scholarly journals Preliminary investigation on anthelmintic activity and phytochemical screening of leaf crude extracts of Tithonia diversifolia and Tephrosia vogelii

2014 ◽  
Vol 8 (25) ◽  
pp. 2449-2457 ◽  
Author(s):  
Justin KABERA ◽  
Rdampta TUYISENGE ◽  
Viateur UGIRINSHUTI ◽  
Anglique NYIRABAGENI ◽  
Straton MUNYABUHORO
2021 ◽  
Vol 11 (2) ◽  
pp. 119-126
Author(s):  
Ibrahim Hashim ◽  
Leonidah Kerubo Omosa ◽  
Vaderament-Alexe Nchiozem-Ngnitedem ◽  
John Mmari Onyari ◽  
Shital Mahindra Maru ◽  
...  

Author(s):  
Hamza Mohamed Ahmed ◽  
Ashraf Mahmoud Ramadhani ◽  
Ibrahim Yaagoub Erwa ◽  
Omer Adam Omer Ishag ◽  
Mohamed Bosharh Saeed

cinnamon dating from 1000 AD when it was firstly recorded in English due to its important as aroma and as herbs. The aim of this study was to investigate phytochemicals constitutes, chemical composition and antimicrobial activity of the essential oil of commercial samples of Cinnamon verum bark. The essential oil was extracted by hydrodistillation, while the crude extracts were prepared by three different solvents methanol (70%), acetone and aqueous. Phytochemical screening of crude extracts was performed using standard methods. The essential oil was subjected to GC-MS analysis and tested against Staphylococcus aureus, Salmonella typhimurium, Pseudomonas aeruginosa, Eschericchia coli and Candida albicans. The obtained results indicated the presence of alkaloids, flavonoids, coumarin, tannins, terpenoids, saponin, glycoside, anthrocyanin and phenolic compounds in the methanolic, aqoueous and acetone extracts of C. verum bark; while the major components of the extracted essential oil of C. verum bark were cinnamaldehyde (85.50%), stigmasterol (3.69%), Cadinene (1.37%), (E)-cinnamaldehyde (1.35%), alpha-amorphene (1.33%), hydrocinnamaldehyde (1.28%), alpha-cubebene (1.25) and ergosterol (1.09%) respectively. The antimicrobial activity result indicated the high activity of the extracted essential oil against all tested microorganisms at high concentration; except in S. typhimurium and C. albicans at concentrations of 25% and 12.5% no activity was noticed. Based in our obtained results the essential oil of C. verum bark had high potential as antimicrobial agent, therefore, recommended for more advanced studies to be conducted on this abundant plant as natural source of antibiotics.


2021 ◽  
Vol 14 (2) ◽  
pp. 640-644
Author(s):  
Kunal Bhattacharya ◽  
Atanu Bhattacharjee ◽  
Nongmaithem Randhoni Chanu ◽  
Biplab Kumar Dey ◽  
Chanam Melody Devi

2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Aliyi Hassen Ahmed ◽  
Mebrat Ejo ◽  
Teka Feyera ◽  
Dereje Regassa ◽  
Bahar Mummed ◽  
...  

Gastrointestinal nematodes (GINs) are the major limiting factor for the successfulness of livestock production throughout the world. Emergence of resistance strains as well as scarcity and high cost of the currently available drugs has led to the evaluation of other alternative helminth control options, mainly from plants. The current study is aimed at investigating the in vitro anthelmintic efficacy of crude methanolic extracts of two traditionally important medicinal plants, Artemisia herba-alba and Punica granatum, against Haemonchus contortus using adult motility assay (AMA) and egg hatch inhibition assay (EHIA). Four graded concentrations of the extracts were tested for both the AMA (10, 5, 2.5, and 1.25 mg/mg) and EHIA (0.1, 0.25, 0.5, and 1 mg/mL) in replicates. Albendazole and phosphate-buffered saline (AMA) or distilled water (EHIA) were used as the positive and negative controls, respectively. The crude extracts of A. herba-alba and P. granatum exhibited a potential anthelmintic activity at all dose levels in a concentration- and time-dependent fashion. The highest concentration (10 mg/mL) of all the extracts caused a significantly (p<0.05) superior nematocidal activity compared to the negative control. Moreover, significant and concentration-dependent egg hatching inhibition effect was observed from both plant extracts. Maximal (98.67%) egg hatching inhibition effect was exhibited by the flower extract of A. herba-alba at 1 mg/mL concentration. The relative egg hatch inhibition efficacy indicated that both plants caused a significantly (p<0.05) greater egg hatch inhibition within 48 hr of exposure. The current study validated the traditional use of both plants as a natural anthelmintic against H. contortus justifying a need to undertake detail pharmacological and toxicological investigation on both plants.


