Substances ◽  
Qualitative Analyses

Traditional prescription Lonlunsemberu-13 has been widely used in traditional Mongolian medicine to treat gastro intestinal dyspepsia. The purpose of this study was to determine biologically active substances in the Traditional prescription Lonlunsemberu-13 as a primary research. We screened for phenolic compounds, flavonoids, coumarins and alkaloids using a TLC method, and then we have determined those biologically active substances content by the UV/Vis spectrophotometric method. We identified the gallic acid, rutin, quercetin, apigenin, luteolin, isofraxidin and piperine in the traditional prescription. The result revealed that “Lonlunsemberu-13” consisted 4.38% ±1.9 of total phenolic compounds, 0.63% ±0.17 flavonoids, 2.45% ±0.28 of coumarins and 0.83% ±0.064 alkaloids.

scholarly journals INHIBITION OF PHOSPHATIDYLCHOLINE LIPOSOMES OXIDATION BY PHENOLIC COMPOUNDS OF ALOE EXTRACTS: A. ARBORESCENS, A. PILLANSII AND A. SQUARROSA

2019 ◽  
pp. 83-90 ◽  
Author(s):  
Natalia Nikolaevna Sazhina ◽  
Petr Vladimirovich Lapshin ◽  
Natal'ya Viktorovna Zagoskina ◽  
Nadezhda Pavlovna Palmina
Keyword(s):  
Phenolic Compounds ◽  
Biological Activities ◽  
Total Content ◽  
Biological Properties ◽  
Biologically Active ◽  
Total Phenolic ◽  
Total Phenolic Compounds ◽  
Phosphatidylcholine Liposomes ◽  
Antioxidant Profile ◽  
Active Substances

Various species of the genus Aloe which there are in the world more than 500 are considered as important sources of biologically active substances and attract an attention of researchers by numerous manifestations of their biological properties. The most studied and used Aloe species are A. arborescens and A. vera, however some other species show not smaller biological activity, in particular antioxidant, than made mention. In the present work on model of the initiated oxidation of phosphatidylcholine liposomes comparison of the antioxidant activity (AOA) of leaves extracts of A. arborescens, A. pillansii, A. squarrosa and also the total content of their phenolic compounds was carried out. It is established that A. pillansii extract has approximately by 12 times higher AOA, than A. arborescens extract, and by 4 times, than A. squarrosa. The measured values of the total phenolic compounds content showed considerably smaller difference between these extracts. It can demonstrate existence in A. pillansii leaves of more difficult antioxidant profile, than in A. arborescens, and higher concentration of active phenolic metabolites. Results of this work allow recommending A. pillansii for more depth studies of its different biological activities.

scholarly journals COMPOSITION OF BIOLOGICALLY ACTIVE SUBSTANCES OF THE HORSE CHESTNUT (AECULUS HIPPOCASTANUM L.)

ÈKOBIOTEH ◽  
2021 ◽  
Vol 4 (1) ◽  
pp. 33-39
Author(s):  
V.P. Kurchenko ◽  
◽  
N.V. Sushinskaya ◽  
K.I. Maiorava ◽  
E.I. Tarun ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Antioxidant Activity ◽  
Phenolic Compounds ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Horse Chestnut ◽  
Hazard Class ◽  
Active Substances

The study of the composition of biologically active substances, alcoholic extracts from flowers of Aeculus hippocastanum L. According to the results of HPLC-MS and GC-MS analyzes, the extract contains the main amounts of phenolic compounds: quercetin, epicatechin, kaempferol. In addition, the extract contains fatty acids and their esters, alcohols, 3-deoxy-d-manno lactone, 1,2,3,5-cyclohexantethrol, α-methyl-mannofuranoside, γ sitosterol. Antioxidant activity of an extract from flowers of A. hippocastanum is associated with the peculiarities of the compositionof biologically active substances. The toxological-hygienic assessment of flowers of this species in acute and subacute experiments showed that it belongs to the 4th hazard class (low hazard).

