Surgical outcome of congenital penile curvature treatment with corporal rotation technique

Congenital penile curvature (CPC) is a rare condition in men but has considerable impact on male sexual activity as well as their mental health. Many techniques had been proposed to manage this condition, however the corporal rotation technique had the advantage of preserving the penile length. Therefore, we conducted a study on 16 men with CPC who were treated with corporal rotation surgery to evaluate the outcome of this technique. The results showed that the mean degree of curvature was 51 ± 12.2 degree. The majority of patients had a moderate penile curvature (< 60 degree) and ventral curvature (75%). After the surgery, the residual curvature decreased significantly (from 51 ± 12.2 degree to 16.6 ± 6.34 degree with p < 0.001). We observed no remarkable changes in all penile dimensions including stretched penile length (13.6 ± 0.93cm before the surgery compared with 13.3 ± 0.89cm after the surgery with p = 0.01). Erectile function of the subjects was also significantly improved especially in the intercourse satisfaction domain.

Tadalafil Improves Erectile Dysfunction and Quality Of Life in Men with Cirrhosis: A Randomized Placebo Controlled Trial

Background and Aims: Patients with cirrhosis have high prevalence of erectile dysfunction (ED). The aim of this study was to study the efficacy and safety of tadalafil for ED in patients with cirrhosis. Methods: 140 cirrhotic males with ED were randomized into tadalafil 10 mg daily (n = 70) or placebo (n = 70) for 12 weeks. ED was diagnosed if erectile function (EF) domain score was < 25 in International Index of Erectile Function (IIEF) questionnaire. Primary outcome was proportion of patients having an increase in > 5 points in EF domain of the IIEF. Results: At end of 12 weeks, more patients in tadalafil group achieved > 5 points increase in the EF domain of the IIEF as compared to the placebo group [44(62.9%) vs. 21(30%), P < 0.001]. At the end of 12 weeks, patients receiving tadalafil had significantly more change in scores on the erectile function domain, orgasmic function domain, intercourse satisfaction domain, overall satisfaction domain, erection vaginal penetration rates and successful intercourse; significantly more decline in the GAD-7 and PHQ- 9 scores; significantly more improvement in scores of five of the eight domains of SF-36 (general health perception, vitality score, social functioning, role emotional, and mental health), and the mental component summary rates as compared to placebo. The development of side effects and the changes in HVPG were not significantly different between the two groups. Conclusions: Tadalafil therapy significantly enhanced erectile function, improved anxiety, depression and quality of life, and was well tolerated by cirrhotic men with ED. (ClinicalTrials.gov identifier number: NCT03566914; first posted date: June 25, 2018).

The 2020 ESC-ACVC quality indicators for the management of acute myocardial infarction applied to the FAST-MI registries

Aims We estimated the 2020 European Society of Cardiology-Acute Cardio Vascular Care (ESC-ACVC) quality indicators (QI) for the management of acute myocardial infarction, from three existing registries to determine the feasibility of assessment, room for improvement, association with outcomes, and suitability for centre benchmarking. Methods and results Data were extracted from three French nationwide registries, namely FAST-MI 2005, 2010, and 2015. Feasibility of assessment and room for improvement were estimated by the denominator (patients in whom QI could be measured) and numerator (patients who satisfied the QI, among those eligible). Associations between composite QIs (CQIs) and mortality were assessed by multivariate analysis. Centre benchmarking was based on the centres mean CQI, vs. the national mean. The 2020 QIs were measured in 12 660/13 130 patients from FAST-MI. Measurement feasibility ranged from 15% to 100% with greater potential for implementation with the 2020 QI set. The mean (±SD) value of the opportunity-based CQI was 0.72 ± 0.01 and attainment of the all-or-none CQI 8.5%. Both CQIs were associated with adjusted 1-year mortality. Centre categorization into low, intermediate, and high quality was feasible, and distinguished centres with differing mortality. Conclusion Most of the 2020 QI can be measured from existing registries in all domains but not in the patient’s satisfaction domain. This assessment shows potential for implementation. Both CQIs were inversely associated with one-year mortality and centre benchmarking was feasible.

Ferrans and Powers Quality of Life Index for Spinal Cord Injury: to adapt in local language

Objective To translate and culturally adapt Telugu version of Quality of Life tool among Spinal Cord Injury patients. Method It’s a prospective cross sectional study conducted at tertiary neuro centre care hospital. The English version was translated into Telugu by two expert medical professionals and cross checked by three experts in Telugu vocabulary. Nursing students who had good proficiency in reading and writing in English and Telugu languages were chosen for checking tool reliability. Initially English language was administered on satisfaction domain followed by importance domain with one month apart. After two months Telugu version was administered in same way as English version. The reliability analysis was done. Results The tool was administered on 50 nursing students. The Cronbach’s alpha for satisfaction domain was 0.97 and importance domain was 0.91, indicating excellent reliability. Conclusion The Telugu version of QOL tool had excellent reliability. Therefore it can be administered in Telugu language for evaluating the quality of life of people with spinal cord injury.

