Cultural Worldviews and Lay Interpretations of Research Findings: The Role of the Scientific Consensus

2021 ◽  
pp. 133-152
Author(s):  
Paul Tromp ◽  
Peter Achterberg
Keyword(s):  
Scientific Consensus ◽  
Cultural Worldviews ◽  
Research Findings

PERAN KELEMBAGAAN LOKAL DALAM PENGELOLAAN PERIKANAN DI ERA DESENTRALISASI

2018 ◽  
Vol 2 (1) ◽  
pp. 91
Author(s):  
Mustaqim - Mustaqim
Keyword(s):  
Phenomenological Approach ◽  
Validity And Reliability ◽  
Fishery Resources ◽  
Depth Interview ◽  
Research Findings ◽  
Interpretation Process ◽  
The Government ◽  
Critical Interpretation ◽  
Centralization And Decentralization

Abstract. The purpose of this research is to analyze the role of Panglima Laot in the management of fishery resources in Sabang Island. To be able to understand the fisheries management that involves the role of the community in the form of local institutions, a series in-depth interview, observation, as well as literature were successfully carried out to local fishery community. Since this study is a combination of qualitative and quantitative method, the data collection was analysed using phenomenological approach and critical interpretation process to see the validity and reliability of the research findings.  Referring to previous research evidence, the results show that the presence of Panglima Laot has played an important role in providing information, invitation, supervision and participation in the management of fishery resources. In addition, the role of Panglima Laot in the management of fishery resources includes carrying out customs, assisting the government, resolving conflicts in the community, preventing illegal fishing, preserving the coastal environment and fighting for the living standards of fishermen is very influential both in centralization and decentralization era.  Therefore, these findings can be categorized as a useful information for any party working in field of fishery program. 

Giscience in the Mountain Geography

2010 ◽  
Vol 27 (1-2) ◽  
pp. 81-90
Author(s):  
Krishna Poudel
Keyword(s):  
Spatial Data ◽  
Environmental Data ◽  
Temporal Data ◽  
Observation Systems ◽  
Research Findings ◽  
Temporal And Spatial ◽  
Temporal And Spatial Characteristics ◽  
Mountain Geography ◽  
Different Sources

Mountains have distinct geography and are dynamic in nature compared to the plains. 'Verticality' and 'variation' are two fundamental specificities of the mountain geography. They possess distinct temporal and spatial characteristics in a unique socio-cultural setting. There is an ever increasing need for spatial and temporal data for planning and management activities; and Geo Information (GI) Science (including Geographic Information and Earth Observation Systems). This is being recognized more and more as a common platform for integrating spatial data with social, economic and environmental data and information from different sources. This paper investigates the applicability and challenges of GISscience in the context of mountain geography with ample evidences and observations from the mountain specific publications, empirical research findings and reports. The contextual explanation of mountain geography, mountain specific problems, scientific concerns about the mountain geography, advances in GIScience, the role of GIScience for sustainable development, challenges on application of GIScience in the contexts of mountains are the points of discussion. Finally, conclusion has been made with some specific action oriented recommendations.

Sharing Seoul: Appropriating Alleys as Communal Space through Localized Sharing Practices

2020 ◽  
Vol 46 (1) ◽  
pp. 99-114
Author(s):  
Im Sik Cho ◽  
Blaž Križnik
Keyword(s):  
Community Engagement ◽  
Public Space ◽  
Social Relationship ◽  
Spatial Dimension ◽  
Urban Life ◽  
Communal Life ◽  
Relationship Networks ◽  
Research Findings ◽  
Communal Space

Sharing practices are an important part of urban life. This article examines the appropriation of alleys as communal space to understand how sharing practices are embedded in localities, how communal space is constituted and maintained, and how this sustains communal life. In this way, the article aims to understand the spatial dimension of sharing practices, and the role of communal space in strengthening social relationship networks and urban sustainability. Seowon Maeul and Samdeok Maeul in Seoul are compared in terms of their urban regeneration approaches, community engagement in planning, street improvement, and the consequences that the transformation had on the appropriation of alleys as communal space. The research findings show that community engagement in planning is as important as the provision of public space if streets are to be appropriated as communal space. Community engagement has changed residents' perception and use of alleys as a shared resource in the neighbourhood by improving their capacity to act collectively and collaborate with other stakeholders in addressing problems and opportunities in cities.