scholarly journals Red Wine and Yacon as a Source of Bioactive Compounds with Antidiabetic and Antioxidant Potential

2020 ◽  
Author(s):  
Mariia Nagalievska ◽  
Mariya Sabadashka ◽  
Nataliia Sybirna
Keyword(s):  
Phenolic Compounds ◽  
Red Wine ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Low Grade ◽  
Smallanthus Sonchifolius ◽  
Grape Wine ◽  
Low Grade Inflammation ◽  
Antioxidant Effects ◽  
Active Substances

Phytochemicals derived from different plants are promising therapeutic agents. Herbal compounds can be used under diseases, etiological causes of which are alterations of carbohydrate, protein, and lipid metabolisms, along with increased oxidative stress and chronic low-grade inflammation. Potential sources of biologically active substances may be grape wine, rich in phenolic compounds. Well-studied examples of polyphenols are phenolic acids, catechins, anthocyanins, and flavonoids, etc. Another source of biologically active compounds is yacon (Smallanthus sonchifolius Poepp. & Endl.). The aboveground part of yacon is rich in phenolic compounds and terpenes. Main biologically active substances from tuberous roots of yacon are fructooligosaccharides and phenolic compounds. The section will be devoted to the analysis of hypoglycemic and antioxidant effects, and molecular targets of the complex of biologically active substances derived from red wine and yacon.

scholarly journals Optimization of parameters of the extraction process of biologically active substances of grass Adonis vernalis

2021 ◽  
Vol 3 (3(59)) ◽  
pp. 14-18
Author(s):  
Anna Krvavych ◽  
Roksolana Konechna
Keyword(s):  
Phenolic Compounds ◽  
Extraction Method ◽  
Cardiac Glycosides ◽  
Maximum Yield ◽  
Particle Diameter ◽  
Cardiac Activity ◽  
Value Added ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Active Substances

The object of this research is the herb Adonis vernalis and hydroalcoholic extracts obtained on its basis. By the nature of the action, the drugs Adonis vernalis belong to the group of cardiac glycosides and occupy an intermediate place between strophanthin and digitalis. In official medicine, biologically active compounds of Adonis vernalis are included in drugs such as Cardiovalen, Adonis-bromine, Caridiolin and Cardiophyte. In the extemporal formulation, the extract is part of the Bechterew’s medicine. Until recently, scientists have made significant progress in studying the phytochemical and pharmacological action of the herb Adonis vernalis. However, one should not be limited to the use of Adonis vernalis only for stimulating cardiac activity, one should also consider the promising antioxidant effect of flavonoids and phenolic compounds that are contained in this medicinal plant. Also, studies of the extraction conditions of the herb Adonis vernalis are not described in the scientific literature. The study carried out the extraction of the grass Adonis vernalis by various methods (static and dynamic). The type of extract was chosen as the most rational, which provides the maximum yield of extractives (phenolic compounds and cardiac glycosides). For this, the optimal extraction conditions were selected, namely, the particle size, the type of extractant, the value of the hydromodule and the extraction method. Accordingly, the optimal particle diameter for maximum extraction of biologically active substances of the herb Adonis vernalis is 2.5 mm, the optimal extractant is 70 % ethyl alcohol, the ratio of raw materials: extractant is 1:10, the optimal extraction method is maceration with constant stirring. Phytochemical studies of the quantitative composition of the main groups of biologically active substances were carried out using calorimetric and spectrophotometric methods of analysis. As a result of the optimization of the process and its introduction into production on an industrial scale, the value added effect will be achieved. And also a high-quality product has been created that will compete with broad-spectrum drugs already existing on the market.

scholarly journals Contents of dry matter, soluble sol­ids, vitamin C and phenolic compounds in the pulp and peel of different cultivars of pear fruits

