Immobilization of mannanase on sodium alginate-grafted-β-cyclodextrin: An easy and cost effective approach for the improvement of enzyme properties

2020 ◽  
Vol 156 ◽  
pp. 1347-1358 ◽  
Author(s):  
Shikha Dhiman ◽  
Binti Srivastava ◽  
Gursharan Singh ◽  
Madhu Khatri ◽  
Shailendra Kumar Arya
2019 ◽  
Vol 118 (6) ◽  
pp. 90-93
Author(s):  
L. Terina Grazy ◽  
Dr.G. Parimalarani

E-commerce is a part of Internet Marketing. The arrival of Internet made the world very simple and dynamic in all the areas. Internet is the growing business as a result most of the people are using it in their day to day life. E-commerce is attractive and efficient way for both buyers and sellesr as it reduce cost, time and energy for the buyer. No surprise the insurance sector has become quite active within the internet sphere. Most insurance companies are offering policies to be brought online and also the portals for paying premiums. It actually saves from hassles involved in going to an insurance office and spend hours to get the insurance work done. Insurance has become an important and crucial aspect of life. Online insurance is the best and most cost effective approach of taking the insurance deal. This paper focused on influence of online marketing on the insurance industry in India, usage of internet in India , the internet penetration in India and the online sale of insurance product by the insurance sector.


2020 ◽  
Vol 23 (7) ◽  
pp. 587-598 ◽  
Author(s):  
Ahmed Refaat ◽  
Hanan Elhaes ◽  
Nabila S. Ammar ◽  
Hanan S. Ibrahim ◽  
Medhat Ibrahim

Aim and Objective: Wastewater treatment/remediation is a very important process that has a great environmental and economic impact. Therefore, it is crucial to innovate different methods to remove pollutants of different sources from wastewater. This work was conducted in order to study the removal of lead (Pb+2) from wastewater using microspheres of composites of sodium alginate, cellulose and chitosan, as well as using a cost-effective green route through composites of sodium alginate and dried water hyacinth. Materials and Methods: Molecular modeling at B3LYP/6-31g(d,p) was utilized to study sodium alginate, cellulose and chitosan. Sodium alginate was cross-linked with calcium chloride to form microspheres, then both sodium alginate/cellulose and sodium alginate/chitosan were also crosslinked as 50/50 to form microspheres. The roots of the aquatic plant water hyacinth in dry form were added to the cross-linked sodium alginate for up to 70%. SEM and FTIR were employed to study the surface of the prepared microspheres and their structures respectively. Atomic absorption spectroscopy was used to study the levels of Pb. Results: Molecular modeling indicated that the blending of such structures enhances their ability to bind with surrounding molecules owing to their ability to form hydrogen bonds. SEM results indicated that homogeneous structures of cellulose and chitosan are deformed when blended with sodium alginate, and FTIR confirmed the proper formation of the desired blends. Microspheres from sodium alginate showed the ability to remove Pb+2 from wastewater. SEM indicated further deformation in the morphology with the roughness of sodium alginate/water hyacinth microspheres, while FTIR confirmed the uniform matrices of the microspheres. The removal of Pb+2 was enhanced because of the addition of dried water hyacinth's roots. Conclusion: Modeling, experimental and kinetic data highlight sodium alginate/water hyacinth root as a green route to remediate Pb+2 from wastewater.


Author(s):  
Yana van der Meulen Rodgers

Chapter 7 concludes by highlighting the three biggest messages from the analysis presented in this book: (1) the global gag rule has failed to achieve its goal of reducing abortions; (2) restrictive legislation is associated with more unsafe abortions; and (3) the expanded global gag rule is likely to have negative repercussions across a range of health outcomes for women, children, and men. They are simple but powerful messages that should be heard by policymakers over the voices calling for an ideologically based policy that fails to achieve its desired outcome. The chapter closes with a more constructive and cost-effective approach for US family-planning assistance that targets integrated reproductive health services.


2021 ◽  
Vol 10 (5) ◽  
pp. 971
Author(s):  
Kristoff Hammerich ◽  
Jens Pollack ◽  
Alexander F. Hasse ◽  
André El Saman ◽  
René Huber ◽  
...  

