scholarly journals Hubungan Jenis Persalinan dan Prematuritas dengan Hiperbilirubinemia di RS Persahabatan

2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Elsa Roselina ◽  
Saroha Pinem ◽  
Rochimah Rochimah
Keyword(s):  
Logistic Regression ◽  
Statistical Analysis ◽  
Research Design ◽  
Medical Records ◽  
Odds Ratio ◽  
Case Control ◽  
P Value ◽  
Maternal Factor ◽  
Multivariable Logistic Regression

ABSTRACT. Hyperbilirubinemia refers to an excessive level of accumulated bilirubin in the blood and ischaracterized by jaundice, or icterus, a yellowish discoloration of the skin and other organs. There are two riskfactors that related to hyperbilirubinemia. Those factors are maternal factor and neonates‟ factor. The aim ofthis research knew which variables which catagorized as maternal factor and neonates‟ factor that related tohyperbilirubinemia in Persahabatan hospital. This research used medical records from 216 neonates andhis/her mother from October 2008 until October 2009 as samples. Research design was case control, with used5% level of significant and 80% power. The statistical analysis was multivariable logistic regression. Factorsthat related to hyperbilirubinemia in Persahabatan hospital were type of labor (p value 0.000) andprematurity (p value 0.022). Type of labor is a dominant variable that related to hyperbilirubinemia andneonates from un-spontaneous labor has probability to be hyperbilirubinemia 50.193 times than neonates fromspontaneous labor after controlled by prematurity (odds ratio 50.193).Keywords: hyperbilirubinemia, type of labor, prematurity

scholarly journals The Effect of Patient Characteristics with Intravenous Catheter To Phlebitis

2018 ◽  
Vol 6 (1) ◽  
pp. 1
Author(s):  
Nella Mega Fadhilah Haritya Akbar ◽  
Muhammad Atoillah Isfandiari
Keyword(s):  
Nutritional Status ◽  
Odds Ratio ◽  
Clinical Status ◽  
Patient Characteristics ◽  
Case Control ◽  
Dominant Factor ◽  
P Value ◽  
Intravenous Therapy ◽  
Intravenous Catheter ◽  
Independent Variables

