scholarly journals Association of Polymorphisms in the HumanIL4andIL5Genes with Atopic Bronchial Asthma and Severity of the Disease

2003 ◽  
Vol 4 (3) ◽  
pp. 346-350 ◽  
Author(s):  
Maxim B. Freidin ◽  
Olga S. Kobyakova ◽  
Ludmila M. Ogorodova ◽  
Valery P. Puzyrev
Keyword(s):  
Bronchial Asthma ◽  
Clinical Course ◽  
Positive Association ◽  
Severe Form ◽  
Negative Association ◽  
Clinical Classification ◽  
Atopic Bronchial Asthma ◽  
Severity Of The Disease ◽  
The City

Two polymorphisms in theIL4(G/C 3′-UTR) andIL5(C-703T) genes were studied in a sample of families whose probands had atopic bronchial asthma (BA) (66 families, n = 183) and in a group of non-cognate individuals with the severe form of the disease (n = 34). The samples were collected from the Russian population in the city of Tomsk (Russia). Using the transmission/disequilibrium test (TDT), a significant association of allele C-703IL5with BA was established (TDT = 4.923,p= 0.007 ± 0.0007). The analysis of 40 individuals with mild asthma and 49 patients with the severe form of the disease revealed a negative association of genotype GGIL4(OR = 0.39, 95% CI = 0.15−0.99,p= 0.035), and also a trend towards a positive association of the GCIL4genotype (OR = 2.52, 95% CI = 0.98−6.57,p= 0.052) with mild BA. There was a concordance of the clinical classification of BA severity with the ‘genotype’ (McNemar'sχ2test with continuity correction constituted 0.03, d.f. = 1,p= 0.859). These results suggest that polymorphisms in theIL4andIL5genes contribute to the susceptibility to atopic BA and could determine the clinical course of the disease.

Peculiarities of the clinical course bronchial asthma in children

1998 ◽  
Vol 79 (5) ◽  
pp. 346-348
Author(s):  
V. N. Tsybulkina ◽  
G. M. Zainetdinova ◽  
G. A. Shamsutdinova ◽  
A. N. Salikhova
Keyword(s):  
Effective Treatment ◽  
Bronchial Asthma ◽  
Specific Immunotherapy ◽  
Clinical Course ◽  
Treatment Method ◽  
Young Age ◽  
Age Group ◽  
Atopic Bronchial Asthma ◽  
Increased Sensitivity ◽  
Asthma In Children

It is established that in most of patients the course of atopic bronchial asthma occurs as clinical attacks of expiratory asphyxia repeated both by day and at night. In children aged 1 to 6 the course of this disease is principally slight, medium and grave. In elder age group (715 years) the share ef graver forms of bronchial asthma increases. The disease is determined by increased sensitivity to domestic allergens. Atypical forms are found only in young age group and obviously are not connected with hypersensitivity. The specific immunotherapy is an effective treatment method of the classical atopic bronchial asthma in children aged 7 to 15.

scholarly journals Beetles and Meteorological Conditions: A Case Study

2021 ◽  
Author(s):  
Marcos Paulo Gomes Gonçalves
Keyword(s):  
Positive Association ◽  
Meteorological Conditions ◽  
Negative Association ◽  
Meteorological Variables ◽  
Agricultural Fields ◽  
Influence Of Temperature ◽  
The Relationship ◽  
The City ◽  
Animal Grazing

The meteorological factors study in the beetle population dynamics, as well as its association with vegetation, is of fundamental importance for understanding the variation that occurs in its population. Thus, it was reported the influence of temperature, humidity, insolation and precipitation on the beetles in general and it was presented a case study that examined the relationship between time and population fluctuation of curculionids in Mata de Cocal and an area used for crop rotation and animal grazing, in the city of Teresina, Brazil, from August 2011 to July 2012. It was verified that beetles populations certain are governed and conditioned by meteorological variables to a greater or lesser extent depending on the characteristics of the community itself and the biotic and abiotic environmental factors of the area where they live: the temperature that changes the its metabolic rate, the insolation and humidity that can affect its fertility and longevity can be cited as examples. From the case presented, It was found that the Curculionidae community has a positive association with precipitation and humidity and a negative association with insolation and temperature, being that in native forests curculionids are not as dependent on meteorological variables as in agricultural fields.

scholarly journals GESTATIONAL SYPHILIS IN THE LOW AMAZON MESOREGION

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Randerson José de Araujo Sousa ◽  
Adriana Vanessa Ribeiro Mafra ◽  
Nádia Vicência Do Nascimento Martins ◽  
Luanna Samara Ribeiro Mafra
Keyword(s):  
Clinical Classification ◽  
Public Agencies ◽  
Third Trimester ◽  
Microsoft Excel ◽  
Sexually Transmitted ◽  
Monetary Targeting ◽  
Epidemiological Profile ◽  
And Control ◽  
The City

