scholarly journals Predictor of Severity of Lung Injury and Oxygen Saturation in COVID- 19 Patients

2021 ◽  
pp. 107-114
Author(s):  
Fahimeh Shahjooie ◽  
Sadrollah Mahmudi ◽  
Somayeh Mohammadi ◽  
Hassan Goodarzi ◽  
Mehrdad Farajy ◽  
...  
Keyword(s):  
Lung Injury ◽  
Oxygen Saturation ◽  
Significant Relationship ◽  
Wide Spectrum ◽  
Severe Disease ◽  
Cross Sectional Study ◽  
Shortness Of Breath ◽  
Blood Oxygen Saturation ◽  
Cross Sectional ◽  
Early Management

Introduction: Wide spectrum of clinical features of COVID-19 was seen from mild to severe. This is very important to determine the severity of disease, early management of severe disorder may increase the chance of survival. Methods: This cross sectional study perform on 150 patients with mean age of 53 years that refer to from 21 February to 19 April 2020. Result: The most comorbidity disease HTN, DM and IHD with prevalence of 26.2%, 20%, 11.3% which had higher severity of lung disease. There was a significant relationship between age, lymphopenia, CRP, IHD, DM, shortness of breath and body pain with the severity of lung injury, shortness of breath had higher severity of lung injury but myalgia had a lower severity rather than the others.  level of the LDH was associated with chest CT scan score and so severe disease Further results showed that the mean±SD of LDH in 3 CT group were 576.30±214.82, 641.89± 277.07, 919.92± 382.14 in CT score less than 20, 20-50 and more than 50 respectively (P=0.002). According this study there was significant relationship between age, BMI, CRP, shortness of breath and fever with blood oxygen saturation. Further results showed that the correlation between LDH and oxygen saturation was r=-0.31 (p=0.002)

scholarly journals Profile of COVID-19 patients in COVID dedicated tertiary care centre in Himachal Pradesh: a prospective observational cross sectional study

2021 ◽  
Vol 9 (11) ◽  
pp. 3284
Author(s):  
Roshan Lal ◽  
Rajesh K. Bhawani ◽  
Santosh K. Dheer ◽  
Nitesh Kumar ◽  
Soni Kumar
Keyword(s):  
Senior Citizens ◽  
Severe Disease ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Shortness Of Breath ◽  
Tertiary Care Centre ◽  
Specific Therapy ◽  
Cross Sectional ◽  
Poor Outcome ◽  
Initial Stage

Background: COVID-19 pandemic originated in China in December 2019 and fumed in whole world over few months. Millions of deaths have occurred worldwide till now because of this pandemic. Causative agent was identified as severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) causing viral pneumonia and serious manifestations were seen in association with increased age and comorbidies.Methods: This study was planned in very initial stage of pandemic in our country to study the profile of COVID-19 patients. This study was conducted over a period of six months from April 2020 to September 2020 at SLBSGMCH, Mandi at Nerchowk.Results: 202 patients were enrolled for this study with mean age of presentation 48 years, 61 were females, 147 (72%) were senior citizens, most patients were from district Mandi and most common symptoms were fever (58%), cough (46%), shortness of breath (35%) and associated commonest comorbidities were hypertension (HTN) (29%) and diabetes (23%). Median neutrophil to lymphocyte ratio (NLR) was higher (5.47) in moderate to severe disease and associated with poor outcome. All the 11 patients who were put on support of ventilator, succumbed to death.Conclusions: Most common symptoms were fever, cough, shortness of breath and most common comorbidty was HTN. Comorbidity, increased age and higher NLR were risk factors for severity and poor outcome. More research is needed to save mankind from this pandemic as still no specific therapy is available against this virus.

