scholarly journals TMPRSS6 rs855791 Polymorphism Influences the Susceptibility to Iron Deficiency Anemia in Women at Reproductive Age

2014 ◽  
Vol 11 (6) ◽  
pp. 614-619 ◽  
Author(s):  
Sung-Nan Pei ◽  
Ming-Chun Ma ◽  
Huey-Ling You ◽  
Hung-Chun Fu ◽  
Ching-Yuan Kuo ◽  
...  
Author(s):  
OJS Admin

Depression is a public health disorder, ranking third after respiratory and cardiac diseases. There were many evidences that iron deficiency anemia (IDA) is one of the foremost causes regarding nutritional pointof view for depression. We reviewed these evidences that IDAlinking to depression. We identified seventeen studies in four databases including randomized-controlled trials (RCTs) and observational studies assessing the impact of IDAand iron supplementation on the risk of depression. We extracted data on the basis of sample size, geographical region, measures of depression, hemoglobin, iron levels and intake of iron supplementation and critically appraised the results from the studies. Eleven out of sixty one studies were experimental, which indicated that dietary supplementation particularly iron supplementation had an association (r − 0.19 to −0.43 and ORs 1.70–4.64) with severity of depression. Evidences showed that women of reproductive age were more vulnerable to iron deficiency anemia than other population. Low ferritin and low hemoglobin level were associated with severity of depression. Iron is an essential nutrient for all living creatures, as a cofactor of various enzymes and plays significant role in environmental stimulant for the articulation of numerous virulence factors. Many clinical problems are caused by iron deficiency. Therefore, this review intended to highlight the important role of iron supplementation in reducing the severity of depression.


2003 ◽  
Vol 24 (3) ◽  
pp. 268-274 ◽  
Author(s):  
Mark Anthony Beinner ◽  
Joel Alves Lamounier

Iron-deficiency-anemia affects 30% of the world population. Women of reproductive age and children are the most affected. Iron supplementation in the form of tablets and syrups has not been successful in developing countries, and iron deficiency is still the most important deficiency related to malnutrition. Iron-deficiency anemia affects physical and cognitive development at an early age in children, often resulting in irreversible outcomes. Studies from the last two decades have shown that the prevalence of iron-deficiency anemia can be reduced given adequate investments and political will directed at iron fortification of foods and liquids. A successful low-cost iron-fortification program incorporates implementation and strategic use of communication for program inception where education is in the forefront. A review of the available reports from experience in Brazil with iron fortification of foods and liquids is presented.


2019 ◽  
pp. 22-28
Author(s):  
V. M. Nedoborenko ◽  
I. P. Kaidashev

Iron deficiency anemia (IDA) is one of the causes of chronic fatigue with a decrease in the quality of life, impaired cognitive function and poor labor productivity. Obesity as a condition of chronic low-intensity inflammation is one of the factors that increases the risk of anemia and impairs the quality of life in the general population. We drew attention to the high global prevalence of anemia among pregnant women of reproductive age in the world and the prevalence of high body mass index among women compared to men in most countries. The objective of the work was to determine the impact of obesity on clinical features and quality of life of women with ІDA. We analyzed the main markers of ІDA and hematologic indices in women with obesity (n = 30) compared with the control group (n = 10), where there were women with ІDA but without obesity. It was found that there was no statistical difference between these parameters, but nevertheless, the serum ferritin level in obese women was (4.70 ± 2.68) ng/ml compared to (3.50 ± 2.93) ng/ml and had a significant positive correlation with body mass index. The analysis of the questionnaires revealed that obesity is still a significant factor in women with ІDA and obesity, which determines the decrease in quality of life mainly in the physical aspect in the absence of significant influence on the psychosocial components of health.


2018 ◽  
Vol 08 (11) ◽  
pp. 993-1005 ◽  
Author(s):  
Parag Biniwale ◽  
Bhaskar Pal ◽  
Tripura Sundari ◽  
Gorakh Mandrupkar ◽  
Nikhil Datar ◽  
...  

2014 ◽  
Vol 29 ◽  
pp. 24-32
Author(s):  
Rakesh Kumar

Anemia constitutes a public health problem, in both developed and developing countries with major burden on economic and social develop ment. Present study was designed to examine the prevalence of anemia among girl students of Abhilashi College, Distt Mandi Himachal Pradesh. Hemoglobin (Hb) level of 87 girls students was determined. Prevalence of anemia was detected to have been quite high at 55%. Self-awareness of the condition among those anemic was dismally low at 10%. Health education constitutes an important approach to increase awareness about anemia in terms of exposures, risk factors, essential nutrition ingredients an d the importance of iron supplementations. Thus, the present study has tried to focus on those issues which are responsible for determining the level of anemia among wo men aged 20 to 40 years and has also tried to provide scientific exp lanations of iron deficiency anemia.


Anemia ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Julia G. Shaw ◽  
Jennifer F. Friedman

Iron deficiency anemia is thought to affect the health of more than one billion people worldwide, with the greatest burden of disease experienced in lesser developed countries, particularly women of reproductive age and children. This greater disease burden is due to both nutritional and infectious etiologies. Individuals in lesser developed countries have diets that are much lower in iron, less access to multivitamins for young children and pregnant women, and increased rates of fertility which increase demands for iron through the life course. Infectious diseases, particularly parasitic diseases, also lead to both extracorporeal iron loss and anemia of inflammation, which decreases bioavailability of iron to host tissues. This paper will address the unique etiologies and consequences of both iron deficiency anemia and the alterations in iron absorption and distribution seen in the context of anemia of inflammation. Implications for diagnosis and treatment in this unique context will also be discussed.


2016 ◽  
Vol 23 (09) ◽  
pp. 1092-1098
Author(s):  
Ghazala Masood Farrukh ◽  
Zainab Hasan ◽  
Samar Ikram ◽  
Batha Tariq

Globally about two billion people suffer from anemia of various types amongstwhich Iron Deficiency Anemia (IDA) is the most prevalent type. According to National NutritionSurvey of Pakistan 2011 (NNS), 50.4 % of non-pregnant females suffer from IDA, despite thefact that a variety of low cost, indigenous food sources of iron are available, affordable andaccessible in Pakistan. IDA is a risk factor for complications of pregnancy and low birth weightbaby and is also an independent cause of morbidity and mortality in all ages. Therefore thisstudy was conducted to determine the dietary patterns of iron intake in females of reproductiveage group who had IDA without any other known cause. Study Design: A cross sectionalstudy. Setting: Three tertiary care centers of Ziauddin Hospital located at Clifton, Kemari andNorth Nazimabad. Methods: Reproductive age females suffering from IDA according to theirCBC profile within three months prior to the study were selected through purposive sampling.Females taking iron supplements or with any known cause of iron deficiency were excluded.Total of 141 eligible and consenting IDA patients filled a 7 Day dietary recall questionnaireto determine the iron intake of indigenously available iron rich foods and blood sample wascollected for hematological profiles and iron studies. Results: Mean iron intake was 6.41 ±4.39 mg/day. Median heme and non heme iron intake was 8.0 mg and 28.0 mg per week,respectively. 52.4% of our study population had moderate IDA, 38.2% had pica for one or moresubstance and almost all suffered from one or more symptoms of iron deficiency. Majority ofthe population was consuming non-heme sources of iron. Conclusion: The iron consumptionfrom indigenous dietary sources is very low and contributes significantly to development of IDA.Increasing awareness regarding signs and symptoms of IDA and common dietary sources ofiron will contribute to screening, early diagnosis and correction of the iron deficit thus promotinghealth and preventing complications.


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