Objective: This study aimed to outline the epidemiological profile of reported cases of gestational syphilis in five cities in the Lower Amazon mesoregion between 2008 and 2018. Materials and Methods: The study was descriptive, bibliographic, and retrospective with a quantitative approach. The variables used were sociodemographic and epidemiological and the data was made available by the Ministry of Health in line with the Department of Surveillance, Prevention and Control of Sexually Transmitted Infections (STDs, HIV / AIDS) and Viral Hepatitis. The collected data were tabulated and processed with the aid of Microsoft Excel® 2010 and Action 2.8 software. Results: When characterizing the epidemiological profile, 949 reported cases of gestational syphilis were observed and the city of Santarém lead with 540 notifications. The age group between 20 and 29 years (52.6%), the race/color “Parda” (815), Incomplete Elementary School (42.7%) and the clinical classification of “Primary Syphilis” (465) predominated in all five cities. The prevailing gestational age was the “third trimester” and the treatment regimen adopted was Penicillin. Furthermore, the absence of some variables makes it difficult to build an epidemiological profile and efficient monetary targeting. Conclusion: Finally, this study can contribute to decisions by public agencies responsible for health care, as well as, instigate research in this region, in an attempt to grant more visibility to existing health problems, especially in the Amazonian interiors.  

scholarly journals Clinical and pathogenetic aspects of bronchial asthma with mycotic sensitization among residents of Siberia, Yakutia and the Russian Far East

2012 ◽  
Vol 9 (1) ◽  
pp. 37-41
Author(s):  
E L Lazutkina ◽  
L M Muzychenko ◽  
Yu S Landyshev ◽  
D D Tsyrendorzhiev ◽  
T N Chaplenko
Keyword(s):  
Bronchial Asthma ◽  
Clinical Course ◽  
Russian Far East ◽  
Far East ◽  
Amur Region ◽  
Age Group ◽  
Novosibirsk Region ◽  
The Republic ◽  
The City ◽  
The Russian Far East

Background. Is to investigate clinical and pathogenetic features of bronchial asthma (BA) in residents of Siberia, Yakutia, and Russian Far East with mycotic sensitization. Materials and Methods. 45 BA patients in the age group of 24—58 year-olds have been checked. Among them 245 patients were residents of Amur region, 112 patients — residents of Novosibirsk region, and 86 — of the Republic of Yakutia (SAHA), the City of Mirniy. All the patients went through a complex clinical and allergological checkup. The results were processed with «STATISTICA 6» set of programs. Results of the research. Variation in mycotic sensitization in BA patients has proved to be region-bound. Conclusion. Mycotic sensitization in BA patients is marked by predominantly severe clinical course of bronchial asthma and high levels of IgE in the patients’ serum. In the Republic of Yakutia (SAHA) the number of such patients is higher than in Amur and Novosibirsk regions. In BA patients — residents of Amur and Novosibirsk regions — mycotic allergy is accompanied by the domestic one, while in Yakutia it is observed along with epidermal sensitization.

scholarly journals Clinical classification of bronchial asthma

1991 ◽  
Vol 103 (3) ◽  
pp. 435-445
Author(s):  
Yoshiro TANIZAKI ◽  
Hikaru KITANI ◽  
Morihiro OKAZAKI ◽  
Takashi MIFUNE ◽  
Fumihiro MITSUNOBU ◽  
...  
Keyword(s):  
Bronchial Asthma ◽  
Clinical Classification

Perceived Overprotection and Its Association With Quality of Life in Dementia

GeroPsych ◽  
2019 ◽  
Vol 32 (3) ◽  
pp. 125-134
Author(s):  
Mechthild Niemann-Mirmehdi ◽  
Andreas Häusler ◽  
Paul Gellert ◽  
Johanna Nordheim
Keyword(s):  
Quality Of Life ◽  
Patient Autonomy ◽  
Positive Association ◽  
Well Being ◽  
Negative Association ◽  
Significant Positive Association ◽  
Cross Sectional ◽  
People With Dementia ◽  
Mental Well Being

Abstract. To date, few studies have focused on perceived overprotection from the perspective of people with dementia (PwD). In the present examination, the association of perceived overprotection in PwD is examined as an autonomy-restricting factor and thus negative for their mental well-being. Cross-sectional data from the prospective DYADEM study of 82 patient/partner dyads (mean age = 74.26) were used to investigate the association between overprotection, perceived stress, depression, and quality of life (QoL). The analyses show that an overprotective contact style with PwD has a significant positive association with stress and depression, and has a negative association with QoL. The results emphasize the importance of avoiding an overprotective care style and supporting patient autonomy.

Domestic Integration and Suicide in the Provinces of Canada

Crisis ◽  
1999 ◽  
Vol 20 (2) ◽  
pp. 59-63 ◽  
Author(s):  
Antoon A. Leenaars ◽  
David Lester
Keyword(s):  
Social Factors ◽  
Positive Association ◽  
Negative Association ◽  
Birth Rates ◽  
Marriage Rates ◽  
Suicide Rates ◽  
The Social ◽  
Divorce Rates ◽  
Low Levels ◽  
Over Time

Canada's rate of suicide varies from province to province. The classical theory of suicide, which attempts to explain the social suicide rate, stems from Durkheim, who argued that low levels of social integration and regulation are associated with high rates of suicide. The present study explored whether social factors (divorce, marriage, and birth rates) do in fact predict suicide rates over time for each province (period studied: 1950-1990). The results showed a positive association between divorce rates and suicide rates, and a negative association between birth rates and suicide rates. Marriage rates showed no consistent association, an anomaly as compared to research from other nations.

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