Prevalence of COVID-19-like Symptoms among People Living with HIV, and Using Antiretroviral Therapy for Prevention and Treatment

2020 ◽  
Vol 18 (5) ◽  
pp. 373-380 ◽  
Author(s):  
SeyedAhmad SeyedAlinaghi ◽  
Maryam Ghadimi ◽  
Mahboubeh Hajiabdolbaghi ◽  
Mehrnaz Rasoolinejad ◽  
Ladan Abbasian ◽  
...  
Keyword(s):  
Respiratory Symptoms ◽  
Antiretroviral Treatment ◽  
Clinical Symptoms ◽  
Cross Sectional Study ◽  
People Living With Hiv ◽  
Shortness Of Breath ◽  
Sectional Study ◽  
Limited Data ◽  
Cross Sectional ◽  
Living With Hiv

Background: COVID-19 has spread globally with remarkable speed, and currently, there is limited data available exploring any aspect of the intersection between HIV and SARSCoV- 2 co-infection. Objective: To estimate the prevalence of clinical symptoms associated with COVID-19 among people living with HIV (PLWH) in Tehran, Iran. Design: Cross-sectional study. Methods: A total of 200 PLWH were recruited through the positive club via sampling, and completed the symptom-based questionnaire for COVID-19, which was delivered by trained peers. Results: Of 200 participants, respiratory symptoms, including cough, sputum, and shortness of breath, were the most prevalent among participants, but only one person developed symptoms collectively suggested COVID-19 and sought treatments. Conclusions: It appears that existing infection with HIV or receiving antiretroviral treatment (ART) might reduce the susceptibility to the infection with SARS-CoV-2 or decrease the severity of the infection acquired. Further research is needed to understand causal mechanisms.

scholarly journals Illness severity and risk of mental morbidities among patients recovering from COVID-19: a cross-sectional study in the Icelandic population

BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e049967
Author(s):  
Karen Sól Saevarsdóttir ◽  
Hildur Ýr Hilmarsdóttir ◽  
Ingibjörg Magnúsdóttir ◽  
Arna Hauksdóttir ◽  
Edda Bjork Thordardottir ◽  
...  
Keyword(s):  
Severe Disease ◽  
Symptom Burden ◽  
Cross Sectional Study ◽  
Illness Severity ◽  
University Education ◽  
Adjusted Relative Risk ◽  
Sectional Study ◽  
Cross Sectional ◽  
Symptoms Of Depression ◽  
Increased Risk

ObjectiveTo test if patients recovering from COVID-19 are at increased risk of mental morbidities and to what extent such risk is exacerbated by illness severity.DesignPopulation-based cross-sectional study.SettingIceland.ParticipantsA total of 22 861 individuals were recruited through invitations to existing nationwide cohorts and a social media campaign from 24 April to 22 July 2020, of which 373 were patients recovering from COVID-19.Main outcome measuresSymptoms of depression (Patient Health Questionnaire), anxiety (General Anxiety Disorder Scale) and posttraumatic stress disorder (PTSD; modified Primary Care PTSD Screen for DSM-5) above screening thresholds. Adjusting for multiple covariates and comorbidities, multivariable Poisson regression was used to assess the association between COVID-19 severity and mental morbidities.ResultsCompared with individuals without a diagnosis of COVID-19, patients recovering from COVID-19 had increased risk of depression (22.1% vs 16.2%; adjusted relative risk (aRR) 1.48, 95% CI 1.20 to 1.82) and PTSD (19.5% vs 15.6%; aRR 1.38, 95% CI 1.09 to 1.75) but not anxiety (13.1% vs 11.3%; aRR 1.24, 95% CI 0.93 to 1.64). Elevated relative risks were limited to patients recovering from COVID-19 that were 40 years or older and were particularly high among individuals with university education. Among patients recovering from COVID-19, symptoms of depression were particularly common among those in the highest, compared with the lowest tertile of influenza-like symptom burden (47.1% vs 5.8%; aRR 6.42, 95% CI 2.77 to 14.87), among patients confined to bed for 7 days or longer compared with those never confined to bed (33.3% vs 10.9%; aRR 3.67, 95% CI 1.97 to 6.86) and among patients hospitalised for COVID-19 compared with those never admitted to hospital (48.1% vs 19.9%; aRR 2.72, 95% CI 1.67 to 4.44).ConclusionsSevere disease course is associated with increased risk of depression and PTSD among patients recovering from COVID-19.

scholarly journals Management of oxygen saturation monitoring in preterm newborns in the NICU: the Italian picture

2021 ◽  
Vol 47 (1) ◽  
Author(s):  
Serafina Perrone ◽  
◽  
Maurizio Giordano ◽  
Giuseppe De Bernardo ◽  
Paola Lugani ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Healthcare Professionals ◽  
Cross Sectional Study ◽  
Standard Operating Procedures ◽  
Specific Training ◽  
Related Factors ◽  
Cross Sectional ◽  
Survey Form ◽  
Standard Operating ◽  
Oxygen Monitoring

