Prevalence and Age-Related Association of Abnormal Endocrine Changes among Women with Menstrual Disorder

Faizah Mughal ◽  
Ashok Kumar ◽  
Jai Dev Maheshwari ◽  
Ali Nawaz Bijarani ◽  
Tayyaba Kazmi ◽  

Background: The menstrual cycle describes the healthy reproductive system of the women which is controlled by different hormones. Aim: The goal of the study is to evaluate the prevalence of irregular menstruation in different endocrine changes and to identify their association with the age of women in reproductive life. Methodology: It was a cross-sectional study conducted on women attending the gynecological clinic of Karachi from March 2019 to June 2019. Of the 165 women with different hormonal changes 100 presented with menstrual cycle abnormality. Results: Among the women with menstrual irregularities 51% women presented with insulin resistance, 23% with hyperandrogenism, 19% with hypothyroidism and 7% hyperprolactinemia. Age-related association was observed in menstrual irregularities women with insulin resistant and hyperandrogenism. Conclusion: Menstrual cycle is a physiological process, any irregularities in cycle can be caused by  even  minimal  hormonal  imbalance.  As  a  result,  it  is  critical  to  address  endocrine abnormalities in order to improve women's reproductive health.

A. Shantha ◽  
Roselin V. ◽  
Srisanthanakrishnan V.

Background: Medical students are at high risk for developing menstrual irregularities due to their lifestyle, food pattern and exercise habits. Also, majority of the menstrual disorders are preventable by changing better lifestyle, early diagnosis and treatment. Hence this study was conducted with the objective of addressing the menstrual disorders and associated problems among the medical students.Methods: The cross-sectional study was conducted by the department of obstetrics and gynaecology, at Sri Muthukumaran Medical College Hospital and Research Institute, among the first, second- and third-year female students who are doing their MBBS course in the same institute, during the month of December 2019. A total of hundred students were included in the study. Data was collected using a proforma and analysis was done using Statistical Package for Social Sciences (SPSS) version 17.Results: Menstrual cycle periodicity was irregular among 17% of participants. Dysmenorrhoea, mid cycle pain, heavy menstrual bleeding was noted among 27%, 19% and 11% respectively. Also 10% of students reported sickness absenteeism due to menstrual disorders.Conclusions: Adolescent students should be educated on the importance of physical and mental health in terms of healthy food habits and regular physical exercise to overcome the menstrual disorders and to enjoy healthy reproductive period.

2008 ◽  
Vol 179 (4S) ◽  
pp. 300-301
Ernani L Rhoden ◽  
Charles E Riedner ◽  
Eduardo P Ribeiro ◽  
Graziela Halmenschlager

Emotion ◽  
2009 ◽  
Vol 9 (5) ◽  
pp. 619-630 ◽  
Aire Mill ◽  
Jüri Allik ◽  
Anu Realo ◽  
Raivo Valk

2012 ◽  
Vol 19 (4) ◽  
pp. 287-298 ◽  
Isabel Pavão Martins ◽  
Carolina Maruta ◽  
Cláudia Silva ◽  
Pedro Rodrigues ◽  
Catarina Chester ◽  

2006 ◽  
Vol 72 (2) ◽  
pp. 1027-1033 ◽  
Susanne Mueller ◽  
Katiana Saunier ◽  
Christiana Hanisch ◽  
Elisabeth Norin ◽  
Livia Alm ◽  

ABSTRACT A cross-sectional study on intestinal microbiota composition was performed on 230 healthy subjects at four European locations in France, Germany, Italy, and Sweden. The study participants were assigned to two age groups: 20 to 50 years (mean age, 35 years; n = 85) and >60 years (mean age, 75 years; n = 145). A set of 14 group- and species-specific 16S rRNA-targeted oligonucleotide probes was applied to the analysis of fecal samples by fluorescence in situ hybridization coupled with flow cytometry. Marked country-age interactions were observed for the German and Italian study groups. These interactions were inverse for the predominant bacterial groups Eubacterium rectale-Clostridium coccoides and Bacteroides-Prevotella. Differences between European populations were observed for the Bifidobacterium group only. Proportions of bifidobacteria were two- to threefold higher in the Italian study population than in any other study group, and this effect was independent of age. Higher proportions of enterobacteria were found in all elderly volunteers independent of the location. Gender effects were observed for the Bacteroides-Prevotella group, with higher levels in males than in females. In summary, age-related differences in the microbiota makeup were detected but differed between the study populations from the four countries, each showing a characteristic colonization pattern.