ABSTRAK Terapi intravena merupakan salah satu prosedur invasif yang bertujuan untuk mensuplai cairan, obat, vitamin, komponen darah, dan monitoring status hemodinamik. Pasien yang mendapatkan terapi intravena dalam jangka panjang berisiko tinggi terinfeksi, plebitis dan ekstravasasi vena. Penelitian ini bertujuan untuk menganalisis pengaruh karakteristik pasien terpasang kateter intravena terhadap kejadian plebitis. Desain penelitan ini adalah case control dengan besar sampel 45 pasien pada kelompok kasus dan kontrol. Sampel kasus pada penelitian ini adalah pasien yang terdiagnosa plebitis sedangkan sampel kontrol adalah pasien yang tidak terdiagnosa plebitis di RSU Haji Surabaya pada bulan Januari sampai dengan April 2017. Variabel independen adalah umur, jenis kelamin, status gizi, hipertensi dan DM, sedangkan variabel dependen adalah kejadian plebitis. Pengelolahan data menggunakan analisis regresi logistik berganda. Hasil penelitian ini menunjukan bahwa dari 5 faktor terkait dengan karakteristik pasien hanya 3 faktor yang berpengaruh terhadap kejadian plebitis adalah  jenis kelamin dengan p value = 0,043 dan odds ratio = 3,45, umur dengan p value = 0,016 dan odds ratio 4,10 dan  DM dengan p value = 0,000 dan odds ratio = 9,78. Sedangkan 2 faktor yang tidak berpengaruh terhadap kejadian plebitis adalah status gizi dengan p value = 0,74 dan odds ratio = 0,79 dan hipertensi dengan p value = 0,178 dan odds ratio = 2,35. Berdasarkan hasil analisis data, dapat disimpulkan bahwa faktor dominan dan berpengaruh terhadap kejadian plebitis adalah status DM. Hasil penelitian ini diharapkan dapat menjadi acuan bagi RSU Haji Surabaya, terutama dalam prosedur pemasangan dan perawatan terapi intravena yang perlu mempertimbangkan kondisi pasienKata Kunci : Karakteristik, intravaskular, pengaruh, plebitis, terapi intravena.ABSTRACTIntravenous therapy is one of the most common invasive procedures used for injecting  fluids, drugs, blood products, nutritional and monitoring of hemodynamic status. The insertion and daily use of these devices isassociated with risk plebitis and complications that can have impact on the clinical status and outcome of the patient.. The aims of this research was  to analyze the effect of patient characteristics on intravenous catheter to the occurrence of plebitis. This study used case control with sample size 45  for each group. Case sample was patients who diagnosed with plebitis while control samples was diagnosed patients with no plebitis at RSU Haji Surabaya in January until April 2017. Independent variables were age, sex, nutritional status, hypertension and DM, whereas the depenendent variable was plebitis occurrence. Those variables was analyze with  logistic regression. The results of this study showed that the 5 factors related to the characteristics of patients only 3 factors that affect the incidence of plebitis include the gender with p value = 0.043 and odds ratio = 3.45, age with p value = 0.016 and odds ratio 4.10 and DM with p value = 0.000 and odds ratio = 9.78. While the 2 factors that have no effect on the occurrence of plebitis is the nutritional status with p value = 0.74 and odds ratio = 0.79 and hypertension with p value = 0.178 and odds ratio = 2.35. Based on the results of data analysis, it can be concluded that the most dominant factor and the effect on the occurrence of plebitis is DM status. The results of this study are expected to be a reference for RSU Haji Surabaya, especially in the installation procedure and treatment of intravenous therapy that needs to consider the condition of the patientKeywords: Characteristics, influences, intravascular, intravenous therapy, plebitis.

scholarly journals Male Gender Increases the Risk of Liver Fibrosis in Patients with Thalassemia Major Independent of Iron Overload

Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 3630-3630
Author(s):  
Murtadha K. Al-Khabori ◽  
Said Al Busaifi ◽  
Al Ghaliya Al Omairi ◽  
Moez Hassan ◽  
Humoud Al Dhuhli ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Liver Fibrosis ◽  
Iron Overload ◽  
Iron Concentration ◽  
Thalassemia Major ◽  
Male Gender ◽  
Ultrasound Elastography ◽  
P Value ◽  
Positive Serology ◽  
Multivariable Logistic Regression

Abstract Introduction and Objectives: Iron overload in patients with Thalassemia Major (TM) leads to various complications including liver fibrosis. The independent impact of gender on this risk has been previously investigated but not yet confirmed. We, therefore, planned to assess the independent impact of gender in patients with TM on the risk of liver fibrosis. Methods: We included 96 patients with TM followed and transfused in one academic tertiary hospital. Patients underwent assessment of liver fibrosis using ultrasound elastography (FibroScan device) with a cut off value of 7.8 kPa. The mean ferritin in the 5 years prior to elastography assessment was used to represent iron overload. Association was tested using Chi-squared and the independent impact of gender was confirmed in the multivariable logistic regression with a model that included mean ferritin and gender. Results: The median age of the 96 included patients was 26 years (Interquartile range [IQR]: 22-30). Males constituted 45% of patients and 33% of patients were splenectomised. The median alanine transaminase, aspartate transaminase, albumin and total bilirubin were 30 U/L (IQR: 18-64), 30 U/L (IQR: 18-46), 46 g/L (IQR: 44-48) and 21 µmol/L (IQR: 14-32) respectively. The median ferritin and liver iron concentration assessed by MRI T2* were 1293 µg/L (IQR: 753-2715) and 6.7 mg/gdw (IQR: 3.5-16.1) respectively. Thirty seven percent of patients had positive serology for HCV while 1% of patients had positive serology for HBV. The proportion of patients with fibrosis as assessed by elastography was 59%. The proportion of male patients with fibrosis was 70% compared to 51% in female patients with a trend towards statistical significance (odds ratio [OR] of 2.2 with a p value of 0.094). In the multivariable logistic regression model, both gender (OR of 3.0, P value of 0.0188) and ferritin (OR of 1.0004, p value of 0.0036) were statistically significant independent predictors of liver fibrosis. Conclusion: Male gender increases the risk of liver fibrosis independent from iron overload. Our study confirms the previously suspected but unproven association. Follow up and therapy may be tailored to include gender as a decision factor. Larger studies are needed to further confirm these results. Disclosures No relevant conflicts of interest to declare.

