Associations between exposure to ethylene oxide, job termination, and cause‐specific mortality risk

Nut consumption is associated with lower all-cause and cause-specific mortality risk and most of the survival benefits may be achieved at a relative low level of nut consumption (about 12 g d−1).

Download Full-text

Self-reported health and adult mortality risk: An analysis of cause-specific mortality

Social Science & Medicine ◽

10.1016/j.socscimed.2003.01.001 ◽

2004 ◽

Vol 59 (6) ◽

pp. 1297-1306 ◽

Cited By ~ 198

Author(s):

Maureen Reindl Benjamins ◽

Robert A Hummer ◽

Isaac W Eberstein ◽

Charles B Nam

Keyword(s):

Mortality Risk ◽

Adult Mortality ◽

Specific Mortality ◽

Reported Health

Download Full-text

THE STUDY OF RUSSIAN CIVILIAN AVIATION PILOTS’ MORTALITY

10.31089/978-5-6042929-2-1-2021-1-82-86 ◽

2021 ◽

Author(s):

I.V. Bukhtiyarov ◽

◽

E.V. Zibarev ◽

K.V. Betts

Keyword(s):

Working Conditions ◽

Mortality Risk ◽

Age Groups ◽

Mortality Rates ◽

Russian Population ◽

Standardized Mortality Ratio ◽

Long Term Effects ◽

Specific Mortality ◽

Aviation Pilots

Abstract. Introduction. The work of civilian aviation pilots is characterized by heavy psychological and emotional stress in combination with other occupational factors. Such complex of adverse working conditions appears to be a risk for functional and somatic disorders, which may subsequently be reflected in the causes and rates of mortality in the distant period. The aim of this work is to study the mortality of retired civilian aviation pilots. Methods. A prospective cohort epidemiological study of civilian aviation pilots’ mortality. The cohort included 4513 male civilian aviation pilots of Russia who completed their employment and received employment pension. The follow-up period was 10 years (01.01.2010-31.12.2019), with 22156.9 person-years obtained. The age-specific mortality rates were calculated for 5-year age groups, the mortality risk was assessed using standardized mortality ratio (SMR) with 95% confidence interval (95% CI). The comparison group was the male Russian population. Results. As of 31.12.2019, out of 4513 civilian aviation pilots, 150 people deceased (3.3%). The age-specific mortality rates in the retired pilots’ cohort were lower in all age groups compared to the male Russian population, except for the 35-39 age group. The all-cause mortality risk for civilian aviation pilots was significantly lower compared to the male Russian population, SMR=0.31 (95%CL 0.26-0.36). Conclusion. Further research is required to determine the long-term effects of working conditions on civilian aviation pilots’ health. The follow-up period for the pilots’ cohort should be increases to 20 years and more.

Download Full-text

Racial/ethnic inequities in the associations of allostatic load with all-cause and cardiovascular-specific mortality risk in U.S. adults

PLoS ONE ◽

10.1371/journal.pone.0228336 ◽

2020 ◽

Vol 15 (2) ◽

pp. e0228336

Author(s):

Luisa N. Borrell ◽

Elena Rodríguez-Álvarez ◽

Florence J. Dallo

Keyword(s):

Mortality Risk ◽

Allostatic Load ◽

Specific Mortality ◽

Racial Ethnic

Download Full-text

Association of Antioxidants Use with All-Cause and Cause-Specific Mortality: A Prospective Study of the UK Biobank

Antioxidants ◽

10.3390/antiox9121287 ◽

2020 ◽

Vol 9 (12) ◽

pp. 1287

Author(s):

Inken Behrendt ◽

Gerrit Eichner ◽

Mathias Fasshauer

Keyword(s):

Respiratory Disease ◽

Mortality Risk ◽

Cancer Mortality ◽

Primary Objective ◽

Inverse Association ◽

Uk Biobank ◽

Cancer Subtypes ◽

Specific Mortality ◽

The Uk ◽

The Impact

Prospective studies and randomized controlled trials elucidating the impact of antioxidants supplementation on mortality risk are inconclusive. The present analysis determined association between regular antioxidants use and all-cause (primary objective), as well as cause-specific, mortality in 345,626 participants of the UK Biobank cohort using Cox proportional hazard models. All models were adjusted for confounders and multiple testing. Antioxidants users were defined as participants who indicated to regularly use at least one of the following: multivitamins, vitamin C, vitamin E, selenium, and zinc. Median age of antioxidants users (n = 101,159) and non-users (n = 244,467) at baseline was 57 years. During 3.9 million person-years and a median follow-up of 11.5 years, 19,491 deaths occurred. Antioxidants use was not significantly associated with all-cause, cancer, and non-cancer mortality including several cancer and non-cancer subtypes. Interestingly, mortality risk from respiratory disease was significantly 21% lower among antioxidants users as compared to non-users (hazard ratio: 0.79; 95% confidence interval: 0.67, 0.92). In conclusion, the present study findings do not support recommendations for antioxidants supplementation to prevent all-cause, cancer, or non-cancer mortality on a population level. The significant inverse association between antioxidants use and respiratory disease mortality needs further study.

