Association of serum fetuin-B with insulin resistance and pre-diabetes in young Chinese women: evidence from a cross-sectional study and effect of liraglutide

Background and Aims Fetuin-B has been reported to be involved in glucose and lipid metabolism and associated with the occurrence of diabetes. The main purpose of this study is to explore the changes of circulating fetuin-B in young women with pre-diabetes and to analyze the relationship between fetuin-B and the occurrence and development of IR. Methods A total of 304 women were enrolled in this study and subjected to both OGTT and EHC. A subgroup of 26 overweight/obese womenwas treated with Lira for 24 weeks. serum fetuin-B concentrations were measured by ELISA. Results In IGT and IR-NG groups, serum fetuin-B levels were higher than those in the NGT group. The serum fetuin-B levels in the IGT group were higher than those in the IR-NG group. serum fetuin-B was positively correlated with BMI, WHR, 2h-BG, FIns, HbA1c, and HOMA2-IR, but negatively correlated with the M-value in all study populations. Multiple stepwise regression analysis showed that the M-value was independently and inversely associated with serum fetuin-B. Logistic regression analysis showed that serum fetuin-B was independently associated with IGT and significantly increased the risk of IGT. During the OGTT, serum fetuin-B increased significantly in the NGT group, but there were no significant changes in other groups. During the EHC, serum fetuin-B increased in the IGT group, but there was no change in other groups. After Lira intervention, serum fetuin-B decreased significantly in IGT women. Conclusions serum fetuin-B levels are elevated in young women with IR or IGT and may be associated with IR.

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C1q/TNF-Related Protein5 (CTRP5) as a Biomarker to Predict Metabolic Syndrome and Each of Its Components

International Journal of Endocrinology ◽

10.1155/2018/7201473 ◽

2018 ◽

Vol 2018 ◽

pp. 1-8 ◽

Cited By ~ 2

Author(s):

Feiyu Jiang ◽

Min Yang ◽

Xili Zhao ◽

Rui Liu ◽

Gangyi Yang ◽

...

Keyword(s):

Insulin Resistance ◽

Metabolic Syndrome ◽

Binary Logistic Regression ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Multiple Stepwise Regression Analysis ◽

Glucose And Lipid Metabolism ◽

Study Population ◽

The Relationship

Objective. C1q/TNF-related protein5 (CTRP5) is a member of the C1q/tumor necrosis factor α- (TNF-α-) related protein family and has been reported to be associated with the regulation of glucose and lipid metabolism. However, the clinical association between CTRP5 and metabolic syndrome (MetS) has not been reported. The aim of the current study is to investigate the association between CTRP5 and MetS by a cross-sectional study. Methods. We performed a cross-sectional study in a Chinese population including 89 controls and 88 MetS individuals. Serum CTRP5 concentrations were determined by ELISA. The relationship between circulating CTRP5 and MetS and insulin resistance (IR) was assessed by Spearman’s correlation and multiple stepwise regression analysis. Results. Circulating CTRP5 concentrations were markedly decreased in MetS individuals relative to normal adults. Overweight/obese individuals (BMI ≥ 25 kg/m2) showed a lower serum CTRP5 level than lean subjects (BMI < 25 kg/m2) in the study population (124.1 (99.12–147.37) vs. 103.9 (79.15–124.25) μg/L; P<0.01). Circulating CTRP5 was found to be correlated negatively with BMI, FAT%, FBG, WHR, SBP, HbA1c, TG, 2-hour blood glucose after glucose overload (2-hOGTT), FIns, and HOMA-IR and positively with HDL-C (P<0.05 or P<0.01). Binary logistic regression revealed that serum CTRP5 levels were associated with MetS. In addition, serum CTRP5 levels gradually decreased with the increase in MetS components. Conclusions. Circulating CTRP5 is relative to the elevated risk of MetS in humans and may be in part through the effect of insulin resistance. This trial is registered with ChiCTR-OCS-13003185.

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Knowledge and Attitudes Regarding HPV and Vaccination Among Chinese Women Aged 20 to 35 Years in Fujian Province

Cancer Control ◽

10.1177/1073274818775356 ◽

2018 ◽

Vol 25 (1) ◽

pp. 107327481877535 ◽

Cited By ~ 13

Author(s):

Lihua Chen ◽

Yiyi Song ◽

Guanyu Ruan ◽

Qiaoyu Zhang ◽

Fen Lin ◽

...

