Thyroidectomy for thyroid cancer via transareola single-site endoscopic approach: results of a case-match study with large-scale population

Author(s):  
Juyong Liang ◽  
Ling Zhan ◽  
Ming Xuan ◽  
Qiwu Zhao ◽  
Lingxie Chen ◽  
...  
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Youn Young Park ◽  
Kil‑yong Lee ◽  
Seong Taek Oh ◽  
Sang Hyun Park ◽  
Kyung Do Han ◽  
...  

An amendment to this paper has been published and can be accessed via a link at the top of the paper.


Author(s):  
Yanbing Bai ◽  
Lu Sun ◽  
Haoyu Liu ◽  
Chao Xie

Large-scale population movements can turn local diseases into widespread epidemics. Grasping the characteristic of the population flow in the context of the COVID-19 is of great significance for providing information to epidemiology and formulating scientific and reasonable prevention and control policies. Especially in the post-COVID-19 phase, it is essential to maintain the achievement of the fight against the epidemic. Previous research focuses on flight and railway passenger travel behavior and patterns, but China also has numerous suburban residents with a not-high economic level; investigating their travel behaviors is significant for national stability. However, estimating the impacts of the COVID-19 for suburban residents’ travel behaviors remains challenging because of lacking apposite data. Here we submit bus ticketing data including approximately 26,000,000 records from April 2020–August 2020 for 2705 stations. Our results indicate that Suburban residents in Chinese Southern regions are more likely to travel by bus, and travel frequency is higher. Associated with the economic level, we find that residents in the economically developed region more likely to travel or carry out various social activities. Considering from the perspective of the traveling crowd, we find that men and young people are easier to travel by bus; however, they are exactly the main workforce. The indication of our findings is that suburban residents’ travel behavior is affected profoundly by economy and consistent with the inherent behavior patterns before the COVID-19 outbreak. We use typical regions as verification and it is indeed the case.


2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Weiqing Liu ◽  
Shumin Ma ◽  
Lei Liang ◽  
Zhiyong Kou ◽  
Hongbin Zhang ◽  
...  

Abstract Background Studies on the XRCC3 rs1799794 polymorphism show that this polymorphism is involved in a variety of cancers, but its specific relationships or effects are not consistent. The purpose of this meta-analysis was to investigate the association between rs1799794 polymorphism and susceptibility to cancer. Methods PubMed, Embase, the Cochrane Library, Web of Science, and Scopus were searched for eligible studies through June 11, 2019. All analyses were performed with Stata 14.0. Subgroup analyses were performed by cancer type, ethnicity, source of control, and detection method. A total of 37 studies with 23,537 cases and 30,649 controls were included in this meta-analysis. Results XRCC3 rs1799794 increased cancer risk in the dominant model and heterozygous model (GG + AG vs. AA: odds ratio [OR] = 1.04, 95% confidence interval [CI] = 1.00–1.08, P = 0.051; AG vs. AA: OR = 1.05, 95% CI = 1.00–1.01, P = 0.015). The existence of rs1799794 increased the risk of breast cancer and thyroid cancer, but reduced the risk of ovarian cancer. In addition, rs1799794 increased the risk of cancer in the Caucasian population. Conclusion This meta-analysis confirms that XRCC3 rs1799794 is related to cancer risk, especially increased risk for breast cancer and thyroid cancer and reduced risk for ovarian cancer. However, well-designed large-scale studies are required to further evaluate the results.


BMJ Open ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. e028843 ◽  
Author(s):  
Danmeng Liu ◽  
Yue Cheng ◽  
Shaonong Dang ◽  
Duolao Wang ◽  
Yaling Zhao ◽  
...  

