Global Concern for Salinity on Various Agro-Ecosystems

2019 ◽  
pp. 1-19 ◽  
Author(s):  
Ghulam Mustafa ◽  
Mohd Sayeed Akhtar ◽  
Rabia Abdullah
Keyword(s):  
Global Concern

Benzothiazole moieties and their derivatives as antimicrobial and antiviral agents: A mini-review

2020 ◽  
Vol 11 (3) ◽  
pp. 3309-3315
Author(s):  
Manahil B Elamin ◽  
Amani Abd Elrazig Salman Abd Elaziz ◽  
Emad Mohamed Abdallah
Keyword(s):  
Scientific Literature ◽  
Antiviral Agents ◽  
Antiviral Drug ◽  
Pharmaceutical Chemistry ◽  
Heterocyclic Chemistry ◽  
Antimicrobial Drugs ◽  
Benzothiazole Derivatives ◽  
Global Concern ◽  
Pharmaceutical Molecules ◽  
Heterocyclic Moiety

Heterocyclic chemistry has provided an inexhaustible source of pharmaceutical molecules. Heterocyclic compounds such as benzothiazole moieties and its derivatives area substantial class of compounds in pharmaceutical chemistry and exhibited therapeutic capabilities, such as antitumor, anticancer, antioxidant, antidiabetic, antiviral, antimicrobial, antimalarial, anthelmintic and other activities. Besides, some antibiotics such as penicillin and cephalosporin have heterocyclic moiety. The growing prevalence of multi-drug resistant pathogens represents serious global concern,which requires the development of new antimicrobial drugs. Moreover, the emergence of pandemic SARSCoV-2 causing Covid-19 disease and all these health dilemmas urge the scientific community to examine the possible antimicrobial and antiviral capacities of some bioactive benzothiazole derivatives against these severe causative agents.This mini-review highlights some recent scientific literature on different benzothiazole molecules and their derivatives. It turns out that, there are numerous synthesized benzothiazole derivatives which exhibited different mode of actions against microorganisms or viruses and accordingly suggested them as an active candidate in the discovery of new antimicrobial or antiviral agents for clinical development. The recommended bioactive benzothiazole derivatives mentioned in the current study are mainly Schiff bases, azo dyes and metal complexes benzothiazole derivatives; the starting material for most of these derivatives are 2-aminobenzothiazole although careful pharmaceutical studies should be conducted to ensure the safety and efficacy of these bioactive synthesized molecules as an antimicrobial or antiviral drug in the future.

PROGRESS OF RESEARCH IN NUTRITIONAL THERAPY FOR NEW CORONAVIRUS INFECTION (NARRATIVE REVIEW)

2020 ◽  
Vol 7 (11) ◽  
pp. 7-19
Keyword(s):  
Theoretical Study ◽  
Animal Experiments ◽  
Nutrient Status ◽  
Nutritional Therapy ◽  
Review Of The Literature ◽  
Global Concern ◽  
Coronavirus Infection ◽  
Spread Of Infection ◽  
Development Methods ◽  
Positive Effect

Objective: In this review, we highlight the importance of an optimal nutrient status to strengthen the immune system during the COVID-19 crisis, focusing on the most relevant constituents that reduce inflammation and Provide a holistic perspective nutritional therapy the new coronavirus (covid-19) to assist researchers and improving areas for future response plans to deal with these diseases, and to provide a summary of the nutrients that help stop their development. Methods: This is a theoretical study conducted through a comprehensive review of the literature and research in the research engines (PubMed), (Read) and (ELSEVIER) and other new studies published in Chinese; we obtained information nutritional treatment who contributed to increasing the immunity of patients, due to the lack of treatment for this disease. Results: Until now no effective drug for the treatment of new coronavirus, pneumonia (covid-19) has been found. The development of vaccines is still in animal experiments. Recommendations and measures to control the spread of infection and nutritional therapy are still the only way to prevent the spread of covid-19 virus. Because, People relied only on treatments that were effective on previous viruses, for example those that have been used during the SARS and MERS epidemics. Discussion: The Covid-19 virus remains a global concern and more research is needed to control it. In addition, people need to know the nutrition ingredients that have a positive effect on increasing the immunity of the human body.

