Physiology and Diseases of the Thyroid Gland in the Elderly: Physiological Changes, Hypothyroidism, and Hyperthyroidism

2021 ◽  
pp. 191-248
Author(s):  
Emiliano Corpas ◽  
Franco Sánchez-Franco ◽  
Ricardo Correa ◽  
Karyne Vinales ◽  
Álvaro Larrad-Jiménez ◽  
...  
2020 ◽  
Vol 11 (04) ◽  
pp. 640-642
Author(s):  
Halil Onder

AbstractGait disorders are common in the elderly as there are various causes of neurological and non-neurological conditions. On the other hand, most of the gait parameters do change with advancing age which is identified as age-related physiological changes in gait. At this point, the discrimination between age-related physiological changes and gait disorders may be strictly challenging. After identifying gait as an abnormal pattern, classification of it and making the responsible pathophysiology also require high-level expertise in this regard. Herein, we present a rare patient with corticobasal degeneration (CBD) who had admitted initially due to complaints of gait problems. Over a long time, the patient had received the misdiagnosis of gait abnormality due to musculoskeletal problems by multiple physicians. However, the detailed neurological exam showed a higher level gait disorder (HLGD). Further investigations at this point yielded the diagnosis of CBD.


1983 ◽  
Vol 69 (3) ◽  
pp. 205-213 ◽  
Author(s):  
Carlo D. Baroni ◽  
Liborio Manente ◽  
Vincenzo Maccallini ◽  
Giorgio Di Matteo

The classification proposed by Woolner et al. (1961, 1971) has been applied to 139 cases of primary malignant tumors of the thyroid gland diagnosed in one of the largest hospitals of Rome, Italy, over a period of 5 years, from 1977 to 1981. These cases come from 1418 patients with enlargement of the thyroid surgically treated at the 5th Surgical Clinic of the University of Rome. All the histologic slides were re-examined, and the pathology records were re-evaluated. Of these tumors, 56.8% were papillary, 30.9% follicular, 9.3% anaplastic or undifferentiated, and 2.1% medullary. There was a female predominance in all age groups and for all types of tumors, reflecting a total female to male ratio of 1.9:1. Papillary carcinoma occurred most commonly in young and young-adult patients, follicular in the middle-age group, and anaplastic in the elderly. The extent of the primary tumor, the presence of regional metastases, and the association with other thyroid nonneoplastic diseases such as lymphocytic and Hashimoto's thyroiditis, and nontoxic and toxic goiter were also recorded. Multicentric rumors were found in 38.9% of cases principally represented by papillary carcinomas. Regional lymph node metastases were observed mainly in young patients, and no correlation was found between thyroid cancer incidence and other nonneoplastic thyroid diseases.


2017 ◽  
Vol 3 (4) ◽  
Author(s):  
Augusto P. Casani ◽  
Elena Navari

Disequilibrium is one of the most common complaints that older adults bring to their physician and falling is a frequent complication; because of the increasing number of elderly patients in western society the problem grows. The increasing susceptibility to falling can be consequence of age-related physiological changes and of a higher prevalence of comorbidities causing dizziness, vertigo and imbalance; these symptoms can worse the already poor balance of old adults increasing the risk of falling. Among the major reasons of vertigo and dizziness, central vertigo and orthostatic vertigo are very common; also vestibular disorders have a great role and are currently thought to account for 48% of dizziness reported by older adults. An early identification of the treatable condition underlying dizziness in elderly would surely ameliorate the outcome of these patients.


2021 ◽  
Vol 19 (2) ◽  
pp. 1-7
Author(s):  
Reginaldo José Carlini Junior ◽  
Silvia Alves da Silva ◽  
Suzana Alves da Silva Batista ◽  
Eduardo José da Silva