2021 ◽  
Vol 28 (2) ◽  
Author(s):  
Jaunė Blažytė ◽  
Nijolė Vaitkevičienė
Keyword(s):  
Phenolic Compounds ◽  
Vitamin C ◽  
Dry Matter ◽  
Total Content ◽  
Biologically Active ◽  
Soluble Solids ◽  
Total Phenolic ◽  
Total Phenolic Compounds ◽  
Pear Fruit ◽  
Fruit Peel

The aim of this work was to investigate and compare the amounts of biologically active compounds, dry matter and soluble solids in pulp and peels of four pear cultivars (‘Ksena’, ‘Beloruskaja pozdniaja’, ‘Alna’ and ‘Aleksandr Lucas’). The research was carried out at Vytautas Magnus University Agriculture Academy (Lithuania) in 2020. Four pear cultivars (‘Ksena’, ‘Beloruskaja pozdniaja’, ‘Alna’ and ‘Aleksandr Lucas’) were cultivated at a farm in the Joniškis District of Lithuania. Pears were grown following traditional pear production technology. The amounts of dry matter, soluble solids, vitamin C and fiber were determined using the standard method. The total content of phenolic compounds was determined using a Folin-Ciocalteu reagent with a UV/VIS spectrophotometer. The research results showed that significantly the highest amounts of soluble solids were found in the ‘Alna’ pear fruit pulp (14.25% f. w.). The ‘Alna’ peel sample had significantly the highest amount of total phenolic compounds (1290.99 mg 100 g–1 d. w.). The highest content of dry matter was found in the ‘Aleksandr Lucas’ pear fruit peel (24.67%). The ‘Aleksandr Lucas’ and ‘Beloruskaja pozdniaja’ pear fruit peel contained significantly the highest amounts of vitamin C (2.70 and 2.63 mg 100 g–1 f. w., respectively). The highest content of fiber was found in the ‘Ksena’ fruit peel (36.12% d. w.). The investigated pear peel sample had significantly higher amounts of dry matter, vitamin C, total phenolic compounds and fiber than the pulp. However, the pulp contains the highest contents of soluble solids.

scholarly journals Research of biologically active compounds of catalpa (Catalpa bignonioides Walt.)

2020 ◽  
pp. 52-58
Author(s):  
O. V. Demeshko ◽  
S. V. Romanova ◽  
V. V. Kovalyov ◽  
I. I. Batiuchenko
Keyword(s):  
Acetic Acid ◽  
Phenolic Compounds ◽  
Chromatographic Analysis ◽  
Skin Diseases ◽  
Biologically Active Compounds ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Active Compounds ◽  
Chromatographic Paper ◽  
Active Substances

Catalpa bignonioides Walt. (catalpa) the family Bignoniaceae – a tree, which originates from North America. Catalpa bark contains resins and tannins. Monoterpene glycosides were found in the leaf. Catalpa seeds contain up to 30% of eleostearic acid. Decoctions are made of the bark of the tree. They serve as a gastric agent and have an anthelmintic effect. Decoction of the bark exhibits bronchodilator action, is used in the complex treatment of cancer. The leaves are used to treat skin diseases. The infusion of fruits has anti-herpetic and hypoglycemic properties. The aim of the work is to investigate biologically active compounds of the leaves of catalpa bignini. The object of the study was the leaves of common catalpa harvested in the summer of 2018 in Sevastopol. Chemical identification reactions and methods of chromatographic analysis were used to determine the major groups of biologically active substances of the leaves of the catalpa (chromatographic paper Filtrak FN No. 4, Munktell, Czech Republic). Chromatography was performed in pre-selected solvent systems: n-butanol‒acetic acid‒water (BAW) (4:1:2) ‒ I direction and 15% acetic acid ‒ II direction. Identification reactions were performed with aqueous and aqueous-alcoholic extracts of catalpa leaves. The qualitative composition of the phenolic compounds was investigated by paper chromatography. The content of the sum of phenolic compounds, hydroxycyclic acids and flavonoids was determined by the spectrophotometric method. Based on the held reactions and chromatographic analysis, by the characteristic fluorescence in the filtered UV light before and after treatment with chromogenic reagents and the values of Rf in the raw material the presence of the following groups of biologically active substances were determined: flavonoids, phenol glycosides, hydroxycoric acids. According to the chromatographic analysis, at least 9 substances of phenolic nature have been detected in the alcohol-aqueous extracts. For the first time, the presence of the following groups of biologically active substances: hydroxycoric acids, phenologic glycosides, flavonoids was determined in the leaves of catalpa. Quantitative content of natural compounds in the leaves of common catalpa: the sum of phenolic compounds (4,76 ± 0,04%), of hydroxycoric acids (3,42 ± 0,02%), of flavonoids (1,88 ± 0,02%). The results of the study will be used in the development of the draft quality control methods for medicinal plant raw materials.