COVID 19 Aftermath - A Oral Health Care Provider Prospective

2020 ◽  
Author(s):  
Reena Sirohi
Keyword(s):  
Health Care ◽  
Oral Health ◽  
Health Care Providers ◽  
Oral Health Care ◽  
Public Health Emergency ◽  
Care Providers ◽  
Close Proximity ◽  
Enormous Amount ◽  
Control And Prevention ◽  
Global Concern

The outbreak of the coronavirus disease 2019(COVID-19) is a public health emergency of global concern. Based on the data published by the Chinese Center for Disease Control and Prevention (China CDC), the majority of patients were asymptomatic or having mild symptoms but can release an enormous amount of viral load. It posed a worldwide challenge for containment of the infection of COVID-19. As, oral health care providers work in close proximity to the patients’ mouth, they are at higher risk for infection. The aim of this article is to emphasize on special measures to be taken for prevention and potential interventions.

Identification of Main Protease of Coronavirus SARS-CoV-2 (Mpro)Inhibitors from Melissa officinalis

2020 ◽  
Vol 17 ◽  
Author(s):  
Olusola O. Elekofehinti ◽  
Opeyemi Iwaloye ◽  
Courage D. Famusiwa ◽  
Olanrewaju Akinseye ◽  
Joao B. T. Rocha
Keyword(s):  
Qsar Model ◽  
Computational Approach ◽  
Melissa Officinalis ◽  
Lead Compounds ◽  
Main Protease ◽  
The World ◽  
Recent Outbreak ◽  
Global Concern ◽  
Catalytic Dyad ◽  
Potential Therapeutic Intervention

Background: he recent outbreak of Coronavirus SARS-CoV-2 (Covid-19) which has rapidly spread around the world in about three months with tens of thousands of deaths recorded so far is a global concern. An urgent need for potential therapeutic intervention is of necessity. Mpro is an attractive druggable target for the development of anti-COVID-19 drug development. Compounds previously characterized from Melissa officinalis were queried against main protease of coronavirus SARS-CoV-2 using computational approach. Results: Melitric acid A and salvanolic acid A had higher affinity than lopinavir and ivermectin using both AutodockVina and XP docking algorithms. The computational approach was employed in the generation of QSAR model using automated QSAR, and in the docking of ligands from Melissa officinalis with SARS-CoV-2 Mpro inhibitors. The best model obtained was KPLS_Radial_28 (R2 = 0.8548 and Q2=0.6474, and was used in predicting the bioactivity of the lead compounds. Molecular mechanics based MM-GBSA confirmed salvanolic acid A as the compound with the highest free energy and predicted bioactivity of 4.777; it interacted with His-41 of the catalytic dyad (Cys145-His41) of SARS-CoV-2 main protease (Mpro), as this may hinder the cutting of inactive viral protein into active ones capable of replication. Conclusion: Salvanolic acid A can be further evaluated as potential Mpro inhibitor.

COVID 19, All a Radiologist Needs to Know: A Narrative Review

2020 ◽  
Vol 16 ◽  
Author(s):  
Farzaneh Shobeirian
Keyword(s):  
Computed Tomography ◽  
Rna Viruses ◽  
Imaging Findings ◽  
Protective Measures ◽  
Infection Transmission ◽  
The World ◽  
Positive Sense ◽  
Global Concern ◽  
Interlobular Septal Thickening ◽  
Radiologic Characteristics

