scholarly journals Frequency of Risk Factors Leading to Acute Respiratory Infections Among Children Under Two Year’s Age and their Gender and Age Wise Comparison

2016 ◽  
Vol 3 (01) ◽  
pp. 16-21
Author(s):  
Nighat Musa ◽  
Riaz Gul ◽  
Yasir Mehmood ◽  
Saira Afridi

OBJECTIVETo determine the frequency of different risk factors leading to Acute Respiratory Infections among children under two yearsTo determine the most susceptible age group and to compare frequency of disease in both gendersMETHODOLOGYStudy design was cross sectional observational. Duration of the study was three months (September – November 2014. Study was conducted in two tertiary care hospitals of Peshawar namely Khyber Teaching hospital & Hayatabad Medical Complex. A total of 200 children under 2 years of age who were attending outpatient department of two tertiary hospitals of Peshawar were studied. After getting consent from parents of children, data was collected from parents. A semi structured questionnaire was used as study tool. Pilot study was conducted prior to the actual study to check the feasibility of questionnaire. Children with acute respiratory tract infections were included in the study while immune compromised and children with other serious systemic diseases were excluded from the study Data was presented in the form of tables and graphs.RESULTSFrequency of acute respiratory infections was common among males (65%) as compare to female children under two year of age. The most susceptible age group was found to be less than 06 months (46%), then is 7-12 months (33%). Environmental risk factors found to be involved in cases of ARI were poverty (73.5%), rural residency with poor cross ventilation in houses (poor or no cross ventilation 66%), no or partial immunization was 35% with malnutrition of sick children 76% may contribute to development of illness more quickly than other children. Illiteracy among mothers (78%) and 39% among fathersCONCLUSIONSARI is more common in infants less than 6 months of age and males are more affected as compared to female children. Poor socioeconomic status, Illiteracy, poor or no cross ventilation in houses, poor immunization status and malnutrition are the key risk factors.

Author(s):  
Alka C. Kaware ◽  
Nitin H. Kamble ◽  
S. K. Mangulikar

Background: Acute respiratory infections (ARI) is an important cause of mortality and morbidity in children. In India, it constitutes 15% of under five deaths. Various risk factors are responsible for ARI in children. Study of risk factors will help to reduce the high morbidity and mortality due to ARI. The objectives were to study risk factors responsible for acute respiratory infections in children and to find out case fatality rate &/ outcome of acute respiratory infections ARI in children.Methods: A hospital based cross sectional study was done in 2013-14 in a tertiary care centre to study the risk factors associated with ARI in children. All the pediatric patients between 0-12 years admitted in a tertiary care centre at Solapur were enrolled in the study.Results: Acute respiratory tract infections (ARI) were more common in 1-4 years age group i.e. 57.31% (196). It was more common in males i.e. 64.33% (220) than females i.e. 35.67% (122). ARI was more common in lower socio-economic classes i.e. class V (50.58%), class IV (22.52%); in patients whose mothers were illiterate 43.28% and who had history of parental smoking 84.21%. Maximum patients of ARI were having history of overcrowding 75.73%, inadequate cross-ventilation 81.87% and use of smoky chullah 78.65% in their home. Statistically significant association found between ARI cases and these socio-demographic factors. 46.78% (160) were incompletely immunized and 16.37% (56) were not immunized at all. Only 36.84% (126) were completely immunized for their age. Maximum cases of ARI (50.88%) occurred in winter season followed by rainy season (26.90%). Outcome showed that 91.52% (313) were cured, while 1.75% (6) patients died due to ARI.Conclusions: The present study has identified various socio-demographic, nutritional and environmental risk factors for ARI which can be prevented by effective health education and an appropriate initiative taken by the government.


2019 ◽  
Vol 11 (3) ◽  
pp. 38-45
Author(s):  
S. A. Khmilevskaya ◽  
N. I. Zryachkin ◽  
V. E. Mikhailova

