The mode of action of bacteriocin CHQS, a high antibacterial activity bacteriocin produced by Enterococcus faecalis TG2

Food Control ◽  
2019 ◽  
Vol 96 ◽  
pp. 470-478 ◽  
Author(s):  
Shuo Cao ◽  
Renpeng Du ◽  
Fangkun Zhao ◽  
Huazhi Xiao ◽  
Ye Han ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Enterococcus Faecalis ◽  
Mode Of Action ◽  
High Antibacterial Activity

scholarly journals Evaluation of Samarium Doped Hydroxyapatite, Ceramics for Medical Application: Antimicrobial Activity

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
C. S. Ciobanu ◽  
S. L. Iconaru ◽  
C. L. Popa ◽  
M. Motelica-Heino ◽  
D. Predoi
Keyword(s):  
Electron Microscopy ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Enterococcus Faecalis ◽  
Medical Application ◽  
Inhibitory Effect ◽  
Linear Increase ◽  
High Antibacterial Activity ◽  
Hydroxyapatite Ceramics ◽  
Transmission Electron

Samarium doped hydroxyapatite (Sm:HAp),Ca10-xSmx(PO4)6(OH)2(HAp), bionanoparticles with differentxSmhave been successfully synthesized by coprecipitation method. Detailed characterization of samarium doped hydroxyapatite nanoparticles (Sm:HAp-NPs) was carried out using X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Fourier transform infrared spectroscopy (FTIR). The biocompatibility of samarium doped hydroxyapatite was assessed by cell viability. The antibacterial activity of the Sm:HAp-NPs was tested against Gram-negative bacteria (Pseudomonas aeruginosaandEscherichia coli) and Gram-positive bacteria (Enterococcus faecalisandStaphylococcus aureus). A linear increase of antimicrobial activity ofP. aeruginosahas been observed when concentrations of Sm:HAp-NPs in the samples withxSm=0.02were higher than 0.125 mg/mL. For Sm:HAp-NPs withxSm=0.05a significant increase of antibacterial activity onE. coliwas observed in the range 0.5–1 mg/mL. For low concentrations of Sm:HAp-NPs (xSm=0.05) from 0.031 to 0.125 mg/mL a high antibacterial activity onEnterococcus faecalishas been noticed. A growth of the inhibitory effect onS. aureuswas observed for all concentrations of Sm:HAp-NPs withxSm=0.02.

Structure and mode of action of the antimicrobial peptide arenicin

2008 ◽  
Vol 410 (1) ◽  
pp. 113-122 ◽  
Author(s):  
Jörg Andrä ◽  
Igor Jakovkin ◽  
Joachim Grötzinger ◽  
Oliver Hecht ◽  
Anna D. Krasnosdembskaya ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Antimicrobial Peptide ◽  
Lipid Bilayers ◽  
Mode Of Action ◽  
Solution Structure ◽  
Polymyxin B ◽  
Gram Negative Bacteria ◽  
Bacterial Killing ◽  
Gram Negative ◽  
High Antibacterial Activity

The solution structure and the mode of action of arenicin isoform 1, an antimicrobial peptide with a unique 18-residue loop structure, from the lugworm Arenicola marina were elucidated here. Arenicin folds into a two-stranded antiparallel β-sheet. It exhibits high antibacterial activity at 37 and 4 °C against Gram-negative bacteria, including polymyxin B-resistant Proteus mirabilis. Bacterial killing occurs within minutes and is accompanied by membrane permeabilization, membrane detachment and release of cytoplasm. Interaction of arenicin with reconstituted membranes that mimic the lipopolysaccharide-containing outer membrane or the phospholipid-containing plasma membrane of Gram-negative bacteria exhibited no pronounced lipid specificity. Arenicin-induced current fluctuations in planar lipid bilayers correspond to the formation of short-lived heterogeneously structured lesions. Our results strongly suggest that membrane interaction plays a pivotal role in the antibacterial activity of arenicin.

scholarly journals Sm:HAp Nanopowders Present Antibacterial Activity againstEnterococcus faecalis

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Carmen Steluta Ciobanu ◽  
Cristina Liana Popa ◽  
Daniela Predoi
Keyword(s):  
Antibacterial Activity ◽  
Enterococcus Faecalis ◽  
Bacterial Adhesion ◽  
Biological Applications ◽  
Xps Spectra ◽  
Synthesis Of Nanoparticles ◽  
Gram Positive Bacteria ◽  
High Antibacterial Activity ◽  
Bactericidal Effects ◽  
First Time

