scholarly journals Functional capacity and risk of falls in the elderly with metabolic syndrome

2020 ◽  
Vol 15 (42) ◽  
pp. 2228
Author(s):  
Ramon Repolês Soares ◽  
Patrícia de Oliveira Salgado ◽  
Kelvin Oliveira Rocha ◽  
Luciana Moreira Lima

Introduction: Metabolic syndrome (MetS) is the most common metabolic abnormality in the population that predisposes to cardiovascular events and may be related to poor physical fitness and low functional capacity in the elderly. The objective of this study was to evaluate the interference of metabolic changes in functional capacity and risk of falls in the elderly. Methods: A cross-sectional study was carried out with 126 elderly subjects, 58 presented MetS and 68 without MetS, according to the criteria of the International Diabetes Federation. Katz Index, Tinetti Index, Timed Up and Go test and Berg Scale were applied to evaluate the functional capacity. Falls Efficacy Scale-International scale (FES-I-Brazil) was used to evaluate the fear of falling. For statistical analysis, the Mann-Whitney, Chi-square and Spearman correlation tests were used. Results: There was an association between the MetS and non-MetS groups in relation to the risk strata of the TUG index [p=0.02; OR=0.38; 95%CI (0.16-0.91)]. Between these two groups, there was a significant difference in the mean of the following markers: Berg scale (p=0.03); TUG (p=0.03); FES-I-Brazil (p=0.02). The Kats and IPAQ index did not show any significant association. Conclusions: Elderly patients with MetS presented higher risk and fear of falls when compared to patients without MetS. However, there was no variation in walking ability or balance.

2020 ◽  
Vol 4 (3) ◽  
pp. 191
Author(s):  
Rendi Aji Prihaningtyas ◽  
Nur Aisiyah Widjaja ◽  
Meta Herdiana Hanindita ◽  
Roedi Irawan

ABSTRACTBackground : The prevalence of obesity in adolescents is increasing and causes metabolic syndrome at a young age. Metabolic syndrome results from the interaction of environmental, genetic, and dietary factors. The purpose of this study was to determine the diet profile of obese adolescents suffering from metabolic syndrome.Methods: This study was a cross-sectional study of obese adolescents who visited the Pediatric Nutrition and Metabolic Disease in Dr. Soetomo General Hospital, Surabaya. The anthropometry examination (weight, height and waist circumference), blood pressure, and blood tests (HDL cholesterol, triglycerides and blood glucose levels) were measured. The diagnosis of metabolic syndrome was based on the International Diabetes Federation. Food consumption data was obtained through direct interviews using data collection sheets. Analysis of dietary differences in obese adolescents suffering from metabolic syndrome was performed by chi square using SPSS.Results and Discussions: A total of 59 obese adolescents aged 13-16 years were involved in this study. A total of 27 subjects (45.8%) suffered from metabolic syndrome and 32 subjects (54.2%) did not suffer from metabolic syndrome. The level of the consumption of fish, vegetables, and fruit in obese adolescents were still low. There was no significant difference in the diet profile between obese adolescents who suffer from metabolic syndrome or not.Conclusion: Prevention strategies through food consumption patterns are needed in obese adolescents to control metabolic stress processes and prevent metabolic syndrome in the future. Diet knowledge in obese adolescents needs to be given early to prevent further complications. Increasing foods that contain anti-oxidants, such as fruits and vegetables, is one of the strategies to prevent metabolic syndrome in obese adolescents.ABSTRAKLatar Belakang : Prevalensi obesitas pada remaja semakin meningkat dan menyebabkan sindrom metabolik di usia muda. Sindrom metabolik terjadi akibat interaksi faktor lingkungan, genetik, dan diet. Tujuan dari penelitian ini adalah mengetahui profil diet pada remaja obesitas yang menderita sindrom metabolik.Metode : Penelitian ini merupakan penelitian potong lintang pada remaja obesitas yang berkunjung di Poli Nutrisi dan Penyakit Metabolik Anak di RSUD Dr. Soetomo, Surabaya. Pada subyek dilakukan pemeriksaan antropometri (berat badan, tinggi badan, dan lingkar pinggang), pemeriksaan tekanan darah, dan pemeriksaan darah (kolesterol HDL, trigliserida, dan kadar glukosa darah). Diagnosis sindrom metabolik ditegakkan berdasarkan International Diabetes Federation. Data konsumsi makanan didapatkan melalui wawancara langsung dengan menggunakan lembar pengumpul data. Analisis perbedaan diet pada remaja obesitas yang menderita sindrom metabolik dilakukan dengan chi square menggunakan SPSS.Hasil dan Pembahasan : Sebanyak 59 remaja obesitas yang berusia 13-16 tahun terlibat dalam penelitian ini. Sebanyak 27 subyek (45,8%) menderita sindrom metabolik dan sebanyak 32 subyek (54,2%) tidak menderita sindrom metabolik. Tingkat konsumsi ikan, sayur, dan buah pada remaja obesitas masih rendah. Tidak ada perbedaan yang bermakna pada profil diet antara remaja obesitas yang menderita sindrom metabolik maupun tidak.Kesimpulan : Strategi pencegahan melalui pola konsumsi makanan diperlukan pada remaja obesitas untuk mengontrol proses stres metabolik sehingga dapat mencegah sindrom metabolik di masa datang. Pengetahuan diet pada remaja obesitas perlu diberikan sejak dini untuk mencegah komplikasi lebih lanjut. Memperbanyak makanan yang mengandung anti-oksidan, seperti buah dan sayur merupakan salah satu strategi mencegah sindrom metabolik pada remaja obesitas.