Awareness of COVID-19 and perception of work satisfaction among healthcare workers at Patan Hospital, Nepal

Introduction: Healthcare workers (HCWs) awareness of disease outbreak, and working efficiently in a changed environment is vital to fight pandemic. How an institution responds to the crisis depends on HCWs response. This study aims to find out awareness of COVID-19 and work satisfaction of HCWs at Patan Hospital (PH), Nepal. Method: A cross-sectional questionnaires base descriptive study was conducted at PH, Patan Academy of Health Sciences, Nepal, in April 2020. The HCWs were grouped in to technical staff, doctors, and support staff. There were 20 questions each in the awareness of COVID-19 and work satisfaction domain. Ethical approval was obtained. Result: Of all the staff, 223 various level staffs responded to the questionnaire. There were 80 (35.9%) technical staff, 77 (34.5%) doctors and 66 (29.6%) support staff in the study. In the technical staff group 1106 (69.2%) responses were in favour of having good awareness and 1337 (83.5%) responses were in favour of satisfaction. In the doctors’ group 1233 (80.1%) responses were in favour of having good awareness and 1000 (65%) responses were in favour of satisfaction. In the support staff group 236 (17.7%) responses were in favour of having good awareness and 347 (26.2%) responses were in favour of satisfaction. Conclusion: Our study showed that technical staff and doctors had higher levels of perception of work satisfaction and awareness for COVID-19.

Subjective Well-being of Indramayu Regency’s Fishermen

Fisherman in Indonesia is still dominated by small-scale fishermen or traditional fishermen. This condition is very vulnerable to poverty with condition is identical with low well-being. This research was conducted in Indramayu from February to May 2018 by interviewing 100 fishermen. This study aims to analyze the domain of life satisfaction and subjective well-being of fishermen because prosperity is generally measured objectively through standards made by the government. Structured questionnaires are used to find out whether they are satisfied with their life or not in certain conditions such as satisfaction with fishing gear, government policies, the environment, the relationship between them and others. Life satisfaction domain analysis is used to determine which domain is the most dominant. The method used in this study is a purposive sampling method which is a sample determination technique with certain considerations. Data analysis was performed using descriptive statistics, namely average, standard deviation, and variance. Subjective welfare levels are categorized into four classes, very poor, poor, good, and very good. The results show that Indramayu. Fishermen belong to a very good subjective well-being. Keywords: Subjective Well-being, Fishermen, Fishing Gear, Well-being domain

A Revised Version of Diabetes Quality of Life Instrument Maintaining Domains for Satisfaction, Impact, and Worry

Background. Diabetes quality of life (DQoL) instrument has been widely used to measure quality of life among diabetes patients. This study aimed to develop a revised version of DQoL instrument that incorporated issues of redundancies in the items and strengthen the basis of validity of the instrument. Methods. This was a cross-sectional study where diabetes patients were recruited from December 1, 2014, until end of March 2015 at a public health clinic in Peninsular Malaysia. A questionnaire that included patients’ information and DQoL instrument was distributed to patients. Item selection of DQoL instrument was conducted to screen and finalize the items based on issues of missing values and redundancy. Validity testing was conducted for the revised DQoL instrument based on exploratory factor analysis, confirmatory factor analysis, and Rasch analysis. Results. The pattern structure matrix yielded three domains similar to the original version with 18 items. The minimum factor loading from the structure matrix was 0.358. The item’s and person’s reliability was excellent with 0.92 and 0.84 for “satisfaction” domain, 0.98 and 0.60 for “impact” domain, and 0.99 and 0.57 for “worry” domain, respectively. Confirmatory factor analysis has dropped 5 items and the revised version of DQoL contained 13 items. Composite reliability of the revised version was computed for “satisfaction” domain (0.922; 95% CI: 0.909–0.936), “impact” domain (0.781; 95% CI: 0.745–0.818), and “worry” domain (0.794; 95% CI: 0.755–0.832). Conclusion. A revised version of DQoL that maintains the conceptualization of “satisfaction,” “impact,” and “worry” with 13 items was successfully developed.

Cultural adaptation and validation of the "Diabetes Quality of Life for Youths" measure of Ingersoll and Marrero into Brazilian culture

The aim of this study was to adapt the "Diabetes Quality of Life for Youths (DQOLY)" measure into Brazilian culture and to analyze its psychometric properties. The cross-cultural adaptation included the phases of translation, backtranslation, committee review, and pretesting. The adapted instrument was applied to 124 type 1 diabetes mellitus´adolescents. The reliability results showed adequate Cronbach's alpha coefficients (0.8695 for Satisfaction domain, 0.8658 for Impact, 0.8387 for Worries and 0.9333 for total), with the exclusion of 3 inconsistent items. The test-retests showed no significant difference between two instrument's applications in different periods (p>0.05). The validity was demonstrated by the strategies: content, convergent, factorial and discriminant. All subscales showed positive correlations between itselves (p<0.001) and with the adolescents' self-perception of their health status (p<0.001). The present study suggests that this version of the DQOLY is a reliable and valid measure for its use in Brazil.