Abstract Background Although many studies emphasize the importance of using oxygen saturation (SpO2) targets in the NICUs, there is a wide variability in used saturation ranges among centers. Primary aim was to draw a representative picture on how the management of oxygen monitoring is performed in the Italian NICUs. Second aim was to identify healthcare-professionals related factors associated with oxygen targeting in the preterm population. Methods Cross-sectional study with data collection via an electronic survey form. A questionnaire containing pre-piloted and open questions on monitoring and management of the SpO2 was administered to neonatologists across the network of the Italian Society of Neonatology. The questions focused on: the infrastructure, specific training, healthcare professionals and patients-related factors. The results of the survey were anonymously collected, summarized and analyzed. Results Out of 378 questionnaires, 93 were correctly filled. Thirty-six different SpO2 ranges were observed. Centers using written standard operating procedures on oxygen management and SpO2 monitoring maintained a correct average range of SpO2 90–95%, avoided hyperoxia and reconsidered saturation targets in relation to comorbidities. 39.8% of responders disabled alarms during neonatal care. One center used biomarkers for complete monitoring of neonatal oxygenation status. Conclusions There is considerable variation in SpO2 targets for preterm infants in the Italian NICUs. Standard operating procedures and specific training for health care personnel are the main factors playing a role for the correct maintenance of the recommended oxygen targets in preterms.

scholarly journals PROFILE OF PATIENTS RECEIVING TOTAL KNEE ARTHROPLASTY: A CROSS-SECTIONAL STUDY

2017 ◽  
Vol 25 (5) ◽  
pp. 202-205 ◽  
Author(s):  
MARCELO JOSÉ CORTEZ BEZERRA ◽  
IGOR MAGALHÃES BARBOSA ◽  
THALES GONÇALVES DE SOUSA ◽  
LARISSA MEIRELES FERNANDES ◽  
DIEGO LEONARDO MENEZES MAIA ◽  
...  
Keyword(s):  
Medical Records ◽  
Severe Disease ◽  
Functional Limitation ◽  
Cross Sectional Study ◽  
Level Of Evidence ◽  
Cross Sectional ◽  
Lequesne Index ◽  
Total Knee ◽  
Epidemiological Profile

ABSTRACT Objective: To describe the epidemiological profile, presented deformities, associated comorbidities, and impact on quality of life in patients with knee osteoarthritis. This study was conducted in a philanthropic hospital in Fortaleza from 2014 to 2015. Methods: Data were collected from medical records, epidemiological forms, and by applying the Lequesne index questionnaire, which contains several questions related to pain, discomfort and functional limitation to assess the severity of symptoms. Results: Females were more prevalent (76.7%), as were patients over 65 years of age (61.6%) and non-whites (81.6%). As for comorbidities, 83.3% had hypertension and 31.7% had diabetes. Of the total, 76.5% cases were genu varum, and 23.5% genu valgum. According to the Lequesne index findings, 61.6% cases were “extremely severe,” and women had higher scores. Conclusion: Females were more prevalent and whites were less prevalent. The most frequent comorbidity was hypertension. Female and elderly patients have more severe disease according to Lequesne index score, and these findings were statistically significant. Level of Evidence II, Prospective Study.

scholarly journals Nail Involvement in Patients with Psoriatic Arthritis in Northern Iran

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
O. Zargari ◽  
E. Kazemnezhad Leyli ◽  
S. Z. Azimi
Keyword(s):  
Psoriatic Arthritis ◽  
Severe Disease ◽  
Cross Sectional Study ◽  
Joint Involvement ◽  
Sectional Study ◽  
Northern Iran ◽  
Cross Sectional ◽  
The Relationship ◽  
Nail Involvement

Background. Psoriatic arthritis (PsA) results in an increased burden of psoriasis and impairs both quality of life and an individual’s functional capacity. The relationship between nail involvement and PsA in psoriasis is not fully characterized. Aim. To evaluate the frequency and characteristics of nail involvement in psoriatic patients and to assess the relationship with joint involvement. Methods. A total of 197 patients with moderate-to-severe psoriasis were consecutively invited to participate in this cross-sectional study. The patients are divided into two groups: those with and those without psoriatic arthritis. Results. 69.5% of psoriatic (137 out of 197) patients had nail involvement. The most common nail abnormality was onycholysis, followed by pitting and oil droplet changes. Nail involvement was more common in patients with psoriatic arthritis (82.1% versus 57.8%, p=0.001). Conclusion. Nail involvement is commonly associated with PsA. Onycholysis, splinter hemorrhage, and oil drop were significantly more common in the PsA group as opposed to patients with just skin findings. In general, psoriatic patients with arthritis had more severe disease.

