scholarly journals Biological Standards and Biosecurity: The Unexplored Link

2021 ◽  
pp. 59-66
Author(s):  
Manuel Porcar

AbstractThe issue of standardisation in Synthetic Biology has important implications at both the technical and governance levels. At the former, standardisation in biology (a still-ongoing process) is expected to exponentially increase the potential of synthetic biology by democratising, easing and expanding our ability to engineer life. Indeed, it has to be stressed that Synthetic Biology is -or at least aims at being- a fully engineering discipline. And engineering, from industrial to electronics, largely relies on standards. A standard is a part, piece, device or procedure with well-established properties, and which can reliably be used in a broad range of industrial applications. Standards are often considered as universal components, in such a way that their constant properties allow a world-wide use. A well-known example of standard parts are nuts and bolts. Indeed, the onset of the industrial revolution was associated with a bloom of different designs of nuts and bolts, with different sizes and thread pitch. It soon became obvious that a standardisation of nuts and bolts was required: standard nuts and bolts were born. But what about Synthetic Biology?

2023 ◽  
Vol 55 (1) ◽  
pp. 1-35
Author(s):  
Abhishek Hazra ◽  
Mainak Adhikari ◽  
Tarachand Amgoth ◽  
Satish Narayana Srirama

In the era of Industry 4.0, the Internet-of-Things (IoT) performs the driving position analogous to the initial industrial metamorphosis. IoT affords the potential to couple machine-to-machine intercommunication and real-time information-gathering within the industry domain. Hence, the enactment of IoT in the industry magnifies effective optimization, authority, and data-driven judgment. However, this field undergoes several interoperable issues, including large numbers of heterogeneous IoT gadgets, tools, software, sensing, and processing components, joining through the Internet, despite the deficiency of communication protocols and standards. Recently, various interoperable protocols, platforms, standards, and technologies are enhanced and altered according to the specifications of the applicability in industrial applications. However, there are no recent survey papers that primarily examine various interoperability issues that Industrial IoT (IIoT) faces. In this review, we investigate the conventional and recent developments of relevant state-of-the-art IIoT technologies, frameworks, and solutions for facilitating interoperability between different IIoT components. We also discuss several interoperable IIoT standards, protocols, and models for digitizing the industrial revolution. Finally, we conclude this survey with an inherent discussion of open challenges and directions for future research.


Author(s):  
Christ P. Paul ◽  
Arackal N. Jinoop ◽  
Saurav K. Nayak ◽  
Alini C. Paul

Additive manufacturing is one of the nine technologies fuelling the fourth industrial revolution (Industry 4.0). High power lasers augmented with allied digital technologies is changing the entire manufacturing scenario through metal additive manufacturing by providing feature-based design and manufacturing with the technology called laser additive manufacturing (LAM). It enables the fabrication of customized components having complex and lightweight designs with high performance in a short period. The chapter compiles the evolution and global status of LAM technology highlighting its advantages and freedoms for various industrial applications. It discusses how LAM is contributing to Industry 4.0 for the fabrication of customized engineering and prosthetic components through case studies. It compiles research, development, and deployment scenarios of this new technology in developing economies along with the future scope of the technology.


2020 ◽  
Vol 17 (3) ◽  
pp. 172988142091031
Author(s):  
Rafael Arrais ◽  
Paulo Ribeiro ◽  
Henrique Domingos ◽  
Germano Veiga

Motivated by the Fourth Industrial Revolution, there is an ever-increasing need to integrated Cyber-Physical Systems in industrial production environments. To address the demand for flexible robotics in contemporary industrial environments and the necessity to integrate robots and automation equipment in an efficient manner, an effective, bidirectional, reliable and structured data interchange mechanism is required. As an answer to these requirements, this article presents ROBIN, an open-source middleware for achieving interoperability between the Robot Operating System and CODESYS, a softPLC that can run on embedded devices and that supports a variety of fieldbuses and industrial network protocols. The referred middleware was successfully applied and tested in various industrial applications such as battery management systems, motion, robotic manipulator and safety hardware control, and horizontal integration between a mobile manipulator and a conveyor system.


Computers ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 28 ◽  
Author(s):  
Salvatore Cavalieri ◽  
Marco Giuseppe Salafia

In the context of Industry 4.0, lot of effort is being put to achieve interoperability among industrial applications. As the definition and adoption of communication standards are of paramount importance for the realization of interoperability, during the last few years different organizations have developed reference architectures to align standards in the context of the fourth industrial revolution. One of the main examples is the reference architecture model for Industry 4.0, which defines the asset administration shell as the corner stone of the interoperability between applications managing manufacturing systems. Inside Industry 4.0 there is also so much interest behind the standard open platform communications unified architecture (OPC UA), which is listed as the one recommendation for realizing the communication layer of the reference architecture model. The contribution of this paper is to give some insights behind modelling techniques that should be adopted during the definition of OPC UA Information Model exposing information of the very recent metamodel defined for the asset administration shell. All the general rationales and solutions here provided are compared with the current OPC UA-based existing representation of asset administration shell provided by literature. Specifically, differences will be pointed out giving to the reader advantages and disadvantages behind each solution.