Micellar-mediated extraction of green tea containing Chrysanthemum morifolium flowers

2017 ◽  
Vol 1 (1) ◽  
pp. 49-52 ◽  
Author(s):  
Justyna Suliga ◽  
Paweł Śliwa
Keyword(s):  
Fatty Acids ◽  
Phenolic Compounds ◽  
Green Tea ◽  
Plant Material ◽  
Chrysanthemum Morifolium ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Tween 20 ◽  
Sorbitan Esters ◽  
Active Substances

Micellar mediated extraction (MME) is a new and alternative method of obtaining biologically active substances, such as flavones, flavanones, anthocyanins, triterpene from plant material. In this study a series of polyethoxylated sorbitan esters of fatty acids (Tween 20, 40, 60 and 80) have been applied for the extraction of green tea containing Chrysanthemum morifolium flowers. Results showed that all tested surfactants were effective in the solubilisation of flavonoids and phenolic compounds. Probably, because of too high hydrophilicity, Tween 20 was not sufficient to obtain antioxidants, in contrast to another Tween. It has been shown that method is economical, attractive and ecological.

scholarly journals Characterization of Moravian Wines by Selected Chemical Parameters

Separations ◽  
2021 ◽  
Vol 8 (7) ◽  
pp. 89
Author(s):  
Jan Javorský ◽  
Martin Král ◽  
Marek Šnirc ◽  
Július Árvay ◽  
Bohuslava Tremlová ◽  
...  
Keyword(s):  
Titratable Acidity ◽  
Grape Pomace ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Total Phenolic ◽  
Wine Production ◽  
Bottle Aging ◽  
The Subject ◽  
Active Substances

Knowledge of analytical values in wines is essential to ensure product safety and compliance with legislation, and it is also essential to understand the various technologies in wine production. The aim of this work was to evaluate the analytical parameters of bottled Moravian wines from the Znojmo sub-region, from harvests 2015 and 2016. Basic oenological parameters and biologically active substances were evaluated. Moreover, we evaluated conditions during bottle aging in wines from harvest 2016. The results of the basic analytical values such as total phenolic acid (TPA), total sulfur dioxide (SO2), pH, actual alcohol content (EtOH), and titratable acidity (TA) were in accordance with generally known values in wines and met the legislative requirements within oenological practices. Biologically active substances, such as gallic acid, trans-caffeic acid (TCA), trans-p-coumaric acid (TPCA), rutin, ferulic acid (FA), myricetin, resveratrol, and quercetin were identified. Comparing the analytical values of individual types of wine leads to a better understanding of winemaking technology and the development of wine as such. The subject of the study was also the monitoring of produced grape pomace incurred during wine production harvest 2015 with the indication of possibilities of its further use.

scholarly journals Comparative study of phenolic compounds of the herb of Betonica L. genus species of flora of Ukraine

2021 ◽  
pp. 66-75
Author(s):  
Iryna Sas ◽  
Andrii Hrytsyk ◽  
Taras Koliadzhyn ◽  
Oleh Koshovyi
Keyword(s):  
Phenolic Compounds ◽  
Comparative Study ◽  
Hydroxycinnamic Acids ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
New Drugs ◽  
Raw Material ◽  
Wide Range ◽  
Nitrogen Containing Compounds ◽  
Active Substances