CD38 as an immunomodulator in cancer

2020 ◽  
Vol 16 (34) ◽  
pp. 2853-2861
Author(s):  
Yanli Li ◽  
Rui Yang ◽  
Limo Chen ◽  
Sufang Wu
Keyword(s):  
Multiple Myeloma ◽  
Cell Activation ◽  
Human Tissues ◽  
Transmembrane Glycoprotein ◽  
Cell Activation Marker ◽  
Research Findings ◽  
A Cell ◽  
And Function ◽  
Human Molecule

CD38 is a transmembrane glycoprotein that is widely expressed in a variety of human tissues and cells, especially those in the immune system. CD38 protein was previously considered as a cell activation marker, and today monoclonal antibodies targeting CD38 have witnessed great achievements in multiple myeloma and promoted researchers to conduct research on other tumors. In this review, we provide a wide-ranging review of the biology and function of the human molecule outside the field of myeloma. We focus mainly on current research findings to summarize and update the findings gathered from diverse areas of study. Based on these findings, we attempt to extend the role of CD38 in the context of therapy of solid tumors and expand the role of the molecule from a simple marker to an immunomodulator.

Turnover among medical clowns early in their career

2021 ◽  
Vol 30 (2) ◽  
pp. 106-116
Author(s):  
Abira Reizer ◽  
Meni Koslowsky ◽  
Rivki Antilevich-Steg
Keyword(s):  
Job Satisfaction ◽  
Individual Differences ◽  
Traumatic Experiences ◽  
Mediating Role ◽  
Humor Appreciation ◽  
Three Phase ◽  
Research Findings ◽  
Turnover Behavior ◽  
Actual Turnover

In recent years, several investigations of the medical clowning profession have appeared in the literature. However, few studies have focused on factors associated with turnover among medical clowns early in their careers. The current study examined whether individual differences in humor disposition predicted turnover behavior. Participants were 111 medical clowns in a three-phase longitudinal study. Humor disposition was measured in the first week of their training, clowns' job satisfaction two months later, and turnover six months after that. Results showed that humor appreciation decreased actual turnover through the mediating role of job satisfaction, whereas individual differences in humor creation directly decreased turnover. In addition, previous traumatic experiences moderated the associations between humor appreciation and turnover. Overall, our research findings support the notion that humor disposition can help predict which clowns remain in the hospital.

scholarly journals Role of lung and gut microbiota on lung cancer pathogenesis

2021 ◽  
Author(s):  
Yue Zhao ◽  
Yuxia Liu ◽  
Shuang Li ◽  
Zhaoyun Peng ◽  
Xiantao Liu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Gut Microbiota ◽  
Cancer Progression ◽  
Gut Microbiome ◽  
Intestinal Flora ◽  
Inflammatory Factors ◽  
Cancer Pathogenesis ◽  
Research Findings ◽  
Relationship Of

Abstract Background Lung cancer is the leading cause of cancer-related deaths worldwide (Ferlay et al., Int J Cancer 136:E359–386, 2015). In addition, lung cancer is associated with the highest mortality among all cancer types (Wu et al., Exp Ther Med 16:3004–3010, 2018). Previous studies report that microbiota play an important role in lung cancer. Notably, changes in lung and gut microbiota, are associated with progression of lung cancer. Several studies report that lung and gut microbiome promote lung cancer initiation and development by modulating metabolic pathways, inhibiting the function of immune cells, and producing pro-inflammatory factors. In addition, some factors such as microbiota dysbiosis, affect production of bacteriotoxins, genotoxicity and virulence effect, therefore, they play a key role in cancer progression. These findings imply that lung and gut microbiome are potential markers and targets for lung cancer. However, the role of microbiota in development and progression of lung cancer has not been fully explored. Purpose The aim of this study was to systemically review recent research findings on relationship of lung and gut microbiota with lung cancer. In addition, we explored gut–lung axis and potential mechanisms of lung and gut microbiota in modulating lung cancer progression. Conclusion Pulmonary and intestinal flora influence the occurrence, development, treatment and prognosis of lung cancer, and will provide novel strategies for prevention, diagnosis, and treatment of lung cancer.

scholarly journals Trust in science increases conservative support for social distancing

2021 ◽  
Vol 24 (4) ◽  
pp. 680-697
Author(s):  
Jonah Koetke ◽  
Karina Schumann ◽  
Tenelle Porter
Keyword(s):  
Public Health ◽  
Government Official ◽  
Prevention Strategies ◽  
Social Distancing ◽  
Scientific Consensus ◽  
Ideological Differences ◽  
Moderating Role ◽  
Insight Into

The COVID-19 pandemic necessitates adherence to scientifically supported prevention strategies, such as social distancing. Although most Americans support social distancing, a subset of conservatives reject the scientific consensus on this matter. We explored why some conservatives reject social distancing, focusing on how trust in science contributes to ideological differences in social distancing intentions. In two studies, we replicated recent research demonstrating that conservatives report lower support for social distancing compared to liberals. However, in Study 1 we found support for a moderating role of trust in science, such that conservatives reported stronger intentions to socially distance when they had high trust in science. In Study 2, we enhanced trust in messaging about social distancing – and in turn, social distancing intentions among conservatives – by having the messages come from a Republican (vs. unidentified) government official. These studies provide insight into how we can increase adherence to public health recommendations regarding COVID-19.