2019 ◽  
Vol 795 ◽  
pp. 439-450
Author(s):  
Chris Timbrell ◽  
Ramesh Chandwani ◽  
Chun Lei Ma

Since the industrial revolution when a German mining engineer August Wohler first studied the frequent breaking of chains causing several casualties and developed the concept of what we now know as the S-N curve, many experimental, theoretical and software-aided simulation techniques have been developed to study ageing material behaviour and to design new materials. Over time the demands placed on new materials have required operation under more severe temperatures and loads in order to conserve natural resources and minimise emissions. Fracture mechanics based finite element algorithms to simulate 3D cracks in components / structures have proved very useful in assessing the residual life and developing repair and maintenance strategies as mandatorily required by various licensing authorities for the continuous operation of infrastructure projects in Aerospace, Power, Transportation, Oil and Chemical industries under the ever more demanding operating conditions. Here one such software tool for crack simulation of industrial applications is presented with examples including combined fatigue and time dependent crack growth under thermo-mechanical loading including hold-time and weld defect assessment with inclusion of dis-similar materials.


2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Verónica Leticia Colin ◽  
Analía Rodríguez ◽  
Héctor Antonio Cristóbal

Insecurity in the supply of fossil fuels, volatile fuel prices, and major concerns regarding climate change have sparked renewed interest in the production of fuels from renewable resources. Because of this, the use of biodiesel has grown dramatically during the last few years and is expected to increase even further in the future. Biodiesel production through the use of microbial systems has marked a turning point in the field of biofuels since it is emerging as an attractive alternative to conventional technology. Recent progress in synthetic biology has accelerated the ability to analyze, construct, and/or redesign microbial metabolic pathways with unprecedented precision, in order to permit biofuel production that is amenable to industrial applications. The review presented here focuses specifically on the role of synthetic biology in the design of microbial cell factories for efficient production of biodiesel.


PLoS ONE ◽  
2016 ◽  
Vol 11 (7) ◽  
pp. e0158447 ◽  
Author(s):  
Yafeng Song ◽  
Jonas M. Nikoloff ◽  
Gang Fu ◽  
Jingqi Chen ◽  
Qinggang Li ◽  
...  

2021 ◽  
Author(s):  
Florian Baier ◽  
Yolanda Schaerli

Synthetic biology emerged as an engineering discipline to design and construct artificial biological systems. Synthetic biological designs aim to achieve specific biological behavior, which can be exploited for biotechnological, medical and industrial purposes. In addition, mimicking natural systems using well-characterized biological parts also provides powerful experimental systems to study evolution at the molecular and systems level. A strength of synthetic biology is to go beyond nature’s toolkit, to test alternative versions and to study a particular biological system and its phenotype in isolation and in a quantitative manner. Here, we review recent work that implemented synthetic systems, ranging from simple regulatory circuits, rewired cellular networks to artificial genomes and viruses, to study fundamental evolutionary concepts. In particular, engineering, perturbing or subjecting these synthetic systems to experimental laboratory evolution provides a mechanistic understanding on important evolutionary questions, such as: Why did particular regulatory networks topologies evolve and not others? What happens if we rewire regulatory networks? Could an expanded genetic code provide an evolutionary advantage? How important is the structure of genome and number of chromosomes? Although the field of evolutionary synthetic biology is still in its teens, further advances in synthetic biology provide exciting technologies and novel systems that promise to yield fundamental insights into evolutionary principles in the near future.


Mediaevistik ◽  
2018 ◽  
Vol 31 (1) ◽  
pp. 237-238
Author(s):  
Jane Beal

In the Anthropocene geological era (which can be dated from the Industrial Revolution ca. 1780 to the present day), human beings have been polluting water world-wide, to the point that they are endangering their own lives and the fragile balances <?page nr="238"?>that should be maintained in the earth’s eco-systems. In the medieval era, human beings did not yet have the capacity to threaten their own existence through technological “advances” that could lay waste to water resources. Indeed, water – in the form of floods and storms on sea or land – was more likely to destroy humanity than humanity was to destroy water. Thus, major works of contemporary eco-criticism have focused on modern literature and culture, as does Timothy Clark’s Ecocriticism on the Edge: The Anthropocene as a Threshhold Concept (2015) and Jedidiah Purdy’s After Nature: A Politics for the Anthropocene (2015). Yet medieval literature and culture is also worthy of eco-critical analysis, for the fountain-heads of modernity spring from the medieval period, and there can be no proper understanding of historical developments in the Anthropocene era without a deeper knowledge of medieval understandings of water.


2006 ◽  
Vol 47 ◽  
pp. 228-237
Author(s):  
Heinz Werner Neumüller ◽  
G. Klaus ◽  
W. Nick

Up to now most of the efforts for developing HTS technology have been directed to devices for grid applications. However, HTS synchronous machines as motors and generators become more and more interesting within the world-wide development programs. Replacing the copper winding of the rotor by an HTS one and introducing an iron-less aircore stator winding the very compact HTS machine has less than half the weight and volume, higher efficiency and an excellent operational behavior when compared to the conventional devices. These features make HTS rotating machines very attractive for e.g. ship drives and industrial applications for the processing industry and power generation in power plants and wind parks. World-wide, HTS machines have already demonstrated their advantages and technical feasibility. The prototypes are ranging from the 5 MW low-speed high-torque propulsion motor to the high-speed 3600 rpm 4 MVA HTS generator. Feasibility studies clearly show the financial benefits when introducing high-efficient HTS wire based rotors into a large scale power generator systems. At present, most of the industry driven activities take place in the United States, Germany, Japan and Korea and are mainly directed towards applications aboard ships. Further potential applications as well as the technical and economic benefits will be discussed.


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