The study on relationship between polymorphism of LRP5 gene and peak BMD and obesity phenotypes in Chinese nuclear families

Bone ◽  
2008 ◽  
Vol 43 ◽  
pp. S63
Author(s):  
Jinbo Yu ◽  
Zhenlin Zhang ◽  
Jinwei He ◽  
et al.
Keyword(s):  
Bone ◽  
2009 ◽  
Vol 44 ◽  
pp. S118
Author(s):  
Z. Zhang ◽  
J. He ◽  
H. Yue ◽  
W. Hu ◽  
H. Zhang ◽  
...  
Keyword(s):  

Bone ◽  
2008 ◽  
Vol 43 ◽  
pp. S33
Author(s):  
Yu Jinbo ◽  
Zhang Zhenlin ◽  
He Jinwei ◽  
et-al
Keyword(s):  

2021 ◽  
Vol 12 ◽  
Author(s):  
Su-qin Shi ◽  
Shan-shan Li ◽  
Xiao-ya Zhang ◽  
Zhe Wei ◽  
Wen-zhen Fu ◽  
...  

ObjectiveThe current study was conducted to determine whether peak bone mineral density (BMD) and obesity phenotypes are associated with certain LGR4 gene polymorphisms found in Chinese nuclear families with female children.MethodsA total of 22 single nucleotide polymorphisms (SNPs) located in and around the LGR4 gene were identified in 1,300 subjects who were members of 390 Chinese nuclear families with female children. Then, BMD readings of the femoral neck, total hip, and lumbar spine as well as measurements of the total lean mass (TLM), total fat mass (TFM), and trunk fat mass were obtained via dual-energy X-ray absorptiometry. The quantitative transmission disequilibrium test was used to analyze the associations between specific SNPs and LGR4 haplotypes and peak BMD as well as between LGR4 haplotypes and TLM, percent lean mass, TFM, percent fat mass, trunk fat mass, and body mass index (BMI).ResultsHere, rs7936621 was significantly associated with the BMD values for the total hip and lumbar spine, while rs10835171 and rs6484295 were associated with the trunk fat mass and BMI, respectively. Regarding the haplotypes, we found significant associations between GAA in block 2 and trunk fat mass and BMI, between AGCGT in block 3 and total hip BMD, between TGCTCC in block 5 and femoral neck BMD, and between TACTTC in block 5 and both lumbar spine and femoral neck BMD (all P-values < 0.05).ConclusionGenetic variations of the LGR4 gene are related to peak BMD, BMI, and trunk fat mass.


2007 ◽  
Vol 19 (1) ◽  
pp. 39-47 ◽  
Author(s):  
Z.-L. Zhang ◽  
J.-W. He ◽  
Y.-J. Qin ◽  
Y.-Q. Hu ◽  
M. Li ◽  
...  

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Sunita ◽  
Urvashi Singh ◽  
Shalini Singh ◽  
Rajnee Sharma

The present study was conducted to examine the relationship between organisational stress and organisational citizenship behaviours (OCBs) in employees of call centers. The study also further explored as how stress at work set-up has negative impact on OCBs. A sample of 250 employees working in call centre of Gurgaon belonging to an age group of 25-30 years were selected on availability basis. All were working married couples living in nuclear families. Job stress survey (Spielberger & Vagg, 1999) and Organisational Citizenship Behaviour (Bateman & Organ, 1983) were administered. Data was analysed by using simple correlation and multiple regression. Results showed the negative relationship between organisational stress and OCBs. Results of regression analysis also exhibited the negative impact of stress on OCBs. The implications for the employees are discussed.


The present paper is an attempt to analyze the socio-economic profile of the labour households in rural Punjab. The study revealed that majority of rural labour households belonged to the scheduled caste category. As far as the distribution of sampled rural labour households according to the family type was concerned, it was found that 46.42 percent of the total rural labour households had nuclear families, while the remaining 53.58 percent have joint families. Majority of the rural labourers were living in semi-pucca houses. Further, if we look at the housing condition, 54.72 percent of rural labourers owned the houses of average condition, 40.19 percent owned good condition households and 5.09percent owned dilapidated houses. The analysis further showed that as many as 20.35percentof the sampled labour population was illiterate. A few persons from sampled labour households educated above matric. Although large majority of the sampled labour population were from the working-age group yet the ratio of dependents was high among rural labour households. This was due to lower employment opportunities in rural areas.


Author(s):  
Kamila Gieba

The article examines ways of representing nuclear catastrophe in Kate Brown's Plutopia: Nuclear Families, Atomic Cities, and the Great Soviet and American Plutonium Disasters. In 1957 an explosion in the Mayak works - a plutonium production site - led to massive contamination of the surrounding areas. The event remained a closely kept secret till 1992, absent from the public sphere and cultural texts, despite the fact that the scale of contamination was as big as the Chernobyl explosion. One of the reasons for this was the difficulty of representing nuclear radiation. The author focuses on three contexts of this impossibility: in relation to the cognitive theory of the metaphor, the figure of the sick body as bearer of memory, and the invisibility of the nuclear landscape.


2021 ◽  
pp. jech-2020-215319
Author(s):  
Petr Badura ◽  
Zdenek Hamrik ◽  
Maxim Dierckens ◽  
Inese Gobiņa ◽  
Marta Malinowska-Cieślik ◽  
...  

BackgroundPrevious research has linked adolescents’ participation in organised leisure-time activities (OLTAs) to better health and well-being. It remains unclear whether these associations can be observed consistently across social and socioeconomic strata and countries.MethodsThe present study used nine nationally representative samples of adolescents aged 11, 13 and 15 years (total n=55 429) from the 2017/2018 Health Behaviour in School-aged Children survey from Europe and Canada. Regression models with mixed effects to account for nested nature of data were applied to estimate: (1) the associations of social and socioeconomic factors with OLTA participation; (2) strengths of the associations between breadth and pattern of OLTA participation with health and well-being indicators, after adjustment for the social and socioeconomic factors.ResultsRates of OLTA participation varied by age, sex and country of adolescents. Participants from lower socioeconomic classes and non-nuclear families were less likely to participate in OLTAs across each of the nine countries. Moreover, breadth of OLTA participation was associated with higher well-being independent of socioeconomic status or family structure. All of the participation patterns were associated with higher life satisfaction, but sports (either alone or in combination with a non-sport OLTA) were also associated with fewer psychological complaints and excellent self-rated health.ConclusionAdolescents’ engagement in OLTAs was associated with adolescents’ subjective well-being regardless of country, age, sex and variance in social and socioeconomic factors. Policies aimed at increasing adolescents’ subjective well-being and OLTA participation should focus on adolescents from low socioeconomic classes and non-nuclear families.


1990 ◽  
Vol 22 (4) ◽  
pp. 501-506 ◽  
Author(s):  
F. Luna ◽  
V. Fuster

SummaryThe reproductive pattern of a sample of nuclear families from La Alpujarra (Andalusia, Spain) is analysed. The origin of the wife or consanguinity of the couple does not influence fertility. Variability in number of pregnancies is most closely associated with marriage duration followed by the wife's year of birth. Differences in the number of births are explained more by the number of pregnancies than by the number of miscarriages. The number of survivors to the first birthday is dependent on the number of births and to a lower extent on infant mortality. Data from incomplete families show that reproductive performance of the wife below the age of 45 cannot be accepted as a reliable estimate of complete reproduction.


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