Predictive Risk Factors for Post Tonsillectomy Hemorrhage in Children

Objective: To assess the risk factors which determine the magnitude of post-tonsillectomy hemorrhage. Study Design: Prospective cross sectional study. Setting: A study carried out at otolyrangical unit at a tertiary care Isra University hospital Hyderabad, from June 2018 to April 2019. Materials and Methods: 110 pediatric patients age 5-17 years were included in this study. We administrated a structured questionnaire to parents of the patients. We selected cases for tonsillectomy as per criteria of the American Academy of Otolaryngology Head and Neck Surgery (AAO-HNS). Those patients with a history of recurrent tonsillitis presented at the otolaryngology department were included. Patients with a history of use of anticoagulant therapy, obstructive sleep apnea, patients with a history of a bleeding disorder, and patients not giving consent were excluded. We diagnosed patients selected for tonsillectomy included with recurrent tonsillitis, peri-tonsillar hypertrophy, and tonsillar hypertrophy. Patients were observed and followed for postoperative hemorrhage. Data were analyzed by using Statistical Package for Social Sciences version 21 (SPSS 21). Results: Among 110 children included in the study, 41.8% patients were in the age group of 5-10 years, 30% were in the age group of 11-15 years and 28.2% were over 15 years. Among 110 patients 21.8% underwent tonsillectomy were diagnosed as recurrent tonsillitis, 19% were diagnosed as having tonsillar hypertrophy, 40.0% were suffering from both recurrent tonsillitis and tonsillar hypertrophy and 19.2% had peritonsillar hypertrophy. This shows that 14.5% were admitted to the hospital after 1-5 days, 58.1% developed post-tonsillectomy hemorrhage after 6-10 days and 27.2% developed post-tonsillectomy hemorrhage after 10 days. Conclusion: We conclude that age >10 years was significant predictive risk factors for post-tonsillectomy hemorrhage among children who undergo tonsillectomy.

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PREVALENCE OF NAFLD AMONG HEALTHY LIVER DONORS

10.36106/ijsr/8024686 ◽

2021 ◽

pp. 46-48

Author(s):

Muzaffer Rashid Shawl ◽

Fahad ul Islam Mir ◽

Saad Abdul Rahman ◽

Anil C Anand ◽

Manav Wadhawan ◽

...

Keyword(s):

Fatty Liver ◽

Tertiary Care ◽

Cross Sectional Study ◽

Western World ◽

Care Hospital ◽

Cross Sectional ◽

Obstructive Sleep ◽

History Of ◽

Healthy Liver ◽

Liver Donors

NAFLD is hepatic pandemic of the twenty rst century, being leading cause of chronic hepatic disease in western world. We did a cross sectional study to nd out prevalence of NAFLD among prospective healthy liver donors at a tertiary care hospital at New Delhi, India over a period from June 2014 to March 2016. 124 apparently healthy prospective liver donors were selected. Exclusion criteria were set to exclude all those who had signicant history of alcohol intake (dened as greater than 30g/day for men and greater than 20g/day for women over last two years), Hepatitis B or C infection, severe surgical weight loss or emaciation, Obstructive Sleep Apnea, Celiac disease, history of drug intake known to cause hepatic steatosis. Out of 124 prospective liver donors included in this study, 29 (23%) donors were found to have fatty liver on USG abdomen; 38 (31%) donors had fatty liver on unenhanced CTof the abdomen (LAI of ≤ 5 HU); 61 (49%) donors had fatty liver on magnetic resonance.