2010 ◽  
Vol 68 (1) ◽  
pp. 39-43 ◽  
Author(s):  
Gilson de Vasconcelos Torres ◽  
Luciana Araújo dos Reis ◽  
Luana Araújo dos Reis

OBJECTIVE: To assess the functional capacity and to determine the difference between the means of functional capacity (basic and instrumental activities of daily living) and the age groups of elderly residents in an outlying area in the hinterland of Bahia/Northeast of Brazil. METHOD: Analytical study with cross-sectional design and a sample of 150 elderly individuals enrolled in four Health Units in the municipality of Jequié, Bahia, Brazil. The instrument consisted of sociodemographic and health data, the Barthel Index and the Lawton scale. RESULTS: In all, 78.00% of the elderly were classified as dependent in the basic activities and 65.33% in the instrumental activities of daily living. Using the Kruskal-Wallis test, we found a statistically significant difference between the means of instrumental activities and the age groups (p=0.011). CONCLUSION: An elevated number of elderly were classified as dependent in terms of functional capacity and increased age is related to greater impairment in the execution of instrumental activities of daily living.


Author(s):  
Hudson Azevedo Pinheiro ◽  
Jaquelynne Dourado Mendes Brandão ◽  
Aline Laginestra e Silva

Abstract To evaluate functional capacity, mobility and balance in elderly patients with Alzheimer's Disease (AD), in its mild, moderate and severe forms, verifying the existence of correlation among these parameters. Eighty-eight elderly patients (81.79 ± 6.54 years) diagnosed with AD treated at an elderly care reference center in Taguatinga-DF were selected, and information was collected between November 2018 and March 2019. Data collection was initially made by filling in the evaluation form. Subsequently, two questionnaires were administered to caregivers (Clinical Dementia Rating-CDR and Disability Assessment for Dementia -DAD) and two tests to demented patients (Southampton Assessment of Mobility-SAM-Br and Timed Up and Go-TUG). Variables were correlated using the SPSS software version 22 using Pearson's correlation, with significance level p?0.05. The following results were obtained: 1. weak correlations between CDR and DAD (p = 0.04; r = -0.31) with significant difference; 2. strong correlation and significant difference between CDR and TUG (p = 0.02; r = 0.87); 3. weak and non-significant correlation between CDR and SAM-Br (p = 0.14; r = -0.24); 4. significant difference and highly strong correlation between SAM-Br and TUG (p = 0.01; r = 0.70). Older adults with Alzheimer's disease present decreased functional capacity, mobility and risk of falls associated with the disease progression. SAM-Br and TUG tools showed strong correlation and, although it is a generic measure, TUG showed strong correlation with AD progression, and may be a predictive test for the risk of falls in this population.


2018 ◽  
Vol 0 (0) ◽  
Author(s):  
Aleksandra Klisic ◽  
Nebojsa Kavaric ◽  
Ivan Soldatovic ◽  
Ana Ninic ◽  
Jelena Kotur-Stevuljevic

