Management of Microbial Resources in the Environment: A Broad Perspective

2013 ◽  
pp. 1-15 ◽  
Author(s):  
Abdul Malik ◽  
Farhana Masood ◽  
Elisabeth Grohmann
Keyword(s):  
Broad Perspective ◽  
Microbial Resources

Natural Bioactive Compounds As Adjuvant Therapy For Hepatitis C Infection

2020 ◽  
Vol 16 ◽  
Author(s):  
Moema S. Santana ◽  
Rute Lopes ◽  
Isabela H. Peron ◽  
Carla R. Cruz ◽  
Ana M. M. Gaspar ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Bioactive Compounds ◽  
Low Cost ◽  
Chemical Diversity ◽  
Acute Hepatitis C ◽  
Hepatitis C Infection ◽  
Middle Income ◽  
Broad Perspective ◽  
Cost Of Production

Background: Hepatitis C virus infection is a significant global health burden, which causes acute or chronic hepatitis. The acute hepatitis C is generally asymptomatic and progresses to cure, while persistent infection can progress to chronic liver disease and extrahepatic manifestations. Standard treatment is expensive, poorly tolerated, and has variable sustained virologic responses amongst the different viral genotypes. New therapies involve direct acting antivirals; however, it is also very expensive and may not be accessible for all patients worldwide. In order to provide a complementary approach to the already existing therapies, natural bioactive compounds are investigated as to their several biologic activities, such as direct antiviral properties against hepatitis C, and effects on mitigating chronic progression of the disease, which includes hepatoprotective, antioxidant, anticarcinogenic and anti-inflammatory activities; additionally, these compounds present advantages, as chemical diversity, low cost of production and milder or inexistent side effects. Objective: To present a broad perspective on hepatitis C infection, the chronic disease, and natural compounds with promising anti-HCV activity. Methods: This review consists of a systematic review study about the natural bioactive compounds as a potential therapy for hepatitis C infection. Results: The quest for natural products have yielded compounds with biologic activity, including viral replication inhibition in vitro, demonstrating antiviral activity against hepatitis C. Conclusion: One of the greatest advantages of using natural molecules from plant extracts is the low cost of production, not requiring chemical synthesis, which can lead to less expensive therapies available to low and middle-income countries.

scholarly journals Optimisation on Thermoforming of Biodegradable Poly (Lactic Acid) (PLA) by Numerical Modelling

Polymers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 654
Author(s):  
Huidong Wei
Keyword(s):  
Lactic Acid ◽  
Numerical Modelling ◽  
Temperature Profile ◽  
Food Packaging ◽  
Strong Dependence ◽  
Viscoelastic Model ◽  
Poly Lactic Acid ◽  
Strain History ◽  
Optimal Temperature ◽  
Broad Perspective

Poly (lactic acid) (PLA) has a broad perspective for manufacturing green thermoplastic products by thermoforming for its biodegradable properties. The mechanical behaviour of PLA has been demonstrated by its strong dependence on temperature and strain rate at biaxial deformation. A nonlinear viscoelastic model by the previous study was employed in a thermoforming process used for food packaging. An optimisation approach was developed by achieving the optimal temperature profile of specimens by defining multiple heating zones based on numerical modelling with finite element analysis (FEA). The forming process of a PLA product was illustrated by modelling results on shape evolution and biaxial strain history. The optimal temperature profile was suggested in scalloped zones to achieve more even thickness distribution. The sensitivity of the optimal results was addressed by checking the robustness under perturbation.

scholarly journals The Longitudinal Link between Organizational Citizenship Behaviors and Three Different Models of Happiness

2021 ◽  
Vol 18 (12) ◽  
pp. 6387
Author(s):  
Wenceslao Unanue ◽  
Eduardo Barros ◽  
Marcos Gómez
Keyword(s):  
Organizational Citizenship ◽  
Longitudinal Design ◽  
Well Being ◽  
Organizational Citizenship Behaviors ◽  
Citizenship Behaviors ◽  
Broad Perspective ◽  
Typical Sample ◽  
Eudaimonic Happiness ◽  
Over Time

