Role of cannabinoids in various diseases: A review

Background: The plant, Cannabis sativa is heavily explored and researched with many industrial and pharmaceutical applications. The medicinal and therapeutic role of cannabis Sativa has been summarized in the paper, citing its mechanism of action and influence on the human body. Diseases like metabolic disorders, infectious diseases, and psychological disorders pose negative and long-term drastic effects on the body like neurodegeneration and other chronic system failures. Several existing literature has proved its effectiveness against such diseases. Objectives: This review aims to provide an overview of the role of cannabinoids in various diseases like metabolic disorders, infectious diseases, and psychological disorders. Method: Various e-resources like Pubmed, Science Direct, and Google Scholar were thoroughly searched and read to form a well-informed and information-heavy manuscript. Here we tried to summaries the therapeutic aspect of Cannabis sativa and its bioactive compound cannabinoids in various diseases. Result: This review highlights the various constituents which are present in Cannabis sativa, the Endocannabinoid system, and the role of cannabinoids in various diseases Conclusion: Recent research on Cannabis has suggested its role in neurodegenerative diseases, inflammation, sleep disorders, pediatric diseases, and their analgesic nature. Therefore, the authors majorly focus on the therapeutic aspect of Cannabis sativa in various diseases. The focus is also on the endocannabinoid system (ECS) and its role in fighting or preventing bacterial, parasitic, fungal, and viral infections.

Diagnostic and therapeutic applications of radiopharmaceutical agents: The medical use of radioactive iodine (I-131) therapy for hyperthyroidism treatments.

The treatment of hyperthyroidism with iodine-131 has been recognized on nuclear medicine as simple, effective and inexpensive, this kind of radiopharmaceutical is chosen by the majority of medical centers by administering a minimum effective dose enabling euthyroidism to be easily compensated as quickly as possible while avoiding radiation problems. In this mini_review, we are going to explain the diagnostic and therapeutic aspect of radiopharmaceuticals by taking an example of radioiodine I-131 and its role on hyperthyroidism treatment .

Therapeutic Indications of the Ketogenic Diet: A Integrative Review

The ketogenic diet (KD), a restrictive diet, is mainly characterized by high-fat content, low or no carbohydrate content, and low or normal protein content. This review aimed to address the main syndromes or diseases in which the therapeutic use of KD can be beneficial. One of the main clinical indications of KD has been, for some time, in the treatment of epilepsy refractory to the use of medications, with satisfactory results in the control of seizures. Recently, studies have addressed the metabolism of ketone bodies caused by KD, in the adjuvant treatment of tumors and endocrine disorders, such as diabetes and obesity, with promising results. In this work, the therapeutic aspect of KD was analyzed, as an aid in the control of pre-existing diseases, and that being a very restrictive diet with controversial effects, its use may be limited and it is not advisable to maintain it for long periods or without the proper follow-up.

Preventive aspect of ayurveda and yoga towards newly emerging disease COVID-19

The ongoing coronavirus pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV 2) and unique in various facets. The earlier experience from the past severe acute respiratory syndrome (SARS) epidemics seem to be insufficient and there is need for better strategies in public health and medical care. Ayurved & Yog are well known for their preventive and therapeutic aspect, but not getting utilized properly for prevention of Covid 19 crisis which may also be helpful as supportive therapy along with current line of management. This paper is aimed at unrevealing the role of Ayurved and Yoga guidelines established by Department of AYUSH for prevention from SARS-CoV-2 by providing help to improving the quality of supportive/prophylactic therapy in relation with their immunity.

Psychological and pedagogical methods of correction of athletes behavior (Gestalt-therapeutic aspect)

Актуальность представленной статьи определяется возможностью проанализировать на теоретическом уровне распространенность психопатологических проявлений в поведении спортсменов, причинами которых могут служить различные спектры невротических расстройств. Приводится теоретическое обоснование необходимости создания методологии проведения коррекционных мероприятий с использованием гештальт-терапевтических техник для спортсменов, находящихся в состоянии невротического расстройства в целях улучшения их подготовки в предсоревновательный период. Изучены возможности гештальт-терапии в коррекции поведения, возникающего по причине невротического развития личности в социуме. Рассматриваются основные принципы психотерапевтической работы (гештальт-терапия, гештальт-консультирование), которые описывают важные ключевые моменты работы с неврозами. Исследуются возможности гештальт-терапии в коррекции психического состояния. Предлагаются профилактические и коррекционные методы работы по коррекции невротических состояний техниками гештальт-терапии. The relevance of the presented article is determined by the possibility to analyze at the theoretical level the prevalence of psychopathological manifestations in the behavior of athletes, the reasons of which can be different spectra of neurotic disorders. The article provides a theoretical justification for the need to create a methodology for conducting corrective measures using Gestalt-therapeutic techniques for athletes who are in a state of neurotic disorder in order to improve their training in the pre-competition period. The possibilities of Gestalt-therapy in correcting behavior that occurs due to neurotic personality development in society are studied. The main principles of psychotherapeutic work (Gestalt-therapy, Gestalt-counseling) are considered, which describe important key points of working with neuroses. The possibilities of Gestalt-therapy in the correction of mental state are investigated. Preventive and corrective methods of work on the correction of neurotic states by Gestalt therapy techniques are proposed.

An Overview of the Therapeutic Aspect of Living Drugs Probiotics

The human body harbors ten times more bacterial cells than human cells. These bacterial cells form the human microbiome that plays a vital role in human health. An imbalance in the gut microbiome (i.e., dysbiosis) can result in various pathological conditions. This dysbiosis can be refurbished with the supplement of “probiotics.” Probiotics have thus been defined as non-pathogenic micro-organisms that, when ingested, exert a positive influence on host health or physiology. The most commonly used probiotic bacteria comes from two genera: Lactobacillus and Bifidobacterium. Various research findings have proposed a correlation between the alteration of microbiota (composition/activity/density) with disorders like infectious diarrhea, inflammatory bowel diseases, obesity, to name a few. The ultimate effect of administration of probiotics on health or physiology is either direct or indirect. This chapter summarizes the concept of probiotics, their therapeutic aspect along with possible mechanism of action.