Literature Riview : Penerapan Kompres Air Hangat Untuk Menurunkan Suhu Tubuh Pada Pasien Demam Thypoid

Typhoid fever is a systemic infection caused by salmonella enterica bacteria, especially its derivative variants, namely salmonella typhi, paratyphi A, paratyphi B, paratyphi C. These germs attack the digestive tract, especially in the stomach and intestines, nursing problems that often occur in patients with typhoid fever, namely hyperthermia. Hyperthermia is a condition in which an individual has an increase in body temperature above 37.8 C parrectal due to external factors. A warm compress is a procedure used to improve control of body heat loss through evaporation and conduction which is usually performed on patients who have a high fever. The purpose of scientific papers is to see an overview of the application of warm compresses to reduce body temperature in typhoid fever patients. The method is carried out by searching several research journals entitled about the application of warm water compresses to reduce body temperature in typhoid fever patients. The results obtained after the action of warm water compresses, body temperature decreased within normal limits. The conclusion of this scientific paper is that the action of warm water compresses can reduce body temperature in patients with typhoid fever. Suggestions for nurses are expected to apply warm compresses to reduce body temperature in typhoid fever patients.Keywords: Key words: typhoid fever, hyperthermia, warm water compress AbstrakDemam typhoid adalah infeksi sistemik yang di sebabkan oleh bakteri salmonella enterika, khususnya varian-varian turunannya, yaitu salmonella typhi, paratyphi A, paratyphi B, paratyphi C. Kuman-kuman tersebut menyerang saluran pencernaan, terutatama di perut dan usus masalah keperawatan yang sering terjadi pada pasien demam tifoid yaitu hipertermia . Hipertermi adalah suatu keadaan dimana seorang individu mengalami peningkatan suhu tubuh di atas 37,8⁰C parrektal karena factor eksternal. Kompres air hangat adalah prosedur yang di gunakan untuk meningkatkan control kehilangan panas tubuh melalui evaporasi dan konduksi yang biasanya di lakukan pada pasien yang mengalami demam tinggi. Tujuan dari karya tulis ilmiah adalah untuk mengetahui gambaran tentang penerapan kompres air hangat untuk menurunkan suhu tubuh pada pasien demam thypoid. Metode yang dilakukan dengan mencari beberapa jurnal penelitian berjudul tentang penerapan kompres air hangat untuk menurunkan suhu tubuh pada pasien demam thypoid. Hasil yang didapatkan setelah dilakukan tindakan kompres air hangat suhu tubuh mengalami penurunan dalam batas normal. Kesimpulan karya tulis ilmiah ini bahwa tindakan kompres air hangat dapat menurunkan suhu tubuh pada pasien demam thypoid. Saran bagi perawat diharapkan dapat menerapkan tindakan kompres air hangat untuk menurunkan suhu tubuh pada pasien demam thypoid.Kata kunci: Demam Thypoid, Hipertermi, Kompres air hangat

Genome-wide analysis provides a deeper understanding of the population structure of the Salmonella enterica serotype Paratyphi B complex in Bangladesh

The Salmonella enterica serotype Paratyphi B complex causes a wide range of diseases, from gastroenteritis to paratyphoid fever, depending on the biotypes Java and sensu stricto. The burden of Paratyphi B biotypes in Bangladesh is still unknown, as these are indistinguishable by Salmonella serotyping. Here, we conducted the first whole-genome sequencing (WGS) study on 79 Salmonella isolates serotyped as Paratyphi B that were collected from 10 nationwide enteric disease surveillance sites in Bangladesh. Placing these in a global genetic context revealed that these are biotype Java, and the addition of these genomes expanded the previously described PG4 clade containing Bangladeshi and UK isolates. Importantly, antimicrobial resistance (AMR) genes were scarce amongst Bangladeshi S. Java isolates, somewhat surprisingly given the widespread availability of antibiotics without prescription. This genomic information provides important insights into the significance of S. Paratyphi B biotypes in enteric disease and their implications for public health.