Abstract Background Retinol-binding protein 4 (RBP4) and cystatin C are regarded as novel metabolic risk markers. Therefore, we aimed to examine which one of these biomarkers better correlates with metabolic syndrome (MetS) in a cohort of postmenopausal women. Methods A total of 129 postmenopausal women (among which 62 women had MetS) were recruited in this cross-sectional study. MetS was diagnosed according to the International Diabetes Federation criteria. Results Cystatin C and RBP4 levels were significantly higher in women with MetS, compared to those without MetS (p=0.011 vs. p<0.001, respectively). A significant difference in the proportion of women with and without MetS across cystatin C and RBP4 quartiles was observed (χ2=5.1, p=0.025, and χ2=11.1, p=0.001, respectively). Logistic regression analysis revealed a borderline significant relationship between cystatin C and MetS (p=0.066), but this significance disappeared after adjustment for age, inflammation level and duration of menopause (p=0.221). On the contrary, a significant relationship between RBP4 and MetS was observed not only without adjustment (p=0.009), but also even after adjustment for age, inflammation level and duration of menopause (p=0.006). Conclusions RBP4 better correlates with MetS than cystatin C in postmenopausal women.


2017 ◽  
Vol 41 (S1) ◽  
pp. S168-S168
Author(s):  
A. Puangpetch ◽  
C. Na Nakorn ◽  
W. Unaharassamee ◽  
C. Sukasem

IntroductionMetabolic syndrome is a significant problem in the schizophrenia patients. Previous research demonstrated that single nucleotide polymorphisms in the serotonin 2C receptor (5HTR2C) genes are associated with metabolic syndrome related to schizophrenia patients taking atypical anti-psychotic drugs. This study aimed to investigate whether the effect of 3 SNPs in 5HTR2C gene on the presence of the metabolic syndrome in Thai schizophrenia patients.MethodWe conducted a cross-sectional study and 154 patients were recruited. The schizophrenia patients were identified from a diagnostic and statistical manual of mental disorders, 4th edition, (DSM-IV) and criterion and determined the metabolic syndrome according to the 2005 international diabetes federation (IDF) Asia criteria. Patients were genotyped for the 5HTR2C rs51,8147, rs126,881,02, rs128,367,71 polymorphisms.ResultsThe preliminary analysis from 154 patients showed the metabolic syndrome prevalence was 38.73%, with 46.50% in male and 53.48% in female patients. The results showed that the patients who have heterozygous and homozygous variant on 5HTR2C gene (rs518,147 and rs126,881,02) showed a significant difference in the presence of metabolic syndrome when compare with patients who carry homozygous wild type (P = 0.007), especially in male patients (P = 0.002). The association between 5HTR2C polymorphisms and metabolic syndrome was found in male patients but not found in female patients.ConclusionThese findings suggest that 5HTR2C genotypes are associated with the metabolic syndrome in patients taking atypical anti-psychotics. However, the metabolic syndrome results from the multigenetic effects. The further studies should focus on the other genes, which were involved in metabolic syndrome.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2017 ◽  
Vol 20 (6) ◽  
pp. 805-813 ◽  
Author(s):  
Luisa Veríssimo Pereira Sampaio ◽  
Leonardo Braga Castilho ◽  
Gustavo de Azevedo Carvalho

Abstract Objective: to develop an application for mobile devices to evaluate the balance and risk of falls of the elderly. Method: A cross-sectional study with a sample composed of 54 elderly individuals with an average age of 71 years submitted to three balance and risk of falls evaluation tests, was performed. The Timed Up and Go (TUG) and Performance Oriented Mobility Assessment (POMA) tests were employed. Results: The results were closely correlated, identifying three groups of volunteers: low, medium and high risk of falls. When these values were compared with the analyzes performed by the application, some of the variations in the results generated by the application were not related to the classic tests, as the software could discriminate between individuals with a high and low risk of falls. Conclusion: The developed application was able to verify the oscillations present in the maintenance of static balance of the elderly and could differentiate the results into two groups of high and low risk of falls.


2019 ◽  
Vol 43 (1) ◽  
pp. 29-34
Author(s):  
Aleksandra Klisic ◽  
Nebojsa Kavaric ◽  
Ivan Soldatovic ◽  
Ana Ninic ◽  
Jelena Kotur-Stevuljevic

Abstract Background Retinol-binding protein 4 (RBP4) and cystatin C are regarded as novel metabolic risk markers. Therefore, we aimed to examine which one of these biomarkers better correlates with metabolic syndrome (MetS) in a cohort of postmenopausal women. Methods A total of 129 postmenopausal women (among which 62 women had MetS) were recruited in this cross-sectional study. MetS was diagnosed according to the International Diabetes Federation criteria. Results Cystatin C and RBP4 levels were significantly higher in women with MetS, compared to those without MetS (p=0.011 vs. p<0.001, respectively). A significant difference in the proportion of women with and without MetS across cystatin C and RBP4 quartiles was observed (χ2=5.1, p=0.025, and χ2=11.1, p=0.001, respectively). Logistic regression analysis revealed a borderline significant relationship between cystatin C and MetS (p=0.066), but this significance disappeared after adjustment for age, inflammation level and duration of menopause (p=0.221). On the contrary, a significant relationship between RBP4 and MetS was observed not only without adjustment (p=0.009), but also even after adjustment for age, inflammation level and duration of menopause (p=0.006). Conclusions RBP4 better correlates with MetS than cystatin C in postmenopausal women.


