scholarly journals Evaluation of Psychiatric Disorders in Spouse of Patients with Alcohol Dependence Syndrome

2021 ◽  
pp. 1-5
Author(s):  
Mahesh Tilwani
Keyword(s):  
Alcohol Dependence ◽  
Psychiatric Disorders ◽  
Affective Disorder ◽  
Depressive Episode ◽  
Bipolar Affective Disorder ◽  
Psychiatric Morbidity ◽  
Adjustment Disorder ◽  
International Classification Of Diseases ◽  
Psychiatric Research ◽  
Alcohol Dependence Syndrome

Background and Aim: Alcohol Dependence Syndrome has deleterious consequences not only on the patient with Alcohol Dependence Syndrome but also on the members of his family. The psychopathology in wives of patients with Alcohol Dependence Syndrome is a largely neglected area in psychiatric research. Aim of the present study was to evaluate the frequency and nature of psychiatric disorders in wives of patients with Alcohol Dependence Syndrome. Materials and Methods: A total of 177 wives, 100 wives of patients with Alcohol Dependence Syndrome and 77 wives of patients with Bipolar Affective Disorder- current episode mania were evaluated. Tools used were ICD-10 AM symptom checklist and modules for assessment of psychiatric morbidity and diagnosis was made based on The International Classification of Diseases – (Diagnostic Research Criteria DCR-10). Results: Psychiatric disorders are diagnosed in 75% of the wives of patients with alcohol dependence syndrome out of which 45% have dysthymia, 12% have mild depressive episode, 8% have adjustment disorder- prolonged depressive reaction, 5% have moderate depressive episode and 5% have anxiety disorder unspecified. Conclusion: The present study concludes that the wives of patients with Alcohol Dependence Syndrome have significant psychiatric morbidity when compared to wives of patients with Bipolar Affective Disorder-current episode mania. The most common psychiatric disorder is dysthymia.

Molecular Genetics of Mental Disorders with Particular Reference to Affective Disorders

1997 ◽  
Vol 12 (S2) ◽  
pp. 63s-69s ◽  
Author(s):  
D Souery ◽  
O Lipp ◽  
B Mahieu ◽  
J Mendlewicz
Keyword(s):  
Mental Disorders ◽  
Psychiatric Disorders ◽  
Affective Disorder ◽  
Molecular Genetics ◽  
Present Article ◽  
Affective Disorders ◽  
Trinucleotide Repeat ◽  
Association Studies ◽  
Bipolar Affective Disorder ◽  
Molecular Genetic

SummaryThe present article reviews the recent molecular genetic findings in affective disorders. Results of linkage and association studies are discussed in regard to the main limitations of these approaches in psychiatric disorders. On the whole, linkage and association studies contributed to the localisation of some potential vulnerability genes for Bipolar affective disorder on chromosomes 18, 5, 11, 4, 21 and X. The hypothesis of anticipation in affective disorders is also considered in light of interesting results with trinucleotide repeat mutations.

scholarly journals Study of psychiatric disorders among nepalese patients working abroad and their family members

2012 ◽  
Vol 6 (4) ◽  
pp. 1-6
Author(s):  
B Yengkokpam ◽  
SK Shah ◽  
GR Bhantana
Keyword(s):  
Psychiatric Disorders ◽  
Psychotic Disorders ◽  
Somatoform Disorders ◽  
Bipolar Affective Disorder ◽  
Family Members ◽  
International Classification Of Diseases ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Classification Of Diseases ◽  
Icd 10