Background: Coronaviruses are non-segmented enveloped positive-sense single-strand RNA viruses, and COVID-19 is the seventh known coronavirus, infecting humans. Objective: As the COVID-19 continued to spread the world wildly, every radiologist or clinician needs to be familiar with its imaging findings. Methods: In this study, we reviewed available studies to provide a comprehensive statement on COVID-19 imaging findings. Results: Ground-glass opacities, linear opacities, interlobular septal thickening, consolidation, and Crazy-paving patterns are the most frequent findings in computed tomography (CT) of lungs in patients with COVID-19 pneumonia, which are mostly bilateral, multifocal, and peripheral. Staff needs to follow some rules to reduce infection transmission. Conclusion: COVID-19 pneumonia is a new global concern which has many unknown features. In this article, the radiologic characteristics of COVID-19 pneumonia are discussed. We also discussed appropriate protective measures that the radiology team should be aware of.

Seabird bycatch vulnerability in pelagic longline fisheries based on modelling of a long-term dataset

2021 ◽  
pp. 1-16
Author(s):  
CAN ZHOU ◽  
NIGEL BROTHERS
Keyword(s):  
Capture Event ◽  
Retrieval Rate ◽  
Competitive Environments ◽  
Global Concern ◽  
Competitive Species ◽  
Spatio Temporal ◽  
Longline Fisheries ◽  
Pelagic Longline

Summary The incidental mortality of seabirds in fisheries remains a serious global concern. Obtaining unbiased and accurate estimates of bycatch rates is a priority for seabird bycatch mitigation and demographic research. For measuring the capture risk of seabird interactions in fisheries, the rate of carcass retrieval from hauled gear is commonly used. However, reliability can be limited by a lack of direct capture observations and the substantial pre-haul bycatch losses known to occur, meaning incidence of seabird bycatch is underestimated. To solve this problem, a new measure (bycatch vulnerability) that links an observed interaction directly to the underlying capture event is proposed to represent the capture risk of fishery interactions by seabirds. The new measure is not affected by subsequent bycatch loss. To illustrate how to estimate and analyse bycatch vulnerability, a case study based on a long-term dataset of seabird interactions and capture confirmation is provided. Bayesian modelling and hypothesis testing were conducted to identify important bycatch risk factors. Competition was found to play a central role in determining seabird bycatch vulnerability. More competitive environments were riskier for seabirds, and larger and thus more competitive species were more at risk than smaller sized and less competitive species. Species foraging behaviour also played a role. On the other hand, no additional effect of physical oceanic condition and spatio-temporal factors on bycatch vulnerability was detected. Bycatch vulnerability is recommended as a replacement for the commonly used bycatch rate or carcass retrieval rate to measure the capture risk of an interaction. Combined with a normalized contact rate, bycatch vulnerability offers an unbiased estimate of seabird bycatch rate in pelagic longline fisheries.

scholarly journals Donation or Discount: Effect of Promotion Mode on Green Consumption Behavior

2021 ◽  
Vol 18 (4) ◽  
pp. 1912
Author(s):  
Jun Zou ◽  
Yifan Tang ◽  
Ping Qing ◽  
Han Li ◽  
Amar Razzaq
Keyword(s):  
Purchase Intention ◽  
Environmental Issues ◽  
Environmental Problems ◽  
Product Type ◽  
Mediation Effect ◽  
Green Consumption ◽  
Consumption Behavior ◽  
Conceptual Fluency ◽  
Global Concern ◽  
Practical Implications

Environmental issues are still challenging and of global concern. To improve the environmental consumption behavior of consumers, this study investigates whether the match between the promotion mode and product type can improve the conceptual fluency of consumers, so as to increase their purchase intention for green products. The results of three experiments reveal that the interaction between promotion mode and product type has a certain impact on the conceptual fluency of consumers, which can, in turn, promote their purchase intention. This research theoretically contributes to the research on green consumption by introducing promotion mode and revealing the mediation effect of conceptual fluency, it also provides some practical implications for alleviating environmental problems.