A growing body of research conducted in general life settings has found positive associations between happiness and prosocial behavior. Unfortunately, equivalent studies in the workplace are lacking. Organizational citizenship behaviors (OCBs), the prosocial behaviors at work, have not been properly studied in relation to happiness, despite the positive consequences of both constructs for workers and companies. In response, our research aims to better understand this relationship from several angles. First, using a three-wave longitudinal design, we explored how OCBs and happiness are related to each other over time. Second, happiness was measured from a broad perspective, and three conceptualizations were adopted: the hedonic (e.g., positive affect and life satisfaction), the eudaimonic (e.g., relatedness and autonomy), and the flourishing (e.g., meaning and engagement) approaches. Thus, not only the prospective link between OCBs and happiness was tested, but it was also explored using the three models of happiness previously mentioned. Third, we conducted this longitudinal design in a less typical sample than previous research (i.e., Chile). We found results that supported our main hypotheses: (1) OCBs are prospective positive predictors of hedonic happiness, eudaimonic happiness, and flourishing; (2) the three models of happiness also prospectively predict OCBs. Our findings suggest that OCBs foster a broad range of happiness facets, which in turn fosters back the emergence of more OCBs, leading to a virtuous circle of prosociality and well-being in the workplace. This positive spiral benefits not only workers’ quality of life, but also organizations’ profitability and sustainability. Theoretical and applied implications for the field of Positive Organizational Psychology are discussed.

scholarly journals Cycles in Stone Mining and Copper Circulation in Europe 5500–2000 bc: A View from Space

2020 ◽  
pp. 1-22
Author(s):  
Peter Schauer ◽  
Stephen Shennan ◽  
Andrew Bevan ◽  
Sue College ◽  
Kevan Edinborough ◽  
...  
Keyword(s):  
Western Europe ◽  
General Pattern ◽  
Exchange Networks ◽  
Broad Perspective ◽  
Radiocarbon Dates ◽  
Copper Mines ◽  
The One ◽  
Demographic Trajectories ◽  
Additional Reference ◽  
The Relationship

The authors of this article consider the relationship in European prehistory between the procurement of high-quality stones (for axeheads, daggers, and other tools) on the one hand, and the early mining, crafting, and deposition of copper on the other. The data consist of radiocarbon dates for the exploitation of stone quarries, flint mines, and copper mines, and of information regarding the frequency through time of jade axeheads and copper artefacts. By adopting a broad perspective, spanning much of central-western Europe from 5500 to 2000 bc, they identify a general pattern in which the circulation of the first copper artefacts was associated with a decline in specialized stone quarrying. The latter re-emerged in certain regions when copper use decreased, before declining more permanently in the Bell Beaker phase, once copper became more generally available. Regional variations reflect the degrees of connectivity among overlapping copper exchange networks. The patterns revealed are in keeping with previous understandings, refine them through quantification and demonstrate their cyclical nature, with additional reference to likely local demographic trajectories.

scholarly journals Prevention of Ovarian Hyperstimulation Syndrome: A Review

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Vinayak Smith ◽  
Tiki Osianlis ◽  
Beverley Vollenhoven
Keyword(s):  
Gnrh Agonist ◽  
Ovulation Induction ◽  
Ovarian Hyperstimulation Syndrome ◽  
Best Practice ◽  
Antral Follicle ◽  
Antral Follicle Count ◽  
Ovarian Hyperstimulation ◽  
Management Options ◽  
Broad Perspective ◽  
Single Method

The following review aims to examine the available evidence to guide best practice in preventing ovarian hyperstimulation syndrome (OHSS). As it stands, there is no single method to completely prevent OHSS. There seems to be a benefit, however, in categorizing women based on their risk of OHSS and individualizing treatments to curtail their chances of developing the syndrome. At present, both Anti-Müllerian Hormone and the antral follicle count seem to be promising in this regard. Both available and upcoming therapies are also reviewed to give a broad perspective to clinicians with regard to management options. At present, we recommend the use of a “step-up” regimen for ovulation induction, adjunct metformin utilization, utilizing a GnRH agonist as an ovulation trigger, and cabergoline usage. A summary of recommendations is also made available for ease of clinical application. In addition, areas for potential research are also identified where relevant.

