scholarly journals Evaluation of antipsychotic effect of methanolic extract of Ocimum sanctum leaves on laboratory animals

2016 ◽  
pp. 171-177 ◽  
Author(s):  
Kailash Sharma ◽  
Milind Parle ◽  
Monu Yadav
Keyword(s):  
Methanolic Extract ◽  
Laboratory Animals ◽  
Ocimum Sanctum ◽  
Antipsychotic Effect

scholarly journals Antimicrobial Activity and HPLC Fingerprinting of CrudeOcimumExtracts

2011 ◽  
Vol 8 (3) ◽  
pp. 1430-1437 ◽  
Author(s):  
S. S. Deo ◽  
F. Inam ◽  
R. P. Mahashabde
Keyword(s):  
Antimicrobial Activity ◽  
Methanolic Extract ◽  
Ocimum Sanctum ◽  
Moderate Activity ◽  
Aqueous Extracts ◽  
Gram Positive ◽  
Strong Activity ◽  
Gram Negative ◽  
E Coli ◽  
Strong Antimicrobial Activity

The antimicrobial activity of crude methanolic and aqueous extracts ofOcimum sanctumandOcimum kilimandsacharicumagainst gram positive, gram negative and antifungal activity was evaluated to find the zone of inhibition and to set a HPLC profile or fingerprint of these extracts. The crude methanolic extract ofOcimum sanctumshowed strong antimicrobial activity againstS.aureusandC. albicansand moderate activity againstE. coliandB. subtilis. The crude methanolic extract ofOcimum kilimandsacharicumshowed strong antimicrobial activity againstS. aureus, E. coliandC. albicansat higher concentration, same as that shown by the standard forC. albicans. It showed moderate activity againstB. subtilis. The crude aqueous extracts of Ocimum sanctum showed strong antimicrobial activity againstS.aureusand moderate against others. Whereas the crude aqueous extracts ofOcimum kilimandsacharicumshowed moderate activity against the gram positive and gram negative organisms and strong activity againstC. albicansat higher concentration, same as that shown by the standard forC. albicans.

scholarly journals Evaluation of antibacterial efficacy of Ocimum sanctum L. against certain bacterial species and phytochemical analysis

2021 ◽  
Vol 22 (3) ◽  
pp. 341-345
Author(s):  
Aparajita Gupta ◽  
Mandeep Kaur
Keyword(s):  
Antibacterial Activity ◽  
Bacillus Cereus ◽  
Aqueous Extract ◽  
Methanolic Extract ◽  
Bacterial Species ◽  
Diffusion Method ◽  
Ocimum Sanctum ◽  
Phytochemical Analysis ◽  
Antibacterial Efficacy ◽  
Minimum Value

In the present study antibacterial efficacy of  aqueous and methanol extract obtained from leaves and stem of Ocimum sanctum L. was evaluated against certain test bacterial species viz. Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, and Bacillus cereus. It is a traditional medicinal herb, commonly used for the treatment of various human health disorders.  The antibacterial activity was determined by using agar well diffusion method. Among the solvent extracts tested, aqueous extract of leaves exhibited higher antibacterial activity as compared to methanolic extract of leaves. Maximum antibacterial activity was recorded 17.6 mm against Bacillus cereus and minimum value was recorded 14 mm against S. aureus. Maximum antibacterial efficacy of O. sanctum leaves was found 7.3mm against P. aeruginosa and minimum value was 5mm against B. cereus in methanolic extract. Similar trend has been observed in extract of stem of O. sanctum in aqueous and methanolic solvent. The antibacterial efficacy has been found nil in methanolic extract. However in aqueous extract moderate activity has been recorded i.e. 9.3 mm against E.coli and minimum 7.3 mm against K. pneumoniae. The trend of phytochemicals revealed non significant variation. Phytochemical analysis of leaves and stem extracts of O. sanctum revealed the presence of various phytoconstituents i.e. alkaloids, flavonoids, saponins, tanins, glycosides.