scholarly journals Relationship Between Unbound Bilirubin Levels and Acute Bilirubin Encephalopathy in Exchange Transfusion Neonates

2021 ◽  
Author(s):  
Yiyi Ding ◽  
Shuo Wang ◽  
Rui Guo ◽  
Aizhen Zhang ◽  
Yufang Zhu
Keyword(s):  
Logistic Regression ◽  
Blood Glucose ◽  
Odds Ratio ◽  
Exchange Transfusion ◽  
Binary Logistic Regression ◽  
P Value ◽  
Bilirubin Encephalopathy ◽  
Unbound Bilirubin ◽  
Independent Variable ◽  
The Relationship

Abstract BACKGROUND: Evidence regarding the relationship between unbound bilirubin levels and acute bilirubin encephalopathy was limited. Therefore, this study set out to investigate whether the unbound bilirubin level was independently related to acute bilirubin encephalopathy in children who underwent exchange transfusion after adjusting for other covariates. METHODS: A total of 46 neonates who underwent exchange transfusion were involved in The First People's Hospital Of Changde City in China from 2016-1-1 to 2018-12-31. The target independent variable and the dependent variable were unbound bilirubin levels measured at baseline and acute bilirubin encephalopathy respectively. Covariates involved in this study included sex, age, birth weight, blood glucose, red blood cell, hemolysis, receive phototherapy before exchange transfusion. RESULTS: The average gestational age of 46 selected participants was 38.6 ± 1.3 weeks old, the average age was 146.5 ± 86.9 hours old, 52.17% of them were male. Result of fully-adjusted binary logistic regression showed unbound bilirubin levels were positively associated with risk of acute bilirubin encephalopathy after adjusting confounders (Odds ratio = 1.41, 95% confidence intervals 1.05-1.91, P value <0.05). CONCLUSION: Unbound bilirubin levels are associated with neonatal acute bilirubin encephalopathy. The mechanism of unbound bilirubin levels leading to neonatal acute bilirubin encephalopathy needs to be further explored.

Female Authorship in Radiology: Trends in the Past Decade in CARJ

2020 ◽  
pp. 084653712094664
Author(s):  
Nicole Li ◽  
Mostafa Alabousi ◽  
Michael N. Patlas
Keyword(s):  
Logistic Regression ◽  
Statistical Analysis ◽  
P Value ◽  
Inclusion Criteria ◽  
Odds Ratios ◽  
The Past ◽  
Single Author ◽  
Canadian Association ◽  
Female Authorship ◽  
Over Time

