Evaluation of nutritional composition, bioactive compounds and antimicrobial activity of Elaeocarpus serratus fruit extract

AbstractIn this study, the extraction conditions extracted maximize amounts of phenolic and bioactive compounds from the fruit extract of Ficus auriculata by using optimized response surface methodology. The antioxidant capacity was evaluated through the assay of radical scavenging ability on DPPH and ABTS as well as reducing power assays on total phenolic content (TPC). For the extraction purpose, the ultrasonic assisted extraction technique was employed. A second-order polynomial model satisfactorily fitted to the experimental findings concerning antioxidant activity (R2 = 0.968, P < 0.0001) and total phenolic content (R2 = 0.961, P < 0.0001), indicating a significant correlation between the experimental and expected value. The highest DPPH radical scavenging activity was achieved 85.20 ± 0.96% at the optimum extraction parameters of 52.5% ethanol (v/v), 40.0 °C temperature, and 22 min extraction time. Alternatively, the highest yield of total phenolic content was found 31.65 ± 0.94 mg GAE/g DF at the optimum extraction conditions. From the LC–ESI–MS profiling of the optimized extract, 18 bioactive compounds were tentatively identified, which may regulate the antioxidant activity of fruits of F. auriculata.

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Nutritional composition and bioactive compounds of Melipona seminigra pot‐pollen from Amazonas, Brazil

Journal of the Science of Food and Agriculture ◽

10.1002/jsfa.11125 ◽

2021 ◽

Author(s):

Kemilla Sarmento Rebelo ◽

Cinthia Baú Betim Cazarin ◽

Amadeu Hoshi Iglesias ◽

Marcella Aparecida Stahl ◽

Karsten Kristiansen ◽

...

Keyword(s):

Bioactive Compounds ◽

Nutritional Composition

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Antioxidant Effects of Schisandra chinensis Fruits and Their Active Constituents

Antioxidants ◽

10.3390/antiox10040620 ◽

2021 ◽

Vol 10 (4) ◽

pp. 620

Author(s):

Dalia M. Kopustinskiene ◽

Jurga Bernatoniene

Keyword(s):

Alternative Medicine ◽

Bioactive Compounds ◽

Antioxidant Activities ◽

Polyphenolic Compounds ◽

Schisandra Chinensis ◽

Aging Effects ◽

Fruit Extract ◽

Active Constituents ◽

Pathological Conditions ◽

Antioxidant Effects

Schisandra chinensis Turcz. (Baill.) fruits, their extracts, and bioactive compounds are used in alternative medicine as adaptogens and ergogens protecting against numerous neurological, cardiovascular, gastrointestinal, liver, and skin disorders. S. chinensis fruit extracts and their active compounds are potent antioxidants and mitoprotectors exerting anti-inflammatory, antiviral, anticancer, and anti-aging effects. S. chinensis polyphenolic compounds—flavonoids, phenolic acids and the major constituents dibenzocyclooctadiene lignans are responsible for the S. chinensis antioxidant activities. This review will focus on the direct and indirect antioxidant effects of S. chinensis fruit extract and its bioactive compounds in the cells during normal and pathological conditions.

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In vitro evaluation of antimicrobial activity and estimation of Epicatechin from the fruit extract of Prunus armeniaca L using HPTLC technique

International Journal of Pharmaceutical Research ◽

10.31838/ijpr/2020.12.04.562 ◽

2020 ◽

Vol 12 (04) ◽

Keyword(s):

Antimicrobial Activity ◽

Prunus Armeniaca ◽

Fruit Extract ◽

In Vitro Evaluation ◽

Prunus Armeniaca L

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Evaluation of antimicrobial, antioxidant and cytotoxic properties of bioactive compounds produced from endophytic fungi of Himalayan yew (Taxus wallichiana) in Nepal

F1000Research ◽

10.12688/f1000research.23250.1 ◽

2020 ◽

Vol 9 ◽

pp. 379 ◽

Cited By ~ 1

Author(s):

Dhurva Prasad Gauchan ◽

Pratistha Kandel ◽

Astha Tuladhar ◽

Ashesh Acharya ◽

Upendra Kadel ◽

...

