scholarly journals Mechanical homeostasis in tissue equivalents: a review

2021 ◽  
Author(s):  
Jonas F. Eichinger ◽  
Lea J. Haeusel ◽  
Daniel Paukner ◽  
Roland C. Aydin ◽  
Jay D. Humphrey ◽  
...  
Keyword(s):  
Multiple Scales ◽  
Experimental Studies ◽  
Biological Tissues ◽  
Future Research ◽  
Collagen Gels ◽  
Tissue Equivalents ◽  
Current State ◽  
Open Questions ◽  
Mechanical Homeostasis ◽  
State Of Research

AbstractThere is substantial evidence that growth and remodeling of load bearing soft biological tissues is to a large extent controlled by mechanical factors. Mechanical homeostasis, which describes the natural tendency of such tissues to establish, maintain, or restore a preferred mechanical state, is thought to be one mechanism by which such control is achieved across multiple scales. Yet, many questions remain regarding what promotes or prevents homeostasis. Tissue equivalents, such as collagen gels seeded with living cells, have become an important tool to address these open questions under well-defined, though limited, conditions. This article briefly reviews the current state of research in this area. It summarizes, categorizes, and compares experimental observations from the literature that focus on the development of tension in tissue equivalents. It focuses primarily on uniaxial and biaxial experimental studies, which are well-suited for quantifying interactions between mechanics and biology. The article concludes with a brief discussion of key questions for future research in this field.

Second language structural priming: A critical review and directions for future research

2017 ◽  
Vol 34 (4) ◽  
pp. 539-552 ◽  
Author(s):  
Carrie N. Jackson
Keyword(s):  
Second Language ◽  
Future Research ◽  
Structural Priming ◽  
Cognitive Mechanisms ◽  
L2 Acquisition ◽  
Current State ◽  
Current Review ◽  
Open Questions ◽  
Key Issues ◽  
State Of Research

The last 15 years has seen a tremendous growth in research on structural priming among second language (L2) speakers. Structural priming is the phenomenon whereby speakers are more likely to repeat a structure they have recently heard or produced. Research on L2 structural priming speaks to key issues regarding the underlying linguistic and cognitive mechanisms that support L2 acquisition and use, and the extent to which lexical and grammatical information are shared across an L2 speaker’s languages. As the number of researchers investigating L2 priming and its implications for L2 learning continues to grow, it is important to assess the current state of research in this area and establish directions for continued inquiry. The goal of the current review is to provide an overview of recent research on within-language L2 structural priming, with an eye towards the open questions that remain.

Meinungsbildung in der Netzöffentlichkeit

2019 ◽  
Keyword(s):  
Social Media ◽  
Public Communication ◽  
Future Research ◽  
Digital Revolution ◽  
The Public ◽  
Empirical Basis ◽  
Current State ◽  
Open Questions ◽  
State Of Research

This volume offers insights into current research on the reception and effects of the digital revolution in public communication in the field of communication science. The contributions it contains deal with questions about the use of news on Facebook, the articulation of opinions on the public Net and the influencing of opinions on social media (e.g. by influencers). They document the current state of research and knowledge in this field, answer current open questions on an empirical basis and provide suggestions for future research. With contributions by Patrick Weber, Frank Mangold, Miriam Steiner, Melanie Magin, Birgit Stark, Pascal Jürgens, Anna Sophie Kümpel, Larissa Leonhard, Veronika Karnowski, Claudia Wilhelm, Ines Engelmann, Stefan Geiß, German Neubaum, Manuel Cargnino, Davina Berthelé, Priska Breves, Helene Schüler, Benedikt Spangardt, Kerstin Thummes

A Review of Issues in Gamified Surveys

2016 ◽  
Vol 35 (2) ◽  
pp. 147-166 ◽  
Author(s):  
Florian Keusch ◽  
Chan Zhang
Keyword(s):  
Behavioral Outcomes ◽  
Experimental Studies ◽  
Research Literature ◽  
Future Research ◽  
Web Surveys ◽  
Survey Quality ◽  
Current State ◽  
Unpublished Studies ◽  
State Of Research ◽  
Game Elements