This study was carried out among the patients working abroad and their family members, having various psychiatric disorders. 80 patients attending psychiatry OPD between the age of 15 to 65 years both male and female in the period of July 2009 to July 2010 were included. The results were tabulated as per the diagnostic criteria of International Classification of Diseases (ICD-10). Out of total 80 patients, 41 were males and 39 were females, whose husbands were working abroad. 30 cases were of depression,out of which 16 were males and 14 were females.18 cases were having anxiety disorders out of which 5 were males and 13 were females. 12 cases were suffering from psychotic disorders out of which 10 were males and 2 were females.7 cases were having dissociative disorders with 1 male and 6 females.4 cases were having somatoform disorders with 2 males and 2 females.1 male and 1 female were suffering from mania.1 male and 1 female were suffering from bipolar affective disorder. 2 males were alcohol dependent and 2 males were having obsessive compulsive disorder. 1 male was having organic psychosis. Journal of College of Medical Sciences-Nepal,2011,Vol-6,No-4, 1-6 DOI: http://dx.doi.org/10.3126/jcmsn.v6i4.6718

Takotsubo syndrome in bipolar affective disorder with alcohol withdrawal syndrome

2020 ◽  
Vol 13 (10) ◽  
pp. e236070
Author(s):  
Deshwinder Singh Sidhu ◽  
Richard Farrelly ◽  
John Lally
Keyword(s):  
Affective Disorder ◽  
Troponin I ◽  
Epigastric Pain ◽  
Bipolar Affective Disorder ◽  
Alcohol Withdrawal Syndrome ◽  
Takotsubo Syndrome ◽  
History Of ◽  
Alcohol Dependence Syndrome ◽  
Background History ◽  
St Elevation

A 40-year-old woman presented to the emergency department with epigastric pain and agitation. She recently separated from her husband and was consuming 30 units of alcohol daily for 5 days. She had a history of bipolar affective disorder, borderline personality disorder and alcohol dependence syndrome. Investigations revealed the following: elevated troponin I levels, ST elevation, early Q waves and prolonged QTc. Emergency angiogram confirmed Takotsubo’s appearance. Medications with QTc prolongation propensity were held. A multidisciplinary apporach was required. She was discharged 10 days later when medically stabilised. It was later discovered that she died unexpectedly the following month. Takotsubo syndrome is a rare but unique cause of cardiac failure. This case highlights the need to consider the differential of Takotsubo syndrome in people presenting with possible acute ischaemic events, particularly in those with a history of combined emotional and physical stressors and a background history of mood disorder.

P01-246-3Q29 case-control association study of co-morbid migraine in bipolar affective disorder

2011 ◽  
Vol 26 (S2) ◽  
pp. 247-247
Author(s):  
M. Schmoeger ◽  
S. Cohen-Woods ◽  
G. Hosang ◽  
M. Schloegelhofer ◽  
I. Craig ◽  
...  
Keyword(s):  
Association Study ◽  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
International Classification Of Diseases ◽  
Case Control ◽  
Genome Wide ◽  
A Genome ◽  
Co Morbidity ◽  
Classification Of Diseases ◽  
Operational Criteria

According to Oedegaard et al. (2010) the co-morbidity of migraine and bipolar disorder (BPD) is well documented in numerous epidemiological and clinical studies, and there are clear pathophysiological similarities. Interestingly, in a genome-wide scan, Lea et al. (2005) identified a susceptibility locus for a severe heritable form of common migraine on chromosome 3q29. With respect to BPD, a susceptibility region on chromosome 3q29 was identified in a genome-wide linkage scan (Bailer et al. 2002) and follow-up linkage analysis (Schosser et al. 2004). These findings were also supported by further fine-mapping of this region (Schosser et al. 2007). Since 3q29 is among the chromosomal regions implicated in migraine and bipolar linkage studies, the aim of the current study is to test for 3q29 association of migraine in sample of patients with BPD. The sample consists of 463 patients with a diagnosis of BPD (34.63% men, 65.37% women; mean age ± SD: 48.01 ± 11.26), as defined by the Diagnostic and Statistical Manual 4th edition operational criteria (DSM-IV) and the International Classification of Diseases 10th edition operational criteria (ICD-10), derived from the Bipolar Affective Disorder Case Control Study (BACCS). A total of 51 SNPs in the region of the 3q29 were genotyped using Sequenom MassARRAY® iPLEX Gold and tested for association with migraine. The results of this association study investigating the 3q29 region in a sample of patients with BPD will be presented.

