In order to research the influence rule of the spacing distance between orifice plates to the local resistance coefficient and total local water head losses , carried out the experiment research through set the two different relative distance of orifice plates in the pressure delivery pipeline. The experimental results showed that: When the relative distance, the results of total local water head losses calculated by the traditional hydraulics formula with the real measured data, the maximal relative error was less than 3%. This shown that when the relative distance was big, it was no necessary to consider the influence of the relative distance between orifice plates. However, when the relative distance, the real measured data of the total local water losses was much smaller than the calculated data by the traditional calculation formula, the maximal relative error was reached 239.5%. It was explained that when the relative distance was relative small, existed the adjoining influence between orifice plates, so the total local water losses by the multi-orifice plates was not equal to the sum of each water head loss by the single orifice plate, and the total local head loss was not necessarily increased with the number of orifice plates increasing. Whether or not the increasing total local water head losses was closely related with the relative distance of the orifice plates. The traditional local water head loss calculation formula in the hydraulics should be corrected and modified.