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Incidence and Risk Factors for Severe Dehydration in Hospitalized Children in Ujjain, India

10.20944/preprints201912.0205.v2 ◽

2020 ◽

Author(s):

Abhishek Sharma ◽

Aditya Mathur ◽

Cecilia Stålsby Lundborg ◽

Ashish Pathak

Keyword(s):

Risk Factors ◽

Tertiary Care ◽

World Health ◽

Respiratory Pattern ◽

Care Hospital ◽

Severe Dehydration ◽

Cross Sectional ◽

Oral Rehydration ◽

History Of ◽

Independent Risk Factors

Diarrhoea contributes significantly in the under-five childhood morality and mortality worldwide. This cross-sectional study was carried out in a tertiary care hospital in Ujjain, India from July 2015 to June 2016. Consecutive children aged 1 month to 12 years having “some dehydration” and “dehydration” according to World Health Organization classification were eligible to be included in the study. Other signs and symptoms used to assess severe dehydration were capillary refill time, urine output, and abnormal respiratory pattern. A questionnaire was administered to identify risk factors for severe dehydration, which was the primary outcome. Multivariate logistic regression modeling was used to detect independent risk factors for severe dehydration. The study included 332 children, with mean ± standard deviation age of 25.62 ± 31.85 months; out of which, 70%(95% confidence interval [CI] 65 to 75) were diagnosed to have severe dehydration. The independent risk factors for severe dehydration were: child not exclusive breast fed in the first six months of life (AOR 5.67, 95%CI 2.51 to 12.78; p<0.001), history of not receiving oral rehydration solution before hospitalization (AOR 1.34, 95%CI 1.01 to 1.78; p=0.038), history of not receiving oral zinc before hospitalization (AOR 2.66, 95%CI 1.68 to 4.21; p<0.001) and living in overcrowded conditions (AOR 5.52, 95%CI 2.19 to 13.93; p<0.001). The study identified many risk factors associated with severe childhood dehydration; many of them are modifiable though known and effective public health interventions.

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Hepatitis C in pregnancy: an observational study highlighting its association with maternal parameters

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20195941 ◽

2019 ◽

Vol 8 (1) ◽

pp. 344

Author(s):

Bushra . ◽

Ambreen Ghori ◽

Azra Ahmed ◽

Najma Dalwani ◽

Mushtaque Ali Shah ◽

...

Keyword(s):

Risk Factors ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Previous History ◽

Cross Sectional Study ◽

University Hospital ◽

Prior History ◽

Singleton Pregnancy ◽

Cross Sectional ◽

History Of

Background: Pregnancy is a very crucial time in a woman’s life. In this period of time, not only multiple physiological alterations effect the usual health status but also makes women more vulnerable to contract infection and face negative sequalae. Hepatitis C, a blood borne viral infection serve the similar fate when encountered by pregnant ladies. This study is based on exploring the prevalence of the Hepatitis C virus seropositivity among pregnant population. Moreover, we also evaluated the major risk factors leading to the infection in these mothers. Besides this, infected mothers were studied for their pregnancy outcomes.Methods: In this study 114 pregnant females were observed for this cross-sectional study. It was conducted in Gynecology Unit- 1, Liaquat University Hospital Hyderabad, for the period of January 2017 to July 2017. Chi square test was applied for statistical analysis on SPSS version 16. The criteria for enrollment in the study was set to be a pregnant lady belonging to age group 20-35 years; having singleton pregnancy; was a booked case at the hospital with compliant to antenatal follow ups; admitted to the labor room for delivery. All the non-pregnant ladies, whom had co morbid conditions such as hypertension or diabetes or had infected with hepatitis B or D were excluded from the study. Furthermore, pregnant ladies with multiple gestion or those who were either diagnosed of hepatitis C prior to conceive or had a previous history of hepatitis C were also excluded.Results: Present study revealed that out of 114, 10(8.8%) pregnant ladies were found seropositive for Hepatitis C virus. Prior history for transfusion of blood was the Foremost risk factor discovered, with 60.5% women reported this. History of surgery was the 2nd commonest factor and 43.9% had this in their medical records. On the other hand, only 8.8% women gave the history for previous evacuation. While observing pregnancy outcomes, we found 48.2% neonates had low birth weight, 41.2% were born preterm and 21.1% had low APGAR score.Conclusions: In a nutshell hepatitis c is prevalent in the pregnant population of this region and showing its effects in the form of compromised pregnancies. History of blood transfusion and previous surgery were found to be chief risk factors in the study.