Keyword(s):

Young Women ◽

Hpv Vaccine ◽

Chinese Women ◽

Hpv Vaccination ◽

Hpv Infection ◽

Cross Sectional Study ◽

Detailed Knowledge ◽

Fujian Province ◽

Cross Sectional ◽

Knowledge And Attitudes

The use of the human papillomavirus (HPV) vaccine was recently approved in Mainland China. This study determined the knowledge and attitudes of young women aged 20 to 35 years in Fujian Province, China, with regard to HPV and vaccination and explored the potential factors influencing their attitudes toward HPV vaccination. This was a cross-sectional study that collected data regarding the knowledge on and attitudes toward HPV and vaccination using questionnaires. Furthermore, the prevalence of HPV was determined from the sampled participants. A total of 1001 young women were included in the survey. This study demonstrated that the HPV prevalence rate was 15.7% (157/1001). Among all patients, 44.9% (n = 449) had heard of HPV; however, detailed knowledge about HPV was lacking. The majority (83.7%) expressed a willingness to be vaccinated. Specifically, knowledge of the dangers of HPV infection was significantly associated with the willingness to be vaccinated. In this study, women cited some concerns and expressed high expectations for the HPV vaccine, but the costs of vaccination reduced their willingness to be vaccinated. This study found that most patients did not have a detailed knowledge of HPV. Thus, there is a need for continued HPV promotion and education efforts, especially on the dangers of HPV infection, among young women aged 20 to 35 years in Fujian Province, China. Furthermore, it is important to subsidize the costs of vaccination for promoting vaccination campaigns in China.

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Relationship Between Smoking, Narcissism, and Impulsiveness Among Young Women

10.21203/rs.3.rs-1108170/v1 ◽

2021 ◽

Author(s):

Semion Kertzman ◽

Alex Kagan ◽

Michael Vainder ◽

Rina Lapidus ◽

Abraham Weizman

Keyword(s):

Personality Traits ◽

Young Women ◽

Empirical Support ◽

Cross Sectional Study ◽

Personality Characteristics ◽

Sectional Study ◽

Cross Sectional ◽

Narcissistic Personality ◽

Narcissistic Personality Inventory ◽

The Relationship

Abstract Although the connection between smoking and individual differences has been recently recognized, the relationship between narcissistic personality traits and cigarette smoking has received less attention. The notion that personality traits can be associated with addictive behavior is influential in clinical practice. However, questions remain about specific interactions between smoking and personality characteristics that need empirical support to substantiate this hypothesis. This study thus identifies narcissistic and impulsive personality traits as precursors of smoking in a sample of tattooed individuals. In a cross-sectional study (N = 120), personality traits were assessed in young women (aged 18-35 years) using the Narcissistic Personality Inventory (NPI) and the Barratt Impulsivity Scale (BIS-11). The current study, using the regression analysis, has clearly demonstrated that young women who smoke have different personality characteristics as compared with women who do not smoke.

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Relationship between Serum Levels of OPG and TGF-βwith Decreasing Rate of BMD in Native Chinese Women

International Journal of Endocrinology ◽

10.1155/2013/727164 ◽

2013 ◽

Vol 2013 ◽

pp. 1-8

Author(s):

Xi-Yu Wu ◽

Yi-Qun Peng ◽

Hong Zhang ◽

Hui Xie ◽

Zhi-Feng Sheng ◽

...

Keyword(s):