Purpose: To identify trends in female authorship in the Canadian Association of Radiologists Journal (CARJ) from 2010 to 2019. Methods: We retrieved papers published in the CARJ over a 10-year period, and retrospectively reviewed 602 articles. All articles except editorials and advertisements were included. We categorized the names of the first and last position authors as female or male and excluded articles that had at least one author of which gender was not known. We compared the trends in the first and last position authors of the articles from 2010 to 2019. For statistical analysis, logistic regression was performed with reported odds ratios (ORs), and a P value of <.05 was defined as statistically significant. Results: Five hundred thirteen articles met inclusion criteria. Among them, 23 articles with a single author were classified as having only a first author. 39.8% (204/513) of first authors were female and 26.9% (132/490) of last authors were female. There has been an overall temporal increase in the odds of both the first and last author being female in CARJ publications (OR: 1.11, P = .034). Similarly, the odds a CARJ publication’s first author being female increased over time (OR: 1.07, P = .033). Female last author did not predict female first author (OR: 1.48, P = .056). There was no association identified between female last author and year of publication (OR: 1.04, P = .225). Conclusion: There has been an overall increase in engagement of female authorship in CARJ.

scholarly journals Multiple sclerosis relapse risk in the postoperative period: Effects of invasive surgery and anesthesia

2019 ◽  
Vol 26 (11) ◽  
pp. 1437-1440
Author(s):  
Lindsey B De Lott ◽  
Samantha Zerafa ◽  
Kerby Shedden ◽  
Galit Levi Dunietz ◽  
Michelle Earley ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Logistic Regression ◽  
Medical Records ◽  
Odds Ratio ◽  
Conditional Logistic Regression ◽  
Unadjusted Odds Ratio ◽  
Relapse Risk ◽  
Multiple Sclerosis Relapse ◽  
Period Effects ◽  
Tertiary Center

Background: Postoperative multiple sclerosis (MS) relapses are a concern among patients and providers. Objective: To determine whether MS relapse risk is higher postoperatively. Methods: Data were extracted from medical records of MS patients undergoing surgery at a tertiary center (2000–2016). Conditional logistic regression estimated within-patient unadjusted and age-adjusted odds of postoperative versus preoperative relapse. Results: Among 281 patients and 609 surgeries, 12 postoperative relapses were identified. The odds of postoperative versus preoperative relapse in unadjusted (odds ratio (OR) = 0.56, 95% confidence interval (CI) = 0.18–1.79; p = 0.33) or age-adjusted models (OR = 0.66, 95% CI = 0.20–2.16; p = 0.49) were not increased. Conclusions: Surgery/anesthesia exposure did not increase postoperative relapse risk. These findings require confirmation in larger studies.

scholarly journals Prognosis of Pregnancy in Epileptics in Benin: A Case–Control Study

2020 ◽  
Vol 11 (03) ◽  
pp. 395-402
Author(s):  
Thierry Adoukonou ◽  
Mendinatou Agbétou ◽  
Rachidi Imorou Sidi ◽  
Colombe Gnansounou ◽  
Donald Accrombessi ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Birth Weight ◽  
Odds Ratio ◽  
Case Control Study ◽  
Case Control ◽  
Pregnancy And Childbirth ◽  
Epilepsy Treatment ◽  
Epileptic Woman ◽  
Epileptic Women ◽  
Control Study

Abstract Objective The main purpose of this article is to define prognosis of pregnancies in epileptic women in Benin. Methods This was a case–control study that included 54 epileptic women who had at least one pregnancy matched to 162 controls on age, pregnancy term, and monitoring center. Information about epilepsy, treatment, pregnancy, and childbirth were collected. A logistic regression with odds ratio (OR) calculation was used to study the association. Results During pregnancy 22.22% of epileptic women experienced an increase in seizure frequency. Epileptics had more frequent miscarriages (OR: 1.84 [1.01–3.51]), more incidents during pregnancy (OR: 4.03 [1.04–15.60]), and were more often hospitalized (OR: 3.35 [1.46–7.69]) than women without epilepsy. They, more often, had premature children before 37 weeks of amenorrhea (OR: 2.10 [1.12–3.91]) and gave birth to low-birth-weight children (OR = 2.17 [1.00–4.76]). Conclusion Occurrence of a pregnancy in an epileptic woman in Benin is at risk and requires multidisciplinary monitoring by both neurologist and obstetrician to reduce complications.