Wroe Alderson, IMP and the evolution of theory

IMP Journal ◽  
2016 ◽  
Vol 10 (3) ◽  
pp. 390-408 ◽  
Author(s):  
Lars-Erik Gadde ◽  
Kajsa Hulthén
Keyword(s):  
Design Methodology ◽  
Systems Approach ◽  
Marketing Theory ◽  
Research Attention ◽  
Broad Perspective ◽  
Content Type ◽  
Research Fields ◽  
Theoretical Structure ◽  
Specific Objective ◽  
Scientific Fields

Purpose The purpose of this paper is to analyse how theories evolve within scientific fields: why they receive attention and why they eventually become less attractive. Design/methodology/approach The paper is based on a literature review and focusses on the theoretical structure developed by Wroe Alderson. His contributions were highly appreciated and generally considered as “the” marketing theory. However, in few years his broad perspective was more or less neglected within the field where it was developed. At the same time, Alderson’s basic thinking was adopted by the evolving IMP approach. The specific objective of the study is to analyse why researchers in marketing abandoned Alderson, while IMP adopted many of his ideas. Findings The paper illustrates significant aspects of the evolution of theories. First, the paper shows how well-established conceptualisations, like Alderson’s total systems approach, may lose impact when the focus of research shifts. Alderson’s holistic framing was found too broad and all-encompassing to be useful when research attention was directed to specific aspects of marketing management and the socio-behavioural approach to distribution. Second, the paper shows in what respect IMP found support in concepts and models presented by Alderson in the challenging of fragmented mainstream framings of the business landscape. Originality/value This paper relates the rise and fall of Alderson’s concepts and frameworks to the evolution of theories of other schools-of-thought. Furthermore, the study shows how Alderson’s ideas were adapted to other research fields than where it was originally developed.

Perencanaan Pelaksanaan Dana Desa Dalam Meningkatkan Kesejahteraan Masyarakat Dalam Perspektif Ekonomi Syariah

2020 ◽  
Vol 3 (2) ◽  
pp. 120-143
Author(s):  
Fajar Royan Safarullah ◽  
Ahmad Mulyadi Kosim ◽  
Retno Triwoelandari
Keyword(s):  
Planning Process ◽  
Descriptive Analysis ◽  
Implementation Process ◽  
Broad Perspective ◽  
Cash Assistance ◽  
Physical Infrastructure ◽  
Comprehensive Development ◽  
The Subject ◽  
Village Life ◽  
The Village

            The Village law has made the village the subject of development. Villages and villagers jointly initiate village development in order to create a better livelihood and village life. Village funds as village capacity in development have the potential to improve community welfare. This Research is a qualitative research with a descriptive analysis approach in order to analyze the planning and implementation process of village funds in improving community welfare from a sharia economic perspective. Data collection techniques used are interview, observation and documentation methods. The governments, community leaders and villagers became informants so that a broad perspective was obtained about village funds and their implications for walfare. The results showed that the planning and implementation of village funds was not yet participatory, the grassroots community had not been involved. Physical infrastructure became the priority of discussion during the planning process. In an effort to improve welfare in 2019 touching the aspects of health, education, and community residence. In 2020, village funds have a greater role in increasing community income in the form the cash assistance to the community in overcoming the covid 19 pandemic. In order to achieve a comprehensive development, in the process must apply sharia economic values. The value of integrity in the devekopment process in the form of justice, trust and fulfillment of reponsibilities as well as helping each other.

Commentaries on European Contract Laws

2018 ◽  
Author(s):  
Nils Jansen ◽  
Reinhard Zimmermann
Keyword(s):  
Contract Law ◽  
Integrative Approach ◽  
Consumer Contract ◽  
European Contract ◽  
Related Services ◽  
Broad Perspective ◽  
Complex Picture ◽  
General Contract Law ◽  
Common European Sales Law ◽  
European Contract Law

The book provides rule-by-rule commentaries on European contract law (general contract law, consumer contract law, the law of sale and related services), dealing with its modern manifestations as well as its historical and comparative foundations. After the collapse of the European Commission's plans to codify European contract law it is timely to reflect on what has been achieved over the past three to four decades, and for an assessment of the current situation. In particular, the production of a bewildering number of reference texts has contributed to a complex picture of European contract laws rather than a European contract law. The present book adopts a broad perspective and an integrative approach. All relevant reference texts (from the CISG to the Draft Common European Sales Law) are critically examined and compared with each other. As far as the acquis commun (ie the traditional private law as laid down in the national codifications) is concerned, the Principles of European Contract Law have been chosen as a point of departure. The rules contained in that document have, however, been complemented with some chapters, sections, and individual provisions drawn from other sources, primarily in order to account for the quickly growing acquis communautaire in the field of consumer contract law. In addition, the book ties the discussion concerning the reference texts back to the pertinent historical and comparative background; and it thus investigates whether, and to what extent, these texts can be taken to be genuinely European in nature, ie to constitute a manifestation of a common core of European contract law. Where this is not the case, the question is asked whether, and for what reasons, they should be seen as points of departure for the further development of European contract law.

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