Relationship of Asteroid Hyalosis to Diabetes Mellitus and Plasma Lipid Levels

1969 ◽  
Vol 67 (3) ◽  
pp. 406-413 ◽  
Author(s):  
Malcolm Luxenberg ◽  
David Sime
Keyword(s):  
Diabetes Mellitus ◽  
Plasma Lipid ◽  
Lipid Levels ◽  
Asteroid Hyalosis ◽  
Relationship Of

Plasma lipid levels in insulin-dependent diabetes mellitus

Diabetes Care ◽  
1979 ◽  
Vol 2 (1) ◽  
pp. 31-34 ◽  
Author(s):  
W. V. Moore ◽  
J. Knapp ◽  
R. L. Kauffman ◽  
W. G. Perkins
Keyword(s):  
Diabetes Mellitus ◽  
Plasma Lipid ◽  
Insulin Dependent Diabetes Mellitus ◽  
Insulin Dependent Diabetes ◽  
Dependent Diabetes Mellitus ◽  
Lipid Levels ◽  
Insulin Dependent

scholarly journals Sex Hormone-Binding Globulin Is Associated with Obesity and Dyslipidemia in Prepubertal Children

Children ◽  
2020 ◽  
Vol 7 (12) ◽  
pp. 272
Author(s):  
Gihong Park ◽  
Kyungchul Song ◽  
Youngha Choi ◽  
Jun Suk Oh ◽  
Han Saem Choi ◽  
...  
Keyword(s):  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Atherogenic Index ◽  
Hormone Binding ◽  
Lipid Levels ◽  
Prepubertal Children ◽  
Overweight Group ◽  
Relationship Of

Sex hormone-binding globulin (SHBG) is associated with age, sex, and puberty. The association of SHBG with various diseases has been suggested nowadays, however, the relationships in prepubertal children have not been sufficiently investigated. This study analyzed the relationship of SHBG with body mass index (BMI) and plasma lipid levels in prepubertal children. We evaluated the association of SHBG with BMI among the 693 prepubertal children subdivided into normal, overweight, and obese groups, with plasma lipid levels among the children subdivided into normal and dyslipidemia groups. The obese and overweight group had lower SHBG levels than the normal BMI group in both sexes. The dyslipidemia group included subjects with low high-density lipoprotein cholesterol (HDL-C), high triglycerides (TG), or a high atherogenic index of plasma (AIP); this group had lower SHBG than the normal lipid group. SHBG was positively correlated with HDL-C, and negatively correlated with TG and AIP. After adjusting for BMI, SHBG was positively correlated with HDL-C and negatively correlated with TG and AIP in all groups. In conclusion, SHBG levels are closely correlated with BMI in prepubertal children. SHBG may play a meaningful role in the decrease in HDL-C and increase in TG during prepubertal age.

scholarly journals Effect of metformin on blood lipids in patients with diabetes mellitus

2020 ◽  
Vol 13 (2) ◽  
pp. 23-27
Author(s):  
Tahniyah Haq ◽  
Sabah Haq
Keyword(s):  
Diabetes Mellitus ◽  
Blood Lipids ◽  
Plasma Lipid ◽  
Average Dose ◽  
Lipid Levels ◽  
Cross Sectional ◽  
Significant Difference ◽  
Patients With Diabetes ◽  
Group 2 ◽  
Group 1

Background and objectives: Metformin improves macrovascular complications in people with diabetes mellitus (DM). Although the exact mechanism is not known, metformin has beneficial effects on dyslipidaemia. The aim of the study was to find out if there was an effect of metformin on blood lipids in people with diabetes mellitus. Method: This was a cross-sectional study which included 80 patients with diabetes mellitus. They were divided into 2 groups – (a) Group 1: on metformin and (b) Group 2: without metformin medication. None of the patients were on any other anti-diabetic medication. All data were obtained from patients’ medical records. Individual blood lipids and lipid ratios were compared between two groups. Result: Group 1 included 42 patients with a mean HbA1c of 7.58 ± 0.24% taking an average dose of 820.83 ± 60.40 mg/day of metformin. Group 2 consisted of 38 patients with mean HbA1c of 7.58 ± 0.29%. There was no significant difference in individual plasma lipid levels, lipoprotein ratio or frequency of dyslipidaemia between patients taking and not taking metformin (p>0.05). Also, different doses of metformin had no significant effect on the plasma lipid levels. Conclusion: Metformin did not affect the lipid profile of patients with diabetes mellitus. Ibrahim Med. Coll. J. 2019; 13(2): 23-27

scholarly journals Exosomal microRNA Expression Profiling Analysis of the Effects of Lycium Barbarum Polysaccharide on Gestational Diabetes Mellitus Mice

2019 ◽  
Author(s):  
Ya Xiao ◽  
Weihao Chen ◽  
Ruixue Chen ◽  
Anling Luo ◽  
Dayi Chen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Expression Profiling ◽  
Plasma Lipid ◽  
Microrna Expression ◽  
Lipid Levels ◽  
Lycium Barbarum ◽  
Liver Histopathology ◽  
Exosomal Microrna

Abstract Background Gestational diabetes mellitus (GDM) is a pathological condition, affecting an increasing number of pregnant women worldwide. Safe and effective treatment for GDM is very important for the public health. In this study, we utilized a high-fat diet induced GDM model to evaluate the effects of LBP on GDM and examined the changes of exosomal microRNA expression profiling to decipher the potential underlying mechanism of LBP.Methods Female C57BL/6J mice were fed a control diet, HFD, or 150 mg/kg LBP- supplemented HFD for 6 weeks before conception and throughout gestation. Oral glucose tolerance test and plasma lipid levels were determined and liver histopathology was assessed. Sequencing was used to define the microRNA expression profiling of plasma exosomes in the three groups of mice and proteins expression levels of the candidate target genes were analyzed.Results LBP significantly relieved glucose intolerance, abnormal plasma lipid levels and pathomorphological changes of liver histopathology in HFD induced GDM mice. Moreover, we found that this effect of LBP was mediated by down-regulation of the increase of 6 miRNAs (miR-93-3p, miR-188-5p, miR-466k, miR-1188-5p, miR-7001-3p and miR-7115-5p) and reversing the increase protein expression of CPT1A, which is the target gene of miR-188-5p.Conclusions Our findings provide novel insights into the biological activities of LBP in the treatment of GDM.

Risk of type 2 diabetes mellitus associated with plasma lipid levels: The rural Chinese cohort study

2018 ◽  
Vol 135 ◽  
pp. 150-157 ◽  
Author(s):  
Ming Zhang ◽  
Junmei Zhou ◽  
Yu Liu ◽  
Xizhuo Sun ◽  
Xinping Luo ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cohort Study ◽  
Plasma Lipid ◽  
Lipid Levels ◽  
Chinese Cohort
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