Lumbar Spine ◽

Linear Regression ◽

Chinese Women ◽

Serum Levels ◽

Cross Sectional Study ◽

Distal Forearm ◽

Sectional Study ◽

Cross Sectional ◽

The Relationship ◽

Positive Determinant

The objective of this study was to investigate the relationship between serum levels of OPG, TGF-β1, and TGF-β2 and BMD decrease rate (BDR) in native Chinese women. This cross-sectional study was performed on 465 healthy native Chinese women aged 35–80 years. Serum levels of OPG, TGF-β1, and TGF-β2 were determined. BDR was measured by DXA at the posteroanterior spine, hip, and distal forearm. At all skeletal sites tested, there was a negative correlation between BDR and serum levels of both OPG (r=−0.122to –0.230, allP= 0.007–0.000) and TGF-β2 (r=−0.100to –0.173, allP= 0.029–0.000) and a positive correlation between BDR and serum TGF-β1 (r=0.245−0.365, allP=0.000). After adjustment for age and BMI, there were no statistically significant correlations between serum levels of OPG or TGF-β2 and BDR. However, statistically significant correlations between serum TGF-β1 and BDR at the lumbar spine and ultradistal forearm remained. Multiple linear regression stepwise analysis showed that serum OPG could explain 1.4–3.7% of BDR variation. Serum TGF-β1 was a positive determinant of BDR and could explain 5.3–13.3% of BDR variation.

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Evaluation of Relationship between Mesiodistal Width of Permanent Canines and Premolars with Permanent Lower First Molars and Incisors for Space Analysis

Journal of Isfahan Dental School ◽

10.18502/ijds.v17i2.6878 ◽

2021 ◽

Author(s):

Shabnam Yazdani ◽

Nasim Esnaashari ◽

Mehdi Rafie ◽

Negah Bazghaleh

Keyword(s):

Regression Analysis ◽

Cross Sectional Study ◽

P Value ◽

Sectional Study ◽

Prediction Formula ◽

Cross Sectional ◽

Present Cross Sectional Study ◽

The Relationship ◽

Dental Cast ◽

Digital Caliper

Introduction: One of the simplest methods to predict mesiodistal width of permanent canines and premolars is using Tanaka and Johnston’s prediction formula; however, dental size varies according to race. The study aimed to examine the relationship between incisors mesiodistal width and mandibular first molar’s with mesiodistal width of maxillary and mandibular canines and premolars and to determine the reliability of Tanaka and Johnston prediction formula. Materials & Methods: In the present cross-sectional study, 200 pairs of a dental cast of 12-25 years old were selected and the greatest mesiodistal width of canines and premolars crown in each jaw and incisors and mandibular first molars were measured with a digital caliper with 0.01 resolution. Data were analyzed using regression analysis, t-test (p value < 0.05). Results: There was a significant statistical difference between actual width and Tanaka and Johnston prediction formula in the group under study (p value < 0.001). Moreover, a new linear equation for the prediction of mesiodistal width of maxillary and mandibular canines and premolars based on mesiodistal width of lower incisors and mandibular first molars was developed using regression analysis. Conclusion: In statistical terms, Tanaka and Johnston’s prediction formula is not applicable for the population under study because maxillary estimated measures were a little high and mandibular estimated measures were a little low.

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Association between Obesity and Omega-3 Status in Healthy Young Women

Nutrients ◽

10.3390/nu12051480 ◽

2020 ◽

Vol 12 (5) ◽

pp. 1480

Author(s):

Isabel E. Young ◽

Helen M. Parker ◽

Rebecca L. Cook ◽

Nicholas J. O’Dwyer ◽

Manohar L. Garg ◽

...

Keyword(s):

Metabolic Disease ◽

Young Women ◽

Cross Sectional Study ◽

Normal Weight ◽

Omega 3 ◽

Alpha Linolenic Acid ◽

Cross Sectional ◽

Healthy Development ◽

Increased Risk ◽

The Relationship

Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are essential for healthy development and protect against metabolic disease. However, individuals with obesity may be pre-disposed to experiencing lower n-3 PUFA status than normal-weight individuals. This cross-sectional study examined the relationship between the omega-3 index (O3I), body mass index (BMI) and dietary intake in healthy young women (n = 300; age = 18–35 y), a group not previously focused on. Intake was adjusted for energy using the residuals method, and associations were explored using independent t-tests and Pearson’s correlations. Participants with obesity were found to have significantly lower O3I than normal-weight participants (p < 0.0001); however, no significant differences were observed in mean n-3 PUFA intakes. Even so, energy-adjusted intakes of n-3 PUFAs, with the exception of alpha-linolenic acid, were significantly correlated with O3I. This study demonstrates that O3I is influenced by both BMI and diet in young women; however the relationship between these two variables may be complex. Current intakes of n-3 PUFA observed in young women may not be effective in achieving target O3I levels in those with obesity, and further research is needed to find effective ways of improving n-3 PUFA status in a group already at increased risk of metabolic disease.