Background: A major disadvantage of current spacers for two-stage revision total knee arthroplasty (R-TKA) is the risk of (sub-) luxation during mobilization in the prosthesis-free interval, limiting their clinical success with detrimental consequences for the patient. The present study introduces a novel inverse spacer, which prevents major complications, such as spacer (sub-) luxations and/or fractures of spacer or bone. Methods: The hand-made inverse spacer consisted of convex tibial and concave femoral components of polymethylmethacrylate bone cement and was intra-operatively molded under maximum longitudinal tension in 5° flexion and 5° valgus position. Both components were equipped with a stem for rotational stability. This spacer was implanted during an R-TKA in 110 knees with diagnosed or suspected periprosthetic infection. Postoperative therapy included a straight leg brace and physiotherapist-guided, crutch-supported mobilization with full sole contact. X-rays were taken before and after prosthesis removal and re-implantation. Results: None of the patients experienced (sub-) luxations/fractures of the spacer, periprosthetic fractures, or soft tissue compromise requiring reoperation. All patients were successfully re-implanted after a prosthesis-free interval of 8 weeks, except for three patients requiring an early exchange of the spacer due to persisting infection. In these cases, the prosthetic-free interval was prolonged for one week. Conclusion: The inverse spacer in conjunction with our routine procedure is a safe and cost-effective alternative to other articulating or static spacers, and allows crutch-supported sole contact mobilization without major post-operative complications. Maximum longitudinal intra-operative tension in 5° flexion and 5° valgus position appears crucial for the success of surgery.


Agronomy ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 918
Author(s):  
Xingzhe Cai ◽  
Meng Wang ◽  
Yucong Jiang ◽  
Changhu Wang ◽  
David W. Ow

Cadmium pollution threatens food safety and security by causing health issues and reducing farmland availability. Engineering genetic changes in crop plants to lower Cd accumulation can be a cost-effective approach to address this problem. Previously, we reported that a rice line, 2B, which expresses a truncated version of OsO3L2 had reduced Cd accumulation throughout the plant, including in seed. However, downstream events caused by expression of this gene were not known. In this study, RNA-seq was used to identify differentially expressed genes between the wild type and 2B rice with or without Cd treatment, leading to the study of an ABC transporter gene, OsABCG48 (ATP-Binding Cassette transporter G family member 48). Heterologous expression of OsABCG48 conferred tolerance to Cd in Schizosaccharomyces pombe, Arabidopsis and rice. Moreover, overexpressing OsABCG48 in rice lowered root Cd accumulation that was associated with more extensive lateral root development. These data suggest that OsABCG48 might have applications for engineering low-Cd rice.


The Analyst ◽  
2021 ◽  
Author(s):  
Diwakar M. Awate ◽  
Cicero C. Pola ◽  
Erica Shumaker ◽  
Carmen L Gomes ◽  
Jaime Javier Juarez

Despite having widespread application in the biomedical sciences, flow cytometers have several limitations that prevent their application to point-of-care (POC) diagnostics in resource-limited environments. 3D printing provides a cost-effective approach...


2013 ◽  
Vol 2013 ◽  
pp. 1-14 ◽  
Author(s):  
Amitava Ghosh ◽  
Prithviraj Chakraborty

Objective. Frusemide loaded calcium alginate micropellets, an oral microparticulate delivery system, was statistically optimized exhibiting prolonged therapeutic action minimizing its adverse effects.Methods. Ionotropic Gelation technique was adopted employing 32Factorial designs and keeping the entire process free from organic solvents. Physicochemical and the release characteristics of the prepared formulations were studied, keeping variations only in sodium alginate (primary polymer) and Acrycoat E30D (copolymer) dispersion.Result. Sodium alginate was predominant over Acrycoat E30D in all batches. Nonadditives or interaction was observed to be insignificant. Multiple regressions produced second-order polynomial equation, and the predictive results obtained were validated with high degree of correlation. Thein vivostudy applauded that optimized calcium alginate micropellets of frusemide can produce a much greater diuretic effect over an extended period of 24 hours.Conclusion. This study reveals that the potential of a single dose of the mathematically optimized micro pellets of frusemide formulation is sufficient in the management of peripheral edema and ascites in congestive heart failure and as well in the treatment of chronic hypertension, leading to better patient compliance, and can be produced with minimum experimentation and time, proving far more cost-effective formulation than the conventional methods of formulating dosage forms.


Sign in / Sign up

Export Citation Format

Share Document