scholarly journals The Role of Biomimetic Hypoxia on Cancer Cell Behaviour in 3D Models: A Systematic Review

Cancers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1334
Author(s):  
Ye Liu ◽  
Zahra Mohri ◽  
Wissal Alsheikh ◽  
Umber Cheema
Keyword(s):  
Systematic Review ◽  
Cellular Response ◽  
3D Culture ◽  
3D Models ◽  
In Vitro Models ◽  
Research Findings ◽  
Tissue Models

The development of biomimetic, human tissue models is recognized as being an important step for transitioning in vitro research findings to the native in vivo response. Oftentimes, 2D models lack the necessary complexity to truly recapitulate cellular responses. The introduction of physiological features into 3D models informs us of how each component feature alters specific cellular response. We conducted a systematic review of research papers where the focus was the introduction of key biomimetic features into in vitro models of cancer, including 3D culture and hypoxia. We analysed outcomes from these and compiled our findings into distinct groupings to ascertain which biomimetic parameters correlated with specific responses. We found a number of biomimetic features which primed cancer cells to respond in a manner which matched in vivo response.

The role of tryptophan in hepatic encephalopathy

1993 ◽  
Vol 5 (4) ◽  
pp. 71-75
Author(s):  
C. Aaldijk ◽  
W.W. Van Den Broek ◽  
R.C. Van Der Mast
Keyword(s):  
Hepatic Encephalopathy ◽  
Clinical Picture ◽  
Serotonergic System ◽  
Pathogenetic Mechanisms ◽  
Research Findings ◽  
Glutamine Synthesis ◽  
The Brain ◽  
Tryptophan Uptake

SummaryIn this review the most important hypotheses for the occurrence of the clinical picture of hepatic encephalopathy are discussed. As possible pathogenetic mechanisms are raised: dysfunction of the serotonergic system due to an increased tryptophan uptake in the brain, an elevated intracerebral ammoniac concentration and glutamine synthesis, and a heightened intracerebral GABA-activity.The dysregulation of the serotonergic system as a consequence of the increased intracerebral tryptophan uptake is described as one of the most important pathogenetic mechanisms. The elevated intracerebral ammoniac concentration and the elevated intracerebral glutamine synthesis play in this a facilitating role. The similarity in symptomatology of the clinical picture of HE and the serotonergic syndrome support this hypothesis. Due to contradictory research findings the role of the GABA-ergic system and the occurrence of HE remains unclear.

“Experience Isn’t Everything”: How Emotion Affects the Relationship Between Experience and Cue Utilization

2018 ◽  
Vol 60 (5) ◽  
pp. 685-698 ◽  
Author(s):  
Monique Frances Crane ◽  
Sue Brouwers ◽  
Mark William Wiggins ◽  
Thomas Loveday ◽  
Kirsty Forrest ◽  
...  
Keyword(s):  
Clinical Performance ◽  
Experience Level ◽  
Cue Utilization ◽  
Practice Experience ◽  
Negative Arousal ◽  
Range Anxiety ◽  
Research Findings ◽  
Post Hoc ◽  
The Relationship

Objective: This research examined whether negative and positive arousal emotions modify the relationship between experience level and cue utilization among anesthetists. Background: The capacity of a practitioner to form precise associations between clusters of features (e.g., symptoms) and events (e.g., diagnosis) and then act on them is known as cue utilization. A common assumption is that practice experience allows opportunities for cue acquisition and cue utilization. However, this relationship is often not borne out in research findings. This study investigates the role of emotional state in this relationship. Method: An online tool (EXPERTise 2.0) was used to assess practitioner cue utilization for tasks relevant to anesthesia. The experience of positive and negative arousal emotions in the previous three days was measured, and emotion clusters were generated. Experience was measured as the composite of practice years and hours of practice experience. The moderating role of emotion on the relationship between experience and cue utilization was examined. Results: Data on 125 anesthetists (36% female) were included in the analysis. The predicted interaction between arousal emotions and the experience level emerged. In particular, post hoc analyses revealed that anxiety-related emotions facilitated the likelihood of high cue utilization in less experienced practitioners. Conclusion: The findings suggest a role for emotions in cue use and suggest a functional role for normal range anxiety emotions in a simulated work-relevant task. Application: This research illustrates the importance of understanding the potentially functional effects common negative arousal emotions may have on clinical performance, particularly for those with less experience.

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