scholarly journals Ethnobotany, Phytochemical, Pharmacological Potentials of Murraya koenigii, and Its Health Benefits – A Review

Author(s):  
Priyanka Goyal ◽  
Rohit Chhabra ◽  
Lavanya Vij

Murraya koenigii, also widely known as curry leaves and curry patta, is a noticeably significant plant recognized all around the world for its tremendous therapeutic, medicinal worth and characteristic aromatic properties. It is one of the major export commodities originated from east and southern part of India bringing good foreign revenue. This review article is designed to assess and compile all the currently available literature on ethnobotanical aspects and phytochemical, pharmacological potentials of M. koenigii. Morphologically, it is a semi deciduous small shrub or aromatic shrub having slender but strong woody stem with branches covered with grey bark. The whole plant of M. koenigii viz., as stem, leaf, fruits, root and seeds have been accounted to have anti-oxidant, anti-fungal, anti-candidal, anti-bacterial, anti-hypersensitive and various biological properties. It is also additionally used in hormonal therapy in traditional medicines as a dysenteric, blood purifier, diuretic, febrifuge, hair tonic, anti-inflammatory, analgesic, antipyretic and anti-diarrheal. M. koenigii oil is said to have massive impact in the pharmaceuticals and in aromatherapy enterprises as a powerful ingredient. Many researchers have worked on all parts of M. koenigii, from roots, stem, leaves up its bark. This review is an attempt to summarize all the diverse literature available so as to compile a reliable review article on M. koenigii providing detailed information on therapeutic potential, health benefits and pharmacological applications of the plant.

Author(s):  
Abiche Ekalu ◽  
James Dama Habila

Abstract Background The unique and vast pharmacological activities of flavonoids have made them of research interest. This led to the use of various techniques to isolate and characterize them, intending to determine their potential health benefits. Main text The medicinal values of plant-based flavonoids that this literature review tends to summarize the pharmacological activities of these secondary metabolites from 22 selected plant families. The pharmacological shreds of evidence reported in the literature have proven that flavonoids have shown anti-cancer, anti-microbial, anti-oxidant, anti-inflammatory, anti-fungal, anti-ulcer, and anti-edematogenic activities. Out of these, 30% showed to have anti-oxidant activity, key in protecting the body against free radicals. Besides, 18% of the references showed anti-microbial and anti-cancer activities. Further literature reports indicated that flavonoids from these families exhibited anti-inflammatory and anti-edematogenic (9%), anti-viral and anti-ulcer (5%), anti-fungal, anti-nociceptive, and anti-histamine (2%). Conclusion The pharmacological activities of flavonoids from the various sources reviewed in this study show that the secondary metabolites could provide a scaffold for the development of potent anti-cancer drugs in the future.


Author(s):  
Santosh Jain Passi

Functional foods containing physiologically-active components, have been reported to confer several health benefits. Longitudinal cohort studies indicate that certain foods and dietary patterns play an important role in primary prevention of numerous disease conditions and this has led to the identification of putative functional foods. Research is necessary to substantiate the potential health benefits of various functional foods for which the diet–health relationships have yet not been scientifically validated. The term ‘functional foods' may include health/functional health foods, foods fortified with minerals/vitamins, dietary supplements or even the traditional medicines (Zawistowski, 2014).


Marine Drugs ◽  
2019 ◽  
Vol 17 (6) ◽  
pp. 361 ◽  
Author(s):  
Bandana Manandhar ◽  
Pradeep Paudel ◽  
Su Hui Seong ◽  
Hyun Ah Jung ◽  
Jae Sue Choi

The marine biosphere is a treasure trove of natural bioactive secondary metabolites and the richest source of structurally diverse and unique compounds, such as phlorotannins and halo-compounds, with high therapeutic potential. Eckol is a precursor compound representing the dibenzo-1,4-dioxin class of phlorotannins abundant in the Ecklonia species, which are marine brown algae having a ubiquitous distribution. In search of compounds having biological activity from macro algae during the past three decades, this particular compound has attracted massive attention for its multiple therapeutic properties and health benefits. Although several varieties of marine algae, seaweed, and phlorotannins have already been well scrutinized, eckol deserves a place of its own because of the therapeutic properties it possesses. The relevant information about this particular compound has not yet been collected in one place; therefore, this review focuses on its biological applications, including its potential health benefits and possible applications to restrain diseases leading to good health. The facts compiled in this review could contribute to novel insights into the functions of eckol and potentially enable its use in different uninvestigated fields.


2018 ◽  
Vol 13 (9) ◽  
pp. 1934578X1801300 ◽  
Author(s):  
Mariangela Marrelli ◽  
Fabrizio Araniti ◽  
Maria Rosa Abenavoli ◽  
Giancarlo Statti ◽  
Filomena Conforti

The potential health benefits of the essential oils of six different populations of Origanum heracleoticum L. from Calabria (Italy) were assessed, together with the evaluation of the influence of the site of collection on their metabolic profile and biological activity. Different terpenoids were identified, being thymol, carvacrol and o-cymene among the most abundant ones. Hierarchical cluster analysis allowed the identification of two main groups, which were discriminated by the altitude of collection. The antioxidant activity was tested by means of two in vitro assays: DPPH and β-carotene bleaching test. Samples EO-4 and EO-3 were the most active in protecting linoleic acid from peroxidation, with IC50 values of 4.00 and 4.68 μg/mL after 30 minutes of incubation. The anti-inflammatory potential was assessed through the evaluation of the capacity to inhibit NO production in lipopolysaccharide (LPS)-induced murine macrophage RAW 264.7 cell line. All essential oils induced a dose-depending inhibitory effect. An excellent activity was demonstrated for sample EO-4, followed by sample EO-3 (IC50 values equal to 32.77 and 49.48 μg/mL, respectively). Observed biological properties were correlated to the phytochemical content of analyzed samples.