Effect of aqueous/methanolic extract of Ocimum sanctum (OciBest) on the Male and Female reproductive performance of wistar rats

2018 ◽  
Vol 14 (55) ◽  
pp. 256
Author(s):  
R Kaul-Ghanekar ◽  
P Raina ◽  
B Bharathi ◽  
A Senthilkumar ◽  
S Sagar ◽  
...  
Keyword(s):  
Reproductive Performance ◽  
Wistar Rats ◽  
Methanolic Extract ◽  
Ocimum Sanctum ◽  
Male And Female

scholarly journals Study of In-vitro Antioxidant and Antibacterial activity of leaf extract of Azadirachta indica, and Ocimum sanctum in different organic solvents and Cow urine

2020 ◽  
Vol 10 (1-s) ◽  
pp. 90-95
Author(s):  
Nisha Adhikari ◽  
Anita Rana ◽  
Sangita Oli ◽  
Srijana Neupane ◽  
Ravin Bhandari ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Methanolic Extract ◽  
Therapeutic Potential ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Ocimum Sanctum ◽  
Scavenging Activity ◽  
Neem Extract ◽  
E Coli ◽  
Cow Urine

Background: Neem (Azadirachta indica), Tulsi (Ocimum sanctum) and Cow urine (Bos indicus) has been widely used as a therapeutic potential or additive agent in different ethnomedicinal practices as well as modern science also proved its therapeutic potential to treat various diseases and balance the body conditions. Aims: Alone study on Neem, Tulsi and Cow urine (CU) has been widely performed but this study aims to evaluate the individual as well as synergistic antioxidant and antibacterial activity of Neem, and Tulsi’s leaves extract in different organic solvents and Cow urine. Materials and Methods: Antioxidant activity was carried out by using 2,2-Diphenyl1-picrylhydrazyl (DPPH) radical scavenging activity and the antibacterial activity was tested by the agar disc diffusion method against gram-positive (Staphylococcus aureus)  and gram-negative (Escherichia coli, Proteus vulgaris and Klebsiella species) bacteria. Results: The antioxidant and antibacterial activity is concentration-dependent. The neem extract in chloroform shows the highest ZOI against S. aureus (14±2). Similarly, the neem extract in cow urine (8±0.86) and tulsi extract in methanol (8±1.04) shows the highest ZOI against E. coli. Against K. species cow urine is most effective (9±0.29) followed by neem extract in chloroform and cow urine (8±0.77). In P. vulgaris almost all sample shows ZOI around 7 mm. In synergistic antibacterial study tulsi and neem extract in cow urine shows the highest ZOI against E. coli (12±1.75) and P. vulgaris (10±1.44). The tulsi and neem extract in hexane is not effective against S. aureus and E. coli but effective in P. vulgaris and K. species (ZOI 7 mm). Tulsi and neem extract in chloroform, methanol, and cow urine show similar ZOI (9 mm). In DPPH free radical scavenging activity the methanolic extract of tulsi shows the highest inhibition of free radicle (96.35±0.001), followed by methanolic extract of neem (84.85±0.042). The fresh cow urine inhibits (25.19±0.037) followed by neem extract in chloroform (24.53±0.003), neem extract in cow urine (21.8±0.012), tulsi extract in chloroform (20.86±0.047), tulsi extract in hexane (19.5±0.031), tulsi extract in cow urine (18.33±0.023) and the least inhibition by neem extract in hexane (6.74±0.042).

scholarly journals Phytochemical screening and antioxidant activity of methanolic extract of Ocimum sanctum Linn. Leaves

2019 ◽  
Vol 8 (2) ◽  
pp. 022-033 ◽  
Author(s):  
SS Priyadarshini Harichandan ◽  
Ajay Kumar Sahu ◽  
Sakshi Gautam ◽  
Rahul Nemani
Keyword(s):  
Antioxidant Activity ◽  
Methanolic Extract ◽  
Ocimum Sanctum ◽  
Phytochemical Screening
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