2015 ◽  
Vol 5 ◽  
pp. S166-S168 ◽  
Author(s):  
Narhari Das ◽  
Durajan Goshwami ◽  
Md. Sharif Hasan ◽  
Sheikh Zahir Raihan ◽  
Nirmal Kumar Subedi

Author(s):  
Gavalapu Venkateswara Rao ◽  
Abhinav kanagarla ◽  
Allamraju Satyakeertana ◽  
Vinukonda Alekhya ◽  
Dammu Saipriya ◽  
...  

2020 ◽  
Vol 26 (2) ◽  
pp. 165-170
Author(s):  
A.E. Ajiboye ◽  
R.A. Olawoyin

Carica papaya commonly known as paw paw belongs to the family of Curcubitaceae and commonly grown in tropical regions. It possesses  antimicrobial, antihelmintic and antioxidant properties. The study assessed the antibacterial potency of Carica papaya against Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus. Acetone and aqueous extracts of the leaves of Carica papaya were obtained using standard methods. The antibacterial activity of the extracts was done using agar well diffusion methods. The Minimum inhibitory and Minimum bactericidal concentrations were done using standard procedures. The antibacterial activities of the crude extracts of Carica papaya against the test organisms revealed that acetone extract showed maximum zone of inhibition on Staphylococcus aureus with a diameter of 17.90±0.10mm at 500 mg/ml and the lowest inhibitory effect on Klebsiella pneumoniae with a zone of 6.50±0.50mm at 100 mg/ml, the aqueous extract showed maximum zone of  inhibition on Staphylococcus aureus with a diameter of 15.50±0.50mm at 500 mg/ml and the lowest zone of inhibition was on Staphylococcus aureus with a diameter of 6.50±0.50mm at 100 g/ml. The Minimum Inhibitory Concentration of acetone and aqueous extract was 40 mg/ml and 50mg/ml against Klebsiella pneumoniae respectively. The Minimum Bactericidal Concentration of the extracts ranges from 40-60mg/ml. The qualitative  phytochemical screening result revealed the presence of tannins, saponnin, alkaloids and steroid. The quantitative phytochemicals revealed 0.70%  of flavonoids, 0.48% of alkaloids, 1.02% of tannin, 0.11% of steroids and 1.08% of glycoside. The result obtained revealed that crude extracts of Carica papaya leaves has antibacterial activities against the test organisms. Keywords: Carica papaya, Phytochemical screening, Pathogens, Antibacterial  activity


2021 ◽  
pp. 41-50
Author(s):  
Usha M ◽  
Reginald Appavoo M ◽  
Mohanraj V ◽  
Immanuel G

A preliminary investigation is provided to encouraging results for comprehensive studies on different aspects of the plant root - Ixora johnsonii  Hook.f. Root of this plant was studied to fix the parameters for pharmacognostical standards. The present study are highlights the pharmacognostical evaluation of root which includes macroscopic and microscopic features. Further, preliminary phytochemical analyses, organoleptic character, fluorescence behavior of different extracts and histochemical localization of phytochemicals. As there is no pharmacognostical work on record of this ethno botanically much valued drug, the present work was taken up with a view to lay down standards, which could be useful to detect the authenticity of this pretty plant.


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