The aim: to study the etiological structure of acute respiratory infections in children aged 3 to 12 hospitalized in the early stages of the disease in the department of respiratory infections of the children’s hospital, and to reveal the features of their clinical course and the timing of DNA / RNA elimination of respiratory viruses from nasal secretions, depending on the method of therapy. Materials and methods: 100 children with acute respiratory infections aged 3 to 12 years were monitored. The nasal secrets on the DNA / RNA of respiratory viruses were studied by PCR. Depending on the method of therapy, patients were divided into 2 groups: patients of group 1 (comparison) received basic treatment (without the use of antiviral drugs), in patients of the 2nd group (main), along with basal therapy, the drug was used umifenovir in a 5-day course at the ageappropriate dosage. Results: In the etiologic structure of ARVI in children from 3 to 12 years, the leading place was taken by rhinovirus, influenza and metapneumovirus infections (isolated – 18%, 19% and 20% respectively, in the form of a mixed infection – 11%). The main syndromic diagnosis at the height of the disease was rhinopharyngitis. Complications were observed in 42% of cases, as often as possible with flu – 53% of cases. Features of metapneumovirus infection in children of this age group were: predominance of non-severe forms of the disease in the form of acute fever with symptoms of rhinopharyngitis, as well as a small incidence of lower respiratory tract infections. The use of the drug umiphenovir in children with acute respiratory viral infections of various etiologies contributed to significantly faster elimination of viral DNA / RNA from the nasal secretion, which was accompanied by a ecrease in the duration of the main clinical and hematological symptoms of the disease, a decrease in the incidence of complications, and reduced the duration of stay in hospital. Conclusion: application of modern molecular genetic methods of diagnostics made it possible to identify the leading role of influenza, metapneumovirus and rhinovirus infections in the etiology of acute respiratory viral infection in patients aged 3 to 12 years, and to determine a number of clinical features characteristic of this age group. The results of the study testify to the effectiveness of umiphenovir in the treatment of children with acute respiratory viral infections of various etiologies and allow us to recommend this drug as an effective and safe etiotropic agent.


2021 ◽  
Author(s):  
Fasih Ali Ahmed ◽  
Omair Ahmed ◽  
Sameer Ahmad Khan ◽  
Naveera Khan ◽  
Sara Ahmed ◽  
...  

Abstract BackgroundDue to shrinking therapeutic options, infections due to Carbapenem-resistant Enterobacterales (CRE) are an urgent threat in healthcare systems. We compared the risk factors and outcomes of bacteremia secondary to CRE with bacteremia secondary to carbapenem susceptible Enterobacterales (CSE).MethodsWe conducted a retrospective cross-sectional study on patients admitted to a tertiary care hospital in Karachi, Pakistan between 2013 and 2016. Patients with CRE bacteremia were matched to those with CSE bacteremia while excluding those with polymicrobial cultures.ResultsA total of 131 patients were enrolled (65 CRE and 66 CSE) with the mean age of 51.8 years and 57.1 years in CRE and CSE groups respectively. Compared with CSE, CRE bacteremia was more likely to occur in patients with Diabetes Mellitus or those with a tracheostomy (P = 0.002 and 0.014, respectively). The most common source of CRE bacteremia was central line associated (24.6% of all cases) as opposed to urinary tract infections in those with CSE bacteremia (62.1% of all cases). Fewer patients with CRE bacteremia received appropriate antibiotics (72.3% vs. 81.8%). Mortality was significantly higher in the CRE group (41.5% vs. 12.1%, P = 0.001) even when adjusted for the severity of illness using the PITT-bacteremia score. Increased mortality was also associated with central venous catheterization in both groups. The median length of hospital stay was longer in patients with CRE (8 vs. 6 days, P = 0.021)ConclusionCRE bacteremia was associated with central lines and led to significantly higher mortality and length of stay.


2019 ◽  
Vol 31 (1) ◽  
pp. 13-17
Author(s):  
B Raju ◽  
A Rishab ◽  
K Vikram ◽  
T Vaibhav ◽  
T Sharat ◽  
...  

Background: Decrease in serum sodium concentration is frequent observation among hospitalised elderly patients. The common causes for hyponatremia are degenerative physiology, dehydration, medications and infections. Hence the present study was undertaken to know the extent of hyponatremia among elderly with Lower Respiratory Tract Infections. Objectives: The present study was undertaken to assess the prevalence of hyponatremia in lower respiratory tract infection among geriatric age group and to determine the association between severity of hyponatraemia and LRTI. Methods: This was hospital based cross sectional study carried out in the Department of General Medicine of a tertiary care teaching hospital situated in north Karnataka, India during November 2016 to May 2018. 100 elderly patients (age e” 60 years) with history of cough for more than four to five days, clinical findings and X-ray findings suggestive of LRTI, were selected for the study. Results: In the present study 59% comprised of male whereas females constituted 41%. The prevalence of hyponatraemia among elderly patients with LRTI was 45%. The most common cause of hyponatraemia was GI loss (vomiting) 53.33%, Euvolemic hyponatramia 51.11%. The mean age was 69.99±8.44 years. Most of the patients were aged between 61 to 70 years. .Hyponatraemia was not associated with sex, age and type of LRTI. Duration of hospital stay was significantly longer in patients with hyponatraemia compared to those who did not develop hyponatraemia. Conclusion: Hyponatraemia among elderly individuals with LRTI is higher as compared to other age group hence leading to prolonged duration of hospitalisation. Bangladesh J Medicine Jan 2020; 31(1) : 13-17