scholarly journals Autonomic modulation at rest and in response to postural change in adolescents with Duchenne muscular dystrophy: a cross-sectional study

2021 ◽  
Vol 79 (9) ◽  
pp. 766-773
Author(s):  
Mariana Viana Rodrigues ◽  
Mileide Cristina Stoco-Oliveira ◽  
Talita Dias da Silva ◽  
Celso Ferreira ◽  
Heloisa Balotari Valente ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Oxygen Saturation ◽  
Cross Sectional Study ◽  
Control Group ◽  
Autonomic Modulation ◽  
Postural Change ◽  
Cross Sectional

ABSTRACT Background: Analysis of autonomic modulation after postural change may inform the prognosis and guide treatment in different populations. However, this has been insufficiently explored among adolescents with Duchenne muscular dystrophy (DMD). Objective: To investigate autonomic modulation at rest and in response to an active sitting test (AST) among adolescents with DMD. Methods: Fifty-nine adolescents were included in the study and divided into two groups: 1) DMD group: adolescents diagnosed with DMD; 2) control group (CG): healthy adolescents. Participants’ weight and height were assessed. Lower limb function, motor limitations and functional abilities of the participants in the DMD group were classified using the Vignos scale, Egen classification and motor function measurement, respectively. The following variables were assessed before, during and after AST: systolic blood pressure (SBP), diastolic blood pressure (DBP), respiratory rate (f), oxygen saturation and heart rate (HR). To analyze the autonomic modulation, the HR was recorded beat-by-beat. Heart rate variability (HRV) indices were calculated in the time and frequency domains. Results: Differences in relation to groups were observed for all HRV indices, except LF/HF, oxygen saturation, HR and f (p < 0.05). Differences in relation to time and the interaction effect between group and time were observed for RMSSD, SD1, SD2, SD1/SD2, LFms2 and LFnu, HFun, SBP and DBP (p < 0.05). Differences in relation to time were also observed for the indice SDNN, FC and f (p < 0.05). Conclusions: Performing the AST promoted reduced autonomic modulation and increased SBP, DBP and HR in adolescents with DMD.

scholarly journals Moral distress among nurses working in Covid-19 wards: a cross-sectional study in 2021

2021 ◽  
Author(s):  
Mina Pooresmaeil ◽  
Masoumeh Aghamohammadi
Keyword(s):  
Significant Relationship ◽  
Work Experience ◽  
Moral Distress ◽  
Pearson Correlation ◽  
Cross Sectional Study ◽  
Moderate Level ◽  
Related Factors ◽  
Cross Sectional ◽  
Experienced Nurses ◽  
Distress Scale

Abstract Background Covid-19 is an emerging disease, which has confronted nurses with new moral distress. This study aims to determine the moral distress and its related factors among nurses working in the covid-19 wards of Ardabil city in Iran. Methods This cross-sectional descriptive study evaluated 159 nurses working in the covid-19 wards of Imam Khomeini hospital -as the only hospitalization center for the patients with covid-19 in Ardabil, 2021. The instruments used included a personal-occupational information form and Corley's moral distress scale. Data analysis was performed using descriptive and inferential statistics (Pearson correlation coefficient, independent t-test and one-way analysis of variance) in SPSS v22. Results The mean and standard deviation of the frequency and intensity of the nurses' moral distress were estimated 52.28 ± 5.24 and 51.54 ± 5.86, respectively, which indicated the moderate level of moral distress in the both dimensions. The item "I hesitate to tell the patient or the patient's family about his condition and treatment" (4.74 ± 0.75) showed the most moral distress based on the intensity and the phrase "too much work reduces the quality of my work” (4.81 ± 0.55) caused the most moral distress in the frequency dimension. The results indicated a significant relationship between the intensity and frequency of moral distress with the type of nurses' employment (P < 0.05). Moreover, a significant relationship was observed between the nurses’ position and the frequency (P = 0.04), and the nurses’ work experience and the intensity of moral distress (P = 0.02). Conclusions It seems that providing the necessary training for how to deal with the moral distress in new waves of the disease and using the experiences of the experienced nurses in this field are essential due to observing the moderate level of moral distress among nurses working in covid-19 wards.

