Stability and functionality of xanthan gum–shellac nanoparticles for the encapsulation of cinnamon bark extract

One of the natural ingredients can be used for sunscreen is Cinnamomum burmannii. Sinamaldehid chemical constituents in cinnamon bark extract that has potential as an antioxidant and can be used as a sunscreen content. This study was to determine the levels of cinnamon bark extract ( 1 %, 2 % and 3 % ) which can give physical characteristics, acceptability, which is optimal for preparations with HPMC as a gelling agent, Evaluations include pH, the power spread, the viscosity and acceptability. The results of organoleptic for formula I (1%), II (2%) and III (3%) have a soft texture grainy, the distinctive smell of cinnamon, and all formula has a pale brown color. From the analysis of One-Way ANOVA found significant differences for any dispersive power. But did not have significant differences in pH and viscosity. For acceptability evaluation formula III is the optimal formula to applied softness, easiest formula to flattened and easy to wash.

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Assessment of Cinnamon (Cinnamomum verum) Bark Extract on Proximate Composition and Sensory Qualities of Smoked-Dried African Catfish Clarias gariepinus (Burchell, 1822)

Asian Journal of Fisheries and Aquatic Research ◽

10.9734/ajfar/2021/v14i130285 ◽

2021 ◽

pp. 1-6

Author(s):

M. Y. Haruna ◽

M. M. Bello ◽

M. A. Dadile ◽

A. M. Mohammed

Keyword(s):

Sensory Evaluation ◽

Proximate Composition ◽

Clarias Gariepinus ◽

Economic Loss ◽

Mean Value ◽

Carbohydrate Content ◽

Bark Extract ◽

African Catfish ◽

Cinnamon Bark ◽

Extract Solution

The study determined the effect of Cinnamon (Cinnamonum verum) bark extract solution on proximate composition and sensory evaluation of smoke-dried catfish stored at ambient temperature (37+2oC) for 28 days. The experimental treatments are the control, 0.5%, 1% and 1.5 %( w/v) cinnamon bark extract solutions. Thirty-nine fish of average mean weight of 24.87+1.25g were gutted, washed and randomly assigned to the treatments. Thereafter, the fish were soaked into the treatments for 30minutes and later hot smoked for 12hours. After smoking, the fish were stored in boxes and placed on laboratory table for one month. The catfish Clarias gariepinus treated with 1% solution of Cinnamon bark extract had the highest moisture content with mean value 13.65+0.82%, followed by 6.93+1.66% recorded in fish sample treated with 1.5% solution of the extract, lowest percentage crude protein content 38.15+0.82% was observed in fish treated with 1% concentrate of the extract and percentage carbohydrate content indicate that the control have the lowest carbohydrate content with mean value 1.92+0.01% which is significantly different (p<0.05) from other treated sample while sample treated with 1.5% solution of the Cinnamon bark extract have the highest percentage carbohydrate with mean value 15.73+1.64%.Sensory evaluation was also assessed using 7-point hedonic scale and reveals that the smoked catfish retained very good score for appearance, colour, flavour, texture and general acceptance after 28days of storage and the overall acceptability mean score in fish treated with 5g and 15g cinnamon bark extract solution indicate the product is being generally accepted (2.87+0.59%) and (2.34+0.56%) respectively. Cinnamon (Cinnamonum verum) bark extract solution could be used to protect stored smoke-dried catfish from loss of nutritional value and general acceptability thus limiting economic loss and possible health risk to consumers.

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Efficacy and safety of the topical use of intranasal cinnamon bark extract in seasonal allergic rhinitis patients: A double-blind placebo-controlled pilot study

Journal of Herbal Medicine ◽

10.1016/j.hermed.2013.12.002 ◽

2014 ◽

Vol 4 (1) ◽

pp. 37-47 ◽

Cited By ~ 7

Author(s):

Sanjiv Walanj ◽

Aparna Walanj ◽

Vishwaraman Mohan ◽

Prasad Arvind Thakurdesai

Keyword(s):

