Importances zootechniques et parasites internes des porcs de race locale (Sus crofa domesticus) élevés au Bénin: synthèse bibliographique

En Afrique et particulièrement au Bénin, l’élevage du porc constitue une activité génératrice de revenu. Toutefois, les acteurs de ce secteur sont confrontés à de nombreuses difficultés dont le parasitisme qui entraîne une baisse de production et de productivité. Le présent travail a pour but de faire une revue de littérature sur les parasites qui affectent l’élevage des porcs en Afrique et particulièrement au Bénin. De l’analyse des données collectées, il ressort que trois types d’élevage sont pratiqués au Bénin : l’élevage traditionnel, prédominant et pratiqué à 65%, l’élevage semi-intensif ou semi moderne à 32% et enfin l’élevage intensif ou moderne à 3%. L’amélioration des conditions d’élevage et particulièrement l’alimentation du porc indigène d’Afrique est favorable à l’expression de son potentiel zootechnique. Malgré l’optimalisation des rations, les performances zootechniques du porc local restent encore faibles par rapport à celles des races améliorées. Très peu d’étude sont abordé la prévalence des parasites internes du porc au plan national, mais parmi les parasites rapportés, on a noté : Ascaris suum, Strongyloides ransomi, Trichuris suis, le genre Hyostrongylus et d'autres parasites internes du porc. Il s’impose de mener une étude sur les parasites du porc au Bénin afin de déterminer la prévalence des différents parasites et le danger que ces derniers représentent pour le développement de cette filière. English title: Zootechnical importance and internal parasites of local pigs (Sus crofa domesticus) raised in Benin: bibliographic synthesis In Africa, and particularly in Benin, pig farming is an income-generating activity. However, the actors of this sector are confronted with many difficulties, including parasitism which leads to a decrease in production and productivity. The aim of this study is to review the literature on parasites affecting pig farming in Africa, articularly in Benin. From the analysis of the data collected, it appears that three types of livestock production are practised in Benin: traditional livestock production, which is predominant and practised at 65%, semi-intensive or semi-modern livestock production at 32% and finally intensive or modern livestock production at 3%. The improvement of breeding conditions and particularly the feeding of the indigenous African pig is favorable to the expression of its zootechnical potential. Despite the optimization of rations, the zootechnical performance of local pigs is still low compared to that of improved breeds. Very few studies have addressed the prevalence of internal parasites of pigs at the national level, but among the parasites reported were: Ascaris suum, Strongyloides ransomi, Trichuris suis, the genus Hyostrongylus and other internal parasites of pigs. It is necessary to conduct a study on pig parasites in Benin in order to determine the prevalence of the different parasites and the danger that they represent for the development of this sector.

Prevalencia coprológica de parásitos gastrointestinales en humanos y porcinos de crianza de traspatio del distrito de Zapatero, San Martín

El objetivo del presente estudio de investigación fue determinar la prevalencia de parasitismo intestinal en porcinos y humanos del Centro Poblado Menor de Bagazan, provincia de Lamas, Perú. Se colectaron 176 muestras fecales de porcinos de crianza de traspatio y 179 muestras de población humana relacionada a la crianza de estos animales. Las muestras fueron colectadas independientemente de la edad y sexo y fueron analizadas cualitativamente mediante la técnica parasitológica de flotación con solución sobresaturada de cloruro de sodio y la estimación de la carga parasitaria se realizó con el método de McMaster modificado. La prevalencia de parasitismo intestinal en los cerdos fue 28.41% (50/176), encontrándose Eimeria spp (63.07%), huevos tipo Strongylus (26.71%), Ascaris suum (12.5%), Macracanthorhynchus hirudinaceus (1.14%), Trichuris suis (0.57%) y Balantidium coli (0.57%). En el caso de los humanos, la prevalencia fue 91.6%, encontrándose Ascaris lumbricoides (34.09%), Strongyloides stercoralis (1.11%), Trichuris trichiura (2.72%) y Enterobius vermicularis (0.55%). No se determinó asociación significativa entre prevalencia parasitaria y los factores sexo y edad en porcinos.

The Worm-Specific Immune Response in Multiple Sclerosis Patients Receiving Controlled Trichuris suis Ova Immunotherapy