scholarly journals Prevalence and Factors Related to Self-Medication for COVID-19 Prevention in the Elderly

Salmand ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. 112-127
Author(s):  
Narjes Heshmatifar ◽  
◽  
Arezoo Davarinia Motlagh Quchan ◽  
Zohreh Mohammadzadeh Tabrizi ◽  
Leila Moayed ◽  
...  
Keyword(s):  
Significant Relationship ◽  
Insurance Coverage ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Emotional Reactions ◽  
The Self ◽  
Self Medication ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Major Factors

Objectives: The Coronavirus Disease 2019 (COVID-19) crisis and health outcomes are among the major human social events of the 21st century. The unknown nature of the disease and the fear of contagion have caused emotional reactions, including the self-consumption of drugs in the elderly. Therefore, this study investigated factors affecting the self-consumption of drugs for COVID-19 prevention in the elderly. Methods & Materials: This descriptive and cross-sectional study was performed on 342 elderly in Sabzevar City, Iran, in 2020. The research units were selected as clusters from 16 health centers. The necessary data were collected by an online self-medication questionnaire. Data analysis was performed in SPSS. Results: The Mean±SD age of the study participants was 66.2±5.67 years. The frequency of self-medication to prevent COVID-19 was 190(55.5%); analgesics, vitamins, anti-cold, and antibiotics were the most common drugs used. The major factors associated with self-medication in the COVID-19 pandemic were disease prevention, home quarantine, financial problems, experiencing previous self-medication, and others’ advice. There was a significant relationship between self-medication and education and insurance coverage. No significant relationship was observed between gender, occupation, and marital status, and self-medication. Conclusion: Self-Medication in the COVID-19 epidemic is notable as a crisis threatening the elderly’s health. Controlling and monitoring how the drug is used is among the requirements for protection and health promotion in the elderly.

scholarly journals HUBUNGAN PEMBERIAN ASI EKSKLUSIF DENGAN PENURUNAN STUNTING PADA ANAK USIA 6-23 BULAN DI DESA SOSOR LONTUNG, KECAMATAN SIEMPAT NEMPU, KABUPATEN DAIRI TAHUN 2019

2019 ◽  
Vol 1 (1) ◽  
pp. 45-50
Author(s):  
Evanata Lina Sinaga ◽  
Rismahara Lubis ◽  
Yusniar Siregar ◽  
Evi Irianti
Keyword(s):  
Exclusive Breastfeeding ◽  
Significant Relationship ◽  
Failure To Thrive ◽  
Cross Sectional Study ◽  
Bivariate Analysis ◽  
Chi Square ◽  
Cross Sectional ◽  
A Value ◽  
Chi Square Test ◽  
Relationship Of

Stunting is a condition of failure to thrive in children under five due to chronic malnutrition. One cause of stunting is poor parenting patterns such as feeding in the first 2 years after birth. Exclusive breastfeeding is the best nutrition a baby receives in the first 6 months of life. The purpose of this study was to determine the relationship of exclusive breastfeeding with the decrease of stunting in children aged 6-23 months in Sosor Lontung Village, Siempat Nempu District, Dairi Regency.  This study used a cross-sectional study design. The sample of this research was children aged 6-23 months as many as 39 people. Data collection was carried out by interview and measurement of children's length / height. Univariate and bivariate data analysis used Chi Square test with ƿ-value <0.05. Based on the bivariate analysis showed that there was a significant relationship between exclusive breastfeeding and the incidence of stunting with ƿ-value 0.037. The results showed the percentage of stunting in children aged 6-23 months was greater in children who were not given exclusive breastfeeding (50%) than those who received exclusive breastfeeding (17.65%). The results of bivariate analysis showed that there was a significant relationship between exclusive breastfeeding and the incidence of stunting with a value-value of 0.037. That is, exclusive breastfeeding can reduce the risk of stunting is getting smaller. It is hoped that all babies will receive exclusive breastfeeding so that the baby can grow optimally.

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