scholarly journals Challenges in Applied Human Biometeorology

Atmosphere ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 296
Author(s):  
Andreas Matzarakis ◽  
Sorin Cheval ◽  
Tzu-Ping Lin ◽  
Oded Potchter
Keyword(s):  
Climate Change ◽  
Climate Extremes ◽  
Human Biometeorology ◽  
Global Concern ◽  
Impacts Of Climate Change

Facing the impacts of climate change and urbanization, adaptation and resilience to climate extremes have become important issues of global concern. [...]

scholarly journals Microbes: Food for the Future

Foods ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 971
Author(s):  
Matilde Ciani ◽  
Antonio Lippolis ◽  
Federico Fava ◽  
Liliana Rodolfi ◽  
Alberto Niccolai ◽  
...  
Keyword(s):  
Food Production ◽  
Arable Land ◽  
Ghg Emissions ◽  
Weather Conditions ◽  
Biodiversity Loss ◽  
Negative Externalities ◽  
Agriculture Soil ◽  
Global Concern ◽  
Food Commodities ◽  
Hydrogen Oxidizing Bacteria

Current projections estimate that in 2050 about 10 billion people will inhabit the earth and food production will need to increase by more than 60%. Food security will therefore represent a matter of global concern not easily tackled with current agriculture practices and curbed by the increasing scarcity of natural resources and climate change. Disrupting technologies are urgently needed to improve the efficiency of the food production system and to reduce the negative externalities of agriculture (soil erosion, desertification, air pollution, water and soil contamination, biodiversity loss, etc.). Among the most innovative technologies, the production of microbial protein (MP) in controlled and intensive systems called “bioreactors” is receiving increasing attention from research and industry. MP has low arable land requirements, does not directly compete with crop-based food commodities, and uses fertilizers with an almost 100% efficiency. This review considers the potential and limitations of four MP sources currently tested at pilot level or sold as food or feed ingredients: hydrogen oxidizing bacteria (HOB), methanotrophs, fungi, and microalgae (cyanobacteria). The environmental impacts (energy, land, water use, and GHG emissions) of these MP sources are compared with those of plant, animal, insect, and cultured meat-based proteins. Prices are reported to address whether MP may compete with traditional protein sources. Microalgae cultivation under artificial light is discussed as a strategy to ensure independence from weather conditions, continuous operation over the year, as well as high-quality biomass. The main challenges to the spreading of MP use are discussed.

scholarly journals Impact of Domestic and Transboundary Conflicts on Militarization

2020 ◽  
Vol 1 (1) ◽  
pp. 24-35
Author(s):  
Hafiz Syed Mohsin Abbas ◽  
Xiaodong Xu ◽  
Chunxia Sun ◽  
Saif Ullah ◽  
Muhammad Ahsan Ali Raza
Keyword(s):  
High Income ◽  
Global Perspective ◽  
Fragile States ◽  
Lower Income ◽  
Security Issues ◽  
Military Equipment ◽  
Income Groups ◽  
Global Concern ◽  
Global Peace ◽  
Lower Income Countries

AbstractSecurity issues are the global concern nowadays, which triggers government spending on military equipment and supply chain. This paper analyzes the global perspective of cohesion indicators on Militarization by using 177 countries panel data from the Years 2011-2018 based on middle/lower and high-income groups. By applied OLS and Fixed Effect modelling, we explored the idea that Group Grievance and Population Growth Rate have a significant impact on Militarization in both income groups worldwide. However, middle/lower income group’s Militarization is more fragile than high-income groups due to state cohesion. It further analyses that Security Apparatus and Fractionalization Elite are significant in Middle/ lower-income countries and have an insignificant impact on Militarization in high-income countries. In the end, the study suggested that the United Nations must keenly observe the militarization trends of the less fragile states by considering global peace concerns and should play its role to resolve the bilateral conflicts in the region to maintain world peace environment.

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