Considering their potent immunomodulatory properties, therapeutic applications of Trichuris suis ova (TSO) are studied as potential alternative treatment of autoimmune disorders like multiple sclerosis (MS), rheumatoid arthritis (RA), or inflammatory bowel disease (IBD). Clinical phase 1 and 2 studies have demonstrated TSO treatment to be safe and well tolerated in MS patients, however, they reported only modest clinical efficacy. We therefore addressed the cellular and humoral immune responses directed against parasite antigens in individual MS patients receiving controlled TSO treatment (2500 TSO p.o. every 2 weeks for 12 month). Peripheral blood mononuclear cells (PBMC) of MS patients treated with TSO (n = 5) or placebo (n = 6) were analyzed. A continuous increase of serum IgG and IgE antibodies specific for T. suis excretory/secretory antigens was observed up to 12 months post-treatment. This was consistent with mass cytometry analysis identifying an increase of activated HLA-DRhigh plasmablast frequencies in TSO-treated patients. While stable and comparable frequencies of total CD4+ and CD8+ T cells were detected in placebo and TSO-treated patients over time, we observed an increase of activated HLA-DR+CD4+ T cells in TSO-treated patients only. Frequencies of Gata3+ Th2 cells and Th1/Th2 ratios remained stable during TSO treatment, while Foxp3+ Treg frequencies varied greatly between individuals. Using a T. suis antigen-specific T cell expansion assay, we also detected patient-to-patient variation of antigen-specific T cell recall responses and cytokine production. In summary, MS patients receiving TSO treatment established a T. suis-specific T- and B-cell response, however, with varying degrees of T cell responses and cellular functionality across individuals, which might account for the overall miscellaneous clinical efficacy in the studied patients.

Prevalence and Risk Factors of Intestinal Parasite Infections in Greek Swine Farrow-To-Finish Farms

Intestinal parasites, helminths, and protozoa challenge health and welfare of pigs and deteriorate the sustainability of swine farms leading to monetary losses. A multicentric survey was conducted for approximately one year. Overall, 1150 fecal samples were collected from eight intensive farms in Greece at regular intervals and examined by flotation and Ziehl-Neelsen techniques. Age, season, and time of last recorded antiparasitic treatment were assessed as possible risk factors using binary regression models. The overall prevalence of intestinal parasitism in pigs was 44.7%. The most frequently detected parasites in the studied population were the protozoa Balantidium coli (37.8%), followed by Entamoeba spp. (8.3%), Cystoisospora suis (6.0%), and the nematodes Ascaris suum (3.7%), Trichuris suis (2.5%), and Oesophagostomum spp. (1.4%). Distribution of intestinal parasites in different age groups was as expected. In autumn, the prevalence of Balantidium coli infection enhanced whereas the prevalence of Entamoeba spp. and Cystoisospora suis infections increased in spring. Time of last recorded antiparasitic treatment influenced Balantidium coli and Trichuris suis infection levels. Our results demonstrated that swine intestinal parasitism in intensive farms of Greece seems to be relatively common and highlighted the importance of proper laboratory examinations, as well as the need for tailored made control programs.

The impact of certain flavourings and preservatives on the survivability of eggs of Ascaris suum and Trichuris suis

The article describes a laboratory study of nematocidal properties of flavourings with antibacterial effect against Ascaris suum (Goeze, 1782) and Trichuris suis Schrank, 1788. In the experiments, eight concentrations of food additives with antibacterial properties were used: cinnamaldehyde, benzoic acid, formic acid, linalool, citral, β-ionone. Minimum LC50 value for eggs of A. suum was observed while using cinnamaldehyde and benzoic acid – 1.62 ± 0.37% and 1.69 ± 0.14%, and for eggs of T. suis – 0.57 ± 0.03% and 1.80 ± 0.11% respectively. The lowest influence on the development of eggs of nematodes of pigs’ A. suum and T. suis was exerted by formic acid, linalool, citral and β-ionone. In eggs of A. suum and T. suis, larvae formed in 21 and 50 days even during exposure to 3% emulsions of these substances. The strongest negative impact on the eggs of parasitic nematodes was displayed by cinnamaldehyde flavouring. Further study on nematocidal properties of flavourings, as well as their mixtures, would contribute to the development of preparations which would have a strong effect on eggs and larvae of nematodes of animals and humans.

The impact of certain flavourings and preservatives on the survivability of eggs of Ascaris suum and Trichuris suis

The article describes a laboratory study of nematocidal properties of flavourings with antibacterial effect against Ascaris suum (Goeze, 1782) and Trichuris suis Schrank, 1788. In the experiments, eight concentrations of food additives with antibacterial properties were used: cinnamaldehyde, benzoic acid, formic acid, linalool, citral, β-ionone. Minimum LC50 value for eggs of A. suum was observed while using cinnamaldehyde and benzoic acid – 1.62 ± 0.37% and 1.69 ± 0.14%, and for eggs of T. suis – 0.57 ± 0.03% and 1.80 ± 0.11% respectively. The lowest influence on the development of eggs of nematodes of pigs’ A. suum and T. suis was exerted by formic acid, linalool, citral and β-ionone. In eggs of A. suum and T. suis, larvae formed in 21 and 50 days even during exposure to 3% emulsions of these substances. The strongest negative impact on the eggs of parasitic nematodes was displayed by cinnamaldehyde flavouring. Further study on nematocidal properties of flavourings, as well as their mixtures, would contribute to the development of preparations which would have a strong effect on eggs and larvae of nematodes of animals and humans.