Allergic Rhinitis ◽

Pilot Study ◽

Seasonal Allergic Rhinitis ◽

Bark Extract ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Cinnamon Bark

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EFFICACY AND SAFETY OF STANDARDIZED CINNAMON BARK EXTRACT FOR THE PREVENTION OF CHEMOTHERAPY-INDUCED WEIGHT LOSS AND ALOPECIA IN PATIENTS WITH BREAST CANCER: A RANDOMIZED, DOUBLE-BLIND, AND PLACEBO-CONTROLLED STUDY

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2019.v12i10.28246 ◽

2019 ◽

pp. 163-168

Author(s):

AJAY MEHTA ◽

SUCHITRA MEHTA ◽

PRASAD THAKURDESAI

Keyword(s):

Breast Cancer ◽

Weight Loss ◽

Side Effects ◽

Cancer Patients ◽

Outcome Measures ◽

Bark Extract ◽

Efficacy And Safety ◽

Breast Cancer Patients ◽

Double Blind ◽

Cinnamon Bark

Objective: The objective of the study was to evaluate the effects of IND02 (standardized Cinnamon bark extract) supplementation for the prevention of side effects of cancer chemotherapy in female patients with breast cancer. Methods: The study was conducted using double-blind, placebo-controlled design in 34 female breast cancer patients during the first 4 consecutive 21-day cycles of the standard chemotherapy regimen. The active treatment (IND02 capsules, 400 mg, one capsule, and thrice a day) or matching placebo was orally administrated in randomized (1:1 ratio) patients. The efficacy outcome measures were reduction in chemotherapy-induced weight loss, alopecia (hair fall), and other side effects. The safety outcome measures were hematology, ECG, vital signs, adverse event monitoring, and laboratory safety measurements. Results: The patients on the treatment with IND02 had shown significant protection from chemotherapy-induced severe weight loss (cachexia) and alopecia (reduced hair density and % hairs in the anagen phase, and increased % hairs in telogen phase) which was seen in the placebo group. IND02 treatment was found safe and well-tolerated during the study. Conclusion: Concomitant use of IND02 in breast cancer patients during breast cancer chemotherapy showed a clinical promise regarding efficacy and safety in preventing chemotherapy-induced weight loss and alopecia.

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Antimicrobial Efficacy of Poly (DL-lactide-co-glycolide) (PLGA) Nanoparticles with Entrapped Cinnamon Bark Extract againstListeria monocytogenesandSalmonella typhimurium

Journal of Food Science ◽

10.1111/1750-3841.12069 ◽

2013 ◽

Vol 78 (4) ◽

pp. N626-N632 ◽

Cited By ~ 42

Author(s):

Laura E. Hill ◽

T. Matthew Taylor ◽

Carmen Gomes

Keyword(s):

Plga Nanoparticles ◽

Antimicrobial Efficacy ◽

Bark Extract ◽

Cinnamon Bark

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Uji efek antibakteri ekstrak kulit kayu manis (Cinnamomum burmannii) terhadap Escherichia coli dan Streptococcus pyogenes

Jurnal e-Biomedik ◽

10.35790/ebm.4.1.2016.12204 ◽

2016 ◽

Vol 4 (1) ◽

Author(s):

Noviano B. Reppi ◽

Christi Mambo ◽

Jane Wuisan

Keyword(s):