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The association of acne and menstrual symptoms among young women (18–25 years) in Egypt: a population-based cross-sectional study

International Journal of Adolescent Medicine and Health ◽

10.1515/ijamh-2019-0220 ◽

2020 ◽

Vol 0 (0) ◽

Author(s):

Ahmed Arafa ◽

Alshimaa Mostafa ◽

Yasser Khamis

Keyword(s):

Young Women ◽

Population Based ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Multi Stage ◽

Menstrual Symptoms ◽

History Of ◽

The Relationship ◽

Age Of Menarche

AbstractBackgroundAcne and menstrual symptoms are highly prevalent among young women. Since both acne and menstrual symptoms have similar hormonal pathogenesis, it is highly suggested that the two conditions are associated. Herein, we conducted this study to assess the relationship between acne and menstrual symptoms among young women.Subjects and methodsIn this population-based cross-sectional study, a multi-stage random sampling approach was used to include 3065 young women (18–25 years) from Egypt. Women were interviewed for their socio-demographic characteristics, gynecological history, premenstrual and menstrual symptoms, and history of acne and perimenstrual acne flare during the past 6 months.ResultsThe mean age of women was 21.5 ± 2.2 and their age of menarche was 13.1 ± 1.5 years. During the previous 6 months, 44.8% of participants had acne. After adjusting for socio-demographic and gynecological characteristics, acne was associated with most menstrual symptoms with odds ratios (ORs) and 95% confidence intervals (CIs) as follows: [premenstrual symptoms: 1.23 (1.05–1.44) for irritation or nervousness, 1.45 (1.24–1.68) for fatigue, 1.37 (1.15–1.62) for breast tenderness, 1.48 (1.21–1.80) for abdominal bloating, and 1.36 (1.11–1.66) for nausea or vomiting], [menstrual symptoms: 1.63 (1.19–2.23) for dysmenorrhea and 1.24 (1.06–1.45) for dysmenorrhea requiring drugs], and [symptoms severity: 1.44 (1.24–1.68) for missing events and 1.38 (1.16–1.64) for medical consultation]. Of acne patients, 56.7% reported perimenstrual acne flare: 58.5% before menses, 35% during menses, and 6.5% after menses.ConclusionThis study supports the concept that acne is associated with menstrual symptoms. Physicians should consider screening for menstrual symptoms among young women with acne.

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STUDI KORELASI ANTARA STATUS GIZI DENGAN SIKLUS MENSTRUASI PADA REMAJA PUTRI DI SMA NEGERI 7 PEKANBARU

Jurnal Keperawatan Abdurrab ◽

10.36341/jka.v2i2.620 ◽

2019 ◽

Vol 2 (2) ◽

pp. 19-22

Author(s):

Tri Siwi Kusuma Ningrum ◽

Yeni Yarnita ◽

Novi Lestari

Keyword(s):

Menstrual Cycle ◽

Nutritional Status ◽

Young Women ◽

Cross Sectional Study ◽

P Value ◽

Sampling Techniques ◽

Sectional Study ◽

Cross Sectional ◽

Probability Sampling ◽

The Relationship

ABSTRACT Menstrual cycle is a pattern that describes the distance between the first day of menstruation with the first day of menstruation in the next period. The pattern of the menstrual cycle can change which can be influenced by many factors, one of which is a person's nutritional status. The purpose of this study was to determine the relationship between nutritional status and the menstrual cycle in young women in Pekanbaru 7 High School. This type of research uses a cross sectional study with probability sampling sampling techniques with totaling 220 respondents. Data collection used a questionnaire about the menstrual cycle and measurement of nutritional status using body mass index. The results showed that there was no significant relationship between nutritional status and the menstrual cycle with the p-value (p = 0.755). Keywords: nutritional status, menstrual cycle ABSTRAK Siklus menstruasi merupakan pola yang menggambarkan jarak antara hari pertama menstruasi dengan hari pertama menstruasi pada periode berikutnya. Pola siklus menstruasi bisa berubah ubah yang dapat dipengaruhi oleh banyak faktor salah satunya status gizi seseorang. Tujuan dari penelitian ini untuk mengetahui adanya hubungan status gizi dengan siklus menstruasi pada remaja putri di SMA Negeri 7 Pekanbaru. Jenis penelitian menggunakan cross sectional study dengan tehnik pengambilan sampel probability sampling yang berjumlah 220 responden. Pengumpulan data menggunakan kuesioner tentang siklus menstruasi dan pengukuran status gizi menggunakan indeks massa tubuh. Hasil Penelitian menunjukkan bahwa tidak terdapat hubungan yang bermakna antara status gizi dengan siklus menstruasi dengan nilai p-value (p=0,755).