The term “gamification” is used for a wide variety of techniques aimed to increase respondent engagement while filling out web surveys. Suggested approaches range from rephrasing questions to sound more game-like to embedding the entire survey into a game where respondent avatars adventure through a fantasy land while answering survey questions. So far, only a few experimental studies regarding the influence of gamification on survey responding have been published in peer-reviewed journals. This article systematically reviews the current research literature on gamification in surveys by first answering the question as to what gamification entails in the context of web surveys by identifying relevant gamification elements. Next, the article discusses how these elements could influence survey data quality using the Total Survey Error framework. Finally, a systematic review of empirical evidence on gamified surveys from published and unpublished studies is provided. While most studies found in our literature review reported a positive effect of using game elements, such as challenges, story/narrative, rewards, goals/objectives, and badges, on psychological outcomes among survey respondents (e.g., fun, interest, satisfaction), the influence of these elements on behavioral outcomes (e.g., completion and break-offs, item omission, satisficing, responses) and, therefore, survey quality is more unclear. This article informs survey researchers and practitioners of the current state of research on survey gamification and identifies potential areas for future research.

scholarly journals Hepatic stellate cells: current state and open questions

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Claus Kordes ◽  
Hans H. Bock ◽  
Doreen Reichert ◽  
Petra May ◽  
Dieter Häussinger
Keyword(s):  
Hepatic Stellate Cells ◽  
Stellate Cells ◽  
Essential Elements ◽  
Future Research ◽  
Heinrich Heine ◽  
Current State ◽  
Open Questions ◽  
Sinusoidal Endothelium ◽  
Cell Niche ◽  
Space Of Disse

Abstract This review article summarizes 20 years of our research on hepatic stellate cells within the framework of two collaborative research centers CRC575 and CRC974 at the Heinrich Heine University. Over this period, stellate cells were identified for the first time as mesenchymal stem cells of the liver, and important functions of these cells in the context of liver regeneration were discovered. Furthermore, it was determined that the space of Disse – bounded by the sinusoidal endothelium and hepatocytes – functions as a stem cell niche for stellate cells. Essential elements of this niche that control the maintenance of hepatic stellate cells have been identified alongside their impairment with age. This article aims to highlight previous studies on stellate cells and critically examine and identify open questions and future research directions.

scholarly journals Agile Transformation at Scale: A Tertiary Study

2021 ◽  
pp. 3-11
Author(s):  
Suddhasvatta Das ◽  
Kevin Gary
Keyword(s):  
Large Scale ◽  
Software Industry ◽  
Future Research ◽  
Small Scale ◽  
Agile Processes ◽  
Current State ◽  
Research Findings ◽  
State Of Research ◽  
Agile Software ◽  
Tertiary Study

AbstractDue to the fast-paced nature of the software industry and the success of small agile projects, researchers and practitioners are interested in scaling agile processes to larger projects. Agile software development (ASD) has been growing in popularity for over two decades. With the success of small-scale agile transformation, organizations started to focus on scaling agile. There is a scarcity of literature in this field making it harder to find plausible evidence to identify the science behind large scale agile transformation. The objective of this paper is to present a better understanding of the current state of research in the field of scaled agile transformation and explore research gaps. This tertiary study identifies seven relevant peer reviewed studies and reports research findings and future research avenues.

scholarly journals Modelling of framework materials at multiple scales: current practices and open questions

2018 ◽  
Author(s):  
Guillaume Fraux ◽  
Siwar Chibani ◽  
François-Xavier Coudert
Keyword(s):  
Atomistic Simulation ◽  
Multiple Scales ◽  
Point Of View ◽  
Computational Point ◽  
Framework Materials ◽  
New Methods ◽  
Modelling Framework ◽  
Current State ◽  
Open Questions ◽  
The Family