The synthesis of nanoparticles with inhibitory and bactericidal effects represents a great interest in development of new materials for biological applications. In this paper we present for the first time the synthesis ofCa10-xSmx(PO4)6(OH)2nanoparticles at low temperature and primary tests concerning the adherence ofEnterococcus faecalis ATCC 29212(gram-positive bacteria). All the XRD peaks were indexed in accordance with the hexagonal HAp in P63m space group. The EDAX spectrum and elemental mapping of O, P, Ca, and Sm demonstrate that all the elements were homogeneously distributed inCa10-xSmx(PO4)6(OH)2withxSm=0.03. The peaks at 347.3 eV, 532.1 eV, and 133.8 eV in the XPS spectra can be attributed to the binding energy of Ca 2p, O 1s, and P 2p. The peak at 1084.4 eV observed inCa10-xSmx(PO4)6(OH)2was attributed to the Sm 3d5/2. Bacterial adhesion was reduced onCa10-xSmx(PO4)6(OH)2sample when compared to pure HAp(xSm=0)and significant differences in bacterial adhesion on pure HAp(x=0)and Sm:HAp(xSm=0.01, xSm=0.03, and xSm=0.1)were observed. The bacterial adhesion decreased when the samarium concentrations increased. Finally, we demonstrate that the Sm:HAp nanopowder withxSm>0showed high antibacterial activity againstEnterococcus faecalis ATCC 29212.

scholarly journals Antibacterial Effects of Capparis decidua Fruit Mediated Selenium Nanoparticles

2020 ◽  
Vol 9 (40) ◽  
pp. 2947-2950
Author(s):  
Shabbarish Chockalingam ◽  
Preetha S ◽  
Jeevitha M ◽  
Lavanya Pratap
Keyword(s):  
Antibacterial Activity ◽  
Streptococcus Mutans ◽  
Enterococcus Faecalis ◽  
Antibacterial Properties ◽  
The Body ◽  
Selenium Nanoparticles ◽  
Zone Of Inhibition ◽  
Antibacterial Effects ◽  
High Antibacterial Activity ◽  
Capparis Decidua

BACKGROUND Capparis decidua and Selenium have several antibacterial properties along with other highly desirable properties, but for long they have not been explored. Nanoparticles are efficient in transporting drugs as they are easily absorbed by the body due to their small size. We wanted to evaluate the antibacterial activity of Capparis decidua mediated selenium nanoparticles against Streptococcus mutans, Lactobacillus, and Enterococcus faecalis. METHODS 4 wells were dug in three Petri dishes of Agar which were coated with a layer of bacteria, Streptococcus mutans, Lactobacillus and Enterococcus faecalis. The wells were filled with different amounts of the extract in the order of 50 µL, 100 µL and 150 µL with the fourth well having 50 µL of the antibiotic. Zone of inhibition was measured. RESULTS After the measurements were made, the results obtained showed good zone of inhibition against Streptococcus mutans, Lactobacillus and Enterococcus faecalis. CONCLUSIONS This study suggests that Capparis decidua fruit mediated with Selenium Nanoparticles have a high antibacterial activity. KEY WORDS Antibacterial Effects, Capparis decidua, Selenium, Nanoparticles

Phytochemical Evaluation and Screening of Cardiotonic, Antibacterial and Anthelmintic Activities of Sida cordifolia L.

2014 ◽  
Vol 7 (3) ◽  
pp. 2567-2573
Author(s):  
Sarella Prakash Nathaniel Kumar ◽  
Kanthal L.K. ◽  
Durga S ◽  
Achutha Rama Raju D ◽  
Satyavati K
Keyword(s):  
Antibacterial Activity ◽  
Rural Areas ◽  
Anthelmintic Activity ◽  
Diffusion Method ◽  
Frog Heart ◽  
Aqueous Extracts ◽  
Cardiotonic Activity ◽  
Herbal Products ◽  
High Antibacterial Activity ◽  
Sida Cordifolia

Several herbs are traditionally used in the treatment of a variety of ailments particularly in the rural areas, where herbal medicine is mainly the source of health care system. Many of these herbs havenot been assessed for safety or toxicity to tissue or organs of the mammalian recipients. An attempt is made to prove the efficacy of Sida cordifolia Linn., (a traditional medicinal plant chosen on the basis of ethnomedical knowledge) for its Cardiotonic, Antibacterial and Anthelmintic activities. Sida cordofolia Linn., is used traditionally, inter alia, in the treatment of various infections, asthma, diarrhoea, heart and stomach disorders. Cardiotonicactivity is performed using isolated Frog Heart Perfusion Technique. Antibacterial activity of the whole plant extracts were assessed by Agar well diffusion method against the strains of Bacillus subtilis, Escherichia coli, and Staphylococcus aureus. Anthelmintic activity was studied against Pheretima posthuma. Phytochemical screening of powdered plant material revealed thepresence of some secondary metabolites such as alkaloids, saponins, tannins, glycosides and flavonoids. Results indicated that methanol, chloroform, aqueous extracts have significant cardiotonic activity but less than standard drugs. Methanol and Aqueous extracts showed high antibacterial activity and anthelmintic activity than the standard drugs. In a nutshell, we can conclude that the methanol and aqueous fractions of Sida cordifolia Linn., had a profound antibacterial and anthelmintic effect eventhough it possessed very significant cardiotonic activity. This validates its continuous usage in ethnomedicine. This plant could be developed into cheap, safe and culturally acceptable standardized herbal products and may serve as asource of new molecules for broad-spectrum antimicrobial and anthelmintic agent.