A Risk-Prediction Model For Identifying Venous Thromboembolism In Hospitalized Pediatric Patients: A Single Institution Retrospective Case-Control Analysis

Blood ◽  
2013 ◽  
Vol 122 (21) ◽  
pp. 2957-2957
Author(s):  
Ruchika Goel ◽  
Jessy Dhillon ◽  
Craig Malli ◽  
Kishen Sahota ◽  
Prabhjot Seehra ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Venous Thromboembolism ◽  
Risk Prediction ◽  
Research Funding ◽  
Pediatric Patients ◽  
Univariate Analysis ◽  
Case Control ◽  
Control Analysis ◽  
Multivariable Logistic Regression

Abstract Introduction Venous thromboembolism (VTE) is increasing in children, especially in the tertiary care setting. Hospital-associated VTE (HA-VTE) is a potentially preventable cause of major morbidity and mortality. However, the incidence of HA-VTE VTE is low in children Risk stratification tools may aid in identification of hospitalized high risk pediatric patients who may benefit from VTE prophylaxis. Methods We conducted a case-control study of pediatric patients with HA-VTE (21 years or younger at the time of diagnosis) admitted to the Johns Hopkins Hospital from 2008-2010. Cases were identified using ICD-9 codes for DVT and PE and verified by reviewing hospital records and radiologic imaging reports. HA-VTE was defined as: 1) VTE was diagnosed ≥48 hours after hospital admission without signs/symptoms of VTE on admission, or 2) VTE was diagnosed within 90 days of hospital discharge. Two contemporaneous controls matched for age, sex and admission unit were selected for each case. Records of cases and controls were reviewed for presence of a priori identified putative VTE risk factors at admission. Univariate and conditional multivariable logistic regression analyses with backward elimination were used to develop risk-prediction models. Based on results of univariate analysis, we sought to evaluate two multivariable models, one without length of stay (LOS) with relevance to assessment at admission, and one in which LOS was included with relevance to re-assessment after several days of hospitalization. All variables selected for the multivariable model were tested for interaction with a significance threshold level of p<0.2. Except for this, all hypothesis testing was two tailed and a p value of <0.05 was considered significant. Receiver operator curves (ROC) were constructed using risk factors on multivariate analysis. Results Table 1 lists the results putative risk factors by univariate analysis with a) significantly higher odds of VTE and b) higher odds of VTE but not statistically significant. In multivariable logistic regression analysis, central venous catheter (CVC), VTE predisposition and immobility or LOS >5 days were independently associated with HA-VTE. The combination of CVC and VTE predisposition with either immobility or LOS was predictive of HA-VTE (area under the curve for ROC of 76.6% and 80.6%, Table 2). Conclusion We found independently associated risk factors with that may potentially be used in a predictive model of HA-VTE in children. Further prospective validation studies of these and other risk factors may serve as the basis of future risk-stratified randomized control trials of primary prevention of pediatric HA-VTE. Disclosures: Streiff: Bristol Myers Squibb: Research Funding; Sanofi: Consultancy, Honoraria; Eisai, Daiichi-Sankyo, Boehringer-Ingelheim, Janssen HealthCare: Consultancy. Strouse:NIH: Research Funding; Doris Duke Charitable Foundation: Research Funding; Masimo Corporation: Membership on an entity's Board of Directors or advisory committees, Research Funding. Takemoto:Novonordisk: Research Funding.