INTRODUÇÃO: O risco de quedas torna-se iminente com o envelhecimento e as repercussões inerentes a este evento se resumem, muitas vezes, em dependência e morte. Uma estratégia viável a ser utilizada junto aos idosos, com vistas a minimizar os efeitos do avanço da idade, principalmente o risco de quedas, é a implementação do exercício resistido. OBJETIVO: Investigar os benefícios do treinamento resistido na prevenção do risco de quedas em idosos. MÉTODOS: Por se tratar de uma revisão sistemática, foi realizada uma busca em quatro bases de dados: Pubmed, Lilacs, Scielo e Ebsco. Diante a proposta do estudo, 630 artigos foram encontrados e 7 selecionados, após aplicação dos critérios de inclusão e exclusão. Foram considerados como critérios de seleção os ensaios clínicos, nos quais o treinamento resistido foi implementado em idosos ativos sem relevantes patologias para a idade, como, por exemplo, diabetes, cardiopatias, distúrbios cognitivos e neuromusculares. Vale ressaltar que estudos com exercícios combinados como, por exemplo, aeróbico e resistido, foram excluídos. RESULTADOS: Após o período de intervenção foram observados, aumentos de força muscular, mobilidade, velocidade de deslocamento e otimizações nos equilíbrios dinâmico e estático. CONCLUSÃO: Os achados sugerem que o treinamento resistido apresenta ganhos substanciais no intuito de atenuar as mudanças fisiológicas e reduzir, potencialmente, o risco de quedas e fraturas em idosos. TITLE: Benefits of resistance exercise in preventing falls in the elderly: a systematic reviewABSTRACT BACKGROUND: The risk of falls becomes imminent with aging and the repercussions inherent to this event are often summarized in dependence and death. A viable strategy to be used with the elderly, in order to minimize the effects of advancing age, especially the risk of falls, is the implementation of resistance exercise. OBJECTIVE: To investigate the benefits of resistance training in preventing the risk of falls in the elderly. METHODS: As this is a systematic review, a search was performed in four databases: Pubmed, Lilacs, Scielo and Ebsco. In view of the study proposal, 630 articles were found and 7 selected, after applying the inclusion and exclusion criteria. Clinical trials were considered as selection criteria, in which resistance training was implemented in active elderly people without relevant pathologies for their age, such as, for example, diabetes, heart disease, cognitive and neuromuscular disorders. RESULTS: It is worth mentioning that studies with combined exercises such as, for example, aerobic and resistance, were excluded. After the intervention period, increases in muscle strength, mobility, displacement speed and optimizations in dynamic and static balances were observed. CONCLUSION: The findings suggest that resistance training has substantial gains in order to mitigate physiological changes and potentially reduce the risk of falls and fractures in the elderly.


Author(s):  
Edo Yudistira ◽  
Roza Mulyana

The senior population has a higher risk of contracting Covid-19 and is at risk ofdeveloping more severe disease. This is due to physiological changes in old age,which causes a decrease in immune function accompanied by an increase incomorbid disorders such as diabetes, hypertension, heart disease, lung disease,and dementia. WHO reports that the mortality rate for Covid-19 patients in theelderly above 80 years in China is around 21.9%, Italy is about 89% at the ageabove 70 years, and the United States is 85% at the age of 65 years and over.Delirium syndrome often appears as the primary complaint or infrequently; itoccurs on the first day the patient is treated and shows fluctuating symptoms.Symptoms of delirium, such as disorientation, difficulty concentrating, andinattention, often occur in the elderly and are associated with a poor prognosis.Management of geriatric patients with covid 19 must be carried out thoroughlyand completely, especially in geriatric patients with comorbidities. Managementincludes primary diseases, namely Covid-19 infection, delirium, nutritionaltherapy, blood sugar, family education for patient assistance, maintaining thepatient's body and environment cleanliness, oral hygiene, and, last but not least,moral support from the family for the patient. With complete management, elderlypatients with various comorbid can survive the Covid-19 infection.


Author(s):  
Faiza Nouh ◽  
Mariam Omar ◽  
Manal Younis ◽  
Moftah Younis

Background: Ageing brings various physiological and non physiological changes which influence the nutritional status. Methods: A cross-sectional study extended from 1st December 2007 to 15th April 2008 on elderly of both sexes attending public polyclinics in Benghazi city. Results: 6.5% was the prevalence of malnutrition. 36.8% was the percentage of elderly at risk of malnutrition. Age, sex, occupation, income inadequacy to food, oral problems, dysphagia, constipation and dehydration, activity level, chronic disease, food intolerances and BMI all these factors were the various physiological and non-physiological factors associated with the nutritional status of the subjects. Conclusions: Outpatients elderly in Benghazi should be routinely screened and assessed if needed, for malnutrition or its risk. 


2021 ◽  
pp. 295-363
Author(s):  
Álvaro Larrad-Jiménez ◽  
Franco Sánchez-Franco ◽  
Ricardo Correa ◽  
Karyne Vinales ◽  
Emiliano Corpas ◽  
...  

2021 ◽  
pp. 249-294
Author(s):  
Franco Sánchez-Franco ◽  
Emiliano Corpas ◽  
Ricardo Correa ◽  
Ming Li ◽  
Álvaro Larrad-Jiménez ◽  
...  

Author(s):  
Mahesh P. G. ◽  
Raman S. G.

AIM: Prasugrel is used to treat heart attack and strokes in persons with heart disease (recent heart attack). It helps keep blood flowing smoothly in your body. Objective: Difficulty in swallowing (dysphasia) is a common problem of all age groups, especially the elderly and pediatrics, because of physiological changes associated with these groups.


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