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e035805
Zhuoting Zhu ◽  
Huan Liao ◽  
Sen Liu ◽  
Jian Zhang ◽  
Yifan Chen ◽  

ObjectiveTo explore the association between age-related macular degeneration (AMD) and arthritis in a representative sample of the US population.DesignPopulation-based, cross-sectional study.SettingThe National Health and Nutrition Examination Survey (NHANES) 2005–2008.ParticipantsA total of 4813 participants aged 40 years and older with available information on AMD and arthritis in the 2005–2008 NHANES.MethodsThe status and types of arthritis were obtained from questionnaires. Non-mydriatic fundus photographs were collected. The types of AMD were assessed using the modified Wisconsin Age-Related Maculopathy Grading Classification Scheme. The association between arthritis and AMD was evaluated using logistic regression models.ResultsAfter adjusting for covariates, participants with any or early AMD had significantly lower odds of having any type of arthritis (any AMD: OR=0.56, 95% CI: 0.36–0.86; early AMD: OR=0.55, 95% CI: 0.34–0.88) or osteoarthritis (OA) (any AMD: OR=0.43, 95% CI: 0.26–0.71; early AMD: OR=0.44, 95% CI: 0.25–0.76) compared with those without AMD. When considering AMD as the outcome, significant negative associations were also found between any arthritis or OA and any (any arthritis: OR=0.64, 95% CI: 0.43–0.94; OA: OR=0.52, 95% CI: 0.33–0.82) or early AMD (any arthritis: OR=0.61, 95% CI: 0.40–0.93; OA: OR=0.51, 95% CI: 0.31–0.86) in the multivariable logistic models. There was no significant association between different types of arthritis and late AMD.ConclusionsPeople with arthritis, especially those with OA, were less likely to have AMD compared with those without arthritis and vice versa. Further studies are needed to confirm this potential protective effect of arthritis and/or arthritis treatment on AMD and to explore the underlying mechanisms.

Raphaele Tsao ◽  
Cecile Kindelberger ◽  
Benedicte Fréminville ◽  
Renaud Touraine ◽  
Gerald Bussy

Abstract The aim of this cross-sectional study was to analyze the typical aging process in adults with Down syndrome, focusing on its variability. The sample comprised 120 adults with Down syndrome who were free of dementia. Ages ranged from 20 to 69 years. Each participant was assessed on cognitive functioning and social adaptation, and was checked for the presence of psychopathological disorders. Results revealed an age-related deterioration in both cognitive and social adaptation skills, the extent of this decline depending on the dimension under scrutiny, and interindividual variability in aging profiles.

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e85263 ◽  
Dana S. Forcey ◽  
Jane S. Hocking ◽  
Sepehr N. Tabrizi ◽  
Catriona S. Bradshaw ◽  
Marcus Y. Chen ◽  

Etienne Belinga ◽  
Isidore Tompeen ◽  
Claude Cyrille Noa Ndoua ◽  
Junie Metogo Ntsama ◽  
Sandrine Mendibi ◽  

Background: Uterine synechiae refers to a total or partial union of the inner walls of the uterus resulting from endometrial trauma. It is a cause of reproductive failure. Until now, synechia was not optimally treated and has remained understudied in Cameroon. Objective of present study was to Evaluate the diagnostic, therapeutic and prognostic aspects of uterine synechiae treated by hysteroscopy.Methods: We conducted a descriptive cross-sectional study with an analytical component from January 1st 2015 to July 31st 2017 at Yaounde. All patients diagnosed with uterine synechiae and treated with hysteroscopy were our sample. Sampling was consecutive. The chi-square test was used for the comparison of qualitative variables and Fisher's test for ANOVA variance analysis. The comparison of the averages was made by the Student's test. P-value less than 0.05 was considered as statistically significant.Results: Hysteroscopies were indicated for uterine synechiae in 14.50%. Nulliparous were 56.67%. A history of curettage/aspiration was present in 66.66%. All of the patients had a form of infertility and 83.33% had menstrual disorders. Hysterosalpingography showed a better sensitivity (88%). After hysteroscopic treatment, 63.30% had a complete anatomical restitution. There is a significant correlation between the stage of severity of synechia and anatomical restitution (p=0.008; Spearman correlation coefficient=-0.477).Conclusions: Uterine synechiae represent one-sixth of all indications for hysteroscopy and present clinically as menstrual disorder associated with infertility. A past history of uterine curettage is common. Hysterosalpingography has a better preoperative diagnostic sensitivity. Hysteroscopy allows optimal treatment.

Sign in / Sign up

Export Citation Format

Share Document