Escherichia Coli ◽

Streptococcus Pyogenes ◽

Antibacterial Effect ◽

Bark Extract ◽

Inhibitory Zone ◽

Antibacterial Compounds ◽

Cinnamon Bark ◽

E Coli ◽

Inhibition Zones ◽

Cinnamomum Burmannii

Abstract: Cinnamon (Cinnamomum burmannii) is a natural substance that has been known as one of the spices, but later known as traditional medicine. Cinnamon bark contains several antibacterial compounds, such as eugenol and cinnamaldehyde. There were two species of bacteria used in this study, Escherichia coli and Streptococcus pyogenes. These bacteria represent negative Gram bacteria and positive gram bacteria. The study aimed to determine antibacterial effect of cinamon bark againts E.coli and S.pyogenes by measuring the diameters of the inhibition zones. Cinamon bark samples were taken from Kaneyan, South Minahasa, and then be extracted by maceration using 80% etanol. The results showed that the total diameter of the inhibitory zone of Cinamon bark extract against E.coli was 43 mm with an average of 14,3 mm, and the total diameter of the inhibitory zone against S.pyogenes was 75 mm with an average of 25 mm. Conclusion: Cinamon bark extract had antibacterial effect against E Escherichia coli and Streptococcus pyogenes. Keywords: cinamon bark, escherichia coli, streptococcus pyogenes,antibacterial effect. Abstrak: Kayu manis (Cinnamomum burmannii) merupakan bahan alami yang selama ini hanya dikenal sebagai bumbu dalam masakan, tetapi ternyata memiliki khasiat obat. Kulit kayu manis mengandung beberapa senyawa yang bersifat antibakteri, seperti eugenol dan cinnamaldehyde. Bakteri Escherichia coli dan Streptococcus pyogenes merupakan bakteri yang digunakan didalam peneilitian ini. Kedua bakteri ini mewakili bakteri Gram negatif dan positif. Penelitian ini bertujuan untuk mengetahui efek antibakteri kulit kayu manis terhadap E. coli dan S. pyogenes, yang dinilai dari besarnya zona hambat yang terbentuk. Jenis penelitian ini eksperimental dengan metode sumuran Kirby-Bauer. Sampel kulit kayu manis diambil dari daerah Kaneyan Kabupaten Minahasa Selatan, kemudian diekstraksi dengan metode maserasi menggunakan pelarut etanol 80%. Hasil penelitian memperlihatkan diameter zona hambat total dari ekstrak kulit kayu manis terhadap E. coli sebesar 43mm dengan rerata 14,3mm, dan terhadap S. pyogenes diameter zona hambat total 75mm dengan rerata 25mm. Simpulan: Ekstrak kulit kayu manis memiliki efek antibakteri dalam menghambat pertumbuhan Escherichia coli dan Streptococcus pyogenesKata kunci: kulit kayu manis, Escherichia coli, Streptococcus pyogenes, antibakteri

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Application of Plant Extracts as a Preservative in an Aqueous Gel Formulation

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.859.172 ◽

2020 ◽

Vol 859 ◽

pp. 172-180

Author(s):

Punnidtha Bupphatanarat ◽

Worrapannee Powtongsook ◽

Chawalinee Asawahame ◽

Paveena Wongtrakul

Keyword(s):

Antimicrobial Activities ◽

Hexane Extract ◽

Diffusion Method ◽

Bark Extract ◽

Bacterial Strains ◽

Bioactive Constituents ◽

Cinnamon Bark ◽

Effective Doses ◽

Challenge Tests ◽

Micro Organisms

This research aims to study the antimicrobial activities of five selected plants, which were cinnamon bark, betel leaves, licorice, ginger, and galangal and select the most effective herbal extracts to be evaluated for their preservative efficacies in aqueous gel formulation. The sequential solvent extraction using hexane and 95% ethanol was used to extract bioactive constituents in the studied plants. After completely evaporated the solvents, the crude extracts were tested for the antimicrobial activities against S.aureus TISTR 1466 (ATCC 6538), P.aeruginosa TISTR 781 (ATCC 9027), E.coli ATCC 7839, C.albicans TISTR 5779 (ATCC 10201) and A.brasiliensis DMST 15538 (ATCC 16404) by agar well diffusion method. The result showed that the cinnamon bark extract macerated in hexane could inhibit the growth of all studied micro-organisms and was more effective than betel leaves, ginger, galangal and licorice extracts, while its 95% ethanolic extracts obviously showed lower antimicrobial activities. The MIC and MBC or MFC of cinnamon bark extract against the testing micro-organisms were in a range of 0.039-0.312 mg/mL and 0.156-1.250 mg/mL/0.078-0.625 mg/mL, respectively. The effective doses of hexane extract of cinnamon bark attempted to be tested as preservative in aqueous gel formulation were 0.3%, 1.25% and 2.5% by weight, which were equal to MIC, 4MIC and 8MIC, respectively. The challenge tests according to ISO 11930 were carried out to determine the preservative efficacy. The results revealed that 1.25% and 2.5% of cinnamon bark extract satisfied the criteria B for bacterial strains and the criteria A for yeast and mold. The LC-MS data confirmed that the two main constituents in hexane extract of cinnamon bark were coumarin and cinnamaldehyde that might play a role in antimicrobial activity.

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