IDENTIFIKASI BAKTERI Salmonella sp. PADA PENDERITA DEMAM TIFOID ANAK USIA 5-14 TAHUN DENGAN METODE WIDAL TEST DI RUMAH SAKIT ADVENT MEDAN TAHUN 2018

Demam tifoid merupakan suatu penyakit sistemik akut yang disebabkan oleh Salmonella typhi, Salmonella paratyphi A, Salmonella paratyphi B dan Salmonella paratyphi C. Penularan demam tifoid terjadi secara fekal-oral melalui makanan dan minuman yang terkontaminasi yang masuk kedalam tubuh.Pada anak-anak demam tifoid dapat terjadi akibat kurang memperhatikan kebersihan diri dan kebiasaan jajan yang sembarangan sehingga dapat menyebabkan tertular penyakit demam tifoid.Telah dilakukan penelitian terhadap 10 serum penderita demam tifoid anak usia 5-14 tahun di Rumah Sakit Advent Medan, dengan identifikasi bakteri Salmonellamelalui Uji Widal.Hasil yang telah di peroleh yaitu 1 orang pasien positif terhadap Salmonella typhii;1 orang pasien positif terhadap Salmonella typhii dan Salmonella paratyphii B; 3 orang pasien positif terhadap Salmonella typhii, Salmonella paratyphii B dan Salmonella paratyphii C; 2 orang pasien positif terhadap Salmonella typhii, Salmonella paratyphii A dan Salmonella paratyphii C; 1 orang pasien positif terhadap Salmonella paratyphii A, Salmonella paratyphii B dan Salmonella paratyphii C dan2 orang pasien yang positif terhadap Salmonella typhii, Salmonella paratyphii A, Salmonella paratyphii B dan Salmonella paratyphii C. Dalam penelitian ini, sebagian besar pasien positif terhadap lebih dari 1 antigen Salmonella, hal ini dapat terjadi karena adanya reaksi silang sebelumnya dengan antigen antara spesies Salmonella yang sama yang memiliki antigen O faktor 12 atau pernah terinfeksi dahulu dengan salah satu spesies Salmonella.

Classification of Salmonella enterica of the (Para-)Typhoid Fever Group by Fourier-Transform Infrared (FTIR) Spectroscopy

Typhoidal and para-typhoidal Salmonella are major causes of bacteraemia in resource-limited countries. Diagnostic alternatives to laborious and resource-demanding serotyping are essential. Fourier transform infrared spectroscopy (FTIRS) is a rapidly developing and simple bacterial typing technology. In this study, we assessed the discriminatory power of the FTIRS-based IR Biotyper (Bruker Daltonik GmbH, Bremen, Germany), for the rapid and reliable identification of biochemically confirmed typhoid and paratyphoid fever-associated Salmonella isolates. In total, 359 isolates, comprising 30 S. Typhi, 23 S. Paratyphi A, 23 S. Paratyphi B, and 7 S. Paratyphi C, respectively and other phylogenetically closely related Salmonella serovars belonging to the serogroups O:2, O:4, O:7 and O:9 were tested. The strains were derived from clinical, environmental and food samples collected at different European sites. Applying artificial neural networks, specific automated classifiers were built to discriminate typhoidal serovars from non-typhoidal serovars within each of the four serogroups. The accuracy of the classifiers was 99.9%, 87.0%, 99.5% and 99.0% for Salmonella Typhi, Salmonella Paratyphi A, B and Salmonella Paratyphi C, respectively. The IR Biotyper is a promising tool for fast and reliable detection of typhoidal Salmonella. Hence, IR biotyping may serve as a suitable alternative to conventional approaches for surveillance and diagnostic purposes.

A Study of Paratyphoid Fever in Bulgarian Children

Objective. To study both the molecular discrimination of D-tartrate fermenting and non-fermenting strains of Salmonella enterica subsp. enterica serotype Paratyphi B isolated from patients with paratyphoid fever and the clinical course of this disease. Materials and methods. The isolates examined were from children aged 3 months to 9 years. A total of 33 Salmonella strains were serotyped as Salmonella Paratyphi B, with an antigenic formula based on O- and H- antigens: 1,4, [5], 12: b: 1,2 by Kauffmann–White classification. Results. Multiplex PCR analysis confirmed all tested strains as d-tartrate fermenting (dT+), also referred to as variant Java. Discussion. We found that the most common cause of paratyphoid fever among children in Bulgaria is variant Java Salmonella Paratyphi B. Most children had classic symptoms of acute gastroenteritis – fever, watery diarrhea and vomiting.

