Risk factors in the primary management of anorectal malformations in Northern India

2004 ◽  
Vol 20 (6) ◽  
Author(s):  
G. Chalapathi ◽  
S.K. Chowdhary ◽  
K.L.N. Rao ◽  
R. Samujh ◽  
K.L. Narasimhan ◽  
...  
HPB Surgery ◽  
1999 ◽  
Vol 11 (4) ◽  
pp. 217-224 ◽  
Author(s):  
P. Chaurasia ◽  
M. K. Thakur ◽  
H. S. Shukla

Gallbladder cancer is a common malignancy of the biliary tract. It is the fifth common malignancy of the gastrointestinal tract in United States [1] and third in Northern India [2]. Despite such high prevalence, there is scanty published literature about this disease in indexed journals. Therefore, this article is intended to provide a brief overview of gallbladder cancer risk factors, based mainly on published evidence from analytical epidemiology and recent research findings of biologists and practising oncologists. Furthermore, an attempt has been made to establish an association between different causative factors and the occurrence of the disease.


2017 ◽  
Vol 4 (2) ◽  
pp. 446
Author(s):  
Amit Kumar ◽  
Onkar Nath Rai

Background: Stroke is one of the leading causes of death and disability worldwide. The aim of the study was to find out the incidence of different types of strokes and the associated risk factors and to establish the role of different investigations in patients of stroke.Methods: The study dealt with 100 patients of stroke who were admitted to B. R. D. Medical College, Gorakhpur, India. Each patient was analyzed in detail about clinical presentation and the investigations were aimed to establish the pathologic type of stroke and estimation of risk factors.Results: Stroke incidence was more in males (Male: Female= 1.43:1). Maximum incidence of stroke was in 6th decade (32%) followed by 7th decade (30%). Among modifiable risk factors, history of hypertension was the commonest (51%) followed by smoking (36% patients) exclusively, found in males. Hemiparesis was the most common presentation (95%) followed by altered sensorium (55%). Chest X-ray was abnormal in 16% patients, abnormal ECG was found in 27% patients and abnormal lipid values were found in 54 patients.Conclusions: Apart from control of hypertension and diabetes, abnormal lipid profile remains an important modifiable risk factor for stroke.


2022 ◽  
Author(s):  
Tamoghna Ghosh ◽  
Tejas M Suri ◽  
Kana Ram Jat ◽  
Aditya Kumar Gupta ◽  
Sushma Bhatnagar ◽  
...  

Introduction: There is a lack of studies in adolescents with COVID-19 from developing countries. We aimed to describe the clinical profile and risk factors for severe disease in adolescents hospitalized with COVID-19. Methods: A retrospective analysis of a prospectively admitted cohort of COVID-19 patients was performed at a tertiary hospital in north India. Adolescents aged 12 to 18 years who were hospitalized during the first wave (March 2020 to December 2020) and the second wave (March 2021 to June 2021) of the pandemic were included. Data on the demographic details, clinical presentation, laboratory parameters, disease severity at admission, treatments received, and in-hospital outcomes were retrieved and logistic regression was used to identify the risk factors for occurrence of moderate or severe disease. Results: The study included 197 adolescents with median (IQR) age 15 (13-17) years, of whom 117 (59.4%) were male. Among these, 170 (86.3%) were admitted during the 1st wave. Underlying comorbidities were present in 9 (4.6%) patients. At the time of hospital admission, 60 (30.9%) patients were asymptomatic. In the severity grading, 148 (84.6%) had mild, 16 (9.1%) had moderate, and 11 (6.3%) had severe disease. Fever (14.9%) and cough (14.9%) were the most commonly encountered symptoms. The median (IQR) duration of hospital stay was 10 (8-13) days and 6 (3.1%) patients died in hospital. The odds of moderate to severe disease were 3.8 for second wave, 1.9 for fever and 1.1 for raised C reactive protein (CRP). Conclusion: In our single-center study from northern India, adolescents admitted with COVID-19 had predominantly asymptomatic or mild disease. Admission during the second wave of COVID-19 pandemic, presence of fever and raised CRP were risk factors for moderate or severe disease.


