Ethnomedicinal and traditional uses of the Ferns of Khyber Pakhtunkhwa, Pakistan

Ferns are often used by indigenous people in Khyber Pakhtunkhwa, Pakistan. This study was designed to collect the ethnomedicinal and traditional knowledge of these locals about this group of vascular plants. Forty taxa belong to nineteen genera and ten families are used in the treatment of different diseases. The Pteridaceae was the most representative family with twelve taxa (30%), followed by Athyriaceae and Dryopteridaceae with six taxa each (30%), and Thelypteridaceae with five taxa (12.5%). Regarding the genera, Adiantum, Asplenium and Dryopteris ranked first with four taxa each (30%), followed by Aleuritopteris, Diplazium, Pteris and Equisetum with three taxa each (30%), followed by Athyrium, Oeosporangium, Polystichum and Pseudophegopteris with two taxa each (20%). These taxa were commonly used in the treatment of respiratory disorders i.e. asthma, bronchitis, emphysema, pneumonia; intestinal ulcer, stomach, urinary ailments and skin disorders by the methods of decoction and infusion. Traditional knowledge about ethnomedicinal plants is a valuable and essential source for the discovery of allopathic, herbal and homeopathic medicines.

Manager or Craftsman

The chapter investigates how the ‘palace machine’ of the Qing dynasty reproduced (or systematically trained) particularly skilled bannermen as ethnically-marked official experts. By mapping out these bannermen’s education, training process, and official appointments, I explain how the court system perpetuated the administrative privilege of bannermen families and how specific skills of different generations matched the particular demands of empire building projects of the Qing dynasty in different stages. I focus on a representative family, the Wanggiyan/ Wanyan clan, generations of which served the court within the institutional framework of the Imperial Household Department. Placing this extended family in the context of peer bannermen equipped with specialized skills allows me to shed light on the larger issue of the relationship between hereditary status and specialized skills in the Qing palace machine.

Bibliometric Study of Family Studies Journals Using Journal Impact Factors, CiteScore and H-index

Although there are bibliometric studies of journals in various fields, the field of family studies remains unexplored. Using the bibliometric metrics of the two-year and five-year Journal Impact Factors, the H-index, and the newly revised CiteScore, this paper examines the relationships among these metrics in a bibliometric study of forty-four representative family studies journals. The citation data were drawn from Journal Citation Reports, Scopus, and Google Scholar. The correlation analysis found strong positive relationships on the metrics. Despite the strong correlations, discrepancies in rank orders of the journals were found. A possible explanation of noticeable discrepancy in rankings was provided, and the implications of the study for stakeholders were discussed.

Mapping bee flora in honey producing areas of the Alto Médio Canindé microregion in Piauí state, Brazil

The Brazilian state of Piauí is one of the largest producers of organic honey in the country. Although the product is made from nectar collected from natural vegetation, including several species endemic to the Caatinga, knowledge of the beekeeping potential of semiarid vegetation remains scarce, particularly in Piauí. As such, the present study aimed to map the flora of honey-producing areas of the Alto Médio microregion in Piauí. A survey was conducted of apiaries in the region and bee production in four beekeeping communities, using data provided by the Simplício Mendes Microregion Beekeeping Cooperative (COMAPI). Geographic coordinates were used to generate a map to analyze vegetation in the region and excursions were carried out in previously defined areas to survey plants visited by honeybees. The beekeeping communities in areas with greater floral density had the highest honey production. Forty plant species were collected, with the most representative family being Fabaceae, followed by Euphorbiaceae and Anacardiaceae. Most of the plants surveyed were visited by bees with the sole purpose of collecting nectar and were flowering in months with the highest honey production. Thus, creating a flowering calendar could help beekeepers make better use of the local flora.

Climbing plants from Seridó Ecological Station: diversity, interactive key and five new records from Rio Grande do Norte state, Brazil

In Brazil, Seasonally Dry Tropical Forests (SDTFs) are represented by Caatinga, which exhibits one of the greatest species richness and endemisms among the Neotropical SDTFs. However, studies of the flora of this biome remain deficient, especially in scientifically neglected areas, such as the Seridó region. Located between the states of Rio Grande do Norte (RN) and Paraíba, the Seridó region has an underestimated floristic diversity, especially for non-arboreal components such as climbers. Given this scenario, the study aimed to survey the climbers of the Seridó Ecological Station, a federal conservation unit located in the RN state, as well as to provide a multiple access online identification key. Collections were carried out from 2018 to 2019, as well as consultation of material deposited at the UFRN herbarium. In total, 56 species were listed, being 33 herbaceous and 23 woody climbers, respectively, adding 14 species of climbers to the previous checklist of the unit. Five new occurrences were found for the state of Rio Grande do Norte: Cuscuta globosa, Cuscuta partita (Convolvulaceae), Macroptilium bracteatum (Fabaceae), Heteropterys trichanthera and Tetrapterys longibracteata (Malpighiaceae), being the latest a new occurrence of the genus Tetrapterys for the state. Convolvulaceae is the most representative family (18 spp.), followed by Fabaceae (10 spp.), Apocynaceae (eight spp.) and Cucurbitaceae (five spp.). This is the first study that provides an interactive identification key for the Seridó region and for the RN state. The interactive identification key is published throughout the Xper³ platform, and can be accessed at <xper3.fr/xper3GeneratedFiles/publish/identification/-4505993480748774750/mkey.html>.