Keyword(s):

Antimicrobial Activity ◽

Secondary Metabolites ◽

Ethyl Acetate ◽

Bioactive Compounds ◽

Endophytic Fungi ◽

Diffusion Method ◽

Dry Extract ◽

Brine Shrimp Lethality Assay ◽

Fungal Extracts ◽

Taxus Wallichiana

Background: Endophytic fungi are largely underexplored in the discovery of natural bioactive products though being rich sources of novel compounds with promising pharmaceutical potential. In this study, Taxus wallichiana, which has huge medicinal value, was investigated for its endophytic diversity and capability to produce bioactive secondary metabolites by analyzing antioxidant, antimicrobial and cytotoxic properties. Methods: The endophytes were identified by ITS-PCR using genomic DNA samples. The secondary metabolites were extracted by solvent extraction method using ethyl acetate. The antioxidant activity was analyzed by Thin Layer Chromatography, Total Phenol Content (TPC), Total Flavonoid Content (TFC) and DPPH assay, and the antimicrobial activity was analyzed by agar-well diffusion method. Brine shrimp lethality assay was used to analyze the cytotoxicity of the fungal extracts. Results: Out of 16 different Taxus trees sampled from different locations of Dhorpatan, 13 distinctive endophytic fungi were isolated and grouped into 9 different genera: Bjerkandera, Trichoderma, Preussia, Botrytis, Arthrinium, Alternaria, Cladosporium, Sporormiella and Daldinia. The ethyl acetate extracts isolated from three endophytic fungi: Alternaria alternata, Cladosporium cladosporioides and Alternaria brassicae showed significant TPC values of 204±6.144, 312.3±2.147 and 152.7±4.958µg GAE/mg of dry extract, respectively, and TFC values of 177.9±2.911, 644.1±4.202 and 96.38±3.851µg RE/mg of dry extract, respectively. Furthermore, these three extracts showed a dose dependent radical scavenging activity with IC50 concentration of 22.85, 22.15 and 23.001 µg/ml, respectively. The extracts of C. cladosporioides and A. brassicae also showed promising antimicrobial activity against Escherichia coli, Staphylococcus aureus and Bacillus subtilis with a minimum inhibitory concentration of 250μg/ml for all bacteria. Both the samples showed cytotoxic property against shrimp nauplii with LC50 of 104.2 and 125.9µg/ml, respectively. Conclusions: The crude fungal extracts obtained from endophytes: A. alternata, C. cladosporioides and A. brassicae upon purification and further identification of the bioactive compounds can be a fascinating source for novel pharmaceutical agents.

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Chemical Composition and Antimicrobial Activity of the Essential oils of 14 known Ficus species – A Concise Review

Biointerface Research in Applied Chemistry ◽

10.33263/briac126.80038034 ◽

2021 ◽

Vol 12 (6) ◽

pp. 8003-8034

Keyword(s):

Antimicrobial Activity ◽

Chemical Composition ◽

Essential Oil ◽

Essential Oils ◽

Bioactive Compounds ◽

Volatile Oils ◽

Good Source ◽

Concise Review ◽

Living Organisms

Compounds useful for drugs, cosmetics, and food have been obtained directly or indirectly from living organisms over the years. However, there has been a renewed interest in getting useful compounds from living organisms, especially plants. Essential oils, interchangeably called volatile oils, are bioactive compounds found in minute quantities in some plants. Essential or volatile oils have been known for years to find usefulness in foods, drugs (antimicrobial, antifungal), and cosmetics. This review attempts to summarize information on the essential oil from Ficus species concerning their morphology, pharmacology, bioactivity, and application. This was achieved by gathering information on essential oils from different Ficus species. Essential oils from Ficus species are a good source of bioactive compounds for use in drug, food, and cosmetic industries. It is worthy to note that Nigerian Figs were characterized by the high presence of phytol and 6,10,14-trimethyl-2-pentadecanone, and these compounds are, therefore, seen as markers. Furthermore, this review presents numerous insights on how to best harness the different potentials of the essential oils and possibilities to be examined.

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