For centuries, people have evolved novel ways of making meaning. With the passage of time, the various traditional modes of representation or meaning making have been altered and, in some cases, refined or displaced by technological advancements. In Nigeria, a growing academic interest seeks to explore the practical relevance of integrating semiotic resources, such as speech, writing, video, music, colours, or signs to create multimodal texts across a wide range of communicative acts. This chapter, therefore, examines multimodal communication practice within Nigeria's digital space, its nature, dimension, as well as how digital technologies are appropriated to enhance, not just the people's digital experience, but also create social, economic, and business opportunities for Nigeria's growing population of digital natives.