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HEPATITIS “C”

The Professional Medical Journal ◽

10.29309/tpmj/2016.23.09.1699 ◽

2016 ◽

Vol 23 (09) ◽

Author(s):

Muhammad Iqbal ◽

Adnan Ahmed ◽

Muhammad Rafique Hingoro

Keyword(s):

Hepatitis C ◽

Tertiary Care ◽

Cross Sectional Study ◽

University Hospital ◽

Age Group ◽

Sectional Study ◽

Cross Sectional ◽

Grade 3 ◽

Chronic Hcv ◽

Study Setting

Objectives: To determine incidence of steatosis in non-responder casesof chronic HCV. Study Design: Cross-sectional study. Setting: Tertiary Care Sanatorium inMedicine Department of LIAQUAT University Hospital Hyderabad/Jamshoro. Period: 26-9-2011to 25 August 2012. Material & Methods: Total 144 non-responders cases of Hepatitis C wereintegrated. Both gender, age 18 to 50 yrs, chronic HCV non-responder cases as well as cases fitfor hepatic biopsy were integrated in study. Grading of Inflammation was carried out as indicatedby histopathological measures. Results: Mean age was 48.5 + 5.2years. Uppermost prevalenceof chronic HCV disease was 65(45.13%) at 41 to 50 years age interval whereas 42(29.1%) caseswere noticed in 31 to 40 yrs age group and 25(17.3%) cases were observed in 20 to 30 yearsof young age group. In this study hepatic steatosis occurrence was observed in 103 (71.5%)cases and these were categories as: grade 1, grade 2, grade 3, as (<33%) 45/103(43.68%), (33to 66%) 35/103(33.98%), (>66%) 23/103(22.33%) respectively. Conclusion: Hepatic steatosisis a important risk factor the cases of HCV to decreased response to antiviral therapy and forprogression toward fibrosis as observed in cases related to metabolic steatosis.

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Metastatic Spreading of Community AcquiredStaphylococcus aureusBacteraemia

Case Reports in Infectious Diseases ◽

10.1155/2011/234018 ◽

2011 ◽

Vol 2011 ◽

pp. 1-5

Author(s):

Giovanna Fabio ◽

Maria Carrabba ◽

Luca Mellace ◽

Cinzia Hu ◽

Diego Spagnoli ◽

...

Keyword(s):

Risk Factors ◽

Epidural Abscess ◽

Tertiary Care ◽

Skin Lesions ◽

University Hospital ◽

Serious Infection ◽

History Of ◽

Associated Risk Factors ◽

Healthcare Associated ◽

And Control

A 29-year-old woman presented to the Fondazione IRCCS “Cà Granda” Ospedale Maggiore, a tertiary care university hospital in Milan (Italy), with skin lesions, fever, myalgia, joint pain and swelling, and a one-week history of low back pain. The diagnosis wasStaphylococcus aureus(S. aureus) bacteraemia spreading to skin, bones, and joints and a lumbosacral epidural abscess L5-S2. Neither initial focus nor predisposing conditions were apparent. The antibiotic therapy was prolonged for six-weeks with the resolution of fever, skin lesions, articular inflammation, and the epidural abscess. Community-acquiredS. aureusinfections can affect patients without traditional healthcare-associated risk factors, and community acquisition is a risk-factor for the development of complications. Raised awareness ofS. aureusbacteraemia, also in patients without healthcare-associated risk factors, is important in the diagnosis, management, and control of this infection, because failure to recognise patients with serious infection and lack of understanding of empirical antimicrobial selection are associated with a high mortality rate in otherwise healthy people.