Author(s):  
Naina Kumar ◽  
Ashu Yadav

Background: Puerperal sepsis is a major cause of maternal morbidity, mortality. Present study was conducted to know burden of severe puerperal sepsis, risk factors, maternal outcome.  Methods: Present observational cohort study was conducted in the Obstetrics and Gynecology department of rural tertiary center of Northern India over eight months (1st January-31st July 2018). All women who had delivered or aborted in an institution or those referred from outside within 42 days of delivery/abortion having clinical features, investigations suggestive of puerperal sepsis were enrolled. Socio-demographic factors, clinical features, examination findings, investigations, details of antecedent pregnancy, complications, risk factors, and maternal outcome were recorded. Statistical analysis was done using SPSS version 22 software.Results: A total of 66 cases with severe puerperal sepsis were observed during the study period of which 55 (83.3%) were referred from outside. The most common mode of delivery in antecedent pregnancy was vaginal (42.4%) followed by cesarean section (33.3%) and one (1.5%) forceps delivery. There were 15 (22.7%) post-abortal cases. Maternal anemia was found to be significantly linked with sepsis and adverse maternal outcome (p<0.05). Most common presenting features were fever (100%), tachycardia (100%), breathlessness (100%), malodourous vaginal discharge (100%), abdominal distention (53.0%), scar infection (16.7%), vaginal or rectal bleeding (16.7%), peritonitis (27.3%), septic shock (12.1%). A total of 38 (57.6%) cases required surgical intervention with seven (10.6%) developing multiorgan failure and 15 (22.7%) succumbed to death.Conclusions: Though puerperal sepsis is a preventable condition, it continues to be one of the major causes of maternal morbidity, mortality.


Author(s):  
Fareha Khatoon ◽  
Aruna Nigam ◽  
Neela Sharma ◽  
Reena Srivastava ◽  
Renu Sangal ◽  
...  

2021 ◽  
pp. 48-50
Author(s):  
Kajaldeep Kaur ◽  
Gursharn Singh

BACKGROUND: Retinopathy of prematurity (ROP) is a multifactorial retinal vaso-proliferative disorder which remains a leading cause of childhood blindness worldwide despite improvements in neonatal care and management guidelines. This study was conducted to determine the incidence of ROP among preterm neonates and to determine the risk factors. METHODS: All preterm infants with birth weight <1750 gm and gestation <34 weeks were screened for ROP at 4 weeks of birth for rst screening. Prenatal and postnatal risk factors, neonatal problems, treatment given, procedures and interventions done during stay in neonatal intensive care unit were recorded as per the proforma. The data from the study was systematically collected, compiled and statistically analyzed with SPSS Statistics-26 version to draw relevant conclusions. RESULTS: The incidence of ROP in 89 infants who were screened was 44%. The mean gestational age of babies with ROP was 32 weeks. In our study, pneumonia, apnea, sepsis, thrombocytopenia, NEC, shock, acidosis, IVH, BPD, the use of Bubble CPAP, Venti-CPAP and mechanical ventilator, the vasopressor use and blood transfusion were signicant risk factors. CONCLUSIONS: The incidence of ROP was signicantly higher in babies <34 weeks. It was observed in our that lower the birth weight and lower the gestational age, higher is the risk for the development of ROP. Careful and timed retinal examination of all at risk infants will minimize the development of ROP and later on blindness.


2021 ◽  
pp. 56-58
Author(s):  
Monisha SP ◽  
Prempal Kaur ◽  
Karamjit Singh ◽  
Ashwani Kumar ◽  
Upasna Ajmani

Retinopathy of prematurity (ROP) is one of the major cause of the preventable childhood blindness worldwide. One year prospective interventional study was conducted in a tertiary care centre in Northern India. All neonates with birth weight ≤ 2000 grams with gestational age ≤35 weeks were screened for ROP and divided into two groups, infants with birth weight <1750 grams (Group A) and ≥1750 grams (Group B). Prevalence of ROP, risk factors and laser treatment outcomes were compared between two groups. Of 191 neonates screened, 61(31.93%) developed ROP, out of which Infants with very low birth weight were at signicantly higher risk of developing severe ROP requiring treatment. In addition, high concentration and uctuating oxygen administration, sepsis, shock, intravenous uids >10 days were observed to be statistically signicant risk factors in infants <1750 grams. Timely screening and early treatment of threshold ROP results in desirable structural and functional outcome.


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