Conventional Herbal Plants in Modern Periods : The Therapeutic Potential Syzigium cumuni and Hyperglycemia

Author(s):  
Zeliha Selamoglu ◽  
Senay Ozgen

Herbal plants are using for folk medicine since immemorial times. Hippocrates who is the father of medicine, refer to 400 medicinal plants and advised ‘‘let food be your medicine and let medicine be your food’’. Most of plants are using today for medicine. It is still acceptable today that prevention is more important than treatment. Saffron was utilized in folk remedy against scarlet fever, smallpox, colds, asthma, eye and heart diseases, tumours, and cancer.


Molecules ◽  
2021 ◽  
Vol 26 (22) ◽  
pp. 6881
Author(s):  
Muhammad Issa Khan ◽  
Maria Maqsood ◽  
Raakia Anam Saeed ◽  
Amna Alam ◽  
Amna Sahar ◽  
...  

Herbal plants have been utilized to treat and cure various health-related problems since ancient times. The use of Ayurvedic medicine is very significant because of its least reported side effects and host of advantages. Withania coagulans (Family; Solanaceae), a valuable medicinal plant, has been used to cure abnormal cell growth, wasting disorders, neural as well as physical problems, diabetes mellitus, insomnia, acute and chronic hepatic ailments. This review provides critical insight regarding the phytochemistry, biological activities, and pharmacognostic properties of W. coagulans. It has been known to possess diuretic, anti-inflammatory, anti-bacterial, anti-fungal, cardio-protective, hepato-protective, hypoglycemic, anti-oxidative, and anti-mutagenic properties owing to the existence of withanolides, an active compound present in it. Apart from withanolides, W. coagulans also contains many phytochemicals such as flavonoids, tannins, and β-sterols. Several studies indicate that various parts of W. coagulans and their active constituents have numerous pharmacological and therapeutic properties and thus can be considered as a new drug therapy against multiple diseases.


2020 ◽  
Vol 16 ◽  
Author(s):  
Mohammed Asadullah Jahangir ◽  
Mohamad Taleuzzaman ◽  
Sarwar Beg ◽  
Surajpal Verma ◽  
Sadaf Jamal Gilani ◽  
...  

: Eugenol is a bioactive compound frequently available in many herbal plants. The different sources reported for eugenol are clove, cinnamon, holy basil, and pepper. There are several therapeutic activities reported for eugenol as antioxidant, antimicrobial, anesthetic, antiinflammatory, anti-carcinogenic, neuroprotective agent, anti-diabetic and anti-cancer agent. However, due to limited aqueous solubility they have poor bioavailability. Their therapeutic potential has been enhanced with the eugenol nano-formulations developed as liposome, nanoparticles, microemulsions and micelles. This article extensively reviews the chemical properties, pharmacological properties, andeugenol nano-formulations with their biological activity.


Author(s):  
Rashita Makkar ◽  
Tapan Behl ◽  
Arun Kumar ◽  
Priya Nijhawan ◽  
Sandeep Arora

Objectives: Rheumatoid arthritis is a chronic inflammatory autoimmune disease characterized by failure of spontaneous resolution of inflammation with lifetime perseverance, becoming one of the major causes of disability in millions of people. It is mainly characterized with progressive erosion of cartilage in response to formation of pannus leading to chronic polyarthritis and joint distortion. Early diagnosis and advances in molecular biology undoubtedly revolutionized therapeutic interventions in the past decade for better disease management. Despite favorable prospects, many patients still fail to respond to the current therapies urging a burning need to develop newer and safer medications. Key findings: Herbal plants have been utilized since ancient era and provided base for massive bioactive compounds with flaunting therapeutic potential, many being advanced to drugs which are consumed worldwide for treating countless ailments. Scientific studies showed involvement of several cellular mechanisms like oxidative stress suppression, downregulated synthesis of proinflammatory cytokines namely interleukins (IL-1, IL-6), TNF-α, NF-κB, demoted metalloproteinases induced cartilage destruction and augmentation of free radical scavenging and antioxidant activity in treatment of rheumatoid arthritis. A plethora of active phytoconstituents like flavonoids, saponins, terpenes, alkaloids, lactones etc have been isolated from herbal plants with proven curative actions. Summary: The present review enlists some of the herbal drugs that can be used to amend the effects of rheumatoid arthritis and impart symptomatic relief to patients.