Bicomponent multifilament yarns of recycled poly(ethylene terephthalate) and nano-titanium dioxide for antibacterial carpet

2021 ◽  
pp. 152808372110117
Author(s):  
Sommai Pivsa-Art ◽  
Komson Sunyikhan ◽  
Weraporn Pivsa-Art
Keyword(s):  
Antibacterial Activity ◽  
Titanium Dioxide ◽  
Ethylene Terephthalate ◽  
Antibacterial Properties ◽  
Nano Structure ◽  
Elongation At Break ◽  
High Antibacterial Activity ◽  
Poly Ethylene Terephthalate ◽  
Poly Ethylene ◽  
Multifilament Yarns

Recycled poly(ethylene terephthalate) (RPET) multifilament yarns are used in carpet manufacturing as a way to reduce plastic waste. The conventional RPET carpet is however susceptible to bacterial accumulation. As a result, this research experimentally doped RPET with nano-structure titanium dioxide (nano-TiO2) to produce RPET/nano-TiO2 bicomponent multifilament yarns with antibacterial property. The experimental multifilament yarn structure consisted of two parts: neat RPET core and RPET/nano-TiO2 shell. The nano-TiO2 content in the shell was varied between 1 and 3 wt% and the core/shell (C/S) ratios between 90/10, 70/30, and 50/50 w/w. The effects of C/S ratio and nano-TiO2 content on the mechanical and antibacterial properties of bicomponent multifilament yarns were determined. The experimental results indicated that the C/S ratio had no effect on the tenacity and elongation at break. Meanwhile, the tenacity and elongation at break of bicomponent fibers increased with nano-TiO2 content in the shell. The TiO2-doped RPET bicomponent yarns effectively inhibited the growth of Escherichia coli and Staphylococcus aureus. The 90/10 bicomponent multifilament fiber with 3 wt% TiO2 achieved the highest antibacterial activity. The very high antibacterial activity was attributable to greater deposition of nano-TiO2 particles near and on the shell surface.

scholarly journals Monomyristin and Monopalmitin Derivatives: Synthesis and Evaluation as Potential Antibacterial and Antifungal Agents

Molecules ◽  
2018 ◽  
Vol 23 (12) ◽  
pp. 3141 ◽  
Author(s):  
Jumina ◽  
Asma Nurmala ◽  
Anggit Fitria ◽  
Deni Pranowo ◽  
Eti Sholikhah ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Positive Control ◽  
Antifungal Activities ◽  
Amberlyst 15 ◽  
Antibacterial And Antifungal Activities ◽  
High Antibacterial Activity ◽  
Carbon Chains ◽  
Acyl Position ◽  
Antibacterial And Antifungal ◽  
Isopropylidene Glycerol

In the present work, monoacylglycerol derivatives, i.e., 1-monomyristin, 2-monomyristin, and 2-monopalmitin were successfully prepared from commercially available myristic acid and palmitic acid. The 1-monomyristin compound was prepared through a transesterification reaction between ethyl myristate and 1,2-O-isopropylidene glycerol, which was obtained from the protection of glycerol with acetone, then followed by deprotection using Amberlyst-15. On the other hand, 2-monoacylglycerol derivatives were prepared through enzymatic hydrolysis of triglycerides in the presence of Thermomyces lanuginosa lipase enzymes. The synthesized products were analyzed using fourier transform infrared (FTIR) spectrophotometer, gas or liquid chromatography-mass spectrometer (GC-MS or LC-MS), and proton and carbon nuclear magnetic resonance (1H- and 13C-NMR) spectrometers. It was found that monomyristin showed high antibacterial and antifungal activities, while 2-monopalmitin did not show any activity at all. The 1-monomyristin compound showed higher antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also higher antifungal activity against Candida albicans compared to the positive control. Meanwhile, 2-monomyristin showed high antibacterial activity against Escherichia coli. The effect of the acyl position and carbon chains towards antibacterial and antifungal activities was discussed.

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