Download Full-text

A Systematic Review of Etiological Risk Factors Associated With Early Mortality Among National Football League Players

Orthopaedic Journal of Sports Medicine ◽

10.1177/2325967118813312 ◽

2018 ◽

Vol 6 (12) ◽

pp. 232596711881331 ◽

Cited By ~ 4

Author(s):

Arthur H. Owora ◽

Brittany L. Kmush ◽

Bhavneet Walia ◽

Shane Sanders

Keyword(s):

Risk Factors ◽

Systematic Review ◽

Mortality Risk ◽

National Football League ◽

The United States ◽

Early Mortality ◽

Male Population ◽

Level Of Evidence ◽

Factors Associated ◽

Specific Mortality

Background: Multiple risks predispose professional football players to adverse health outcomes and, in extreme cases, early death; however, our understanding of etiological risk factors related to early mortality is limited. Purpose: To identify etiological risk factors associated with all-cause and cause-specific mortality among National Football League (NFL) players. Study Design: Systematic review; Level of evidence, 3. Methods: Articles examining all-cause and cause-specific mortality risk factors among previous NFL players were identified by systematically searching: PubMed, PsycINFO, Web of Science, and Google Scholar from 1990 to 2017. Study eligibility and quality were evaluated using the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines. Results: A total of 801 nonduplicated studies were identified through our search strategy. Of these, 9 studies examining 11 different risk factors were included in the systematic review. Overall, the risk of all-cause and cause-specific mortality was lower among NFL players than among the general male population in the United States. Nonwhite athletes, those in power positions, and those with a high playing-time body mass index (≥30 kg/m2) were associated with elevated all-cause and cardiovascular mortality risks. Conclusion: Methodological issues associated with the examined all-cause and cause-specific mortality risk factors preclude a definitive conclusion of etiological protective or risk effects. Comparison groups less prone to selection bias (“healthy worker effect”) and a life-course approach to the evaluation of suspected risk factors are warranted to identify etiological factors associated with early mortality among NFL players.

Download Full-text

Optimal Versus Realized Trajectories of Physiological Dysregulation in Aging and Their Relation to Sex-Specific Mortality Risk

Frontiers in Public Health ◽

10.3389/fpubh.2016.00003 ◽

2016 ◽

Vol 4 ◽

Cited By ~ 21

Author(s):

Konstantin G. Arbeev ◽

Alan A. Cohen ◽

Liubov S. Arbeeva ◽

Emmanuel Milot ◽

Eric Stallard ◽

...

Keyword(s):

Mortality Risk ◽

Physiological Dysregulation ◽

Specific Mortality

Download Full-text

Unraveling the Association Between Gait and Mortality—One Step at a Time

The Journals of Gerontology Series A ◽

10.1093/gerona/glz282 ◽

2019 ◽

Vol 75 (6) ◽

pp. 1184-1190 ◽

Cited By ~ 2

Author(s):

Lisanne J Dommershuijsen ◽

Berna M Isik ◽

Sirwan K L Darweesh ◽

Jos N van der Geest ◽

M Kamran Ikram ◽

...

Keyword(s):

Mortality Risk ◽

Gait Speed ◽

Causes Of Death ◽

Health Indicators ◽

Cox Models ◽

Risk Of Mortality ◽

Increased Risk ◽

Specific Mortality ◽

One Step ◽

Base Of Support

Abstract Background Slowness of walking is one of the very first signs of aging and is considered a marker for overall health that is strongly associated with mortality risk. In this study, we sought to disentangle the clinical drivers of the association between gait and mortality. Methods We included 4,490 participants of the Rotterdam Study who underwent a gait assessment between 2009 and 2015 and were followed-up for mortality until 2018. Gait was assessed with an electronic walkway and summarized into the domains Rhythm, Phases, Variability, Pace, Tandem, Turning, and Base of Support. Cox models adjusted for age, sex, and height were built and consecutively adjusted for six categories of health indicators (lifestyle, musculoskeletal, cardiovascular, pulmonary, metabolic, and neurological). Analyses were repeated in comorbidity-free individuals. Results Multiple gait domains were associated with an increased risk of mortality, including Pace (hazard ratio (HR) per SD worse gait, adjusted for other domains: 1.34 [1.19–1.50]), Rhythm (HR: 1.12 [1.02–1.23]) and Phases (HR: 1.12 [1.03–1.21]). Similarly, a 0.1 m/s decrease in gait speed was associated with a 1.21 (1.15–1.27) times higher hazard of mortality (HR fully adjusted: 1.14 [1.08–1.20]). In a comorbidity-free subsample, the HR per 0.1 m/s decrease in gait speed was 1.25 (1.09–1.44). Cause-specific mortality analyses revealed an association between gait speed and multiple causes of death. Conclusions Several gait domains were associated with mortality risk, including Pace which primarily represents gait speed. The association between gait speed and mortality persisted after an extensive adjustment for covariates, suggesting that gait is a marker for overall health.

Download Full-text