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Frequency of Backache and its Management in Pregnant Women Attending IUH OPD

10.53350/pjmhs2115113441 ◽

2021 ◽

Vol 15 (11) ◽

pp. 3441-3443

Author(s):

Uzma Parveen ◽

Zahida Parveen Brohi ◽

Aneela Sadaf

Keyword(s):

Pregnant Women ◽

Treatment Options ◽

Cross Sectional Study ◽

University Hospital ◽

Age Group ◽

Sectional Study ◽

Cross Sectional ◽

History Of ◽

Keywords Pregnancy ◽

Patient Department

Objective: Frequency of backache and its treatment among pregnant women attending Isra University Hospital (IUH) OPD. Material and methods: This cross-sectional study was conducted at Out patient’s department of obstetrics\Gynaecology Isra hospital Hyderabad from February 2019 to Augusts 2019. A total of 80 pregnant women irrespective of their age, marital and literary status, visiting out-patient department of Isra University were included. All the females were assessed regarding backache and its treatment at gynaecological OPD. All the information was recorded via study proforma. Data was analyzed via SPSS version 20. Results: A total of 180 pregnant women were studied, and most of the women 40% were in age group of 31-40 years. Out of all, 22.2% women were primigravida, 40.6% were multigravidas and 36.7% women were grand multigravidas. The history of backache before pregnancy was among 20% of the females and 62.2% of women had developed backache during pregnancy, while 12.8% women had no complaint of backache. Out of 121 females who had backache during pregnancy, 28.30% had an onset of pain during 1st trimester, in 23.30% during 2nd trimester and in 48.30% during 3rd trimester of pregnancy. Out of all 32.20% women got relieved by taking rest, 63.90% women took analgesics as a treatment measure and 3.3% women took some other treatment options. Conclusion: It was observed that the more than 60% of all pregnant women experienced backache and mostly during 3rd trimester. Most of the females took treatment in the form of analgesics and some women got relieved by taking rest. Keywords: Pregnancy, backache, Management

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0910 Prevalence And Risk Factors Of Obstructive Sleep Apnea Syndrome In 3-14 Yearsold Children In Beijing: A Cross-sectional Surveyabstract

SLEEP ◽

10.1093/sleep/zsaa056.906 ◽

2020 ◽

Vol 43 (Supplement_1) ◽

pp. A346-A346

Author(s):

W Wei

Keyword(s):

Risk Factors ◽

Obstructive Sleep Apnea ◽

Sleep Apnea ◽

Obstructive Sleep Apnea Syndrome ◽

Sleep Apnea Syndrome ◽

Cross Sectional ◽

Obstructive Sleep ◽

Positive Rate ◽

History Of ◽

Apnea Syndrome

Abstract Introduction To explore the prevalence and risk factors of obstructive sleep apnea syndrome (OSAS) in 3-14 years old children in Beijing. Methods A cross-sectional study of random stratified cluster sampling was conducted on 3-14 years old children and adolescents in Beijing. The preliminary screening was completed through Pediatric Sleep Questionnaire (PSQ) investigation and the diagnosis of OSAS was conducted by polysomnography. Results After random sampling, a total of 11 kindergartens, 7 primary schools and 8 junior high schools from 7 districts of Beijing were involved in the survey. A total of 11420 questionnaires were sent out, and 10743 (94.07%) were recovered. The final effective data were 9198 (effective response rate 85.62%). The age of the investigated children was 8.8±3.8 years. PSQ positive rate was 8.86% (95CI 8.28-9.44%). With diagnostic criteria AHI≥5, the estimated prevalence of OSAS in Beijing children was 5.90% (95%CI 3.72-8.28%); with ICSD-3 diagnostic criteria (OAHI>1), the estimated prevalence was 8.08% (95% CI 5.74-10.62%). Overweight (OR=3.13), frequent allergic rhinitis (OR=6.80) and family snoring history (OR=6.14) were important risk factors for children’s OSAS. Conclusion PSQ was used in Beijing children’s OSAS epidemiological survey with good reliability and validity. The positive rate of the PSQ screening was 8.86% (95CI 8.28-9.44%);the estimated prevalence of OSAS in children aged 3-14 years in Beijing was 5.90% (95%CI 3.72-8.28%) with criteria AHI≥5 and 8.08% (95%CI 5.74-10.62%) with criteria OAHI>1, respectively. Gender, BMI, history of ENT and family history of snoring were important risk factors for children’s OSAS. Support This work was supported by Beijing Municipal Science and Technology Project grant (Z161100000116050 and Z161100003216212) and Beijing Municipal Administration of Hospitals Clinical Technology Innovation Project grant (XMLX201701).

