Water is life, life is water. Water is indispensably important for sustenance of life. Wetlands serve as potential water bodies, harbouring coveted bioresources, which sustain animal life. Fish is a significant bioresource for nutrition and avocation of the people. There are various types of wetlands in the Indian sub-continent. India has c 67,429 wetlands covering c 4.1 million ha. Concomitantly, c 21,723 living species of fish have been recorded out of 39,900 species of vertebrates. Of these, c 8411 are freshwater (FW) species and c 11,650 are marine. India recorded c 2500 species of fishes; of which, c 930 live in FW and c 1570 are marine. The hitherto unknown dreadful, virulent, enigmatic Epizootic Ulcerative Syndrome (EUS), has been sweeping the FW fishes in an epidemic dimension, unhindered, unimpeded and unabated, almost semi-globally; and, has been causing large-scale mortality among them, since 1988, rendering many of them endangered. Concomitantly, the outbreak of SARS-CoV-2, among the human, was first reported at Wuhan, China, in late December 2019. The first 54 reported cases of COVID-19 were observed in December 2019 at Wuhan, China, and this, subsequently, had spread across the globe. India has been facing much impacts of COVID19 pandemic since its inception in China.