2016 ◽  
Vol 32 (1) ◽  
pp. 16-20
Author(s):  
Nayeem Anwar ◽  
Md Rezaul Karim Khan ◽  
Nawreen Binte Anwar ◽  
Shamsun Nahar ◽  
- Md Shahidullah

Background: Stroke is serious pathology with a immense impact on the functional and vital prognosis. It is the leading cause of death worldwide. The objective of the study was to observe clinical profile of stroke patients and important risk factors. Methods: It was a cross-sectional descriptive study conducted in the department of Neurology, BangabandhuSheikh Mujib Medical Universiy(BSMMU), Shahbag, Dhaka from August 2014 to November2015. All patients above 18 years of age and both sexes attending the above mentioned department meeting all inclusion and exclusion criterias and confirmed CT/MRI scan of Brain were included in this study. Results: A total of 219 patients were studied. Maximum 93(42.5%) patients were in age group of 61-70 years followed by 51(23.3%) and 30(13.7%), in the age group of 51-60 years and 71-80 years respectively. Male 138(63%) were predominant than female 81(63%). 78(35.61%) patients had weakness in both sides of the body, 66(30.1%) had weakness in the left side and 36(16.4%) had weakness in the right side of the body. 190 (87.7) patients had ischemic stroke and 29(12.3%) had hemorrhagic stroke. Among risk factors dyslipidemia was in 185(84.5%) patients, hypertension, smoking habits, diabetes mellitus and ischemic heart disease were present in 165(75.3%), 120(54.8%), 105(47.9%) and 42 (19.2%) patients respectively. H/O recurrent stroke was present in 55(25%) cases. Conclusion: Stroke cases were male predominant where dyslipidaemia was the most common risk factor, most common type of stroke was ischemic, most common presentation was hemiplegia/monoplegia and commonest age of presentation was seventh decade. Bangladesh Journal of Neuroscience 2016; Vol. 32 (1): 16-20


2017 ◽  
Vol 5 (2) ◽  
Author(s):  
Budi Kristanto ◽  
Ambrosius Setya Widri Hanggara

Background : deaths due to ARI disease in infants reaching 12.4 million in toddlers 0-5year age group every year worldwide, two thirds are babies, that is 0-1 years old and80.3% of deaths occur in developing countries (Kemenkes , 2010). The prevalence ofARI occurrence in Indonesia is 25.0% (Riskesdas, 2013: 23). Smoking habits of parentsin the home make toddlers as passive smokers are always exposed to cigarette smoke.Research purposes : to determine the relationship between exposure to secondhandsmoke with the incidence of acute respiratory infections in infants.Subject : toddlers who checked at Puskesmas Baturetno 1 in February-March 2017 werediagnosed with acute respiratory infection.Methods : this research use correlation research design with cross sectional method. Thepopulation is all parents of children under five who checked their children to Baturetno IPuskesmas in February and March with an acute respiratory infection diagnosis, a total of20 respondents. Control group of children who did not experience acute respiratory tractinfection of 20. Researchers used questionnaire tools. Data obtained then tabulated andanalyzed using SPSS 16 for Windows.Results : 15 children (75%) were exposed to cigarette smoke and 5 children (25%) werenot exposed to cigarette smoke. There was an association between ARI occurrence andexposure of cigarette smoke to under-five children at Puskesmas Baturetno I with p:0.011 <α: 0.05Conclusion : There is a correlation between ARI occurrence and exposure of tobaccosmoke in infants at Puskesmas Baturetno I.Keywords: smoking, acute respiratory infections, less than five years


2020 ◽  
Author(s):  
Tefera Manaye ◽  
Pawlos Wasihun Asnake ◽  
Ashebr Abraha ◽  
Tsegaw Fentie

Abstract Background: Bovine respiratory disease (BRD) is considered as the major cause of severe respiratory tract infections in calves. Pasteurellosis is a multifactorial respiratory disease, which mainly affect calves within four weeks of weaning. A cross-sectional study was conducted from October 2017 to April 2018 in and around Gondar town, Amhara Regional State, North West of Ethiopia. The aim of the study was to isolate Mannheimia and Pasteurella species from calves up to six months old, and to assess the associated risk factors with the occurrence of respiratory disease. Sex, age (< 16 weeks and > 16 weeks), body condition status (poor, medium, good), breed (local and cross breed), livelihood (mixed crop and urban), farming systems (semi intensive and intensive), herd size (small medium, and large), maternity pens (present or absent), and method of colostrum feedings (hand bucket and suckling) were the examined risk factors.Results: A total of 84 nasopharyngeal swab samples were collected from calves with any signs of illness related to pasteurellosis. The overall isolation rate of the respiratory pathogens was 64/84 (76.2%) (95% CI=65.7-84.8), with 46.4% of Mannheimia haemolytica and 28.8% Pasteurella multocida isolates. The distribution of pathogens was statistically higher (P< 0.001) in calves with respiratory problems (93.6%; 95% CI= 82.5-98.7) compared to those with no symptoms of respiratory illness (54.1%; 95% CI= 36.9-70.5). Among the examined risk factors age, sex, breed, farming system were found to be potential risk factors and significantly associated with Pasteurella infection of calves (p<0.05). The higher isolation rate of Mannheimia haemolytica indicated that it is the major cause of respiratory disease in the study area.Conclusion: The present finding revealed that pasteurellosis is one of the major diseases of calves in the study area in which M. haemolytica and P. multocida were found to be commonly involved in respiratory infections. Improved farm management including timely feeding of colostrum, appropriate hygiene of the calf house and training of farmers is recommended to prevent and control of respiratory diseases in the study area.