ObjectivesTo report the situation of maternal micronutrient supplementation before and during pregnancy in Northwest China and to examine the rates of and factors related to the adherence to micronutrient supplementation among pregnant women in this region, where dietary micronutrient intake is commonly insufficient.DesignA large-scale population-based cross-sectional survey.SettingTwenty counties and ten districts of Shaanxi Province.ParticipantsA sample of 30 027 women were selected using a stratified multistage random sampling method. A total of 28 678 women were chosen for the final analysis after excluding those who did not provide clear information about nutritional supplementation before and during pregnancy.Main outcome measuresMaternal adherence to micronutrient supplementation (high and low) were the outcomes. They were determined by the start time and duration of use according to Chinese guidelines (for folic acid (FA) supplements) and WHO recommendations (for iron, calcium and multiple-micronutrient (MMN) supplements).ResultsIn total, 83.9% of women took at least one kind of micronutrient supplement before or during pregnancy. FA (67.6%) and calcium (57.5%) were the primarily used micronutrient supplements; few participants used MMN (14.0%) or iron (5.4%). Adherence to supplementation of all micronutrients was low (7.4% for FA, 0.6% for iron, 11.7% for calcium and 2.7% for MMN). Higher educational levels, higher income levels, urban residence and better antenatal care (including pregnancy consultation and a higher frequency of antenatal visits) were associated with high adherence to micronutrient supplementation.ConclusionMaternal micronutrient supplementation before and during pregnancy in Northwest China was way below standards recommended by the Chinese guidelines or WHO. Targeted health education and future nutritional guidelines are suggested to improve this situation, especially in pregnant women with disadvantaged sociodemographic conditions.


2017 ◽  
Vol 53 (86) ◽  
pp. 11733-11746 ◽  
Author(s):  
Grazia Malta ◽  
Simon J. Freakley ◽  
Simon A. Kondrat ◽  
Graham J. Hutchings

The replacement of mercuric chloride in the production of vinyl chloride monomer, a precursor to PVC, would greatly reduce the environmental impact of this large scale industrial process.


2006 ◽  
Vol 15 (6) ◽  
pp. 1507-1517 ◽  
Author(s):  
MARIE-FRANCE OSTROWSKI ◽  
JACQUES DAVID ◽  
SYLVAIN SANTONI ◽  
HEATHER MCKHANN ◽  
XAVIER REBOUD ◽  
...  

1999 ◽  
Vol 382 ◽  
pp. 307-329 ◽  
Author(s):  
JUDITH K. FOSS ◽  
K. B. M. Q. ZAMAN

The large- and small-scale vortical motions produced by ‘delta tabs’ in a two-stream shear layer have been studied experimentally. An increase in mixing was observed when the base of the triangular shaped tab was affixed to the trailing edge of the splitter plate and the apex was pitched at some angle with respect to the flow axis. Such an arrangement produced a pair of counter-rotating streamwise vortices. Hot-wire measurements detailed the velocity, time-averaged vorticity (Ωx) and small-scale turbulence features in the three-dimensional space downstream of the tabs. The small-scale structures, whose scale corresponds to that of the peak in the dissipation spectrum, were identified and counted using the peak-valley-counting technique. The optimal pitch angle, θ, for a single tab and the optimal spanwise spacing, S, for a multiple tab array were identified. Since the goal was to increase mixing, the optimal tab configuration was determined from two properties of the flow field: (i) the large-scale motions with the maximum Ωx, and (ii) the largest number of small-scale motions in a given time period. The peak streamwise vorticity magnitude [mid ]Ωx−max[mid ] was found to have a unique relationship with the tab pitch angle. Furthermore, for all cases examined, the overall small-scale population was found to correlate directly with [mid ]Ωx−max[mid ]. Both quantities peaked at θ≈±45°. It is interesting to note that the peak magnitude of the corresponding circulation in the cross-sectional plane occurred for θ≈±90°. For an array of tabs, the two quantities also depended on the tab spacing. An array of contiguous tabs acted as a solid deflector producing the weakest streamwise vortices and the least small-scale population. For the measurement range covered, the optimal spacing was found to be S≈1.5 tab widths.


2020 ◽  
Author(s):  
Fayyaz Minhas ◽  
Dimitris Grammatopoulos ◽  
Lawrence Young ◽  
Imran Amin ◽  
David Snead ◽  
...  

AbstractOne of the challenges in the current COVID-19 crisis is the time and cost of performing tests especially for large-scale population surveillance. Since, the probability of testing positive in large population studies is expected to be small (<15%), therefore, most of the test outcomes will be negative. Here, we propose the use of agglomerative sampling which can prune out multiple negative cases in a single test by intelligently combining samples from different individuals. The proposed scheme builds on the assumption that samples from the population may not be independent of each other. Our simulation results show that the proposed sampling strategy can significantly increase testing capacity under resource constraints: on average, a saving of ~40% tests can be expected assuming a positive test probability of 10% across the given samples. The proposed scheme can also be used in conjunction with heuristic or Machine Learning guided clustering for improving the efficiency of large-scale testing further. The code for generating the simulation results for this work is available here: https://github.com/foxtrotmike/AS.


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