The Sez6 family inhibits complement at the level of the C3 convertase

The Sez6 family consists of Sez6, Sez6L, and Sez6L2. Its members are expressed throughout the brain and have been shown to influence synapse numbers and dendritic morphology. They are also linked to various neurological and psychiatric disorders. All Sez6 family members contain 2-3 CUB domains and 5 complement control protein (CCP) domains, suggesting that they may be involved in complement regulation. We show that all Sez6 family members inhibit C3 deposition by the classical and alterative pathways with varying degrees of efficacy. For the classical pathway, Sez6 is a strong inhibitor, Sez6L2 is a moderate inhibitor, and Sez6L is a weak inhibitor. Using Sez6L2 as the representative family member, we show that it specifically deactivates C3 convertases by accelerating the decay or dissociation of the C3 convertase components. Sez6L2 also deactivates C3 convertases of the alternative pathway by serving as a cofactor for Factor I to facilitate the cleavage of C3b. However, Sez6L2 has no cofactor activity toward C4b. In summary, the Sez6 family are novel complement regulators that inhibit C3 convertases.

Adiponectin and related C1q/TNF-related proteins bind selectively to anionic phospholipids and sphingolipids

Adiponectin (Acrp30) is an adipokine associated with protection from cardiovascular disease, insulin resistance, and inflammation. Although its effects are conventionally attributed to binding Adipor1/2 and T-cadherin, its abundance in circulation, role in ceramide metabolism, and homology to C1q suggest an overlooked role as a lipid-binding protein, possibly generalizable to other C1q/TNF-related proteins (CTRPs) and C1q family members. To investigate this, adiponectin, representative family members, and variants were expressed in Expi293 cells and tested for binding to lipids in liposomes using density centrifugation. Binding to physiological lipids were also analyzed using gradient ultracentrifugation, liquid chromatography-mass spectrometry, and shotgun lipidomics. Interestingly, adiponectin selectively bound several anionic phospholipids and sphingolipids, including phosphatidylserine, ceramide-1-phosphate, glucosylceramide, and sulfatide, via the C1q domain in an oligomerization-dependent fashion. Binding to lipids was observed in liposomes, low-density lipoproteins, cell membranes, and plasma. Other CTRPs and C1q family members (Cbln1, CTRP1, CTRP5, and CTRP13) also bound similar lipids. These findings suggest that adiponectin and CTRPs function not only as hormones, but also as lipid opsonins, as may other C1q family proteins.

Ferns and lycophytes of remnants in Amazônia Maranhense, Brazil

This work is an inventory of ferns and lycophytes of remnants in Amazônia Maranhense. The data provided are the results of collections made from 2010-2011 and 2016-2019 in various municipalities of Maranhão in the Amazonian part of the state. Sixty-four species of ferns and lycophytes, in 36 genera and 18 families, were recorded. Of these, 24 species are new records for Maranhão and four are new records for the Northeast Region of Brazil. The most representative family was Pteridaceae (23 species), followed by Polypodiaceae (7 species). The predominant life forms were terrestrial (37 species) and epiphytic (15 species); the latter is the highest number of epiphytic species recorded for a fern and lycophyte inventory in Maranhão. The data support the need for collecting ferns and lycophytes in Amazônia Maranhense to better understand the flora of these groups in the state.

The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures

The Structural Classification of Proteins (SCOP) database is a classification of protein domains organised according to their evolutionary and structural relationships. We report a major effort to increase the coverage of structural data, aiming to provide classification of almost all domain superfamilies with representatives in the PDB. We have also improved the database schema, provided a new API and modernised the web interface. This is by far the most significant update in coverage since SCOP 1.75 and builds on the advances in schema from the SCOP 2 prototype. The database is accessible from http://scop.mrc-lmb.cam.ac.uk.

Floristic Analysis and Phytosociology in an Area of Caatinga, Brazil

Studies on the composition and structure of vegetation can provide important information for decision-making and the application of forest-management techniques. The aim of this research was to analyse an area of ​​Caatinga using vegetation characterisation and forest inventory in the Rocha Eterna Community, in the district of São João do Piauí, Brazil. Simple Random Sampling was used, installing 17 sampling units of 20 x 20 m. The phytosociological parameters of the horizontal and vertical structure, the floristic diversity of the species and the timber production in the area were evaluated. Fabaceae was the most representative family. The three most representative species in the area were Senna acuruensis (Benth.) H.S. Irwin & Barneby, Sideroxylon obtusifolium (Roem. & Schult.) T. D. Penn. and Mimosa tenuiflora (Willd.) Poir. The Shannon-Weaver diversity index (H') for the area was 1.74 nats.ind-1. The estimated basal area for the area was 8.68 m².ha-1. The estimated actual volume was 36.56 m³.ha-1. Species diversity in the fragment under study was considered low.