2020 ◽  
Vol 9 (1) ◽  
pp. 382
Author(s):  
Marhaeni Hasan ◽  
Fera The

Acute Respiratory Infection (ARI) continues to be the leading cause of death in infants and children under the age of five throughout the world. ARI is responsible for the deaths of around 3.9 million children worldwide each year. It was reported that around 40% of total deaths from ARI around the world occurred in Bangladesh, India, Indonesia, and Nepal. The results of the 2013 Basic Health Research (Riskesdas) report showed that the prevalence of ARI in Indonesia is still quite high at 25%. The highest prevalence occurred in infants (25.8%) and infants (22%). This study aims to determine the factors that influence the incidence of acute respiratory infections (ARI) in children 0-5 years on Moti Island. This study uses an observational study using a cross-sectional approach. The samples used were 100 people with an age range of 0-5 years. The data used in the form of a questionnaire. The results showed that education occupying the highest percentage was elementary school (SD) graduates, 38%, while the percentage according to employment was as follows, the highest percentage was housewives (83%), the majority of toddlers born weighing over 2500 grams (89%), complete immunization 81%, exclusive breastfeeding has also reached 76%, 81% of these toddlers live in families who have smoking habits, 79% of respondents still use fuel, 80% of parents whose environment around the house is dusty. The conclusion that can be drawn is the risk factors that most influence the incidence of ARI in infants on Moti Island are environmental factors, namely the level of occupancy density, dusty house conditions, the use of firewood as fuel for cooking, and smoking habits of family members in the house.


2020 ◽  
Author(s):  
Johannes Schetelig ◽  
Henning Baldauf ◽  
Sarah Wendler ◽  
Falk Heidenreich ◽  
Ruben Real ◽  
...  

AbstractBackgroundWith increasing rates of SARS-CoV-2 infections and the intention to avoid a lock-down, the risks for the working population are of great interest. No large studies have been conducted which allow risk assessment for this population.MethodsDKMS is a non-profit donor center for stem cell donation and reaches out to registered volunteers between 18 and 61 years of age. To identify risk factors for severe COVID-19 courses in this population we performed a cross-sectional study. Self-reported data on oro- or nasopharyngeal swabs, risk factors, symptoms and treatment were collected with a health questionnaire and linked to existing genetic data. We fitted multivariable logistic regression models for the risk of contracting SARS-CoV-2, risk of severe respiratory infection and risk of hospitalization.FindingsOf 4,440,895 contacted volunteers 924,660 (20.8%) participated in the study. Among 157,544 participants tested, 7,948 reported SARS-CoV-2 detection. Of those, 947 participants (11.9%) reported an asymptomatic course, 5,014 (63.1%) mild/moderate respiratory infections, and 1,987 (25%) severe respiratory tract infections. In total, 286 participants (3.6%) were hospitalized for respiratory tract infections. The risk of hospitalization in comparison to a 20-year old person of normal weight was 2.1-fold higher (95%-CI, 1.2-3.69, p=0.01) for a person of same age with a BMI between 35-40 kg/m2, it was 5.33-fold higher (95%-CI, 2.92-9.70, p<0.001) for a 55-year old person with normal weight and 11.2-fold higher (95%-CI, 10.1-14.6, p<0.001) for a 55-year old person with a BMI between 35-40 kg/m2. Blood group A was associated with a 1.15-fold higher risk for contracting SARS-CoV-2 (95%-CI 1.08-1.22, p<0.001) than blood group O but did not impact COVID-19 severity.InterpretationIn this relatively healthy population, the risk for hospitalizations due to SARS-CoV-2 infections was moderate. Age and BMI were major risk factors. These data may help to tailor risk-stratified preventive measures.FundingDKMS initiated and conducted this study. The Federal Ministry of Education and Research (BMBF) supported the study by a research grant (COVID-19 call (202), reference number 01KI20177).


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