Current Approaches to Diagnostics of Bipolar Affective Disorder in Adolescents

2020 ◽  
pp. 69-78
Author(s):  
Leonid Bardenshtein ◽  
Natalia Osipova
Keyword(s):  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
International Classification Of Diseases ◽  
Diagnostic Systems ◽  
Dsm V ◽  
Screening Study ◽  
Classification Of Diseases ◽  
Research Findings ◽  
The Relationship

The review is devoted to diagnosing bipolar affective disorder in adolescence. The article summarizes the domestic and foreign research findings concerning the early disease manifestations, the specific features of the disease course, and the relationship with mental and corporal comorbidity. Special attention is paid to the diagnosis of hypomania, based on the recommendations of modern international diagnostic systems: DSM-V (APA, 2013), and the draft International Classification of Diseases, ICD-11 2019. Early detection of affective disorder in adolescents using screening study methods is shown to be significant.

Postpartum Mania

1979 ◽  
Vol 135 (6) ◽  
pp. 551-554 ◽  
Author(s):  
Arnold Kadrmas ◽  
George Winokur ◽  
Raymond Crowe
Keyword(s):  
Affective Disorder ◽  
Depressive Episode ◽  
Postpartum Period ◽  
Matched Control ◽  
Bipolar Affective Disorder ◽  
Practical Significance ◽  
Control Group ◽  
Matched Control Group ◽  
Theoretical Significance ◽  
Unselected Group

SummaryTwenty-one patients with bipolar affective disorder (20 manic episodes, one depressive episode) during the postpartum period were evaluated. They were compared to an unselected group of women with bipolar histories, as well as to a matched control group. The postpartum group had significantly more Schneiderian symptoms and fewer recurrences of illness within the three-year period after the index admission. There was a notable trend toward postpartum patients having fewer affectively ill relatives than the controls. The practical significance of these findings with regards to lithium therapy is discussed, as is the theoretical significance in terms of heterogeneity of the bipolar syndrome.

scholarly journals Treatment Non-Compliance In Patients Suffering From Schizophrenia And Bipolar Affective Disorder (BPAD): A Comparative Study

2019 ◽  
Vol 8 (2) ◽  
pp. 20-25
Author(s):  
K. Paudel ◽  
S. Subedi
Keyword(s):  
Psychiatric Disorders ◽  
Affective Disorder ◽  
Quality Care ◽  
Bipolar Affective Disorder ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Active Involvement ◽  
Interview Method ◽  
Adherence Scale ◽  
Bipolar Affective Disorders

 Introduction: Non-adherence to appropriately prescribed medication for psychiatric disorders prevents patients from realizing the full benefits of their treatment and negatively impacts on individuals, their families and the healthcare system. Understanding and reducing non-adherence is therefore a key challenge to quality care for patients with psychiatric disorders. This finding highlights the prevalence, consequence of non-adherence and barriers to adherence. Therefore, the main objective of this study was to determine the incidence and factors associated with medication non-compliance among patients suffering from schizophrenia and bipolar affective disorders. Material and Method: This cross-sectional study included 94 schizophrenia and 76 bipolar affective disorder subjects who were visited psychiatric OPD of tertiary level hospital and disproportionate stratified random sampling method. An anonymous socio-demographic as well contributing factor questionnaire pre tested, semi structured pro forma by interview method and a clinical proforma designed by Morisky, the 8-item Morisky Medication Adherence Scale (MMAS-8) were used for data collection. Results: The prevalence of non-compliance was 88%, the independent predictors of non-compliance were; seeking for traditional/spiritual treatment, weight gain as side effects of drugs , increased number of medication (p=0.038), beginning of medication start (p=0.057), unemployment (p=0.059), low level of insight/education (p=0.044), male as gender (p=0.016). Conclusion: Based on the outcome of the study, we recommend the development of psycho-educational programmes on compliance and the active involvement of the relatives and significant others in the management of patients of mentally ill patients.