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Early Atherosclerosis in Rheumatoid Arthritis: A case Control Study

JMS SKIMS ◽

10.33883/jms.v15i2.144 ◽

2012 ◽

Vol 15 (2) ◽

pp. 106-110

Author(s):

Sonaullah Shah ◽

Nitin Gupta ◽

Feroze Shaheen ◽

Fayaz Ahmad Sofi ◽

Umar Hafeez ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Risk Factors ◽

Disease Activity ◽

Tertiary Care ◽

Developed Countries ◽

University Hospital ◽

Age Group ◽

Serum Triglycerides ◽

Accelerated Atherosclerosis ◽

Intergroup Comparison

BACKGROUND: Atherosclerosis remains the major cause of death and premature disability in developed countries. OBJECTIVES: To assess the prevalence of early (accelerated) atherosclerosis in Rheumatoid Arthritis (RA) patients in the absence of traditional risk factors and influence of various other parameters on it. METHODS: The study was carried at a tertiary care university hospital in northern India (Kashmir) in year 2008-2009. Thirty nine patients in the age group of 25- 55 years with RA fulfilling the American College of Rheumatology (ACR) Modified criteria 1987 and a purposive sample of twenty healthy volunteers that served as controls were enrolled to judge any difference in the studied parameters. Subjects with other risk factors for atherosclerosis were excluded from the study. Disease Activity Score (DAS-28) was used to measure the disease activity. B-mode ultrasonography was used to measure carotid artery intima media thickness (CIMT) in both the groups. RESULTS: RA patients presented with elevated CIMT in the age group of 41-50 years (p = 0.665) whereas volunteers had such tendency in the 5th decade of life (p = 0.550). Duration of disease greater than 5 years also positively influenced the development of increased CIMT in the patient group (p 0.64).Patients in the RA group had a higher erythrocyte sedimentation rate (ESR) and mean CIMT as compared to the controls(p = 0.000). RA patients had lower hemoglobin concentration when compared to age and sex matched controls. Intergroup comparison in patients with normal and increased CIMT showed that increased BMI, elevated triglyceride (TG) concentration and raised ESR influenced the development of CIMT which on binary logistic regression showed that TG (p = 0.043) and BMI (p = 0.053) had influence in progression of CIMT. CONCLUSION: Rheumatoid Arthritis patients have definite evidence of early (accelerated) atherosclerosis due to inflammation even in this ethnic population. BMI and serum triglycerides even in normal range have noteworthy influence in acceleration of atherosclerosis in them. B-mode ultrasonography is simple, non-invasive, and one of the sensitive methods to detect earlier atherosclerotic changes in them. JMS 2012;15(2):106-110

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Clinical Profile of Stroke Patients Attended in a Tertiary Care Hospital- Study of 219 cases

Bangladesh Journal of Neuroscience ◽

10.3329/bjn.v32i1.57408 ◽

2016 ◽

Vol 32 (1) ◽

pp. 16-20

Author(s):

Nayeem Anwar ◽

Md Rezaul Karim Khan ◽

Nawreen Binte Anwar ◽

Shamsun Nahar ◽

- Md Shahidullah

Keyword(s):