Species of Betonica L. genus are widespread in Ukraine and contain different groups of biologically active substances: hydroxycinnamic acids, flavonoids, tannins, iridoids, terpenoids, steroids, essential oil, organic acids, vitamin K, nitrogen-containing compounds, phenylethanoid glycosides. Species of Betonica L. genus show a wide range of pharmacological activity (anti-inflammatory, antioxidant, choleretic, diuretic, sedative, antitumor, antihypertensive, etc.) and phenolic compounds are one of the most important and promising groups of biologically active substances of these plants. The aim. The aim of the work was to conduct a comparative study of the phenolic compounds of the herb of Betonica L. genus species of flora of Ukraine. Materials and methods. The object of the study was the herb of Betonica peraucta and Betonica brachydonta harvested in the phase of mass flowering of the plant in Ivano-Frankivsk region. The study of phenolic compounds was carried out by paper chromatography, HPLC and spectrophotometry. Results. 7 components of tannins, 4 flavonoids, 5 hydroxycinnamic acids, 2 coumarins were identified and quantified by HPLC in the studied raw material. The quantitative content of the main groups of phenolic compounds in the herb of Betonica peraucta and Betonica brachydonta was determined by the method of absorption spectrophotometry: polyphenols – 5.96 % and 4.82 %, tannins – 1.62 % and 0.68 %, flavonoids – 2.07 % and 1.13 %, hydroxycinnamic acids – 7.01 % and 3.58 %, respectively. Conclusions. As a result of the conducted studies it was found that the content of phenolic compounds in the herb of Betonica peraucta is significantly higher than in the herb of Betonica brachydonta. Therefore, this species is promising for further research and creation of new drugs

scholarly journals EDIBLE ONION FLOWERS (ALLIUM L.) AS A SOURCE OF BIOLOGICALLY ACTIVE SUBSTANCES

2021 ◽  
pp. 291-297
Author(s):  
Tat'yana Ivanovna Fomina ◽  
Tat'yana Abdulkhailovna Kukushkina
Keyword(s):  
Phenolic Compounds ◽  
Raw Materials ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Raw Material ◽  
Forest Steppe ◽  
Dry Matter Content ◽  
Total Sugars ◽  
Active Substances ◽  
Pectin Substances

The results of comparative study of the content of biologically active substances in the flowers of 10 species of perennial onions Allium aflatunense B. Fedtsch., A. altaicum Pall., A. flavum L., A. microdictyon Prokh., A. nutans L., A. obliquum L., A. ramosum L., A. rosenbachianum Regel, A. schoenoprasum L., A. senescens L. var. glaucum Regel (A. senescens ssp. glaucum (Schrad.) N. Friesen) are presented. The freshly collected raw materials in the phase of mass flowering were analyzed. The dry matter content was determined by drying 1 g of raw material at 100–105 °C to a constant mass. The amount of phenolic compounds, pectin substances, total sugars, and carotenoids was determined spectrophotometrically using SF-56 (Russia) and SF "Agilent" 8453 (USA). For the first time, data on the quantitative content of the main groups of secondary metabolites in onion flowers were obtained. It has been established that in the forest-steppe of Western Siberia, flowers of Allium species contain: 10.7-22.5% dry substances, 6.6-26.2% total sugars, 3.3–18.6% pectin substances, 3.6–10.6% phenolic compounds, 3.0–23.4  mg% carotenoids (per mass of absolutely dry materials) and 35.4–157.8 mg% ascorbic acid (per mass of raw materials). The highest values were found for A. rosenbachianum, A. flavum, and A. aflatunense. The high variability of the accumulation of biologically active substances is due to the species and the influence of weather conditions during the growing season. The study showed the prospects for using onion flowers as a source of various bioactive compounds, including when added to food.

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