Incidence of complications associated with tibial tuberosity advancement in Boxer dogs

2016 ◽  
Vol 29 (01) ◽  
pp. 39-45 ◽  
Author(s):  
Rui Sul ◽  
Tim Parkin ◽  
Ignacio Calvo ◽  
Brigite de Lima Dantas
Keyword(s):  
Revision Surgery ◽  
Medical Records ◽  
Odds Ratio ◽  
Surgical Repair ◽  
Cruciate Ligament ◽  
Tibial Tuberosity ◽  
P Value ◽  
Cranial Cruciate Ligament ◽  
Cranial Cruciate Ligament Disease ◽  
Boxer Dogs

SummaryObjective: To retrospectively review and describe the incidence of complications associated with tibial tuberosity advancement (TTA) surgical procedures in a group of Boxer dogs (n = 36 stifles) and compare the data with a non-Boxer control population (n = 271 stifles).Methods: Retrospective analysis of medical records to identify all dogs that underwent TTA surgery due to cranial cruciate ligament disease. These records were categorized into two groups: Boxer dogs and non-Boxer dogs (controls – all other breeds).Results: Of the 307 stifles included, 69 complications were reported in 58 joints. The complication rate differed significantly for Boxer dogs (16/36 stifles) and non-Boxer dogs (42/271 stifles), corresponding to an odds ratio of 5.8 (confidence interval: 1.96–17.02; p-value <0.001). Boxer dogs were more likely to undergo revision surgery and to develop multiple complications. The incidence of tibial tuberosity fractures requiring surgical repair (2/36 versus 1/271) and incisional infections requiring antibiotic treatment (three in each group) was significantly higher in the Boxer group.Clinical significance: Boxer dogs had more major and multiple complications after TTA surgery than the control non-Boxer group; these complications included higher rates of revision surgery, tibial tuberosity fractures requiring stabilization, and infection related complications. The pertinence and value of breed-specific recommendations for cranial cruciate ligament disease appears to be a subject worthy of further investigation.

scholarly journals Clinical and Laboratory Predictors of Mortality in Patients With SARS-CoV-2 Infection in A Tertiary Care Center of Central Kerala, India - A Case control Study

2021 ◽  
Vol 6 (4) ◽  
pp. 111-120
Author(s):  
Priyanka Rajmohan ◽  
◽  
Anil Kumar Chellappan pillai Chellappan pillai Rajamma ◽  
Mimtha Ayiravelil Mohanan ◽  
Ponnu Jose ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Serum Creatinine ◽  
Case Control Study ◽  
Univariate Analysis ◽  
Tertiary Care ◽  
Case Control ◽  
Hospital Death ◽  
Predictors Of Mortality ◽  
Multivariable Logistic Regression ◽  
Control Study

Background: Since various studies indicate differences in the case fatality rate of SARS-CoV-2 in different settings, it is vital to elucidate the clinical and laboratory parameters. This would be helpful in identifying individuals who are susceptible to adverse outcomes, thereby targeting essential health interventions to resource poor settings. This study aimed to determine the clinical and laboratory predictors of mortality due to COVID-19. Materials & Methods: In this case control study, we included 162 adult inpatients who died due to COVID-19 from May 2020 to February 2021, as cases (n=81) and those discharged as controls (n=81). Demographic, clinical, treatment, and laboratory data was extracted from medical records and electronic database and compared between survivors and non-survivors. Univariate analysis and multivariable logistic regression methods were used to identify the risk factors associated with in-hospital death. Results: Comorbidities were present among 82 (50.6%) participants. Hypertension was the most common comorbidity 99(61.1%) followed by diabetes mellitus 92 (56.8%) and coronary artery disease 55(34%). Multivariable logistic regression model showed that cardiovascular disease (OR=5.80, 95%CI: 1.09–47.55, P=0.011), decreased oxygen saturation (OR=33.68, 95%CI: 2.81–403.80, P=0.006), elevated CRP (OR=1.16, 95%CI: 1.01–1.32, P=0.026), and serum creatinine (OR=3.26, 95%CI: 1.02–11.55, P=0.047) were the significant predictors of mortality. Conclusion: This study found that comorbidities such as CAD, elevated serum creatinine, elevated inflammatory markers, and decreased O2 saturation were independent predictors of mortality among COVID-19 patients.

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