Duplication 15q14 → pter: a rare chromosomal abnormality underlying bipolar affective disorder

2004 ◽  
Vol 19 (3) ◽  
pp. 179-181 ◽  
Author(s):  
Andreas Reif ◽  
Wolfgang Kress ◽  
Karl Wurm ◽  
Jens Benninghoff ◽  
Bruno Pfuhlmann ◽  
...  
Keyword(s):  
Psychiatric Disorders ◽  
Affective Disorder ◽  
Chromosomal Abnormality ◽  
Reciprocal Translocation ◽  
Bipolar Affective Disorder ◽  
Prader Willi Syndrome ◽  
Dysmorphic Features ◽  
Parietal Lobes ◽  
Pet Scanning

AbstractWe have followed up a patient with 8q24.2 → qter and 15q14 → pter duplication due to a maternal reciprocal translocation, a condition related to Prader-Willi Syndrome. Apart from dysmorphic features, the patient suffered from recurring episodes of bipolar psychosis. Interestingly, PET scanning revealed revealed prominent bilateral hypometabolism in the frontal, temporal, and parietal lobes as well as in the cerebellum. Possible implications of this rare chromosomal abnormality with regards to psychiatric disorders are discussed, with emphasis on recent evidence suggesting chromosome 15q13-15 as a susceptiblity locus for psychosis.

Psychiatric Morbidity and Impact on Hospital Length of Stay Among Hematologic Cancer Patients Receiving Stem-Cell Transplantation

2002 ◽  
Vol 20 (7) ◽  
pp. 1907-1917 ◽  
Author(s):  
Jesús M. Prieto ◽  
Jordi Blanch ◽  
Jorge Atala ◽  
Enric Carreras ◽  
Montserrat Rovira ◽  
...  
Keyword(s):  
Stem Cell ◽  
Length Of Stay ◽  
Stem Cell Transplantation ◽  
Hospital Admission ◽  
Psychiatric Disorders ◽  
Psychiatric Morbidity ◽  
Adjustment Disorder ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Hematologic Cancer

PURPOSE: To determine the prevalence of psychiatric disorders during hospitalization for hematopoietic stem-cell transplantation (SCT) and to estimate their impact on hospital length of stay (LOS). PATIENTS AND METHODS: In a prospective inpatient study conducted from July 1994 to August 1997, 220 patients aged 16 to 65 years received SCT for hematologic cancer at a single institution. Patients received a psychiatric assessment at hospital admission and weekly during hospitalization until discharge or death, yielding a total of 1,062 psychiatric interviews performed. Psychiatric disorders were determined on the basis of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Univariate and multivariate linear regression analyses were used to identify variables associated with LOS. RESULTS: Overall psychiatric disorder prevalence was 44.1%; an adjustment disorder was diagnosed in 22.7% of patients, a mood disorder in 14.1%, an anxiety disorder in 8.2%, and delirium in 7.3%. After adjusting for admission and in-hospital risk factors, diagnosis of any mood, anxiety, or adjustment disorder (P = .022), chronic myelogenous leukemia (P = .003), Karnofsky performance score less than 90 at hospital admission (P = .025), and higher regimen-related toxicity (P < .001) were associated with a longer LOS. Acute lymphoblastic leukemia (P = .009), non-Hodgkin’s lymphoma (P = .04), use of peripheral-blood stem cells (P < .001), second year of study (P < .001), and third year of study (P < .001) were associated with a shorter LOS. CONCLUSION: Our data indicate high psychiatric morbidity and an association with longer LOS, underscoring the need for early recognition and effective treatment.

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