scholarly journals Flummoxed Presentation of Paratyphoid Fever: A Case Report

Author(s):  
Shadan Akhtar ◽  
Lenah Bashir ◽  
Bashir A. Fomda ◽  
Yawar Nissar

Enteric fever remains a major disease burden in developing countries. Paratyphoid fever has been described as a less severe infection than typhoid fever. Salmonella serovar Paratyphi A has been however seen as an increasing problem in many areas in Asia and can cause a disease with severity proportional to that of Salmonella serovar Typhi. Among Asian countries China, India, Indonesia, Pakistan, and Vietnam are considered to be endemic for typhoid. This case describes female infant presenting with long standing lymphadenopathy in the cervical and axillary area. Considering the duration of clinical feature she was investigated for Tuberculosis and Hodgkins lymphoma. The extensive course of investigations ruled out both. Sampling of gastric aspirate in pursuit of diagnosing tuberculosis incidentally revealed Salmonella Paratyphi B repeatedly as the cause of the generalized lymphadenopathy.This is a first report which describes such a case in the best of our knowledge.

2013 ◽  
Vol 1 (2) ◽  
pp. 103-105
Author(s):  
A Nepal ◽  
R Acharya ◽  
AR Ojha ◽  
S Sah

Enteric fever is a common cause of morbidity and hospital admission in developing countries. This can sometimes be complicated by rare complications like hepatitis. One should be careful when selecting antibiotics like ceftriaxone in such children which can cause biliary stasis. Our case of enteric hepatitis treated with ceftriaxone developed a prolonged jaundice with biliary stasis as a result of antibiotic therapy. DOI: http://dx.doi.org/10.3126/jkmc.v1i2.8147 Journal of Kathmandu Medical College, Vol. 1, No. 2, Oct.-Dec., 2012: 103-105


Author(s):  
Anggraini Alam ◽  
Sri Sudarwati ◽  
Dzulfikar Djalil Lukmanul Hakim ◽  
Sally Mahdiani

We report a case of a 10-month infant with dual severe infection of COVID-19 and dengue fever who was admitted to the hospital with an influenza-like illness. The patient experienced severe conditions of COVID-19 and dengue fever with shock followed by disseminated intravascular coagulation. The standard of COVID-19 care was given coupled with fluid resuscitation and blood transfusion. The pitfalls of this case are how to differentiate the clinical manifestation of dengue fever in a patient with confirmed COVID-19; the difficulty to monitor the dengue course of illness of the patient in the COVID-19 isolation room; and to differentiate the severe dengue from the multisystem inflammatory syndrome-C when the patient was in critical condition. The infant recovered without sequale, but the management of new probable cases must be improved more thoroughly, especially during dengue peak period in tropical and developing countries such as Indonesia.


Author(s):  
S. Aarifaa ◽  
Kaliannan Mayilananthi ◽  
Durga Krishnan ◽  
V. R. Mohan Rao ◽  
Praveen Srinivas

Typhoid fever is an endemic infection in developing countries like India. Oral manifestations of enteric fever and typhoid tonsillitis have rarely been reported in the literature.   We report a 20 year old male, showing tonsillitis to be an integral part of clinical presentation of typhoid fever.The patient presented with fever, throat pain and oral ulcers. Blood culture and swab from tonsils showed significant growth of Salmonella typhi.This case report adds light to tonsillitis as a rare clinical manifestation of typhoid fever.


2019 ◽  
Vol 5 (3) ◽  
Author(s):  
Avinash Rajan ◽  
Udhayasankar Ranganathan ◽  
Mangaiyarkarasi Thiyagarajan ◽  
Sunil Shivekar ◽  
Gopal Rangasamy

1976 ◽  
Vol 76 (1) ◽  
pp. 83-89 ◽  
Author(s):  
J. C. M. Sharp ◽  
C. S. Heymann

SUMMARYA review of 194 cases of enteric infection in Scotland during 1967–74, is reported. Diagnosis was confirmed by the laboratory isolation of Salmonella typhi (64 cases), S. paratyphi A (3) and S. paratyphi B (127), from blood or faeces; 174 persons were clinically ill and 20 were symptomless infections.Most patients (81·0%) were under 35 years of age, with the highest incidence occurring among young adults of 15–24 years, many of whom had been travelling overseas. One-third of all cases (65) were imported infections; the remaining 129 patients had not been outside the United Kingdom. A significantly greater proportion of typhoid infection (54·7%) was contracted overseas, in contrast to paratyphoid B with only one-fifth of cases (21·2%) being imported; all three cases of paratyphoid A were imported. The geographic distribution of origin of imported infections is discussed, along with the frequency of organisms belonging to different phage types.Two deaths occurred, one of which was the result of complications of paratyphoid fever. All other patients responded well to treatment, although two persons continued to excrete and became chronic carriers.A few examples are given of episodes of particular epidemiological interest.It is expected that in future years there will be a continued increase in the proportion of imported infections as more persons travel overseas, concurrent with the continuing decline in the number of chronic carriers resident in the British Isles.