Author(s):  
Isabela Feitosa de Carvalho ◽  
Gianluca Loyolla Montanari Leme ◽  
Marcos Eduardo Scheicher

Background: Postural balance consists of information emanating from the interaction of visual, somatosensory and vestibular systens. This information is impaired in aging, leading to postural control changes in the elderly, increasing the risk of falls in this population. The postural balance may be improved with the addition of sensory information, such as a subpatelar bandage. Objective: To investigate the effect of using additional sensory information in gait speed and functional mobility of older fallers. Methods: 28 elderly women were evaluated, all were considered fallers. The test Timed Up and Go (TUG) was used to assess functional mobility and 10m Test to evaluate the gait speed. The tests were performed with and without the addition of additional sensory information (subpatelar strip). The normality was verified by the Shapiro-Wilk test and the results were compared using paired Student t test and Wilcoxon test. Results: There was significant difference in the TUG (p = 0.0006) and in the gait speed (p = 0.004) with and without subpatelar strip. Conclusion: The use of additional sensory information increased the gait speed and functional mobility of older fallers.


2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Shuo Lin ◽  
Li Hu ◽  
Ping Li ◽  
Xiaofeng Li ◽  
Keyi Lin ◽  
...  

Aims. Whether neck circumference (NC) could be used as a valuable tool for identifying metabolic syndrome (MS) by different criteria in Chinese is still unclear. Methods. We conducted a cross-sectional survey from October 2010 to January 2011 in Shipai community, Guangzhou, Guangdong Province, China. A total of 1473 subjects aged over 50 years were investigated. We measured height, weight, NC, waist circumference, blood pressure, blood glucose, and lipids in all subjects. MS was identified by criteria of the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III), Chinese Diabetes Society (CDS), and International Diabetes Federation (IDF). Results. Mean NC was 38.0 ± 2.7 cm in men and 34.2 ± 2.5 cm in women. By using receiver operating characteristic curves, the area under the curve (AUC) of NC for identifying MS (IDF) was 0.823 in men and 0.777 in women, while for identifying MS (CDS), it was 0.788 in men and 0.762 in women. The AUC of NC for diagnosing MS (ATP III) was 0.776 in men and 0.752 in women. The optimal cut points of NC for MS were 38.5 cm by three definitions in men, while those were 34.2 cm, 33.4 cm, and 34.0 cm in women by IDF, ATP III, and CDS definitions, respectively. No significant difference was observed between the AUC of NC and BMI for diagnosing MS by using different criteria (all p>0.05). Conclusions. NC is associated with MS by different definitions in Chinese subjects over 50 years old. It may be a useful tool to identify MS in a community population.


Rev Rene ◽  
2020 ◽  
Vol 21 ◽  
pp. e43864
Author(s):  
Marilia Braga Marques ◽  
Janaína Fonseca Victor Coutinho ◽  
Caroline Ribeiro Sousa ◽  
Joana Maria Rocha Sales ◽  
Maria Lucimar Castro de Brito ◽  
...  

Objective: to analyze factors related to sarcopenia and functional capacity of institutionalized elderly. Methods: descriptive, correlational, cross-sectional study, with 92 elderly people, in four long-term institutions. For data collection, a socioeconomic and clinical form, Mini Mental State Examination, Barthel Index and Timed Up and Go test were applied. In the analysis, the chi-square and Fisher’s exact tests were adopted. Results: it was identified that 68 (73.9%) had probable sarcopenia, 7 (7.6%) sarcopenia and 11 (12.0%) severe sarcopenia. The factors associated with sarcopenia were education (p=0.017), risk of falls (p=0.000) and chronic kidney disease (p=0.040). As for functional capacity, 49 (53.3%) had mild dependence, 40 (43.5%) moderate and 3 (3.3%) severe. The factors associated with functional capacity were risk of falls (p=0.010), polypharmacy (p=0.017) and education (p=0.019). Conclusion: it was found that education, polypharmacy, chronic kidney disease, risk of falls, falls and sarcopenia can influence the functional capacity of institutionalized elderly.


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