The last decade has seen an explosion of the family of framework materials and their study, both from the experimental and computational point of view. We propose here a short highlight of the current state of methodologies for modelling framework materials at multiple scales, putting together a brief review of new methods and recent endeavours in this area, as well as outlining some of the open challenges in this field. We will detail advances in atomistic simulation methods, the development of materials databases, and the growing use of machine learning for properties prediction.

scholarly journals Biomarkers in Posttraumatic Stress Disorder: Overview and Implications for Future Research

2013 ◽  
Vol 35 ◽  
pp. 43-54 ◽  
Author(s):  
Ulrike Schmidt ◽  
Sebastian F. Kaltwasser ◽  
Carsten T. Wotjak
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Sexual Abuse ◽  
Anxiety Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Future Research ◽  
Clinical Use ◽  
Current State ◽  
Life Threatening ◽  
State Of Research

PTSD can develop in the aftermath of traumatic incidents like combat, sexual abuse, or life threatening accidents. Unfortunately, there are still no biomarkers for this debilitating anxiety disorder in clinical use. Anyhow, there are numerous studies describing potential PTSD biomarkers, some of which might progress to the point of practical use in the future. Here, we outline and comment on some of the most prominent findings on potential imaging, psychological, endocrine, and molecular PTSD biomarkers and classify them into risk, disease, and therapy markers. Since for most of these potential PTSD markers a causal role in PTSD has been demonstrated or at least postulated, this review also gives an overview on the current state of research on PTSD pathobiology.

Sport in business studies: a state-of-the-art literature review

2018 ◽  
Vol 8 (5) ◽  
pp. 529-546
Author(s):  
Christofer Laurell ◽  
Sten Soderman
Keyword(s):  
Systematic Review ◽  
Literature Review ◽  
Marketing Strategy ◽  
Design Methodology ◽  
State Of The Art ◽  
Future Research ◽  
Content Type ◽  
Business Studies ◽  
Current State ◽  
State Of Research

PurposeThe purpose of this paper is to provide a systematic review of articles on sport published in leading business studies journals within marketing, organisational studies and strategy.Design/methodology/approachBased on a review of 38 identified articles within the subfields of marketing, strategy and organisation studies published between 2000 and 2015, the articles’ topical, theoretical and methodological orientation within the studied subfields were analysed followed by a cross-subfield analysis.FindingsThe authors identify considerable differences in topical, theoretical and methodological orientation among the studied subfields’ associated articles. Overall, the authors also find that articles across all subfields tend to be focussed on contributing to mature theory, even though the subfield of marketing in particular exhibits contributions to nascent theory in contrast to organisation studies and strategy.Originality/valueThis paper contributes by illustrating the current state of research that is devoted or related to the phenomenon of sport within three subfields in business studies. Furthermore, the authors discuss the role played by leading business studies journalsvis-à-vissport sector-specific journals and offer avenues for future research.

Evolutionary Approaches to Health Issues and Behaviors Across the Life Course

2019 ◽  
pp. 273-302
Author(s):  
Daniel J. Kruger ◽  
Jessica S. Kruger
Keyword(s):  
Evolutionary Theory ◽  
Life History Theory ◽  
Future Research ◽  
Health Issues ◽  
Current State ◽  
Health Related Research ◽  
Health Related ◽  
State Of Research ◽  
The Life Course ◽  
And Behavior

Health-related research is broad, diverse, and fragmented theoretically, methodologically, and across disciplines. The understanding and improvement of human health would be accelerated by establishing a universal and deep framework integrating varied undertakings. This framework is evolutionary theory, the most powerful explanatory system in the life sciences and the only framework that can unify knowledge in otherwise disparate fields of human research. Darwinian medicine has already made considerable progress in the practical understanding of human physiology and other areas informing medical care. Within evolutionary theory, life history theory in particular holds the promise of promoting understanding of variation in behavioral patterns related to health and why they vary consistent with environmental conditions. This chapter describes the current state of research exemplifying an evolutionary approach to health-related psychology and behavior and outlines directions for future research and intervention efforts.

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