Isolation, identification and some characteristics of two lytic bacteriophages against Salmonella enterica serovar Paratyphi B and S. enterica serovar Typhimurium from various food sources

ABSTRACT Salmonellosis is an important worldwide food-borne disease. Increasing resistance to Salmonella spp. has been reported in recent years, and now the prevalence of multidrug-resistant Salmonella spp. is a worldwide problem. This necessitates alternative approaches like phage therapy. This study aimed to isolate bacteriophages specific for Salmonella enterica serovar Paratyphi B and S. enterica serovar Typhimurium isolated from different sources (chicken meat, beef and eggshells). The antibiotic resistance profiles of the bacteria were determined by phenotypic and genotypic methods. The prevalence of extended-spectrum β-lactamase genes was examined by polymerase chain reaction. In total, 75% of the isolated Salmonella strains were resistant to tetracycline, whereas 70% of them were resistant to azithromycin. All of the isolates from beef were resistant to nalidixic acid. The most common extended-spectrum β-lactamase genes among the isolates were blaSHV (15%) followed by blaTEM (10%) and blaCTX (5%). Two specific bacteriophages were isolated and characterized. The host range for vB_SparS-ui was Salmonella Paratyphi B, S. enterica serovar Paratyphi A and S. enterica, while that for vB_StyS-sam phage was Salmonella Typhimurium and S. enterica serovar Enteritidis. The characteristics of the isolated phages indicate that they are proper candidates to be used to control some foodstuff contaminations and also phage therapy of infected animals.

Prevalence and Molecular Characterization of Salmonella Isolated from Broiler Farms at the Tolima Region—Colombia

Salmonella is an important animal and human pathogen responsible for Salmonellosis, and it is frequently associated with the consumption of contaminated poultry products. The aim of this study was to estimate the prevalence of Salmonella in the poultry farms and to determine the genetic relationship. A total of 135 samples collected from fifteen broiler farms, including cloacal, feed, water, environmental and farm operator faeces samples were subjected to microbiological isolation. Molecular confirmation of Salmonella isolates was carried out by amplification of the invA gene, discrimination of d-tartrate-fermenting Salmonella isolates using multiplex PCR, and subsequently analysed by pulsed-field gel electrophoresis (PFGE). A survey questionnaire was conducted to identify potential risk factors for Salmonella presence in broiler farms. The prevalence of Salmonella at the farm level was 26.67%, and Salmonella isolates were serotyped as S. Paratyphi B and all isolates were d-tartrate-fermenting (dT+). PFGE showed three highly similar clusters and one significantly different Salmonella isolate. S. Paratyphi B continued to be present in different links of the poultry chain in the Tolima region, and identification of its main source is necessary to control its dissemination.

Genotypic Characterization of Antimicrobial Resistant Salmonella spp. Strains from Three Poultry Processing Plants in Colombia

The poultry industry in Colombia has implemented several changes and measures in chicken processing to improve sanitary operations and control pathogens’ prevalence. However, there is no official in-plant microbial profile reference data currently available throughout the processing value chains. Hence, this research aimed to study the microbial profiles and the antimicrobial resistance of Salmonella isolates in three plants. In total, 300 samples were collected in seven processing sites. Prevalence of Salmonella spp. and levels of Enterobacteriaceae were assessed. Additionally, whole-genome sequencing was conducted to characterize the isolated strains genotypically. Overall, the prevalence of Salmonella spp. in each establishment was 77%, 58% and 80% for plant A, B, and C. The mean levels of Enterobacteriaceae in the chicken rinsates were 5.03, 5.74, and 6.41 log CFU/mL for plant A, B, and C. Significant reductions were identified in the counts of post-chilling rinsate samples; however, increased levels were found in chicken parts. There were six distinct Salmonella spp. clusters with the predominant sequence types ST32 and ST28. The serotypes Infantis (54%) and Paratyphi B (25%) were the most commonly identified within the processing plants with a high abundance of antimicrobial resistance genes.