Risk Factors ◽

Recurrent Stroke ◽

Tertiary Care ◽

The Body ◽

Clinical Profile ◽

Care Hospital ◽

Age Group ◽

Stroke Patients ◽

Cross Sectional ◽

Study Results

Background: Stroke is serious pathology with a immense impact on the functional and vital prognosis. It is the leading cause of death worldwide. The objective of the study was to observe clinical profile of stroke patients and important risk factors. Methods: It was a cross-sectional descriptive study conducted in the department of Neurology, BangabandhuSheikh Mujib Medical Universiy(BSMMU), Shahbag, Dhaka from August 2014 to November2015. All patients above 18 years of age and both sexes attending the above mentioned department meeting all inclusion and exclusion criterias and confirmed CT/MRI scan of Brain were included in this study. Results: A total of 219 patients were studied. Maximum 93(42.5%) patients were in age group of 61-70 years followed by 51(23.3%) and 30(13.7%), in the age group of 51-60 years and 71-80 years respectively. Male 138(63%) were predominant than female 81(63%). 78(35.61%) patients had weakness in both sides of the body, 66(30.1%) had weakness in the left side and 36(16.4%) had weakness in the right side of the body. 190 (87.7) patients had ischemic stroke and 29(12.3%) had hemorrhagic stroke. Among risk factors dyslipidemia was in 185(84.5%) patients, hypertension, smoking habits, diabetes mellitus and ischemic heart disease were present in 165(75.3%), 120(54.8%), 105(47.9%) and 42 (19.2%) patients respectively. H/O recurrent stroke was present in 55(25%) cases. Conclusion: Stroke cases were male predominant where dyslipidaemia was the most common risk factor, most common type of stroke was ischemic, most common presentation was hemiplegia/monoplegia and commonest age of presentation was seventh decade. Bangladesh Journal of Neuroscience 2016; Vol. 32 (1): 16-20

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Frequency of Risk Factors Leading to Acute Respiratory Infections Among Children Under Two Year’s Age and their Gender and Age Wise Comparison

Journal of Gandhara Medical and Dental Science ◽

10.37762/jgmds.3-01.43 ◽

2016 ◽

Vol 3 (01) ◽

pp. 16-21

Author(s):

Nighat Musa ◽

Riaz Gul ◽

Yasir Mehmood ◽

Saira Afridi

Keyword(s):

Risk Factors ◽

Respiratory Infections ◽

Tertiary Care ◽

Study Data ◽

Acute Respiratory Infections ◽

Age Group ◽

Cross Sectional ◽

Female Children ◽

Sick Children ◽

Tract Infections

OBJECTIVETo determine the frequency of different risk factors leading to Acute Respiratory Infections among children under two yearsTo determine the most susceptible age group and to compare frequency of disease in both gendersMETHODOLOGYStudy design was cross sectional observational. Duration of the study was three months (September – November 2014. Study was conducted in two tertiary care hospitals of Peshawar namely Khyber Teaching hospital & Hayatabad Medical Complex. A total of 200 children under 2 years of age who were attending outpatient department of two tertiary hospitals of Peshawar were studied. After getting consent from parents of children, data was collected from parents. A semi structured questionnaire was used as study tool. Pilot study was conducted prior to the actual study to check the feasibility of questionnaire. Children with acute respiratory tract infections were included in the study while immune compromised and children with other serious systemic diseases were excluded from the study Data was presented in the form of tables and graphs.RESULTSFrequency of acute respiratory infections was common among males (65%) as compare to female children under two year of age. The most susceptible age group was found to be less than 06 months (46%), then is 7-12 months (33%). Environmental risk factors found to be involved in cases of ARI were poverty (73.5%), rural residency with poor cross ventilation in houses (poor or no cross ventilation 66%), no or partial immunization was 35% with malnutrition of sick children 76% may contribute to development of illness more quickly than other children. Illiteracy among mothers (78%) and 39% among fathersCONCLUSIONSARI is more common in infants less than 6 months of age and males are more affected as compared to female children. Poor socioeconomic status, Illiteracy, poor or no cross ventilation in houses, poor immunization status and malnutrition are the key risk factors.

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