2020 ◽  
Vol 23 (26) ◽  
pp. 2916-2944
Author(s):  
Nader G. Khaligh ◽  
Hanna Abbo ◽  
Salam J.J. Titinchi ◽  
Mohd R. Johan

: This review article provides a brief assessment of the biological and pharmaceutical developments of fluorinated drugs. It also discusses possible impacts on the further development of new fluoro-containing pharmaceuticals. Structural aspects of new drug-candidates currently under development and their biological properties, therapeutic potential and syntheses are critically evaluated


Author(s):  
Ena Gupta ◽  
Pragya Mishra

: The possible beneficial properties of functional foods are due to their content in bioactive ingredients, with specific biological properties. A number of processed functional foods are available in the market – probiotic yogurt, calcium and ω-3 fatty acids enriched orange juice and milk. Simultaneously, new research studies confer potential health benefits of various conventional foods (salmon, berries, green tea, vegetables, fruits, nuts, cereals and breads etc) termed as “superfood” which is a marketing term and there is no established medical definition. Following suitable dietary patterns superfood reduces the risk of degerative diseases by promoting physical and emotional health. Scientific evidences suggests that superfood are dense source of antioxidants, minerals, vitamins and other nutrients. There is insufficient research on the exact explanation of term ‘superfood’and its health claims by different companies without any legislation. This buzz word making confusion among consumers, that how much and what quantity should make a food superfood, as no single food may be as nutritious to be stated as superfood. This article introduces further investigation on superfood which was categorized on the basis of their major constituents and potential health benefits. Further there is a need of more reviews, researches, clinical trials and human case studies to investigate or test superfood.


2021 ◽  
Vol 11 (6) ◽  
pp. 14225-14239

Garlic (Allium sativum) is amongst the oldest medicinal plant in centuries. It is an amazing plant that contains numerous bioactive components such as organosulfur compounds, allicin, s-allyl cysteine, S-allyl-mercapto cysteine, diallyl sulfide, diallyl disulfide, and diallyl trisulfide. This review discusses numerous valuable effects and therapeutic potential of garlic in treating several diseases such as cancer, obesity, diabetes, liver injury, hypertension, inflammation, viral infection, and arthritis. The enormous immunomodulatory, anti-oxidant, and anti-microbial characteristics of garlic have also been explained briefly. This review article also gives insight into the nanotechnology-based phytopharmaceuticals of garlic; has summarized pre-clinical models, clinical trials, and patents published about garlic's therapeutic applications and its phytoconstituents in the management of several disease conditions. This review article brings more attention to garlic, providing effective scientific proof for improved utilization of garlic in human health and disease control.


Author(s):  
Santosh Jain Passi

Functional foods containing physiologically-active components, have been reported to confer several health benefits. Longitudinal cohort studies indicate that certain foods and dietary patterns play an important role in primary prevention of numerous disease conditions and this has led to the identification of putative functional foods. Research is necessary to substantiate the potential health benefits of various functional foods for which the diet–health relationships have yet not been scientifically validated. The term ‘functional foods' may include health/functional health foods, foods fortified with minerals/vitamins, dietary supplements or even the traditional medicines (Zawistowski, 2014).


2021 ◽  
Vol 8 ◽  
Author(s):  
Shelini Surendran ◽  
Fatimah Qassadi ◽  
Geyan Surendran ◽  
Dash Lilley ◽  
Michael Heinrich

Myrcene (β-myrcene) is an abundant monoterpene which occurs as a major constituent in many plant species, including hops and cannabis. It is a popular flavouring and aroma agent (food additive) used in the manufacture of food and beverages. This review aims to report on the occurrence, biological and toxicological profile of β-myrcene. The main reported biological properties of β-myrcene—anxiolytic, antioxidant, anti-ageing, anti-inflammatory, analgesic properties—are discussed, with the mechanisms of activity. Here we also discuss recent data regarding the safety of β-myrcene. Overall, β-myrcene has shown promising health benefits in many animal studies. However, studies conducted in humans is lacking. In the future, there is potential for the formulation and production of non-alcoholic beers, functional foods and drinks, and cannabis extracts (low in THC) rich in β-myrcene.


2009 ◽  
Vol 31 (5) ◽  
pp. 34-37 ◽  
Author(s):  
Chris Shaw

Amphibian skin has long been known by humans to possess intriguing biological properties and scientific examination of these secretions has revealed that their components possess a range of medical properties. In Japan and China, toad venom has been used as an expectorant, anti-haemorrhagic, diuretic and cardiac stimulant, and some peptides in the secretions of South American frogs and toads have antibiotic and anticancer properties. In fact, the pharmaceutical industry was built upon the realization of the healing and therapeutic potential of many lead compounds used in ethnic or traditional medicines (e.g. morphine, quinine and aspirin).


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