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Nursing work intention, stress, and professionalism in response to the COVID-19 outbreak in Iran: A cross-sectional study

Work ◽

10.3233/wor-205099 ◽

2021 ◽

pp. 1-11

Author(s):

Hamed Zandian ◽

Minoo Alipouri-sakha ◽

Elhameh Nasiri ◽

Telma Zahirian Moghadam

Keyword(s):

Regression Analysis ◽

Multiple Regression Analysis ◽

Significant Relationship ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Training Groups ◽

Nursing Services ◽

The Relationship ◽

Previous Training

BACKGROUND: Professionalism, stress and demographic factors are the three key influences in nurses’ intention to provide care. OBJECTIVES: This study examined the levels of work intention, stress and professionalism of nurses and determine the relationship between nursing work intention and factors in response to COVID-19. METHODS: This cross-sectional study was conducted on 362 nurses from COVID-19-devoted hospitals in Iran. A self-administered electronic-based questionnaire was developed and used to determine levels of stress, professionalism, and nursing intention. Multiple regression analysis was carried out to analyze the correlation between nursing intention with respect to stress and professionalism. RESULTS: The overall stress, professionalism, and nursing intention scores were 48.56, 21.46, and 17.83 respectively. There were significant differences in nursing intention scores between gender, marital status, and having training groups (p < 0.05). The regression analysis revealed that nursing intention had a significant relationship with older age (p < 0.001, S.E = 1.11,B = 17.02), higher income level (p < 0.001,S.E = 1.81,B = 6.98), having previous training (p = 0.008,S.E = 1.22,B = 3.27), higher stress level (p < 0.001,S.E = 2.37,B = –21.39), and high professionalism level (p < 0.001,S.E = 1.16,B = 11.99). CONCLUSION: Having an adequate staff requirement plan, planning appropriate training for nurses, and proactive psychological support are crucial to prevent burnout and continue to provide nursing services.

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Association of Serum Myonectin Concentrations With the Presence of Atrial Fibrillation

10.21203/rs.3.rs-322401/v1 ◽

2021 ◽

Author(s):

Chun Wang ◽

Ye Luo ◽

Liangxian Qiu ◽

Xiaosu Li ◽

Qianwen Huang ◽

...

Keyword(s):

Atrial Fibrillation ◽

Blood Pressure ◽

Regression Analysis ◽

Left Atrial ◽

Stepwise Regression ◽

Healthy Controls ◽

Left Atrial Diameter ◽

Multiple Stepwise Regression Analysis ◽

Group Serum

Abstract Objective: Myonectin, a recently found myokine, has a role of inhibiting inflammation. The aim of this research is to see if myonectin levels are linked to the occurrence of atrial fibrillation (AF).Methods: We examined serum myonectin in a population of 194 patients with AF who were then classified into three subgroups: paroxysmal AF, persistent AF, and permanent AF. Atrial remolding was assessed using left atrial diameter (LAD). Results: Serum myonectin was significantly lower in AF group compared with healthy controls. Logistic regression analysis demonstrated that serum myonectin concentrations were correlated with a decreased risk of AF. Patients with permanent AF displayed decreased serum myonectin than in persistent and paroxysmal AF groups. Serum myonectin was lower in persistent AF group than in paroxysmal AF group. Serum myonectin concentrations in AF patients were negatively associated with body mass index (BMI), systolic blood pressure, diastolic blood pressure, and LAD. BMI and LAD stayed to be correlated with serum myonectin according to multiple stepwise regression analysis. Conclusion: Our study demonstrated a correlation between serum myonectin and AF.

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