Author(s):  
Supriya Roy ◽  
Himani Awasthi

Neurodegeneration refers to a condition of neuronal death occurring as a result of progressive disease of long termand is becoming a major health problem in the 21st century. Neurons degenerated are not replaced resulting in cognitive loss ,many neurodegenerative disorders, such as schizophrenia, depression, Alzheimer's Disease (AD) dementia, cerebrovascular impairment, seizure disorders, head injury, Parkinsonism. Neuroprotection refers to the strategies and possible mechanisms that are able to protect the central nervous system (CNS) against neuronal injury and neurodegenerative disorders. The past decade has witnessed an intense interest in herbal plants having long-term health promoting or medicinal qualities. Comprehensive research and discovery has demonstrated that natural products, medicinal herbs, plant extracts, and their metabolites, have great potential as neuroprotective agent. Although the precise mechanisms of action of herbal drugs have yet to be determined, some of them have been shown to exert anti-inflammatory and/or antioxidant effects. Thus the herbal plants can be a valuable source of drug against neurodegenerative disorders which will require high-throughput screening. This review will highlight the role of herbal plants and their phytoconstituents against neurodegenerative diseases and other related disorders, focusing on their mechanism of action and therapeutic potential. Keywords:


Author(s):  
Etetor Roland Eshiet ◽  
Ernest E. Smith

This chapter per the authors will introduce the reader to Complementary and Alternative Medicine (CAM) and shall discuss herbalism as a subset of CAM. Particular emphasis will be placed on herbal teas or rather infusions and decoctions used in disease therapy. This chapter will enumerate the different types of teas and shall use maps, graphs, and other tools to illustrate location, consumption, use and availability. Furthermore, the authors will highlight potential health benefits, recent studies (in vitro, in vivo) undertaken by research scientists to validate efficacy, and shall call for more research (clinical data management, clinical trials, etc.) and support for ongoing work in this area of expertise. The authors shall place a spotlight on the plant family, Asteraceae, and their herbal plants of interest, Artemisia annua and Brickellia cavanillesii. Extensive studies have been performed to determine the therapeutic potential of Brickellia cavanillesii plant at Ernest E. Smith laboratory, The Institute of Environmental and Human Health (TIEHH), Texas Tech University, Lubbock, USA.


2018 ◽  
pp. 287-320
Author(s):  
Etetor Roland Eshiet ◽  
Ernest E. Smith

This chapter per the authors will introduce the reader to Complementary and Alternative Medicine (CAM) and shall discuss herbalism as a subset of CAM. Particular emphasis will be placed on herbal teas or rather infusions and decoctions used in disease therapy. This chapter will enumerate the different types of teas and shall use maps, graphs, and other tools to illustrate location, consumption, use and availability. Furthermore, the authors will highlight potential health benefits, recent studies (in vitro, in vivo) undertaken by research scientists to validate efficacy, and shall call for more research (clinical data management, clinical trials, etc.) and support for ongoing work in this area of expertise. The authors shall place a spotlight on the plant family, Asteraceae, and their herbal plants of interest, Artemisia annua and Brickellia cavanillesii. Extensive studies have been performed to determine the therapeutic potential of Brickellia cavanillesii plant at Ernest E. Smith laboratory, The Institute of Environmental and Human Health (TIEHH), Texas Tech University, Lubbock, USA.


Author(s):  
Maruti Shelar ◽  
Vaibhav Gawade ◽  
Santosh Bhujbal

Nearly 70-80% of the world's population relies on non-conventional medicines, often derived from herbal plants, according to World Health Organization (WHO) figure. Medicinal plants are starting material for any herbal preparation such as herbal medicines, herbal teas, herbal oil etc. These preparations are being used worldwide due to their therapeutic potential and as they are considered to be safe as compared to allopathic medicines. Lead, cadmium, chromium, nickel, arsenic and mercury are the most common toxic metals that have become a matter of concern due to the reports of their contamination in various herbal preparations and herbal ingredients .Although the minimum acceptable limits have been laid out as safety concern. Heavy metal are evaluated by AAS, ICP-OES, ICP-MS, XRFS, HPLC, DPP, NAA, ASV and disposable sensor applications for achieving therapeutic efficacy and evolutions of heavy metal in herbals. 


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