1988 ◽  
Vol 27 (3) ◽  
pp. 336-338
Author(s):  
Muhammad Hussain Malik

The need to enhance their economic relations with each other has long been felt by developing countries. However, their efforts in this regard have met with limited success. One of the reasons for this could be that not much serious work has been done to understand the complexities and possibilities of economic relations of developing countries. The complementarities which exist among the economies of these countries remain relatively unexplored. There is a lack of concrete policy proposals which developing countries may follow to achieve their often proclaimed objective of collective self-reliance. All this needs serious and rigorous research efforts. In this perspective, the present study can be considered as a step in the right direction. It examines trade and other economic relations of developing countries of two regions of Asia-South Asian countries and member countries of the Association of Southeast Asian Nations (ASEAN). The study also explores ways and means to improve economic relations among these countries


Author(s):  
Deepak Kaul ◽  
Farahnaz Muddebihal ◽  
Mohammed Anwar Ul Haque Chand

Osteomyelitis of maxillofacial skeleton is common in developing countries such as India. This case report describes successful surgical treatment of chronic suppurative osteomyelitis {CSO} of the mandible of a 35yr old female. The precipitating factor was thought to be eventful extraction in the {left } posterior body at the inferior border of mandible. Methods: Presurgical course of antibiotics ( Amoxycillin and metronidazole for 7 days and later followed by doxycycline for 1 month).Surgical debridement of the affected bone and reinforcing it with reconstruction plate using AO principles was done . Patient was kept on a high nutrient diet consisting of proteins. Conclusion: The case report demonstrates the typical features of CSO . The combination of the antibiotics therapy and surgical debridement was successful in the treatment of chronic suppurative osteomylitis.


2020 ◽  
Vol 20 (12) ◽  
pp. 1118-1132
Author(s):  
Sidra Saleem ◽  
Haroon Ahmed ◽  
Tooba Siddiqui ◽  
Seyma Gunyakti Kilinc ◽  
Aisha Khan ◽  
...  

Schistosomiasis is a chronic parasitic disease caused by a trematode blood fluke of the genus Schistosoma that belongs to the Schistosomatidae family. It is a neglected disease in different regions of Asia. In this review, 218 articles (between 2000 and 2017) related to the topic were collected from PubMed and Google scholar and reviewed. After thoroughly reading collected articles, due to irrelevant topic requirements, 94 articles were excluded. Articles that have data associated with Asian regions are considered. In Asia, the disease is prevalent in China, Philippines, Indonesia, Yemen, Nepal and Laos, etc. While in Pakistan, India and Bangladesh, the disease is not endemic and very few cases were reported. The disease was eliminated from Japan and Iran. The current review highlights the geographical distribution among Asian countries, transmission patterns, diagnosis, control strategies based on the use of anthelmintic plants and management practices implemented in Asia for the control of schistosomiasis. However, new implementations to treat schistosomiasis in humans should be proved to eliminate the disease finally in the future. This review emphasizes the biological control of schistosomiasis for the eradication of the disease from Asia in the near future.


2021 ◽  
Vol 9 ◽  
pp. 232470962199220
Author(s):  
Balraj Singh ◽  
Parminder Kaur ◽  
Michael Maroules

Immune checkpoint inhibitors have emerged as a novel treatment in a wide variety of malignancies; however, it is associated with a distinctive array of side effects known as immune-related adverse events. Hyperprogression is defined as an accelerated growth of disease burden in patients treated with immunotherapy. Limited literature is available regarding hyperprogression in hepatocellular cancer. We report a case of a 36-year-old male with no past medical history who presented with nausea, vomiting, and abdominal pain and was diagnosed with unresectable hepatocellular cancer and thereby started on atezolizumab and bevacizumab. The patient got only 1 cycle of treatment and unfortunately had hyperprogression of disease.


2021 ◽  
Vol 9 (4) ◽  
pp. 853
Author(s):  
Miriam Cordovana ◽  
Norman Mauder ◽  
Markus Kostrzewa ◽  
Andreas Wille ◽  
Sandra Rojak ◽  
...  

Typhoidal and para-typhoidal Salmonella are major causes of bacteraemia in resource-limited countries. Diagnostic alternatives to laborious and resource-demanding serotyping are essential. Fourier transform infrared spectroscopy (FTIRS) is a rapidly developing and simple bacterial typing technology. In this study, we assessed the discriminatory power of the FTIRS-based IR Biotyper (Bruker Daltonik GmbH, Bremen, Germany), for the rapid and reliable identification of biochemically confirmed typhoid and paratyphoid fever-associated Salmonella isolates. In total, 359 isolates, comprising 30 S. Typhi, 23 S. Paratyphi A, 23 S. Paratyphi B, and 7 S. Paratyphi C, respectively and other phylogenetically closely related Salmonella serovars belonging to the serogroups O:2, O:4, O:7 and O:9 were tested. The strains were derived from clinical, environmental and food samples collected at different European sites. Applying artificial neural networks, specific automated classifiers were built to discriminate typhoidal serovars from non-typhoidal serovars within each of the four serogroups. The accuracy of the classifiers was 99.9%, 87.0%, 99.5% and 99.0% for Salmonella Typhi, Salmonella Paratyphi A, B and Salmonella Paratyphi C, respectively. The IR Biotyper is a promising tool for fast and reliable detection of typhoidal Salmonella. Hence, IR biotyping may serve as a suitable alternative to conventional approaches for surveillance and diagnostic purposes.


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